Author results

2KJD
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SOLUTION STRUCTURE OF EXTENDED PDZ2 DOMAIN FROM NHERF1 (150-270)
Descriptor:Sodium/hydrogen exchange regulatory cofactor NHE-RF1
Authors:Bhattacharya, S., Cowburn, D., Bu, Z.
Deposit date:2009-05-27
Release date:2009-12-29
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:A dynamic intramolecular conformational switch autoregulates the scaffolding protein NHERF1
To be Published
2KRG
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SOLUTION STRUCTURE OF HUMAN SODIUM/ HYDROGEN EXCHANGE REGULATORY FACTOR 1(150-358)
Descriptor:Na(+)/H(+) exchange regulatory cofactor NHE-RF1
Authors:Bhattacharya, S., Dai, Z., Li, J., Baxter, S., Callaway, D.J.E., Cowburn, D., Bu, Z.
Deposit date:2009-12-17
Release date:2009-12-29
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:A conformational switch in the sodium/ hydrogen exchange regulatory factor 1(NHERF1) controls autoinhibition and complex formation.
J.Biol.Chem., 2010
2NXP
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STRUCTURE OF NTD2 DOMAIN OF THE HUMAN TAF5 SUBUNIT OF TFIID
Descriptor:Transcription initiation factor TFIID subunit 5, CALCIUM ION
Authors:Bhattacharya, S., Takada, S., Jacobson, R.H.
Deposit date:2006-11-17
Release date:2007-01-09
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.17 Å)
Cite:Structural analysis and dimerization potential of the human TAF5 subunit of TFIID.
Proc.Natl.Acad.Sci.Usa, 104, 2007
1PSB
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SOLUTION STRUCTURE OF CALCIUM LOADED S100B COMPLEXED TO A PEPTIDE FROM N-TERMINAL REGULATORY DOMAIN OF NDR KINASE.
Descriptor:S-100 protein, beta chain, Ndr Ser/Thr kinase-like protein
Authors:Bhattacharya, S., Large, E., Heizmann, C.W., Hemmings, B., Chazin, W.J.
Deposit date:2003-06-21
Release date:2003-12-16
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Structure of the Ca(2+)/S100B/NDR Kinase Peptide Complex: Insights into S100 Target Specificity and Activation of the Kinase.
Biochemistry, 42, 2003
1YSM
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NMR STRUCTURE OF N-TERMINAL DOMAIN (RESIDUES 1-77) OF SIAH-INTERACTING PROTEIN.
Descriptor:Calcyclin-binding protein
Authors:Bhattacharya, S., Lee, Y.T., Michowski, W., Jastrzebska, B., Filipek, A., Kuznicki, J., Chazin, W.J.
Deposit date:2005-02-08
Release date:2005-07-26
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:The Modular Structure of SIP Facilitates Its Role in Stabilizing Multiprotein Assemblies.
Biochemistry, 44, 2005
2L6E
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NMR STRUCTURE OF THE MONOMERIC MUTANT C-TERMINAL DOMAIN OF HIV-1 CAPSID IN COMPLEX WITH STAPLED PEPTIDE INHIBITOR
Descriptor:Capsid protein p24, NYAD-13 stapled peptide inhibitor
Authors:Bhattacharya, S., Zhang, H., Debnath, A.K., Cowburn, D.
Deposit date:2010-11-18
Release date:2010-12-29
Last modified:2012-12-12
Method:SOLUTION NMR
Cite:Solution structure of a hydrocarbon stapled peptide inhibitor in complex with monomeric C-terminal domain of HIV-1 capsid.
J.Biol.Chem., 283, 2008
2M0T
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STRUCTURAL CHARACTERIZATION OF THE EXTENDED PDZ1 DOMAIN FROM NHERF1
Descriptor:Na(+)/H(+) exchange regulatory cofactor NHE-RF1
Authors:Bhattacharya, S., Ju, J.H., Cowburn, D., Bu, Z.
Deposit date:2012-11-06
Release date:2013-04-24
Last modified:2013-07-17
Method:SOLUTION NMR
Cite:Ligand-Induced Dynamic Changes in Extended PDZ Domains from NHERF1.
J.Mol.Biol., 425, 2013
2M0U
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COMPLEX STRUCTURE OF C-TERMINAL CFTR PEPTIDE AND EXTENDED PDZ1 DOMAIN FROM NHERF1
Descriptor:Na(+)/H(+) exchange regulatory cofactor NHE-RF1, C-terminal CFTR peptide
Authors:Bhattacharya, S., Ju, J.H., Cowburn, D., Bu, Z.
Deposit date:2012-11-06
Release date:2013-04-24
Last modified:2013-07-17
Method:SOLUTION NMR
Cite:Ligand-Induced Dynamic Changes in Extended PDZ Domains from NHERF1.
J.Mol.Biol., 425, 2013
2M0V
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COMPLEX STRUCTURE OF C-TERMINAL CFTR PEPTIDE AND EXTENDED PDZ2 DOMAIN FROM NHERF1
Descriptor:Na(+)/H(+) exchange regulatory cofactor NHE-RF1, C-terminal CFTR peptide
Authors:Bhattacharya, S., Ju, J.H., Cowburn, D., Bu, Z.
Deposit date:2012-11-06
Release date:2013-04-24
Last modified:2013-07-17
Method:SOLUTION NMR
Cite:Ligand-Induced Dynamic Changes in Extended PDZ Domains from NHERF1.
J.Mol.Biol., 425, 2013
2WAL
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CRYSTAL STRUCTURE OF HUMAN GADD45GAMMA
Descriptor:GROWTH ARREST AND DNA-DAMAGE-INDUCIBLE PROTEIN GADD45 GAMMA, MALONIC ACID
Authors:Bhattacharya, S., Mueller, J.J., Roske, Y., Turnbull, A.P., Quedenau, C., Goetz, F., Buessow, K., Heinemann, U.
Deposit date:2009-02-09
Release date:2009-03-03
Last modified:2015-04-22
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:The Crystal Structure of Human Gadd45Gamma
To be Published
4O8G
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STRUCTURE OF INFRARED FLUORESCENT PROTEIN 1.4
Descriptor:Bacteriophytochrome, 3-[2-[(Z)-[3-(2-carboxyethyl)-5-[(Z)-(4-ethenyl-3-methyl-5-oxidanylidene-pyrrol-2-ylidene)methyl]-4-methyl-pyrrol-1-ium-2-ylidene]methyl]-5-[(Z)-[(3E)-3-ethylidene-4-methyl-5-oxidanylidene-pyrrolidin-2-ylidene]methyl]-4-methyl-1H-pyrrol-3-yl]propanoic acid, 3-[2-[(Z)-[5-[(Z)-(4-ethenyl-3-methyl-5-oxidanylidene-pyrrol-2-ylidene)methyl]-3-(3-hydroxy-3-oxopropyl)-4-methyl-pyrrol-1-ium-2-ylidene]methyl]-5-[(Z)-[(3E,4R)-3-ethylidene-4-methyl-5-oxidanylidene-pyrrolidin-2-ylidene]methyl]-4-methyl-1H-pyrrol-3-yl]propanoic acid
Authors:Bhattacharya, S., Forest, K.T.
Deposit date:2013-12-27
Release date:2014-10-01
Last modified:2014-12-03
Method:X-RAY DIFFRACTION (1.652 Å)
Cite:Origins of fluorescence in evolved bacteriophytochromes.
J.Biol.Chem., 289, 2014
4OY2
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CRYSTAL STRUCTURE OF TAF1-TAF7, A TFIID SUBCOMPLEX
Descriptor:Transcription initiation factor TFIID subunit 1, Transcription initiation factor TFIID subunit 7, ZINC ION, ...
Authors:Bhattacharya, S., Lou, X., Rajashankar, K., Jacobson, R.H., Webb, P.
Deposit date:2014-02-10
Release date:2014-06-25
Last modified:2017-09-06
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Structural and functional insight into TAF1-TAF7, a subcomplex of transcription factor II D.
Proc.Natl.Acad.Sci.USA, 111, 2014
4Z1W
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CRYSTAL STRUCTURE OF MONOMERIC BACTERIOPHYTOCHROME MUTANT D207L Y263F FROM SYNCHROTRON
Descriptor:Bacteriophytochrome, 3-[2-[(Z)-[3-(2-carboxyethyl)-5-[(Z)-(4-ethenyl-3-methyl-5-oxidanylidene-pyrrol-2-ylidene)methyl]-4-methyl-pyrrol-1-ium-2-ylidene]methyl]-5-[(Z)-[(3E)-3-ethylidene-4-methyl-5-oxidanylidene-pyrrolidin-2-ylidene]methyl]-4-methyl-1H-pyrrol-3-yl]propanoic acid, 3-[2-[(Z)-[5-[(Z)-(4-ethenyl-3-methyl-5-oxidanylidene-pyrrol-2-ylidene)methyl]-3-(3-hydroxy-3-oxopropyl)-4-methyl-pyrrol-1-ium-2-ylidene]methyl]-5-[(Z)-[(3E,4R)-3-ethylidene-4-methyl-5-oxidanylidene-pyrrolidin-2-ylidene]methyl]-4-methyl-1H-pyrrol-3-yl]propanoic acid
Authors:Bhattacharya, S., Satyshur, K.A., Wangkanont, K., Lehtivuori, H., Forest, K.T.
Deposit date:2015-03-27
Release date:2016-01-20
Method:X-RAY DIFFRACTION (1.3 Å)
Cite:Removal of Chromophore-Proximal Polar Atoms Decreases Water Content and Increases Fluorescence in a Near Infrared Phytofluor.
Front Mol Biosci, 2, 2015
4ZRR
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CRYSTAL STRUCTURE OF MONOMERIC BACTERIOPHYTOCHROME MUTANT D207L Y263F AT 1.5 A RESOLUTION USING A HOME SOURCE.
Descriptor:Bacteriophytochrome, 3-[2-[(Z)-[3-(2-carboxyethyl)-5-[(Z)-(4-ethenyl-3-methyl-5-oxidanylidene-pyrrol-2-ylidene)methyl]-4-methyl-pyrrol-1-ium-2-ylidene]methyl]-5-[(Z)-[(3E)-3-ethylidene-4-methyl-5-oxidanylidene-pyrrolidin-2-ylidene]methyl]-4-methyl-1H-pyrrol-3-yl]propanoic acid, 3-[2-[(Z)-[5-[(Z)-(4-ethenyl-3-methyl-5-oxidanylidene-pyrrol-2-ylidene)methyl]-3-(3-hydroxy-3-oxopropyl)-4-methyl-pyrrol-1-ium-2-ylidene]methyl]-5-[(Z)-[(3E,4R)-3-ethylidene-4-methyl-5-oxidanylidene-pyrrolidin-2-ylidene]methyl]-4-methyl-1H-pyrrol-3-yl]propanoic acid, ...
Authors:Bhattacharya, S., Satyshur, K.A., Lehtivuori, H., Forest, K.T.
Deposit date:2015-05-12
Release date:2016-01-20
Last modified:2017-09-20
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Removal of Chromophore-Proximal Polar Atoms Decreases Water Content and Increases Fluorescence in a Near Infrared Phytofluor.
Front Mol Biosci, 2, 2015
1I87
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SOLUTION STRUCTURE OF THE WATER-SOLUBLE FRAGMENT OF RAT HEPATIC APOCYTOCHROME B5
Descriptor:CYTOCHROME B5
Authors:Falzone, C.J., Wang, Y., Vu, B.C., Scott, N.L., Bhattacharya, S., Lecomte, J.T.
Deposit date:2001-03-12
Release date:2001-05-16
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Structural and dynamic perturbations induced by heme binding in cytochrome b5.
Biochemistry, 40, 2001
1I8C
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SOLUTION STRUCTURE OF THE WATER-SOLUBLE FRAGMENT OF RAT HEPATIC APOCYTOCHROME B5
Descriptor:CYTOCHROME B5
Authors:Falzone, C.J., Wang, Y., Vu, B.C., Scott, N.L., Bhattacharya, S., Lecomte, J.T.
Deposit date:2001-03-13
Release date:2001-05-16
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Structural and dynamic perturbations induced by heme binding in cytochrome b5.
Biochemistry, 40, 2001
1XXG
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CRYSTAL STRUCTURE OF STAPHYLOCOCCAL ENTEROTOXIN G
Descriptor:enterotoxin, SULFATE ION
Authors:Fernandez, M.M., Bhattacharya, S., Malchiodi, E.L., Mariuzza, R.A.
Deposit date:2004-11-05
Release date:2006-02-21
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:The Crystal Structure of Staphylococcal Enterotoxin G and binding affinity to T-cell receptor and MHC class II molecule
To be Published
4A04
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STRUCTURE OF THE DNA-BOUND T-BOX DOMAIN OF HUMAN TBX1, A TRANSCRIPTION FACTOR ASSOCIATED WITH THE DIGEORGE SYNDROME
Descriptor:T-BOX TRANSCRIPTION FACTOR TBX1, DNA
Authors:El Omari, K., De Mesmaeker, J., Karia, D., Ginn, H., Bhattacharya, S., Mancini, E.J.
Deposit date:2011-09-07
Release date:2011-10-12
Last modified:2012-09-12
Method:X-RAY DIFFRACTION (2.58 Å)
Cite:Structure of the DNA-Bound T-Box Domain of Human Tbx1, a Transcription Factor Associated with the Digeorge Syndrome
Proteins, 80, 2012
5E0O
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BRUGIA MALAYI TREHALOSE-6 PHOSPHATE PHOSPHATASE IN COMPLEX WITH PEG AT THE ACTIVE SITE.
Descriptor:Trehalose-phosphatase, MAGNESIUM ION, SULFATE ION, ...
Authors:Agarwal, A., Misra-Bhattacharya, S., Ravishankar, R.
Deposit date:2015-09-29
Release date:2015-10-28
Method:X-RAY DIFFRACTION (3 Å)
Cite:Brugia malayi Trehalose Phosphate Phosphatase in complex with PEG at the active site
To Be Published, 2015
4IJG
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CRYSTAL STRUCTURE OF MONOMERIC BACTERIOPHYTOCHROME
Descriptor:Bacteriophytochrome, 3-[2-[(Z)-[3-(2-carboxyethyl)-5-[(Z)-(4-ethenyl-3-methyl-5-oxidanylidene-pyrrol-2-ylidene)methyl]-4-methyl-pyrrol-1-ium-2-ylidene]methyl]-5-[(Z)-[(3E)-3-ethylidene-4-methyl-5-oxidanylidene-pyrrolidin-2-ylidene]methyl]-4-methyl-1H-pyrrol-3-yl]propanoic acid, GLYCEROL, ...
Authors:Auldridge, M.E.
Deposit date:2012-12-21
Release date:2013-12-25
Last modified:2014-12-03
Method:X-RAY DIFFRACTION (1.701 Å)
Cite:Origins of fluorescence in evolved bacteriophytochromes.
J.Biol.Chem., 289, 2014
6H8R
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CRYSTAL STRUCTURE OF THE HUMAN PROTEIN TYROSINE PHOSPHATASE PTPN5 (STEP) IN COMPLEX WITH COMPOUND 2
Descriptor:Tyrosine-protein phosphatase non-receptor type 5, SULFATE ION, 3-[(2~{S})-2-azanylpropyl]-5-(trifluoromethyl)phenol
Authors:Hoerer, S., Fiegen, D., Schnapp, G.
Deposit date:2018-08-03
Release date:2018-09-26
Last modified:2019-01-23
Method:X-RAY DIFFRACTION (1.66 Å)
Cite:Allosteric Activation of Striatal-Enriched Protein Tyrosine Phosphatase (STEP, PTPN5) by a Fragment-like Molecule.
J. Med. Chem., 62, 2019
6H8S
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CRYSTAL STRUCTURE OF THE MOUSE PROTEIN TYROSINE PHOSPHATASE PTPN5 (STEP) IN COMPLEX WITH COMPOUND BI-0314
Descriptor:Tyrosine-protein phosphatase non-receptor type 5, 1-[3-piperidin-4-yl-5-(trifluoromethyl)phenyl]guanidine
Authors:Fiegen, D., Schnapp, G.
Deposit date:2018-08-03
Release date:2018-09-26
Last modified:2019-01-23
Method:X-RAY DIFFRACTION (1.771 Å)
Cite:Allosteric Activation of Striatal-Enriched Protein Tyrosine Phosphatase (STEP, PTPN5) by a Fragment-like Molecule.
J. Med. Chem., 62, 2019
5T04
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STRUCTURE OF CONSTITUTIVELY ACTIVE NEUROTENSIN RECEPTOR
Descriptor:Neurotensin receptor type 1,Endolysin,Neurotensin receptor type 1, ARG-ARG-PRO-TYR-ILE-LEU, 3,3',3''-phosphanetriyltripropanoic acid, ...
Authors:Krumm, B., Botos, I., Grisshammer, R.
Deposit date:2016-08-15
Release date:2016-12-21
Method:X-RAY DIFFRACTION (3.3 Å)
Cite:Structure and dynamics of a constitutively active neurotensin receptor.
Sci Rep, 6, 2016
6DBP
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RNA-RECOGNITION MOTIF 1 OF HUMAN MSI2
Descriptor:RNA-binding protein Musashi homolog 2
Authors:Goldgur, Y., Kharas, M.G., Minuesa, G.
Deposit date:2018-05-03
Release date:2019-05-08
Last modified:2019-07-03
Method:X-RAY DIFFRACTION (1.603 Å)
Cite:Small-molecule targeting of MUSASHI RNA-binding activity in acute myeloid leukemia.
Nat Commun, 10, 2019
2JTT
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SOLUTION STRUCTURE OF CALCIUM LOADED S100A6 BOUND TO C-TERMINAL SIAH-1 INTERACTING PROTEIN
Descriptor:Protein S100-A6, Calcyclin-binding protein
Authors:Lee, Y., Chazin, W.J.
Deposit date:2007-08-06
Release date:2008-08-19
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Structure of the S100A6 complex with a fragment from the C-terminal domain of Siah-1 interacting protein: a novel mode for S100 protein target recognition.
Biochemistry, 47, 2008
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