Author results

2PRK
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SYNCHROTRON X-RAY DATA COLLECTION AND RESTRAINED LEAST-SQUARES REFINEMENT OF THE CRYSTAL STRUCTURE OF PROTEINASE K AT 1.5 ANGSTROMS RESOLUTION
Descriptor:PROTEINASE K, CALCIUM ION
Authors:Betzel, C., Pal, G.P., Saenger, W.
Deposit date:1987-11-30
Release date:1988-04-16
Last modified:2017-11-29
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Synchrotron X-ray data collection and restrained least-squares refinement of the crystal structure of proteinase K at 1.5 A resolution.
Acta Crystallogr.,Sect.B, 44, 1988
353D
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CRYSTAL STRUCTURE OF DOMAIN A OF THERMUS FLAVUS 5S RRNA AND THE CONTRIBUTION OF WATER MOLECULES TO ITS STRUCTURE
Descriptor:RNA (5'-R(*AP*UP*CP*CP*CP*CP*CP*GP*UP*GP*CP*C)-3'), RNA (5'-R(*GP*GP*UP*GP*CP*GP*GP*GP*GP*GP*AP*U)-3')
Authors:Betzel, C., Lorenz, S., Furste, J.P., Bald, R., Zhang, M., Schneider, T.R., Wilson, K.S., Erdmann, V.A.
Deposit date:1997-09-29
Release date:1997-11-10
Last modified:2018-02-14
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Crystal structure of domain A of Thermus flavus 5S rRNA and the contribution of water molecules to its structure.
FEBS Lett., 351, 1994
1PEK
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STRUCTURE OF THE COMPLEX OF PROTEINASE K WITH A SUBSTRATE-ANALOGUE HEXA-PEPTIDE INHIBITOR AT 2.2 ANGSTROMS RESOLUTION
Descriptor:PROTEINASE K, PEPTIDE PRO-ALA-PRO-PHE, D-DAL-ALA-NH2
Authors:Betzel, C., Singh, T.P., Visanji, M., Peters, K., Fittkau, S., Saenger, W., Wilson, K.S.
Deposit date:1993-01-19
Release date:1994-01-31
Last modified:2017-11-29
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structure of the complex of proteinase K with a substrate analogue hexapeptide inhibitor at 2.2-A resolution.
J.Biol.Chem., 268, 1993
1SVN
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SAVINASE
Descriptor:SAVINASE (TM), CALCIUM ION
Authors:Betzel, C., Klupsch, S., Papendorf, G., Hastrup, S., Branner, S., Wilson, K.S.
Deposit date:1995-09-01
Release date:1996-10-14
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:Crystal structure of the alkaline proteinase Savinase from Bacillus lentus at 1.4 A resolution.
J.Mol.Biol., 223, 1992
1IC6
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STRUCTURE OF A SERINE PROTEASE PROTEINASE K FROM TRITIRACHIUM ALBUM LIMBER AT 0.98 A RESOLUTION
Descriptor:PROTEINASE K, CALCIUM ION, NITRATE ION
Authors:Betzel, C., Gourinath, S., Kumar, P., Kaur, P., Perbandt, M., Eschenburg, S., Singh, T.P.
Deposit date:2001-03-30
Release date:2001-04-11
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (0.98 Å)
Cite:Structure of a serine protease proteinase K from Tritirachium album limber at 0.98 A resolution.
Biochemistry, 40, 2001
2CTX
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THE REFINED CRYSTAL STRUCTURE OF ALPHA-COBRATOXIN FROM NAJA NAJA SIAMENSIS AT 2.4-ANGSTROMS RESOLUTION
Descriptor:ALPHA-COBRATOXIN
Authors:Betzel, C., Lange, G., Pal, G.P., Wilson, K.S., Maelicke, A., Saenger, W.
Deposit date:1991-09-24
Release date:1993-10-31
Last modified:2017-11-29
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:The refined crystal structure of alpha-cobratoxin from Naja naja siamensis at 2.4-A resolution.
J.Biol.Chem., 266, 1991
1EGP
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PROTEINASE INHIBITOR EGLIN C WITH HYDROLYSED REACTIVE CENTER
Descriptor:EGLIN-C
Authors:Dauter, Z., Lamzin, V., Betzel, C., Wilson, K.S.
Deposit date:1995-09-01
Release date:1995-12-07
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structure of the proteinase inhibitor eglin c with hydrolysed reactive centre at 2.0 A resolution.
FEBS Lett., 317, 1993
1KPM
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FIRST STRUCTURAL EVIDENCE OF A SPECIFIC INHIBITION OF PHOSPHOLIPASE A2 BY VITAMIN E AND ITS IMPLICATIONS IN INFLAMMATION: CRYSTAL STRUCTURE OF THE COMPLEX FORMED BETWEEN PHOSPHOLIPASE A2 AND VITAMIN E AT 1.8 A RESOLUTION.
Descriptor:Phospholipase A2, VITAMIN E, ACETIC ACID
Authors:Chandra, V., Jasti, J., Kaur, P., Betzel, C., Srinivasan, A., Singh, T.P.
Deposit date:2002-01-01
Release date:2002-07-10
Last modified:2017-10-11
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:First Structural Evidence of a Specific Inhibition of Phospholipase A2 by alpha-Tocopherol (Vitamin E) and its Implications in Inflammation: Crystal Structure of the Complex Formed Between Phospholipase A2 and alpha-Tocopherol at 1.8 A Resolution
J.Mol.Biol., 320, 2002
1JQ9
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CRYSTAL STRUCTURE OF A COMPLEX FORMED BETWEEN PHOSPHOLIPASE A2 FROM DABOIA RUSSELLI PULCHELLA AND A DESIGNED PENTAPEPTIDE PHE-LEU-SER-TYR-LYS AT 1.8 RESOLUTION
Descriptor:Phospholipase A2, Peptide inhibitor, ACETIC ACID
Authors:Chandra, V., Jasti, J., Kaur, P., Dey, S., Betzel, C., Singh, T.P.
Deposit date:2001-08-04
Release date:2002-11-06
Last modified:2017-10-04
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Crystal Structure of a Complex Formed between a Snake Venom Phospholipase A2 and a Potent Peptide Inhibitor Phe-Leu-Ser-Tyr-Lys at 1.8 A Resolution
J.BIOL.CHEM., 277, 2002
1JQ8
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DESIGN OF SPECIFIC INHIBITORS OF PHOSPHOLIPASE A2: CRYSTAL STRUCTURE OF A COMPLEX FORMED BETWEEN PHOSPHOLIPASE A2 FROM DABOIA RUSSELLI PULCHELLA AND A DESIGNED PENTAPEPTIDE LEU-ALA-ILE-TYR-SER AT 2.0 RESOLUTION
Descriptor:Phospholipase A2, Peptide inhibitor, SULFATE ION, ...
Authors:Chandra, V., Jasti, J., Kaur, P., Dey, S., Betzel, C., Singh, T.P.
Deposit date:2001-08-04
Release date:2002-11-06
Last modified:2017-10-04
Method:X-RAY DIFFRACTION (2 Å)
Cite:Design of specific peptide inhibitors of phospholipase A2: structure of a complex formed between Russell's viper phospholipase A2 and a designed peptide Leu-Ala-Ile-Tyr-Ser (LAIYS).
ACTA CRYSTALLOGR.,SECT.D, 58, 2002
1BH6
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SUBTILISIN DY IN COMPLEX WITH THE SYNTHETIC INHIBITOR N-BENZYLOXYCARBONYL-ALA-PRO-PHE-CHLOROMETHYL KETONE
Descriptor:SUBTILISIN DY, CALCIUM ION, SODIUM ION, ...
Authors:Eschenburg, S., Genov, N., Wilson, K.S., Betzel, C.
Deposit date:1998-06-15
Release date:1998-11-04
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Crystal structure of subtilisin DY, a random mutant of subtilisin Carlsberg.
Eur.J.Biochem., 257, 1998
1BJR
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COMPLEX FORMED BETWEEN PROTEOLYTICALLY GENERATED LACTOFERRIN FRAGMENT AND PROTEINASE K
Descriptor:PROTEINASE K, LACTOFERRIN, CALCIUM ION
Authors:Singh, T.P., Sharma, S., Karthikeyan, S., Betzel, C., Bhatia, K.L.
Deposit date:1998-06-27
Release date:1998-11-04
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.44 Å)
Cite:Crystal structure of a complex formed between proteolytically-generated lactoferrin fragment and proteinase K.
Proteins, 33, 1998
1EMR
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CRYSTAL STRUCTURE OF HUMAN LEUKEMIA INHIBITORY FACTOR (LIF)
Descriptor:LEUKEMIA INHIBITORY FACTOR
Authors:Robinson, R.C., Heath, J.K., Hawkins, N., Samal, B., Jones, E.Y., Betzel, C.
Deposit date:2000-03-17
Release date:2001-03-21
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3.5 Å)
Cite:Species Variation in Receptor Binding Site Revealed by the Medium Resolution X-ray Structure of Human Leukemia Inhibitory Factor
to be published
1L3P
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CRYSTAL STRUCTURE OF THE FUNCTIONAL DOMAIN OF THE MAJOR GRASS POLLEN ALLERGEN PHL P 5B
Descriptor:POLLEN ALLERGEN Phl p 5b, PHOSPHATE ION, MAGNESIUM ION
Authors:Rajashankar, K.R., Bufe, A., Weber, W., Eschenburg, S., Lindner, B., Betzel, C.
Deposit date:2002-02-28
Release date:2003-02-28
Last modified:2017-10-11
Method:X-RAY DIFFRACTION (1.98 Å)
Cite:Structure of the functional domain of the major grass-pollen allergen Phlp 5b.
Acta Crystallogr.,Sect.D, 58, 2002
1NTN
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THE CRYSTAL STRUCTURE OF NEUROTOXIN-I FROM NAJA NAJA OXIANA AT 1.9 ANGSTROMS RESOLUTION
Descriptor:NEUROTOXIN I
Authors:Mikhailov, A.M., Nickitenko, A.V., Vainshtein, B.K., Betzel, C., Wilson, K.
Deposit date:1994-09-26
Release date:1995-05-08
Last modified:2017-11-29
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Three-dimensional structure of neurotoxin-1 from Naja naja oxiana venom at 1.9 A resolution.
Febs Lett., 320, 1993
1FV0
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FIRST STRUCTURAL EVIDENCE OF THE INHIBITION OF PHOSPHOLIPASE A2 BY ARISTOLOCHIC ACID: CRYSTAL STRUCTURE OF A COMPLEX FORMED BETWEEN PHOSPHOLIPASE A2 AND ARISTOLOCHIC ACID
Descriptor:PHOSPHOLIPASE A2, SULFATE ION, ACETATE ION, ...
Authors:Chandra, V., Jasti, J., Kaur, P., Srinivasan, A., Betzel, C., Singh, T.P.
Deposit date:2000-09-18
Release date:2002-08-28
Last modified:2018-01-24
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Structural Basis of Phospholipase A2 Inhibition for the Synthesis of Prostaglandins by the Plant Alkaloid Aristolochic Acid from a 1.7 A Crystal Structure
Biochemistry, 41, 2002
4HWY
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TRYPANOSOMA BRUCEI PROCATHEPSIN B SOLVED FROM 40 FS FREE-ELECTRON LASER PULSE DATA BY SERIAL FEMTOSECOND X-RAY CRYSTALLOGRAPHY
Descriptor:Cysteine peptidase C (CPC), N-ACETYL-D-GLUCOSAMINE, BETA-D-MANNOSE
Authors:Redecke, L., Nass, K., DePonte, D.P., White, T.A., Rehders, D., Barty, A., Stellato, F., Liang, M., Barends, T.R.M., Boutet, S., Williams, G.W., Messerschmidt, M., Seibert, M.M., Aquila, A., Arnlund, D., Bajt, S., Barth, T., Bogan, M.J., Caleman, C., Chao, T.-C., Doak, R.B., Fleckenstein, H., Frank, M., Fromme, R., Galli, L., Grotjohann, I., Hunter, M.S., Johansson, L.C., Kassemeyer, S., Katona, G., Kirian, R.A., Koopmann, R., Kupitz, C., Lomb, L., Martin, A.V., Mogk, S., Neutze, R., Shoemann, R.L., Steinbrener, J., Timneanu, N., Wang, D., Weierstall, U., Zatsepin, N.A., Spence, J.C.H., Fromme, P., Schlichting, I., Duszenko, M., Betzel, C., Chapman, H.
Deposit date:2012-11-09
Release date:2012-12-05
Last modified:2018-02-14
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Natively inhibited Trypanosoma brucei cathepsin B structure determined by using an X-ray laser.
Science, 339, 2013
6GTH
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SERIAL FEMTOSECOND CRYSTALLOGRAPHY AT MEGAHERTZ PULSE RATES
Descriptor:Beta-lactamase, (2S,5R)-1-formyl-5-[(sulfooxy)amino]piperidine-2-carboxamide
Authors:Wiedorn, M., Oberthuer, D., Werner, N., Schubert, R., White, T.A., Mancuso, A., Perbandt, M., Betzel, C., Barty, A., Chapman, H.
Deposit date:2018-06-18
Release date:2018-10-10
Last modified:2018-11-14
Method:X-RAY DIFFRACTION (1.69 Å)
Cite:Megahertz serial crystallography.
Nat Commun, 9, 2018
6FDG
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NOVEL CRYSTAL STRUCTURE OF DHNA-COA THIOESTERASE FROM STAPHYLOCOCCUS AUREUS
Descriptor:4-hydroxybenzoyl-CoA thioesterase
Authors:Murad, A.M., Betzel, C., Wrenger, C.
Deposit date:2017-12-22
Release date:2018-02-21
Last modified:2018-03-14
Method:X-RAY DIFFRACTION (1.3 Å)
Cite:Novel crystal structure of DHNA-CoA Thioesterase from Staphylococcus aureus
To Be Published
1JLT
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VIPOXIN COMPLEX
Descriptor:PHOSPHOLIPASE A2 INHIBITOR, PHOSPHOLIPASE A2, (4R)-2-METHYLPENTANE-2,4-DIOL, ...
Authors:Banumathi, S., Rajashankar, K.R., Notzel, C., Aleksiev, B., Singh, T.P., Genov, N., Betzel, C.
Deposit date:2001-07-16
Release date:2001-10-31
Last modified:2018-01-31
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:Structure of the neurotoxic complex vipoxin at 1.4 A resolution.
Acta Crystallogr.,Sect.D, 57, 2001
1PA3
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CRYSTAL STRUCTURE OF GLUTATHIONE-S-TRANSFERASE FROM PLASMODIUM FALCIPARUM
Descriptor:Glutathione s-transferase, putative
Authors:Perbandt, M., Betzel, C., Liebau, E.
Deposit date:2003-05-13
Release date:2003-11-25
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Native and inhibited structure of a Mu class-related glutathione S-transferase from Plasmodium falciparum
J.Biol.Chem., 279, 2004
1Q4J
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CRYSTAL STRUCTURE OF PF-GST1 WITH ITS INHIBITOR S-HEXYL-GSH
Descriptor:Glutathione s-transferase, S-HEXYLGLUTATHIONE
Authors:Perbandt, M., Betzel, C., Liebau, E.
Deposit date:2003-08-04
Release date:2003-11-25
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Native and inhibited structure of a Mu class-related glutathione S-transferase from Plasmodium falciparum
J.Biol.Chem., 279, 2004
2AYW
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CRYSTAL STRUCTURE OF THE COMPLEX FORMED BETWEEN TRYPSIN AND A DESIGNED SYNTHETIC HIGHLY POTENT INHIBITOR IN THE PRESENCE OF BENZAMIDINE AT 0.97 A RESOLUTION
Descriptor:Cationic trypsin, CALCIUM ION, 2-[2-({[4-(DIAMINOMETHYL)PHENYL]AMINO}CARBONYL)-6-METHOXYPYRIDIN-3-YL]-5-{[(1-FORMYL-2,2-DIMETHYLPROPYL)AMINO]CARBONYL}BENZOIC ACID, ...
Authors:Sherawat, M., Kaur, P., Perbandt, M., Betzel, C., Slusarchyk, W.A., Bisacchi, G.S., Chang, C., Jacobson, B.L., Einspahr, H.M., Singh, T.P.
Deposit date:2005-09-09
Release date:2006-01-17
Last modified:2017-10-11
Method:X-RAY DIFFRACTION (0.97 Å)
Cite:Structure of the complex of trypsin with a highly potent synthetic inhibitor at 0.97 A resolution.
Acta Crystallogr.,Sect.D, 63, 2007
2HNL
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STRUCTURE OF THE PROSTAGLANDIN D SYNTHASE FROM THE PARASITIC NEMATODE ONCHOCERCA VOLVULUS
Descriptor:Glutathione S-transferase 1, GLUTATHIONE
Authors:Perbandt, M., Hoppner, J., Betzel, C., Liebau, E.
Deposit date:2006-07-13
Release date:2007-07-17
Last modified:2017-10-18
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structure of the extracellular glutathione S-transferase OvGST1 from the human pathogenic parasite Onchocerca volvulus.
J.Mol.Biol., 377, 2008
2V6W
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TRNASER ACCEPTOR STEM: CONFORMATION AND HYDRATION OF A MICROHELIX IN A CRYSTAL STRUCTURE AT 1.8 ANGSTROM RESOLUTION
Descriptor:5'-R(*GP*GP*AP*GP*AP*GP*AP)-3', 5'-R(*UP*CP*UP*CP*UP*CP*CP)-3'
Authors:Foerster, C., Brauer, A.B.E., Brode, S., Fuerste, J.P., Betzel, C., Erdmann, V.A.
Deposit date:2007-07-23
Release date:2007-11-06
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Trnaser Acceptor Stem: Conformation and Hydration of a Microhelix in a Crystal Structure at 1.8 A Resolution.
Acta Crystallogr.,Sect.D, 63, 2007