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1SVX
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CRYSTAL STRUCTURE OF A DESIGNED SELECTED ANKYRIN REPEAT PROTEIN IN COMPLEX WITH THE MALTOSE BINDING PROTEIN
Descriptor:Ankyrin Repeat Protein off7, Maltose-binding periplasmic protein
Authors:Binz, H.K., Amstutz, P., Kohl, A., Stumpp, M.T., Briand, C., Forrer, P., Gruetter, M.G., Plueckthun, A.
Deposit date:2004-03-30
Release date:2004-05-25
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.24 Å)
Cite:High-affinity binders selected from designed ankyrin repeat protein libraries
NAT.BIOTECHNOL., 22, 2004
2BKG
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CRYSTAL STRUCTURE OF E3_19 A DESIGNED ANKYRIN REPEAT PROTEIN
Descriptor:SYNTHETIC CONSTRUCT ANKYRIN REPEAT PROTEIN E3_19
Authors:Binz, H.K., Kohl, A., Pluckthun, A., Grutter, M.G.
Deposit date:2005-02-16
Release date:2006-06-21
Last modified:2015-10-21
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Crystal Structure of a Consensus-Designed Ankyrin Repeat Protein: Implications for Stability
Proteins: Struct., Funct., Bioinf., 65, 2006
1MJ0
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SANK E3_5: AN ARTIFICIAL ANKYRIN REPEAT PROTEIN
Descriptor:SANK E3_5 Protein, SULFATE ION, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL
Authors:Kohl, A., Binz, H.K., Forrer, P., Stumpp, M.T., Plueckthun, A., Gruetter, M.G.
Deposit date:2002-08-26
Release date:2003-01-21
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.031 Å)
Cite:Designed to be stable: Crystal structure of a consensus ankyrin repeat protein
Proc.Natl.Acad.Sci.USA, 100, 2003
2BKK
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CRYSTAL STRUCTURE OF AMINOGLYCOSIDE PHOSPHOTRANSFERASE APH(3')-IIIA IN COMPLEX WITH THE INHIBITOR AR_3A
Descriptor:AMINOGLYCOSIDE 3'-PHOSPHOTRANSFERASE, DESIGNED ANKYRIN REPEAT INHIBITOR AR_3A, ADENOSINE-5'-DIPHOSPHATE, ...
Authors:Kohl, A., Amstutz, P., Parizek, P., Binz, H.K., Briand, C., Capitani, G., Forrer, P., Pluckthun, A., Grutter, M.G.
Deposit date:2005-02-16
Release date:2005-08-09
Last modified:2016-12-21
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:Allosteric Inhibition of Aminoglycoside Phosphotransferase by a Designed Ankyrin Repeat Protein
Structure, 13, 2005
2V5Q
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CRYSTAL STRUCTURE OF WILD-TYPE PLK-1 KINASE DOMAIN IN COMPLEX WITH A SELECTIVE DARPIN
Descriptor:SERINE/THREONINE-PROTEIN KINASE PLK1, DESIGN ANKYRIN REPEAT PROTEIN
Authors:Bandeiras, T.M., Hillig, R.C., Matias, P.M., Eberspaecher, U., Fanghaenel, J., Thomaz, M., Miranda, S., Crusius, K., Puetter, V., Amstutz, P., Gulotti-Georgieva, M., Binz, H.K., Holz, C., Schmitz, A.A.P., Lang, C., Donner, P., Egner, U., Carrondo, M.A., Mueller-Tiemann, B.
Deposit date:2007-07-08
Release date:2008-04-01
Last modified:2019-02-20
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structure of wild-type Plk-1 kinase domain in complex with a selective DARPin.
Acta Crystallogr. D Biol. Crystallogr., 64, 2008
5OYJ
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CRYSTAL STRUCTURE OF VEGFR-2 DOMAINS 4-5 IN COMPLEX WITH DARPIN D4B
Descriptor:DARPin D4b, Vascular endothelial growth factor receptor 2, CALCIUM ION, ...
Authors:Piscitelli, C.L., Thieltges, K.M., Markovic-Mueller, S., Binz, H.K., Ballmer-Hofer, K.
Deposit date:2017-09-10
Release date:2018-03-14
Last modified:2018-07-25
Method:X-RAY DIFFRACTION (2.38 Å)
Cite:Characterization of a drug-targetable allosteric site regulating vascular endothelial growth factor signaling.
Angiogenesis, 21, 2018
2P2C
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INHIBITION OF CASPASE-2 BY A DESIGNED ANKYRIN REPEAT PROTEIN (DARPIN)
Descriptor:Caspase-2
Authors:Roschitzki Voser, H., Briand, C., Capitani, G., Gruetter, M.G.
Deposit date:2007-03-07
Release date:2007-05-22
Last modified:2018-01-24
Method:X-RAY DIFFRACTION (3.24 Å)
Cite:Inhibition of Caspase-2 by a Designed Ankyrin Repeat Protein: Specificity, Structure, and Inhibition Mechanism.
Structure, 15, 2007