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Crystal structure of a Fab binding to extracellular domain 5 of Cadherin-6
Descriptor:	2-acetamido-2-deoxy-alpha-D-galactopyranose, Cadherin-6, SUCCINIC ACID, ...
Authors:	Zhu, X, Bialucha, C.U, London, A, Clark, K, Hu, T.
Deposit date:	2017-04-04
Release date:	2017-06-07
Last modified:	2020-07-29
Method:	X-RAY DIFFRACTION (2.34 Å)
Cite:	Discovery and Optimization of HKT288, a Cadherin-6-Targeting ADC for the Treatment of Ovarian and Renal Cancers. Cancer Discov, 7, 2017

HER3 extracellular domain in complex with Fab fragment of MOR09825
Descriptor:	2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, MOR09825 Fab fragment heavy chain, ...
Authors:	Sprague, E.R.
Deposit date:	2014-03-15
Release date:	2014-04-16
Last modified:	2023-09-27
Method:	X-RAY DIFFRACTION (3.4 Å)
Cite:	An antibody that locks HER3 in the inactive conformation inhibits tumor growth driven by HER2 or neuregulin. Cancer Res., 73, 2013