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5A8G
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BU of 5a8g by Molmil
Crystal structure of the wild-type Staphylococcus aureus N- acetylneurminic acid lyase in complex with fluoropyruvate
Descriptor: N-ACETYLNEURAMINATE LYASE
Authors:Stockwell, J, Daniels, A.D, Windle, C.L, Harman, T, Woodhall, T, Trinh, C.H, Lebel, T, Pearson, A.R, Mulholland, K, Berry, A, Nelson, A.
Deposit date:2015-07-15
Release date:2015-11-18
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (1.72 Å)
Cite:Evaluation of Fluoropyruvate as Nucleophile in Reactions Catalysed by N-Acetyl Neuraminic Acid Lyase Variants: Scope, Limitations and Stereoselectivity.
Org.Biomol.Chem., 14, 2016
5LKY
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X-ray crystal structure of N-acetylneuraminic acid lyase in complex with pyruvate, with the phenylalanine at position 190 replaced with the non-canonical amino acid dihydroxypropylcysteine.
Descriptor: DI(HYDROXYETHYL)ETHER, N-acetylneuraminate lyase
Authors:Windle, C.L, Trinh, C.H, Pearson, A.R, Nelson, A.S, Berry, A.
Deposit date:2016-07-25
Release date:2017-03-22
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Extending enzyme molecular recognition with an expanded amino acid alphabet.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
4AMA
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BU of 4ama by Molmil
Crystal Structure of N-acetylneuraminic acid lyase from Staphylococcus aureus with the chemical modification thia-lysine at position 165 in complex with pyruvate
Descriptor: N-ACETYLNEURAMINATE LYASE
Authors:Timms, N, Polyakova, A, Windle, C.L, Trinh, C.H, Nelson, A, Pearson, A.R, Berry, A.
Deposit date:2012-03-08
Release date:2013-01-23
Last modified:2019-07-10
Method:X-RAY DIFFRACTION (2.35 Å)
Cite:Structural insights into the recovery of aldolase activity in N-acetylneuraminic acid lyase by replacement of the catalytically active lysine with gamma-thialysine by using a chemical mutagenesis strategy.
Chembiochem, 14, 2013
6HNM
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BU of 6hnm by Molmil
Crystal structure of IdmH 96-104 loop truncation variant
Descriptor: putative polyketide cyclase IdmH
Authors:Drulyte, I, Obajdin, J, Trinh, C, Hemsworth, G.R, Berry, A.
Deposit date:2018-09-16
Release date:2019-11-06
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystal structure of the putative cyclase IdmH from the indanomycin nonribosomal peptide synthase/polyketide synthase.
Iucrj, 6, 2019
6HNN
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BU of 6hnn by Molmil
Crystal structure of wild-type IdmH, a putative polyketide cyclase from Streptomyces antibioticus
Descriptor: Putative polyketide cyclase IdmH
Authors:Drulyte, I, Obajdin, J, Trinh, C, Hemsworth, G.R, Berry, A.
Deposit date:2018-09-16
Release date:2019-11-06
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Crystal structure of the putative cyclase IdmH from the indanomycin nonribosomal peptide synthase/polyketide synthase.
Iucrj, 6, 2019
6HNL
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BU of 6hnl by Molmil
Selenomethionine derivative of IdmH 96-104 loop truncation variant
Descriptor: Putative polyketide cyclase IdmH
Authors:Drulyte, I, Obajdin, J, Trinh, C, Hemsworth, G.R, Berry, A.
Deposit date:2018-09-16
Release date:2019-11-06
Last modified:2019-11-20
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Crystal structure of the putative cyclase IdmH from the indanomycin nonribosomal peptide synthase/polyketide synthase.
Iucrj, 6, 2019
4AH7
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BU of 4ah7 by Molmil
Structure of Wild Type Stapylococcus aureus N-acetylneuraminic acid lyase in complex with pyruvate
Descriptor: N-ACETYLNEURAMINATE LYASE
Authors:Timms, N, Poyakova, A, Windle, C.L, Trinh, C.H, Nelson, A, Pearson, A.R, Berry, A.
Deposit date:2012-02-03
Release date:2013-01-23
Last modified:2013-03-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structural Insights Into the Recovery of Aldolase Activity in N-Acetylneuraminic Acid Lyase by Replacement of the Catalytically Active Lysine with Gamma-Thialysine by Using a Chemical Mutagenesis Strategy.
Chembiochem, 14, 2013
2WO5
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BU of 2wo5 by Molmil
Structure of wild type E. coli N-acetylneuraminic acid lyase in space group P21 crystal form I
Descriptor: N-ACETYLNEURAMINATE LYASE
Authors:Campeotto, I, Bolt, A.H, Harman, T.A, Trinh, C.H, Dennis, C.A, Phillips, S.E.V, Pearson, A.R, Nelson, A, Berry, A.
Deposit date:2009-07-21
Release date:2010-08-25
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structural Insights Into Substrate Specificity in Variants of N-Acetylneuraminic Acid Lyase Produced by Directed Evolution.
J.Mol.Biol., 404, 2010
2WNN
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BU of 2wnn by Molmil
Structure of wild type E. coli N-acetylneuraminic acid lyase in complex with pyruvate in space group P21
Descriptor: N-ACETYLNEURAMINATE LYASE, PENTAETHYLENE GLYCOL, SODIUM ION
Authors:Campeotto, I, Bolt, A.H, Harman, T.A, Trinh, C.H, Dennis, C.A, Phillips, S.E.V, Pearson, A.R, Nelson, A, Berry, A.
Deposit date:2009-07-13
Release date:2010-08-25
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:Structural Insights Into Substrate Specificity in Variants of N-Acetylneuraminic Acid Lyase Produced by Directed Evolution.
J.Mol.Biol., 404, 2010
2WPB
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BU of 2wpb by Molmil
Crystal structure of the E192N mutant of E. Coli N-acetylneuraminic acid lyase in complex with pyruvate and the inhibitor (2R,3R)-2,3,4- trihydroxy-N,N-dipropylbutanamide in space group P21 crystal form I
Descriptor: (2R,3R)-2,3,4-TRIHYDROXY-N,N-DIPROPYLBUTANAMIDE, N-ACETYLNEURAMINATE LYASE
Authors:Campeotto, I, Bolt, A.H, Harman, T.A, Trinh, C.H, Dennis, C.A, Phillips, S.E.V, Pearson, A.R, Nelson, A, Berry, A.
Deposit date:2009-08-03
Release date:2010-08-25
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:Structural Insights Into Substrate Specificity in Variants of N-Acetylneuraminic Acid Lyase Produced by Directed Evolution.
J.Mol.Biol., 404, 2010
2WNZ
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Structure of the E192N mutant of E. coli N-acetylneuraminic acid lyase in complex with pyruvate in space group P21 crystal form I
Descriptor: (2S)-2-HYDROXYPROPANOIC ACID, 2-ETHOXYETHANOL, LACTIC ACID, ...
Authors:Campeotto, I, Bolt, A.H, Harman, T.A, Trinh, C.H, Dennis, C.A, Phillips, S.E.V, Pearson, A.R, Nelson, A, Berry, A.
Deposit date:2009-07-21
Release date:2010-08-25
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Structural Insights Into Substrate Specificity in Variants of N-Acetylneuraminic Acid Lyase Produced by Directed Evolution.
J.Mol.Biol., 404, 2010
2WNQ
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BU of 2wnq by Molmil
Structure of the E192N mutant of E. coli N-acetylneuraminic acid lyase in space group P21
Descriptor: CHLORIDE ION, N-ACETYLNEURAMINATE LYASE
Authors:Campeotto, I, Bolt, A.H, Harman, T.A, Trinh, C.H, Dennis, C.A, Phillips, S.E.V, Pearson, A.R, Nelson, A, Berry, A.
Deposit date:2009-07-17
Release date:2010-08-25
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structural Insights Into Substrate Specificity in Variants of N-Acetylneuraminic Acid Lyase Produced by Directed Evolution.
J.Mol.Biol., 404, 2010
2XFW
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BU of 2xfw by Molmil
Structure of the E192N mutant of E. coli N-acetylneuraminic acid lyase in complex with pyruvate in crystal form III
Descriptor: N-ACETYLNEURAMINIC ACID LYASE, PENTAETHYLENE GLYCOL, PYRUVIC ACID
Authors:Campeotto, I, Murshudov, G.N, Bolt, A.H, Trinh, C.H, Phillips, S.E.V, Nelson, A, Pearson, A.R, Berry, A.
Deposit date:2010-05-28
Release date:2010-09-22
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:Structural Insights Into Substrate Specificity in Variants of N-Acetylneuraminic Acid Lyase Produced by Directed Evolution.
To be Published
4AHQ
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BU of 4ahq by Molmil
Crystal Structure of N-acetylneuraminic acid lyase mutant K165C from Staphylococcus aureus
Descriptor: N-ACETYLNEURAMINATE LYASE
Authors:Timms, N, Polyakova, A, Windle, C.L, Trinh, C.H, Nelson, A, Trinh, A.R, Berry, A.
Deposit date:2012-02-06
Release date:2013-01-23
Last modified:2013-03-13
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Structural Insights Into the Recovery of Aldolase Activity in N-Acetylneuraminic Acid Lyase by Replacement of the Catalytically Active Lysine with Gamma-Thialysine by Using a Chemical Mutagenesis Strategy.
Chembiochem, 14, 2013
4AHO
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BU of 4aho by Molmil
Crystal Structure of N-acetylneuraminic acid lyase from Staphylococcus aureus with the chemical modification thia-lysine at position 165
Descriptor: CHLORIDE ION, N-ACETYLNEURAMINATE LYASE
Authors:Timms, N, Polyakova, A, Windle, C.L, Trinh, C.H, Nelson, A, Trinh, A.R, Berry, A.
Deposit date:2012-02-06
Release date:2013-01-23
Last modified:2013-03-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural Insights Into the Recovery of Aldolase Activity in N-Acetylneuraminic Acid Lyase by Replacement of the Catalytically Active Lysine with Gamma-Thialysine by Using a Chemical Mutagenesis Strategy.
Chembiochem, 14, 2013
4AHP
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BU of 4ahp by Molmil
Crystal Structure of Wild Type N-acetylneuraminic acid lyase from Staphylococcus aureus
Descriptor: CHLORIDE ION, N-ACETYLNEURAMINATE LYASE
Authors:Timms, N, Polyakova, A, Windle, C.L, Trinh, C.H, Nelson, A, Trinh, A.R, Berry, A.
Deposit date:2012-02-06
Release date:2013-01-23
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structural Insights Into the Recovery of Aldolase Activity in N-Acetylneuraminic Acid Lyase by Replacement of the Catalytically Active Lysine with Gamma-Thialysine by Using a Chemical Mutagenesis Strategy.
Chembiochem, 14, 2013
4BWL
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BU of 4bwl by Molmil
Structure of the Y137A mutant of E. coli N-acetylneuraminic acid lyase in complex with pyruvate, N-acetyl-D-mannosamine and N- acetylneuraminic acid
Descriptor: 2-(ACETYLAMINO)-2-DEOXY-D-MANNOSE, 5-(acetylamino)-3,5-dideoxy-D-glycero-D-galacto-non-2-ulosonic acid, N-ACETYLNEURAMINATE LYASE, ...
Authors:Campeotto, I, Phillips, S.E.V, Pearson, A.R, Nelson, A, Berry, A.
Deposit date:2013-07-03
Release date:2014-02-19
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2 Å)
Cite:The Reaction Mechanism of N-Acetylneuraminic Acid Lyase Revealed by a Combination of Crystallography, Qm/Mm Simulation and Mutagenesis.
Acs Chem.Biol., 9, 2014
1GYN
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BU of 1gyn by Molmil
Class II fructose 1,6-bisphosphate aldolase with Cadmium (not Zinc) in the active site
Descriptor: CADMIUM ION, FRUCTOSE-BISPHOSPHATE ALDOLASE II
Authors:Hall, D.R, Kemp, L.E, Leonard, G.A, Berry, A, Hunter, W.N.
Deposit date:2002-04-27
Release date:2003-02-26
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:The Organization of Divalent Cations in the Active Site of Cadmium Escherichia Coli Fructose 1,6-Bisphosphate Aldolase
Acta Crystallogr.,Sect.D, 59, 2003
2WKJ
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BU of 2wkj by Molmil
Crystal structure of the E192N mutant of E. Coli N-acetylneuraminic acid lyase in complex with pyruvate at 1.45A resolution in space group P212121
Descriptor: N-ACETYLNEURAMINATE LYASE, PENTAETHYLENE GLYCOL, PYRUVIC ACID
Authors:Campeotto, I, Carr, S.B, Trinh, C.H, Nelson, A.S, Berry, A, Phillips, S.E.V, Pearson, A.R.
Deposit date:2009-06-11
Release date:2009-12-01
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (1.45 Å)
Cite:Structure of an Escherichia coli N-acetyl-D-neuraminic acid lyase mutant, E192N, in complex with pyruvate at 1.45 angstrom resolution.
Acta Crystallogr. Sect. F Struct. Biol. Cryst. Commun., 65, 2009
1B57
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BU of 1b57 by Molmil
CLASS II FRUCTOSE-1,6-BISPHOSPHATE ALDOLASE IN COMPLEX WITH PHOSPHOGLYCOLOHYDROXAMATE
Descriptor: CHLORIDE ION, PHOSPHOGLYCOLOHYDROXAMIC ACID, PROTEIN (FRUCTOSE-BISPHOSPHATE ALDOLASE II), ...
Authors:Hall, D.R, Hunter, W.N.
Deposit date:1999-01-12
Release date:2000-01-07
Last modified:2023-08-09
Method:X-RAY DIFFRACTION (2 Å)
Cite:The crystal structure of Escherichia coli class II fructose-1, 6-bisphosphate aldolase in complex with phosphoglycolohydroxamate reveals details of mechanism and specificity.
J.Mol.Biol., 287, 1999
1GES
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BU of 1ges by Molmil
ANATOMY OF AN ENGINEERED NAD-BINDING SITE
Descriptor: FLAVIN-ADENINE DINUCLEOTIDE, GLUTATHIONE REDUCTASE
Authors:Mittl, P.R.E, Schulz, G.E.
Deposit date:1994-01-18
Release date:1994-11-01
Last modified:2021-11-03
Method:X-RAY DIFFRACTION (1.74 Å)
Cite:Anatomy of an engineered NAD-binding site.
Protein Sci., 3, 1994
1GEU
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BU of 1geu by Molmil
ANATOMY OF AN ENGINEERED NAD-BINDING SITE
Descriptor: FLAVIN-ADENINE DINUCLEOTIDE, GLUTATHIONE REDUCTASE, NICOTINAMIDE-ADENINE-DINUCLEOTIDE
Authors:Mittl, P.R.E, Schulz, G.E.
Deposit date:1994-01-18
Release date:1994-11-01
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Anatomy of an engineered NAD-binding site.
Protein Sci., 3, 1994
1ZEN
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BU of 1zen by Molmil
CLASS II FRUCTOSE-1,6-BISPHOSPHATE ALDOLASE
Descriptor: CLASS II FRUCTOSE-1,6-BISPHOSPHATE ALDOLASE, ZINC ION
Authors:Cooper, S.J, Leonard, G.A, Hunter, W.N.
Deposit date:1996-07-08
Release date:1997-07-07
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:The crystal structure of a class II fructose-1,6-bisphosphate aldolase shows a novel binuclear metal-binding active site embedded in a familiar fold.
Structure, 4, 1996
1GET
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BU of 1get by Molmil
ANATOMY OF AN ENGINEERED NAD-BINDING SITE
Descriptor: FLAVIN-ADENINE DINUCLEOTIDE, GLUTATHIONE REDUCTASE, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
Authors:Mittl, P.R.E, Schulz, G.E.
Deposit date:1994-01-18
Release date:1994-11-01
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2 Å)
Cite:Anatomy of an engineered NAD-binding site.
Protein Sci., 3, 1994
7B21
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BU of 7b21 by Molmil
The X183 domain from Cellvibrio japonicus Cbp2D
Descriptor: 1,2-ETHANEDIOL, Carbohydrate binding protein, putative, ...
Authors:Branch, J, Hemsworth, G.R.
Deposit date:2020-11-25
Release date:2021-07-21
Last modified:2021-09-29
Method:X-RAY DIFFRACTION (1.2 Å)
Cite:C-type cytochrome-initiated reduction of bacterial lytic polysaccharide monooxygenases.
Biochem.J., 478, 2021

 

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