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4LC5
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STRUCTURAL BASIS OF SUBSTRATE SPECIFICITY OF CDA SUPERFAMILY GUANINE DEAMINASE
Descriptor:Cytidine and deoxycytidylate deaminase zinc-binding region, ZINC ION, 9-METHYLGUANINE, ...
Authors:Bitra, A., Biswas, A., Anand, R.
Deposit date:2013-06-21
Release date:2014-01-22
Method:X-RAY DIFFRACTION (1.97 Å)
Cite:Structural basis of the substrate specificity of cytidine deaminase superfamily Guanine deaminase
Biochemistry, 52, 2013
4LCO
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CRYSTAL STRUCTURE OF NE0047 WITH COMPLEX WITH SUBSTRATE AMMELINE
Descriptor:Cytidine and deoxycytidylate deaminase zinc-binding region, ZINC ION, 4,6-diamino-1,3,5-triazin-2-ol
Authors:Bitra, A., Biswas, A., Anand, R.
Deposit date:2013-06-22
Release date:2014-01-22
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Structural basis of the substrate specificity of cytidine deaminase superfamily Guanine deaminase
Biochemistry, 52, 2013
4LCP
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CRYTSAL STRUCTURE OF NE0047 IN COMPLEX WITH 2,6-DIAMINOPURINE
Descriptor:Cytidine and deoxycytidylate deaminase zinc-binding region, ZINC ION, 9H-PURINE-2,6-DIAMINE
Authors:Bitra, A., Biswas, A., Anand, R.
Deposit date:2013-06-22
Release date:2014-01-22
Last modified:2017-11-15
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural basis of the substrate specificity of cytidine deaminase superfamily Guanine deaminase
Biochemistry, 52, 2013
4LD2
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CRYSTAL STRUCTURE OF NE0047 IN COMPLEX WITH CYTIDINE
Descriptor:Cytidine and deoxycytidylate deaminase zinc-binding region, ZINC ION, 4-AMINO-1-BETA-D-RIBOFURANOSYL-2(1H)-PYRIMIDINONE, ...
Authors:Bitra, A., Biswas, A., Anand, R.
Deposit date:2013-06-24
Release date:2014-01-22
Method:X-RAY DIFFRACTION (1.55 Å)
Cite:Structural basis of the substrate specificity of cytidine deaminase superfamily Guanine deaminase
Biochemistry, 52, 2013
4LD4
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CRYSTAL STRUCTURE OF NE0047 IN COMPLEX WITH CYTOSINE
Descriptor:Cytidine and deoxycytidylate deaminase zinc-binding region, ZINC ION, 6-AMINOPYRIMIDIN-2(1H)-ONE
Authors:Bitra, A., Biswas, A., Anand, R.
Deposit date:2013-06-24
Release date:2014-01-22
Method:X-RAY DIFFRACTION (3 Å)
Cite:Structural basis of the substrate specificity of cytidine deaminase superfamily Guanine deaminase
Biochemistry, 52, 2013
6MKB
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CRYSTAL STRUCTURE OF MURINE 4-1BB LIGAND
Descriptor:Tumor necrosis factor ligand superfamily member 9, SODIUM ION, N-ACETYL-D-GLUCOSAMINE, ...
Authors:Bitra, A., Zajonc, D.M., Doukov, T.
Deposit date:2018-09-25
Release date:2018-12-19
Last modified:2019-02-20
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Crystal structure of the m4-1BB/4-1BBL complex reveals an unusual dimeric ligand that undergoes structural changes upon 4-1BB receptor binding.
J. Biol. Chem., 294, 2019
6MKZ
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CRYSTAL STRUCTURE OF MURINE 4-1BB/4-1BBL COMPLEX
Descriptor:Tumor necrosis factor ligand superfamily member 9, Tumor necrosis factor receptor superfamily member 9, N-ACETYL-D-GLUCOSAMINE, ...
Authors:Bitra, A., Zajonc, D.M., Doukov, T.
Deposit date:2018-09-26
Release date:2018-12-19
Last modified:2019-02-20
Method:X-RAY DIFFRACTION (2.65 Å)
Cite:Crystal structure of the m4-1BB/4-1BBL complex reveals an unusual dimeric ligand that undergoes structural changes upon 4-1BB receptor binding.
J. Biol. Chem., 294, 2019
4LCN
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CRYTSAL STRUCTURE OF NE0047 IN COMPLEX WITH 2'-DEOXY-GUANOSINE
Descriptor:Cytidine and deoxycytidylate deaminase zinc-binding region, ZINC ION, 2'-DEOXY-GUANOSINE, ...
Authors:Anand, R., Bitra, A., Biswas, A.
Deposit date:2013-06-22
Release date:2014-01-22
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structural basis of the substrate specificity of cytidine deaminase superfamily Guanine deaminase
Biochemistry, 52, 2013
4HRQ
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IDENTIFICATION OF FUNCTION AND MECHANISTIC INSIGHTS OF GUANINE DEAMINASE FROM NITROSOMONAS EUROPAEA: ROLE OF THE C-TERMINAL LOOP IN CATALYSIS
Descriptor:Cytidine and deoxycytidylate deaminase zinc-binding region, 5-AMINO-1H-[1,2,3]TRIAZOLO[4,5-D]PYRIMIDIN-7-OL, ZINC ION
Authors:Anand, R., Bitra, A., Bhukya, H., Tanwar, A.S.
Deposit date:2012-10-28
Release date:2013-06-19
Last modified:2017-11-15
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Identification of function and mechanistic insights of guanine deaminase from Nitrosomonas europaea: role of the C-terminal loop in catalysis
Biochemistry, 52, 2013
4HRW
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IDENTIFICATION OF FUNCTION AND MECHANISTIC INSIGHTS OF GUANINE DEAMINASE FROM NITROSOMONAS EUROPAEA
Descriptor:Cytidine and deoxycytidylate deaminase zinc-binding region, ZINC ION, 5-AMINO-1H-[1,2,3]TRIAZOLO[4,5-D]PYRIMIDIN-7-OL
Authors:Anand, R., Bitra, A., Bhukya, H., Tanwar, A.S.
Deposit date:2012-10-29
Release date:2013-06-19
Last modified:2017-11-15
Method:X-RAY DIFFRACTION (2.43 Å)
Cite:Identification of function and mechanistic insights of guanine deaminase from Nitrosomonas europaea: role of the C-terminal loop in catalysis
Biochemistry, 52, 2013
5WI8
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CRYSTAL STRUCTURE OF MURINE 4-1BB FROM HEK293T CELLS IN P21 SPACE GROUP
Descriptor:Tumor necrosis factor receptor superfamily member 9, ALPHA-L-FUCOSE, N-ACETYL-D-GLUCOSAMINE, ...
Authors:Zajonc, D.M., Bitra, A.
Deposit date:2017-07-18
Release date:2017-12-20
Last modified:2018-10-31
Method:X-RAY DIFFRACTION (2.95 Å)
Cite:Crystal structure of murine 4-1BB and its interaction with 4-1BBL support a role for galectin-9 in 4-1BB signaling.
J. Biol. Chem., 293, 2018
5WIW
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CRYSTAL STRUCTURE OF MURINE 4-1BB N128A MUTANT FROM HEK293T CELLS IN P43 SPACE GROUP
Descriptor:Tumor necrosis factor receptor superfamily member 9, N-ACETYL-D-GLUCOSAMINE, GLYCEROL, ...
Authors:Zajonc, D.M., Bitra, A.
Deposit date:2017-07-20
Release date:2017-12-20
Last modified:2018-04-25
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Crystal structure of murine 4-1BB and its interaction with 4-1BBL support a role for galectin-9 in 4-1BB signaling.
J. Biol. Chem., 293, 2018
5WJF
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CRYSTAL STRUCTURE OF MURINE 4-1BB FROM HEK293T CELLS IN P21212 SPACE GROUP
Descriptor:Tumor necrosis factor receptor superfamily member 9, N-ACETYL-D-GLUCOSAMINE, 1,2-ETHANEDIOL
Authors:Zajonc, D.M., Doukov, T., Bitra, A.
Deposit date:2017-07-21
Release date:2017-12-20
Last modified:2018-04-25
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Crystal structure of murine 4-1BB and its interaction with 4-1BBL support a role for galectin-9 in 4-1BB signaling.
J. Biol. Chem., 293, 2018
6MIV
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CRYSTAL STRUCTURE OF THE MCD1D/XXQ (JJ300)/INKTCR TERNARY COMPLEX
Descriptor:T cell receptor alpha variable 11,T cell receptor alpha variable 11,T cell receptor alpha joining 18,Human nkt tcr alpha chain, CHIMERIC PROTEIN,Human nkt tcr alpha chain, Beta-chain,Tcell receptor chain,T cell receptor beta constant 2, ...
Authors:Zajonc, D.M., Bitra, A., Janssens, J.
Deposit date:2018-09-20
Release date:2019-01-09
Last modified:2019-02-13
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:4"-O-Alkylated alpha-Galactosylceramide Analogues as iNKT-Cell Antigens: Synthetic, Biological, and Structural Studies.
ChemMedChem, 14, 2019
6MIY
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CRYSTAL STRUCTURE OF THE MCD1D/XXA (JJ239)/INKTCR TERNARY COMPLEX
Descriptor:T cell receptor alpha variable 11,T cell receptor alpha variable 11,T cell receptor alpha joining 18,Human nkt tcr alpha chain, CHIMERIC PROTEIN, Beta-chain,T cell receptor chain,T cell receptor beta constant 2, ...
Authors:Zajonc, D.M., Bitra, A., Janssens, J.
Deposit date:2018-09-20
Release date:2019-01-09
Last modified:2019-01-16
Method:X-RAY DIFFRACTION (2.75 Å)
Cite:4"-O-Alkylated alpha-Galactosylceramide Analogues as iNKT-Cell Antigens: Synthetic, Biological, and Structural Studies.
ChemMedChem, 14, 2019
6MJ4
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CRYSTAL STRUCTURE OF MCD1D/INKTCR TERNARY COMPLEX BOUND TO GLYCOLIPID (XXW)
Descriptor:T cell receptor alpha variable 11,T cell receptor alpha variable 11,T cell receptor alpha joining 18,Human nkt tcr alpha chain, chimeric protein, Beta-chain,T cell receptor chain,T cell receptor beta constant 2, ...
Authors:Zajonc, D.M., Bitra, A., Janssens, J.
Deposit date:2018-09-20
Release date:2019-01-09
Last modified:2019-01-16
Method:X-RAY DIFFRACTION (2 Å)
Cite:4"-O-Alkylated alpha-Galactosylceramide Analogues as iNKT-Cell Antigens: Synthetic, Biological, and Structural Studies.
ChemMedChem, 14, 2019
6MJ6
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CRYSTAL STRUCTURE OF THE MCD1D/XXX (JJ166) /INKTCR TERNARY COMPLEX
Descriptor:T cell receptor alpha variable 11,T cell receptor alpha variable 11,T cell receptor alpha joining 18,Human nkt tcr alpha chain, CHIMERIC PROTEIN,Human nkt tcr alpha chain, Beta-chain,T cell receptor chain,T cell receptor beta constant 2, ...
Authors:Zajonc, D.M., Bitra, A., Janssens, J.
Deposit date:2018-09-20
Release date:2019-01-09
Last modified:2019-01-16
Method:X-RAY DIFFRACTION (2.45 Å)
Cite:4"-O-Alkylated alpha-Galactosylceramide Analogues as iNKT-Cell Antigens: Synthetic, Biological, and Structural Studies.
ChemMedChem, 14, 2019
6MJA
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CRYSTAL STRUCTURE OF THE MCD1D/XXO (JJ294) /INKTCR TERNARY COMPLEX
Descriptor:T cell receptor alpha variable 11,T cell receptor alpha variable 11,T cell receptor alpha joining 18,Human nkt tcr alpha chain, CHIMERIC PROTEIN, Beta-chain,T cell receptor chain,T cell receptor beta constant 2, ...
Authors:Zajonc, D.M., Bitra, A., Janssens, J.
Deposit date:2018-09-20
Release date:2019-01-09
Last modified:2019-01-16
Method:X-RAY DIFFRACTION (2.35 Å)
Cite:4"-O-Alkylated alpha-Galactosylceramide Analogues as iNKT-Cell Antigens: Synthetic, Biological, and Structural Studies.
ChemMedChem, 14, 2019
6MJI
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CRYSTAL STRUCTURE OF THE MCD1D/XXS (JJ304) /INKTCR TERNARY COMPLEX
Descriptor:T cell receptor alpha variable 11,T cell receptor alpha joining 18,Human nkt tcr alpha chain, CHIMERIC PROTEIN, Beta-chain,Tcell receptor chain,T cell receptor beta constant 2, ...
Authors:Zajonc, D.M., Bitra, A., Janssens, J.
Deposit date:2018-09-20
Release date:2019-01-09
Last modified:2019-01-16
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:4"-O-Alkylated alpha-Galactosylceramide Analogues as iNKT-Cell Antigens: Synthetic, Biological, and Structural Studies.
ChemMedChem, 14, 2019
6MJJ
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CRYSTAL STRUCTURE OF THE MCD1D/XXM (JJ290) /INKTCR TERNARY COMPLEX
Descriptor:T cell receptor alpha variable 11,T cell receptor alpha variable 11,T cell receptor alpha joining 18,Human nkt tcr alpha chain, CHIMERIC PROTEIN, Beta-chain,Tcell receptor chain,T cell receptor beta constant 2, ...
Authors:Zajonc, D.M., Bitra, A., Janssens, J.
Deposit date:2018-09-21
Release date:2019-01-09
Last modified:2019-01-16
Method:X-RAY DIFFRACTION (1.93 Å)
Cite:4"-O-Alkylated alpha-Galactosylceramide Analogues as iNKT-Cell Antigens: Synthetic, Biological, and Structural Studies.
ChemMedChem, 14, 2019
6MJQ
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CRYSTAL STRUCTURE OF THE MCD1D/XXP (JJ295) /INKTCR TERNARY COMPLEX
Descriptor:T cell receptor alpha variable 11,T cell receptor alpha variable 11,T cell receptor alpha joining 18,Human nkt tcr alpha chain, chimeric protein, Beta-chain,T cell receptor chain,T cell receptor beta constant 2, ...
Authors:Zajonc, D.M., Bitra, A., Janssens, J.
Deposit date:2018-09-21
Release date:2019-01-09
Last modified:2019-01-16
Method:X-RAY DIFFRACTION (3 Å)
Cite:4"-O-Alkylated alpha-Galactosylceramide Analogues as iNKT-Cell Antigens: Synthetic, Biological, and Structural Studies.
ChemMedChem, 14, 2019
6OJP
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STRUCTURE OF GLYCOLIPID ALPHA-GSA[8,6P] IN COMPLEX WITH MOUSE CD1D
Descriptor:Antigen-presenting glycoprotein CD1d1, Beta-2-microglobulin, N-ACETYL-D-GLUCOSAMINE, ...
Authors:Zajonc, D.M., Bitra, A.
Deposit date:2019-04-11
Release date:2019-08-21
Method:X-RAY DIFFRACTION (2.17 Å)
Cite:A molecular switch in mouse CD1d modulates natural killer T cell activation by alpha-galactosylsphingamides.
J.Biol.Chem., 2019
6CPR
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CRYSTAL STRUCTURE OF 4-1BBL/4-1BB COMPLEX IN C2 SPACE GROUP
Descriptor:Tumor necrosis factor ligand superfamily member 9, Tumor necrosis factor receptor superfamily member 9, GLYCEROL, ...
Authors:Aruna, B., Zajonc, D.M.
Deposit date:2018-03-14
Release date:2018-05-09
Last modified:2018-07-11
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Crystal structures of the human 4-1BB receptor bound to its ligand 4-1BBL reveal covalent receptor dimerization as a potential signaling amplifier.
J. Biol. Chem., 293, 2018
6CU0
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CRYSTAL STRUCTURE OF 4-1BBL/4-1BB (C121S) COMPLEX IN P21 SPACE GROUP
Descriptor:Tumor necrosis factor ligand superfamily member 9, Tumor necrosis factor receptor superfamily member 9, N-ACETYL-D-GLUCOSAMINE
Authors:Aruna, B., Zajonc, D.M., Doukov, T.
Deposit date:2018-03-23
Release date:2018-05-09
Last modified:2018-07-11
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Crystal structures of the human 4-1BB receptor bound to its ligand 4-1BBL reveal covalent receptor dimerization as a potential signaling amplifier.
J. Biol. Chem., 293, 2018
6D3N
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CRYSTAL STRUCTURE OF H4-1BB LIGAND
Descriptor:Tumor necrosis factor ligand superfamily member 9, GLYCEROL
Authors:Aruna, B., Zajonc, D.M., Doukov, T.
Deposit date:2018-04-16
Release date:2018-05-09
Last modified:2018-07-11
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Crystal structures of the human 4-1BB receptor bound to its ligand 4-1BBL reveal covalent receptor dimerization as a potential signaling amplifier.
J. Biol. Chem., 293, 2018
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