Author results

6EC6
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RUMINOCOCCUS GNAVUS BETA-GLUCURONIDASE
Descriptor:Beta-glucuronidase, GLYCEROL, CHLORIDE ION
Authors:Biernat, K.A., Redinbo, M.R.
Deposit date:2018-08-07
Release date:2019-02-13
Method:X-RAY DIFFRACTION (2.85 Å)
Cite:Structure, function, and inhibition of drug reactivating human gut microbial beta-glucuronidases.
Sci Rep, 9, 2019
6ECA
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LACTOBACILLUS RHAMNOSUS BETA-GLUCURONIDASE
Descriptor:Beta-glucuronidase, GLYCEROL, CHLORIDE ION
Authors:Biernat, K.A., Pellock, S.J., Bhatt, A.P., Bivins, M.M., Walton, W.G., Tran, B.N.T., Wei, L., Snider, M.C., Cesmat, A.P., Tripathy, A., Erie, D.A., Redinbo, M.R.R.
Deposit date:2018-08-07
Release date:2019-02-13
Method:X-RAY DIFFRACTION (2.853 Å)
Cite:Structure, function, and inhibition of drug reactivating human gut microbial beta-glucuronidases.
Sci Rep, 9, 2019
6ED1
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BACTEROIDES DOREI BETA-GLUCURONIDASE
Descriptor:Glycosyl hydrolase family 2, sugar binding domain protein, SODIUM ION
Authors:Biernat, K.A., Redinbo, M.R.
Deposit date:2018-08-08
Release date:2019-02-13
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Structure, function, and inhibition of drug reactivating human gut microbial beta-glucuronidases.
Sci Rep, 9, 2019
6ED2
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FAECALIBACTERIUM PRAUSNITZII BETA-GLUCURONIDASE
Descriptor:Glycosyl hydrolase family 2, TIM barrel domain protein, GLYCEROL, ...
Authors:Pellock, S.J., Biernat, K.A., Redinbo, M.R.
Deposit date:2018-08-08
Release date:2019-02-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structure, function, and inhibition of drug reactivating human gut microbial beta-glucuronidases.
Sci Rep, 9, 2019
5FF5
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CRYSTAL STRUCTURE OF SEMET PAAA
Descriptor:PaaA, SULFATE ION, GLYCEROL, ...
Authors:Biernat, K.B., Redinbo, M.R.
Deposit date:2015-12-17
Release date:2016-04-27
Last modified:2016-05-18
Method:X-RAY DIFFRACTION (2.933 Å)
Cite:Post-translational Claisen Condensation and Decarboxylation en Route to the Bicyclic Core of Pantocin A.
J.Am.Chem.Soc., 138, 2016
4JKK
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CRYSTAL STRUCTURE OF STREPTOCOCCUS AGALACTIAE BETA-GLUCURONIDASE IN SPACE GROUP I222
Descriptor:Beta-glucuronidase, MAGNESIUM ION
Authors:Wallace, B.D., Redinbo, M.R.
Deposit date:2013-03-09
Release date:2014-09-17
Last modified:2015-10-21
Method:X-RAY DIFFRACTION (2.59 Å)
Cite:Structure and Inhibition of Microbiome beta-Glucuronidases Essential to the Alleviation of Cancer Drug Toxicity.
Chem.Biol., 22, 2015
4JKL
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CRYSTAL STRUCTURE OF STREPTOCOCCUS AGALACTIAE BETA-GLUCURONIDASE IN SPACE GROUP P21212
Descriptor:Beta-glucuronidase, MAGNESIUM ION
Authors:Wallace, B.D., Redinbo, M.R.
Deposit date:2013-03-09
Release date:2014-09-17
Last modified:2015-10-21
Method:X-RAY DIFFRACTION (2.288 Å)
Cite:Structure and Inhibition of Microbiome beta-Glucuronidases Essential to the Alleviation of Cancer Drug Toxicity.
Chem.Biol., 22, 2015
4JKM
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CRYSTAL STRUCTURE OF CLOSTRIDIUM PERFRINGENS BETA-GLUCURONIDASE
Descriptor:Beta-glucuronidase, Maltose-binding periplasmic protein
Authors:Wallace, B.D., Redinbo, M.R.
Deposit date:2013-03-09
Release date:2014-09-17
Last modified:2015-10-21
Method:X-RAY DIFFRACTION (2.263 Å)
Cite:Structure and Inhibition of Microbiome beta-Glucuronidases Essential to the Alleviation of Cancer Drug Toxicity.
Chem.Biol., 22, 2015
5CZK
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STRUCTURE OF E. COLI BETA-GLUCURONIDASE BOUND WITH A NOVEL, POTENT INHIBITOR 1-((6,8-DIMETHYL-2-OXO-1,2-DIHYDROQUINOLIN-3-YL)METHYL)-1-(2-HYDROXYETHYL)-3-(4-HYDROXYPHENYL)THIOUREA
Descriptor:Beta-glucuronidase, 1-[(6,8-dimethyl-2-oxo-1,2-dihydroquinolin-3-yl)methyl]-1-(2-hydroxyethyl)-3-(4-hydroxyphenyl)thiourea
Authors:Roberts, A.R., Wallace, B.R., Redinbo, M.R.
Deposit date:2015-07-31
Release date:2015-10-14
Last modified:2017-09-06
Method:X-RAY DIFFRACTION (2.39 Å)
Cite:Structure and Inhibition of Microbiome beta-Glucuronidases Essential to the Alleviation of Cancer Drug Toxicity.
Chem.Biol., 22, 2015
5UJ6
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CRYSTAL STRUCTURE OF BACTEROIDES UNIFORMIS BETA-GLUCURONIDASE
Descriptor:Glycosyl hydrolases family 2, sugar binding domain protein, GLYCEROL, ...
Authors:Walton, W.G., Redinbo, M.R.
Deposit date:2017-01-17
Release date:2017-06-28
Last modified:2017-09-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:An Atlas of beta-Glucuronidases in the Human Intestinal Microbiome.
Structure, 25, 2017
6BJQ
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EUBACTERIUM ELIGENS BETA-GLUCURONIDASE BOUND TO GLUCURONIC ACID
Descriptor:Glycoside Hydrolase Family 2 candidate b-glucuronidase, BETA-D-GLUCOPYRANURONIC ACID
Authors:Pellock, S.J., Walton, W.G., Redinbo, M.R.
Deposit date:2017-11-06
Release date:2018-07-25
Last modified:2019-02-20
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Gut Microbial beta-Glucuronidase Inhibition via Catalytic Cycle Interception.
ACS Cent Sci, 4, 2018
6BJW
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EUBACTERIUM ELIGENS BETA-GLUCURONIDASE
Descriptor:Glycoside Hydrolase Family 2 candidate b-glucuronidase
Authors:Pellock, S.J., Walton, W.G., Redinbo, M.R.
Deposit date:2017-11-07
Release date:2018-07-25
Last modified:2019-02-20
Method:X-RAY DIFFRACTION (3 Å)
Cite:Gut Microbial beta-Glucuronidase Inhibition via Catalytic Cycle Interception.
ACS Cent Sci, 4, 2018
6BO6
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EUBACTERIUM ELIGENS BETA-GLUCURONIDASE BOUND TO UNC4917 GLUCURONIC ACID CONJUGATE
Descriptor:Glycoside Hydrolase Family 2 candidate b-glucuronidase, 4-(4-beta-D-glucopyranuronosylpiperazin-1-yl)-2,7-bis(methylamino)pyrido[3',2':4,5]thieno[3,2-d]pyrimidine
Authors:Pellock, S.J., Walton, W.G., Redinbo, M.R.
Deposit date:2017-11-18
Release date:2018-07-25
Last modified:2019-02-20
Method:X-RAY DIFFRACTION (2.801 Å)
Cite:Gut Microbial beta-Glucuronidase Inhibition via Catalytic Cycle Interception.
ACS Cent Sci, 4, 2018
6D1N
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APO STRUCTURE OF BACTEROIDES UNIFORMIS BETA-GLUCURONIDASE 1
Descriptor:Beta-galactosidase/beta-glucuronidase, GLYCEROL, CHLORIDE ION
Authors:Walton, W.G., Pellock, S.J., Redinbo, M.R.
Deposit date:2018-04-12
Release date:2018-10-17
Last modified:2018-12-19
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Three structurally and functionally distinct beta-glucuronidases from the human gut microbeBacteroides uniformis.
J. Biol. Chem., 293, 2018
6D1P
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APO STRUCTURE OF BACTEROIDES UNIFORMIS BETA-GLUCURONIDASE 3
Descriptor:Glycosyl hydrolases family 2, sugar binding domain protein, SODIUM ION, ...
Authors:Walton, W.G., Pellock, S.J., Redinbo, M.R.
Deposit date:2018-04-12
Release date:2018-10-17
Last modified:2018-12-19
Method:X-RAY DIFFRACTION (2.35 Å)
Cite:Three structurally and functionally distinct beta-glucuronidases from the human gut microbeBacteroides uniformis.
J. Biol. Chem., 293, 2018
6D41
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BACTERIODES UNIFORMIS BETA-GLUCURONIDASE 1 BOUND TO D-GLUCARO-1,5-LACTONE
Descriptor:Beta-galactosidase/beta-glucuronidase, GLYCEROL, CHLORIDE ION, ...
Authors:Walton, W.G., Pellock, S.J., Redinbo, M.R.
Deposit date:2018-04-17
Release date:2018-10-17
Last modified:2018-12-19
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Three structurally and functionally distinct beta-glucuronidases from the human gut microbeBacteroides uniformis.
J. Biol. Chem., 293, 2018
6D4O
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EUBACTERIUM ELIGENS BETA-GLUCURONIDASE BOUND TO AN AMOXAPINE-GLUCURONIDE CONJUGATE
Descriptor:Beta-glucuronidase, (5aR,9aR)-2-chloro-11-(4-beta-D-glucopyranuronosylpiperazin-1-yl)-5a,6,9,9a-tetrahydrodibenzo[b,f][1,4]oxazepine, CHLORIDE ION, ...
Authors:Pellock, S.J., Walton, W.G., Redinbo, M.R.
Deposit date:2018-04-18
Release date:2018-07-25
Last modified:2018-08-22
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Gut Microbial beta-Glucuronidase Inhibition via Catalytic Cycle Interception.
ACS Cent Sci, 4, 2018
6D50
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BACTEROIDES UNIFORMS BETA-GLUCURONIDASE 2 BOUND TO D-GLUCARO-1,5-LACTONE
Descriptor:Glycosyl hydrolases family 2, sugar binding domain protein, CALCIUM ION, ...
Authors:Walton, W.G., Pellock, S.J., Redinbo, M.R.
Deposit date:2018-04-19
Release date:2018-10-17
Last modified:2018-12-19
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Three structurally and functionally distinct beta-glucuronidases from the human gut microbeBacteroides uniformis.
J. Biol. Chem., 293, 2018
6D6W
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BACTEROIDES UNIFORMIS BETA-GLUCURONIDASE 1 BOUND TO GLUCURONATE
Descriptor:Beta-galactosidase/beta-glucuronidase, D-GLUCURONIC ACID, GLYCEROL, ...
Authors:Walton, W.G., Pellock, S.J., Redinbo, M.R.
Deposit date:2018-04-23
Release date:2018-10-17
Last modified:2018-12-19
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Three structurally and functionally distinct beta-glucuronidases from the human gut microbeBacteroides uniformis.
J. Biol. Chem., 293, 2018
6D7F
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BACTEROIDES UNIFORMIS BETA-GLUCURONIDASE 1 BOUND TO THIOPHENYL-BETA-D-GLUCURONIDE
Descriptor:Beta-galactosidase/beta-glucuronidase, phenyl 1-thio-beta-D-glucopyranosiduronic acid, CHLORIDE ION, ...
Authors:Walton, W.G., Pellock, S.J., Redinbo, M.R.
Deposit date:2018-04-24
Release date:2018-10-17
Last modified:2018-12-19
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Three structurally and functionally distinct beta-glucuronidases from the human gut microbeBacteroides uniformis.
J. Biol. Chem., 293, 2018
6D89
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BACTEROIDES UNIFORMIS BETA-GLUCURONIDASE 1 WITH N-TERMINAL LOOP DELETION
Descriptor:Beta-galactosidase/beta-glucuronidase, CITRIC ACID, CHLORIDE ION
Authors:Walton, W.G., Pellock, S.J., Redinbo, M.R.
Deposit date:2018-04-26
Release date:2018-10-17
Last modified:2018-12-19
Method:X-RAY DIFFRACTION (2 Å)
Cite:Three structurally and functionally distinct beta-glucuronidases from the human gut microbeBacteroides uniformis.
J. Biol. Chem., 293, 2018
6D8G
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D341A D367A CALCIUM BINDING MUTANT OF BACTEROIDES UNIFORMIS BETA-GLUCURONIDASE 2
Descriptor:Glycosyl hydrolases family 2, sugar binding domain protein, SODIUM ION
Authors:Walton, W.G., Pellock, S.J., Redinbo, M.R.
Deposit date:2018-04-26
Release date:2018-10-17
Last modified:2018-12-19
Method:X-RAY DIFFRACTION (3 Å)
Cite:Three structurally and functionally distinct beta-glucuronidases from the human gut microbeBacteroides uniformis.
J. Biol. Chem., 293, 2018
6D8K
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BACTEROIDES MULTIPLE SPECIES BETA-GLUCURONIDASE
Descriptor:Glycosyl hydrolase family 2, sugar binding domain protein
Authors:Walton, W.G., Pellock, S.J., Redinbo, M.R.
Deposit date:2018-04-26
Release date:2018-10-17
Last modified:2018-12-19
Method:X-RAY DIFFRACTION (2.65 Å)
Cite:Three structurally and functionally distinct beta-glucuronidases from the human gut microbeBacteroides uniformis.
J. Biol. Chem., 293, 2018