Author results

3G7N
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CRYSTAL STRUCTURE OF A TRIACYLGLYCEROL LIPASE FROM PENICILLIUM EXPANSUM AT 1.3
Descriptor:Lipase, SULFATE ION, DI(HYDROXYETHYL)ETHER, ...
Authors:Bian, C.B., Yuan, C., Chen, L.Q., Edward, J.M., Lin, L., Jiang, L.G., Huang, Z.X., Huang, M.D.
Deposit date:2009-02-10
Release date:2010-02-23
Last modified:2017-11-01
Method:X-RAY DIFFRACTION (1.3 Å)
Cite:Crystal structure of a triacylglycerol lipase from Penicillium expansum at 1.3 A determined by sulfur SAD
Proteins, 78, 2010
3IHO
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THE C-TERMINAL GLYCOSYLASE DOMAIN OF HUMAN MBD4
Descriptor:Methyl-CpG-binding domain protein 4
Authors:Amaya, M.F., Xu, C., Bian, C.B., Bountra, C., Weigelt, J., Arrowsmith, C.H., Edwards, A.M., Bochkarev, A., Min, J., Structural Genomics Consortium (SGC)
Deposit date:2009-07-30
Release date:2009-08-25
Last modified:2017-11-01
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:The C-terminal glycosylase domain of human MBD4
To be Published
3K26
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COMPLEX STRUCTURE OF EED AND TRIMETHYLATED H3K4
Descriptor:Polycomb protein EED, HISTONE PEPTIDE
Authors:Bian, C.B., Xu, C., Qiu, W., Bountra, C., Weigelt, J., Arrowsmith, C.H., Edwards, A.M., Bochkarev, A., Min, J., Structural Genomics Consortium (SGC)
Deposit date:2009-09-29
Release date:2009-12-15
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.58 Å)
Cite:Binding of different histone marks differentially regulates the activity and specificity of polycomb repressive complex 2 (PRC2).
Proc.Natl.Acad.Sci.USA, 107, 2010
3K27
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COMPLEX STRUCTURE OF EED AND TRIMETHYLATED H3K9
Descriptor:Polycomb protein EED, HISTONE PEPTIDE
Authors:Bian, C.B., Xu, C., Qiu, W., Bountra, C., Weigelt, J., Arrowsmith, C.H., Edwards, A.M., Bochkarev, A., Min, J., Structural Genomics Consortium (SGC)
Deposit date:2009-09-29
Release date:2009-12-15
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.76 Å)
Cite:Binding of different histone marks differentially regulates the activity and specificity of polycomb repressive complex 2 (PRC2).
Proc.Natl.Acad.Sci.USA, 107, 2010
3LX7
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CRYSTAL STRUCTURE OF A NOVEL TUDOR DOMAIN-CONTAINING PROTEIN SGF29
Descriptor:SAGA-associated factor 29 homolog, SULFATE ION, UNKNOWN ATOM OR ION
Authors:Bian, C.B., Xu, C., Tempel, W., Lam, R., Bountra, C., Arrowsmith, C.H., Weigelt, J., Edwards, A.M., Bochkarev, A., Min, J.
Deposit date:2010-02-24
Release date:2010-05-05
Last modified:2011-08-03
Method:X-RAY DIFFRACTION (1.78 Å)
Cite:Sgf29 binds histone H3K4me2/3 and is required for SAGA complex recruitment and histone H3 acetylation.
Embo J., 30, 2011
3MET
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CRYSTAL STRUCTURE OF SGF29 IN COMPLEX WITH H3K4ME2
Descriptor:SAGA-associated factor 29 homolog, Histone H3, UNKNOWN ATOM OR ION, ...
Authors:Bian, C.B., Xu, C., Lam, R., Bountra, C., Arrowsmith, C.H., Weigelt, J., Edwards, A.M., Bochkarev, A., Min, J., Structural Genomics Consortium (SGC)
Deposit date:2010-03-31
Release date:2010-04-28
Last modified:2011-08-03
Method:X-RAY DIFFRACTION (2 Å)
Cite:Sgf29 binds histone H3K4me2/3 and is required for SAGA complex recruitment and histone H3 acetylation.
Embo J., 30, 2011
3MEU
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CRYSTAL STRUCTURE OF SGF29 IN COMPLEX WITH H3R2ME2SK4ME3
Descriptor:SAGA-associated factor 29 homolog, Histone H3, SULFATE ION
Authors:Bian, C.B., Xu, C., Bountra, C., Arrowsmith, C.H., Weigelt, J., Edwards, A.M., Bochkarev, A., Min, J., Structural Genomics Consortium (SGC)
Deposit date:2010-03-31
Release date:2010-04-28
Last modified:2011-08-03
Method:X-RAY DIFFRACTION (1.28 Å)
Cite:Sgf29 binds histone H3K4me2/3 and is required for SAGA complex recruitment and histone H3 acetylation.
Embo J., 30, 2011
3MEV
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CRYSTAL STRUCTURE OF SGF29 IN COMPLEX WITH R2AK4ME3
Descriptor:SAGA-associated factor 29 homolog, Histone H3, SULFATE ION, ...
Authors:Bian, C.B., Xu, C., Lam, R., Bountra, C., Arrowsmith, C.H., Weigelt, J., Edwards, A.M., Bochkarev, A., Min, J., Structural Genomics Consortium (SGC)
Deposit date:2010-03-31
Release date:2010-04-28
Last modified:2012-05-09
Method:X-RAY DIFFRACTION (1.83 Å)
Cite:Sgf29 binds histone H3K4me2/3 and is required for SAGA complex recruitment and histone H3 acetylation.
Embo J., 30, 2011
3O7A
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CRYSTAL STRUCTURE OF PHF13 IN COMPLEX WITH H3K4ME3
Descriptor:PHD finger protein 13 variant, H3K4ME3 HISTONE 11MER-PEPTIDE, GLYCEROL, ...
Authors:Bian, C.B., Lam, R., Xu, C., Bountra, C., Arrowsmith, C.H., Weigelt, J., Edwards, A.M., Bochkarev, A., Min, J., Structural Genomics Consortium (SGC)
Deposit date:2010-07-30
Release date:2010-10-06
Last modified:2016-06-22
Method:X-RAY DIFFRACTION (1.67 Å)
Cite:PHF13 is a molecular reader and transcriptional co-regulator of H3K4me2/3.
Elife, 5, 2016
3JPX
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EED: A NOVEL HISTONE TRIMETHYLLYSINE BINDER WITHIN THE EED-EZH2 POLYCOMB COMPLEX
Descriptor:Polycomb protein EED, HISTONE PEPTIDE
Authors:Xu, C., Bian, C.B., Bountra, C., Weigelt, J., Arrowsmith, C.H., Edwards, A.M., Bochkarev, A., Min, J., Structural Genomics Consortium (SGC)
Deposit date:2009-09-04
Release date:2009-10-20
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:Binding of different histone marks differentially regulates the activity and specificity of polycomb repressive complex 2 (PRC2).
Proc.Natl.Acad.Sci.USA, 107, 2010
3JZG
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STRUCTURE OF EED IN COMPLEX WITH H3K27ME3
Descriptor:Polycomb protein EED, HISTONE PEPTIDE
Authors:Xu, C., Bian, C.B., Bountra, C., Weigelt, J., Arrowsmith, C.H., Edwards, A.M., Bochkarev, A., Min, J., Structural Genomics Consortium (SGC)
Deposit date:2009-09-23
Release date:2009-12-15
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Binding of different histone marks differentially regulates the activity and specificity of polycomb repressive complex 2 (PRC2).
Proc.Natl.Acad.Sci.USA, 107, 2010
3JZH
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EED-H3K79ME3
Descriptor:Polycomb protein EED, HISTONE PEPTIDE
Authors:Xu, C., Bian, C.B., Bountra, C., Weigelt, J., Arrowsmith, C.H., Edwards, A.M., Bochkarev, A., Min, J., Structural Genomics Consortium (SGC)
Deposit date:2009-09-23
Release date:2009-12-15
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:Binding of different histone marks differentially regulates the activity and specificity of polycomb repressive complex 2 (PRC2).
Proc.Natl.Acad.Sci.USA, 107, 2010
3JZN
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STRUCTURE OF EED IN APO FORM
Descriptor:Polycomb protein EED
Authors:Xu, C., Bian, C.B., Ouyang, H., Qiu, W., MacKenzie, F., Min, J., Structural Genomics Consortium (SGC)
Deposit date:2009-09-23
Release date:2009-12-15
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Binding of different histone marks differentially regulates the activity and specificity of polycomb repressive complex 2 (PRC2).
Proc.Natl.Acad.Sci.USA, 107, 2010
3KUF
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THE CRYSTAL STRUCTURE OF THE TUDOR DOMAINS FROM FXR1
Descriptor:Fragile X mental retardation syndrome-related protein 1, 2,3-DIHYDROXY-1,4-DITHIOBUTANE, GLYCEROL
Authors:Bian, C., Guo, Y.H., Adams-Cioaba, M.A., Mackenzie, F., Kozieradzki, I., Bountra, C., Weigelt, J., Arrowsmith, C.H., Edwards, A.M., Bochkarev, A., Min, J., Structural Genomics Consortium (SGC)
Deposit date:2009-11-27
Release date:2010-01-05
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Crystal structure of the Tudor domains from Fragile X mental retardation syndrome-related protein 1
To be Published
3MEW
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CRYSTAL STRUCTURE OF NOVEL TUDOR DOMAIN-CONTAINING PROTEIN SGF29
Descriptor:SAGA-associated factor 29 homolog
Authors:Xu, C., Bian, C.B., Lam, R., Bountra, C., Arrowsmith, C.H., Weigelt, J., Edwards, A.M., Bochkarev, A., Min, J., Structural Genomics Consortium (SGC)
Deposit date:2010-03-31
Release date:2010-04-28
Last modified:2011-08-03
Method:X-RAY DIFFRACTION (1.92 Å)
Cite:Sgf29 binds histone H3K4me2/3 and is required for SAGA complex recruitment and histone H3 acetylation.
Embo J., 30, 2011
3O70
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PHD-TYPE ZINC FINGER OF HUMAN PHD FINGER PROTEIN 13
Descriptor:PHD finger protein 13, GLYCEROL, ZINC ION
Authors:Lam, R., Bian, C.B., Xu, C., Kania, J., Bountra, C., Weigelt, J., Arrowsmith, C.H., Edwards, A.M., Bochkarev, A., Min, J., Structural Genomics Consortium (SGC)
Deposit date:2010-07-29
Release date:2010-09-29
Last modified:2017-11-08
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:PHF13 is a molecular reader and transcriptional co-regulator of H3K4me2/3.
Elife, 5, 2016
3O8V
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CRYSTAL STRUCTURE OF THE TUDOR DOMAINS FROM FXR1
Descriptor:Fragile X mental retardation syndrome-related protein 1
Authors:Lam, R., Guo, Y.H., Adams-Cioaba, M., Bian, C.B., Mackenzie, F., Bountra, C., Weigelt, J., Arrowsmith, C.H., Edwards, A.M., Bochkarev, A., Min, J., Structural Genomics Consortium (SGC)
Deposit date:2010-08-03
Release date:2010-08-18
Last modified:2017-11-08
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structural Studies of the Tandem Tudor Domains of Fragile X Mental Retardation Related Proteins FXR1 and FXR2.
Plos One, 5, 2010
3OMC
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STRUCTURE OF HUMAN SND1 EXTENDED TUDOR DOMAIN IN COMPLEX WITH THE SYMMETRICALLY DIMETHYLATED ARGININE PIWIL1 PEPTIDE R4ME2S
Descriptor:Staphylococcal nuclease domain-containing protein 1, SYNTHETIC PEPTIDE, CHLORIDE ION
Authors:Lam, R., Liu, K., Guo, Y.H., Bian, C.B., Xu, C., MacKenzie, F., Bountra, C., Weigelt, J., Arrowsmith, C.H., Edwards, A.M., Bochkarev, A., Min, J., Structural Genomics Consortium (SGC)
Deposit date:2010-08-26
Release date:2010-09-15
Last modified:2017-11-15
Method:X-RAY DIFFRACTION (1.77 Å)
Cite:Structural basis for recognition of arginine methylated Piwi proteins by the extended Tudor domain.
Proc.Natl.Acad.Sci.USA, 107, 2010
3OMG
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STRUCTURE OF HUMAN SND1 EXTENDED TUDOR DOMAIN IN COMPLEX WITH THE SYMMETRICALLY DIMETHYLATED ARGININE PIWIL1 PEPTIDE R14ME2S
Descriptor:Staphylococcal nuclease domain-containing protein 1, dimethylated arginine peptide R14me2s
Authors:Lam, R., Liu, K., Guo, Y.H., Bian, C.B., Xu, C., MacKenzie, F., Bountra, C., Weigelt, J., Arrowsmith, C.H., Edwards, A.M., Bochkarev, A., Min, J., Structural Genomics Consortium (SGC)
Deposit date:2010-08-26
Release date:2010-09-08
Last modified:2017-11-08
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Structural basis for recognition of arginine methylated Piwi proteins by the extended Tudor domain.
Proc.Natl.Acad.Sci.USA, 107, 2010
3PMT
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CRYSTAL STRUCTURE OF THE TUDOR DOMAIN OF HUMAN TUDOR DOMAIN-CONTAINING PROTEIN 3
Descriptor:Tudor domain-containing protein 3, TETRAETHYLENE GLYCOL
Authors:Lam, R., Bian, C.B., Guo, Y.H., Xu, C., Kania, J., Bountra, C., Weigelt, J., Arrowsmith, C.H., Edwards, A.M., Bochkarev, A., Min, J., Structural Genomics Consortium (SGC)
Deposit date:2010-11-18
Release date:2010-12-01
Last modified:2017-11-08
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Crystal Structure of TDRD3 and Methyl-Arginine Binding Characterization of TDRD3, SMN and SPF30.
Plos One, 7, 2012
3QMB
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STRUCTURAL BASIS OF SELECTIVE BINDING OF NONMETHYLATED CPG ISLANDS BY THE CXXC DOMAIN OF CFP1
Descriptor:CpG-binding protein, 5'-D(*GP*CP*CP*AP*CP*CP*GP*GP*TP*GP*GP*C)-3', ZINC ION, ...
Authors:Lam, R., Xu, C., Bian, C.B., Kania, J., Bountra, C., Weigelt, J., Arrowsmith, C.H., Edwards, A.M., Bochkarev, A., Min, J., Structural Genomics Consortium (SGC)
Deposit date:2011-02-04
Release date:2011-02-23
Last modified:2017-11-08
Method:X-RAY DIFFRACTION (2.06 Å)
Cite:The structural basis for selective binding of non-methylated CpG islands by the CFP1 CXXC domain.
Nat Commun, 2, 2011
3QMC
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STRUCTURAL BASIS OF SELECTIVE BINDING OF NONMETHYLATED CPG ISLANDS BY THE CXXC DOMAIN OF CFP1
Descriptor:CpG-binding protein, 5'-D(*GP*CP*CP*AP*CP*CP*GP*CP*TP*GP*GP*C)-3', 5'-D(*GP*CP*CP*AP*GP*CP*GP*GP*TP*GP*GP*C)-3', ...
Authors:Lam, R., Xu, C., Bian, C.B., Kania, J., Bountra, C., Weigelt, J., Arrowsmith, C.H., Edwards, A.M., Bochkarev, A., Min, J., Structural Genomics Consortium (SGC)
Deposit date:2011-02-04
Release date:2011-02-23
Last modified:2017-11-08
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:The structural basis for selective binding of non-methylated CpG islands by the CFP1 CXXC domain.
Nat Commun, 2, 2011
3QMD
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STRUCTURAL BASIS OF SELECTIVE BINDING OF NONMETHYLATED CPG ISLANDS BY THE CXXC DOMAIN OF CFP1
Descriptor:CpG-binding protein, DNA (5'-D(*GP*CP*CP*AP*AP*CP*GP*AP*TP*GP*GP*C)-3'), DNA (5'-D(*GP*CP*CP*AP*TP*CP*GP*TP*TP*GP*GP*C)-3'), ...
Authors:Lam, R., Xu, C., Bian, C.B., Kania, J., Bountra, C., Weigelt, J., Arrowsmith, C.H., Edwards, A.M., Bochkarev, A., Min, J., Structural Genomics Consortium (SGC)
Deposit date:2011-02-04
Release date:2011-02-23
Last modified:2017-11-08
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:The structural basis for selective binding of non-methylated CpG islands by the CFP1 CXXC domain.
Nat Commun, 2, 2011
3SO8
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CRYSTAL STRUCTURE OF ANKRA
Descriptor:Ankyrin repeat family A protein 2
Authors:Xu, C., Bochkarev, A., Bian, C.B., Min, J., Structural Genomics Consortium (SGC)
Deposit date:2011-06-30
Release date:2011-10-05
Last modified:2018-01-24
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Sequence-Specific Recognition of a PxLPxI/L Motif by an Ankyrin Repeat Tumbler Lock.
Sci.Signal., 5, 2012
3TYY
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CRYSTAL STRUCTURE OF HUMAN LAMIN-B1 COIL 2 SEGMENT
Descriptor:Lamin-B1
Authors:Lam, R., Xu, C., Bian, C.B., Mackenzie, F., Walker, J.R., Bountra, C., Weigelt, J., Arrowsmith, C.H., Edwards, A.M., Bochkarev, A., Min, J., Structural Genomics Consortium (SGC)
Deposit date:2011-09-26
Release date:2011-10-05
Last modified:2017-11-08
Method:X-RAY DIFFRACTION (2.399 Å)
Cite:Crystal structures of the coil 2B fragment and the globular tail domain of human lamin B1.
Febs Lett., 586, 2012
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