3Q1E
 
 | | Crystal structure of Y116T/I16A double mutant of 5-hydroxyisourate hydrolase in complex with T4 | | Descriptor: | 3,5,3',5'-TETRAIODO-L-THYRONINE, 5-hydroxyisourate hydrolase | | Authors: | Cendron, L, Ramazzina, I, Percudani, R, Zanotti, G, Berni, R. | | Deposit date: | 2010-12-17 | | Release date: | 2011-05-04 | | Last modified: | 2023-11-15 | | Method: | X-RAY DIFFRACTION (1.95 Å) | | Cite: | Probing the evolution of hydroxyisourate hydrolase into transthyretin through active-site redesign.
J.Mol.Biol., 409, 2011
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1TYR
 | | TRANSTHYRETIN COMPLEX WITH RETINOIC ACID | | Descriptor: | (9cis)-retinoic acid, TRANSTHYRETIN | | Authors: | Zanotti, G, D'Acunto, M.R, Malpeli, G, Folli, C, Berni, R. | | Deposit date: | 1995-05-12 | | Release date: | 1995-09-15 | | Last modified: | 2017-11-29 | | Method: | X-RAY DIFFRACTION (1.8 Å) | | Cite: | Crystal structure of the transthyretin--retinoic-acid complex
Eur.J.Biochem., 234, 1995
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1BOH
 | | SULFUR-SUBSTITUTED RHODANESE (ORTHORHOMBIC FORM) | | Descriptor: | RHODANESE | | Authors: | Gliubich, F, Berni, R, Cianci, M, Trevino, R.J, Horowitz, P.M, Zanotti, G. | | Deposit date: | 1998-08-04 | | Release date: | 1999-04-27 | | Last modified: | 2023-08-09 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | NH2-terminal sequence truncation decreases the stability of bovine rhodanese, minimally perturbs its crystal structure, and enhances interaction with GroEL under native conditions.
J.Biol.Chem., 274, 1999
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1BOI
 | | N-TERMINALLY TRUNCATED RHODANESE | | Descriptor: | RHODANESE | | Authors: | Gliubich, F, Berni, R, Cianci, M, Trevino, R.J, Horowitz, P.M, Zanotti, G. | | Deposit date: | 1998-08-04 | | Release date: | 1999-04-27 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (2.2 Å) | | Cite: | NH2-terminal sequence truncation decreases the stability of bovine rhodanese, minimally perturbs its crystal structure, and enhances interaction with GroEL under native conditions.
J.Biol.Chem., 274, 1999
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1AQB
 | | RETINOL-BINDING PROTEIN (RBP) FROM PIG PLASMA | | Descriptor: | CADMIUM ION, RETINOL, RETINOL-BINDING PROTEIN | | Authors: | Zanotti, G, Panzalorto, M, Marcato, A, Malpeli, G, Folli, C, Berni, R. | | Deposit date: | 1997-07-28 | | Release date: | 1998-01-28 | | Last modified: | 2023-08-02 | | Method: | X-RAY DIFFRACTION (1.65 Å) | | Cite: | Structure of pig plasma retinol-binding protein at 1.65 A resolution.
Acta Crystallogr.,Sect.D, 54, 1998
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4WO0
 | | Crystal structure of transthyretin in complex with apigenin | | Descriptor: | 5,7-dihydroxy-2-(4-hydroxyphenyl)-4H-chromen-4-one, Transthyretin | | Authors: | Zanotti, G, Cianci, M, Folli, C, Berni, R. | | Deposit date: | 2014-10-15 | | Release date: | 2015-08-05 | | Last modified: | 2024-01-10 | | Method: | X-RAY DIFFRACTION (1.339 Å) | | Cite: | Structural evidence for asymmetric ligand binding to transthyretin.
Acta Crystallogr.,Sect.D, 71, 2015
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4WNJ
 | | Crystal structure of Transthyretin-quercetin complex | | Descriptor: | 3,5,7,3',4'-PENTAHYDROXYFLAVONE, DIMETHYL SULFOXIDE, Transthyretin | | Authors: | Zanotti, G, Cianci, M, Berni, R, Folli, C. | | Deposit date: | 2014-10-13 | | Release date: | 2015-08-05 | | Last modified: | 2024-01-10 | | Method: | X-RAY DIFFRACTION (1.398 Å) | | Cite: | Structural evidence for asymmetric ligand binding to transthyretin.
Acta Crystallogr.,Sect.D, 71, 2015
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4WNS
 | | Crystal structure of Transthyretin complexed with pterostilbene | | Descriptor: | DIMETHYL SULFOXIDE, Pterostilbene, SULFATE ION, ... | | Authors: | Zanotti, G, Cianci, M, Folli, C, Berni, R. | | Deposit date: | 2014-10-14 | | Release date: | 2015-08-05 | | Last modified: | 2024-01-10 | | Method: | X-RAY DIFFRACTION (1.399 Å) | | Cite: | Structural evidence for asymmetric ligand binding to transthyretin.
Acta Crystallogr.,Sect.D, 71, 2015
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3IWV
 | | Crystal structure of Y116T mutant of 5-HYDROXYISOURATE HYDROLASE (TRP) | | Descriptor: | 5-hydroxyisourate hydrolase | | Authors: | Cendron, L, Ramazzina, I, Berni, R, Percudani, R, Zanotti, G. | | Deposit date: | 2009-09-03 | | Release date: | 2010-09-01 | | Last modified: | 2023-11-01 | | Method: | X-RAY DIFFRACTION (1.68 Å) | | Cite: | Probing the evolution of hydroxyisourate hydrolase into transthyretin through active-site redesign.
J.Mol.Biol., 409, 2011
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3IWU
 | | Crystal structure of Y116T/I16A double mutant of 5-hydroxyisourate hydrolase | | Descriptor: | 5-hydroxyisourate hydrolase | | Authors: | Cendron, L, Ramazzina, I, Berni, R, Percudani, R, Zanotti, G. | | Deposit date: | 2009-09-03 | | Release date: | 2010-09-01 | | Last modified: | 2023-11-01 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | Probing the evolution of hydroxyisourate hydrolase into transthyretin through active-site redesign.
J.Mol.Biol., 409, 2011
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4I89
 | | Crystal structure of transthyretin in complex with diflunisal at acidic pH | | Descriptor: | 5-(2,4-DIFLUOROPHENYL)-2-HYDROXY-BENZOIC ACID, Transthyretin | | Authors: | Zanotti, G, Cendron, L, Folli, C, Florio, P, Imbimbo, B.P, Berni, R. | | Deposit date: | 2012-12-03 | | Release date: | 2013-06-19 | | Last modified: | 2023-09-20 | | Method: | X-RAY DIFFRACTION (1.69 Å) | | Cite: | Structural evidence for native state stabilization of a conformationally labile amyloidogenic transthyretin variant by fibrillogenesis inhibitors.
Febs Lett., 587, 2013
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4I87
 | | Crystal structure of TTR variant I84S in complex with CHF5074 at acidic pH | | Descriptor: | 1-(3',4'-dichloro-2-fluorobiphenyl-4-yl)cyclopropanecarboxylic acid, Transthyretin | | Authors: | Zanotti, G, Cendron, L, Folli, C, Florio, P, Imbimbo, B.P, Berni, R. | | Deposit date: | 2012-12-03 | | Release date: | 2013-06-19 | | Last modified: | 2023-09-20 | | Method: | X-RAY DIFFRACTION (1.69 Å) | | Cite: | Structural evidence for native state stabilization of a conformationally labile amyloidogenic transthyretin variant by fibrillogenesis inhibitors.
Febs Lett., 587, 2013
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4I85
 | | Crystal structure of transthyretin in complex with CHF5074 at neutral pH | | Descriptor: | 1-(3',4'-dichloro-2-fluorobiphenyl-4-yl)cyclopropanecarboxylic acid, Transthyretin | | Authors: | Zanotti, G, Cendron, L, Folli, C, Florio, P, Imbimbo, B.P, Berni, R. | | Deposit date: | 2012-12-03 | | Release date: | 2013-06-19 | | Last modified: | 2023-09-20 | | Method: | X-RAY DIFFRACTION (1.67 Å) | | Cite: | Structural evidence for native state stabilization of a conformationally labile amyloidogenic transthyretin variant by fibrillogenesis inhibitors.
Febs Lett., 587, 2013
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4ALO
 | | STRUCTURE AND PROPERTIES OF H1 CRUSTACYANIN FROM LOBSTER HOMARUS AMERICANUS | | Descriptor: | (4S)-2-METHYL-2,4-PENTANEDIOL, H1 APOCRUSTACYANIN, SODIUM ION, ... | | Authors: | Ferrari, M, Folli, C, Pincolini, E, Mcclintock, T.S, Roessle, M, Berni, R, Cianci, M. | | Deposit date: | 2012-03-05 | | Release date: | 2012-08-08 | | Last modified: | 2023-12-20 | | Method: | X-RAY DIFFRACTION (2.37 Å) | | Cite: | Structural Characterization of Recombinant Crustacyanin Subunits from the Lobster Homarus Americanus.
Acta Crystallogr.,Sect.F, 68, 2012
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1ERB
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1FEL
 | | CRYSTALLOGRAPHIC STUDIES ON COMPLEXES BETWEEN RETINOIDS AND PLASMA RETINOL-BINDING PROTEIN | | Descriptor: | N-(4-HYDROXYPHENYL)ALL-TRANS RETINAMIDE, RETINOL BINDING PROTEIN | | Authors: | Zanotti, G, Marcello, M, Malpeli, G, Sartori, G, Berni, R. | | Deposit date: | 1994-08-29 | | Release date: | 1994-11-01 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (1.8 Å) | | Cite: | Crystallographic studies on complexes between retinoids and plasma retinol-binding protein.
J.Biol.Chem., 269, 1994
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1FEM
 | | CRYSTALLOGRAPHIC STUDIES ON COMPLEXES BETWEEN RETINOIDS AND PLASMA RETINOL-BINDING PROTEIN | | Descriptor: | RETINOIC ACID, RETINOL BINDING PROTEIN | | Authors: | Zanotti, G, Marcello, M, Malpeli, G, Sartori, G, Berni, R. | | Deposit date: | 1994-08-29 | | Release date: | 1994-11-01 | | Last modified: | 2024-02-07 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | Crystallographic studies on complexes between retinoids and plasma retinol-binding protein.
J.Biol.Chem., 269, 1994
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1FEN
 | | CRYSTALLOGRAPHIC STUDIES ON COMPLEXES BETWEEN RETINOIDS AND PLASMA RETINOL-BINDING PROTEIN | | Descriptor: | ALL-TRANS AXEROPHTHENE, RETINOL BINDING PROTEIN | | Authors: | Zanotti, G, Marcello, M, Malpeli, G, Sartori, G, Berni, R. | | Deposit date: | 1994-08-29 | | Release date: | 1994-11-01 | | Last modified: | 2024-02-07 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | Crystallographic studies on complexes between retinoids and plasma retinol-binding protein.
J.Biol.Chem., 269, 1994
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3ISL
 | | Crystal structure of ureidoglycine-glyoxylate aminotransferase (pucG) from Bacillus subtilis | | Descriptor: | PYRIDOXAL-5'-PHOSPHATE, Purine catabolism protein pucG | | Authors: | Costa, R, Cendron, L, Ramazzina, I, Berni, R, Peracchi, A, Percudani, R, Zanotti, G. | | Deposit date: | 2009-08-26 | | Release date: | 2010-09-15 | | Last modified: | 2023-11-01 | | Method: | X-RAY DIFFRACTION (2.06 Å) | | Cite: | Amino acids from purines in GUT bacteria
To be Published
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5OQ0
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2H1X
 | | Crystal structure of 5-hydroxyisourate Hydrolase (formerly known as TRP, Transthyretin Related Protein) | | Descriptor: | 5-hydroxyisourate Hydrolase (formerly known as TRP, Transthyretin Related Protein) | | Authors: | Zanotti, G, Cendron, L, Folli, C, Ramazzina, I, Percudani, R, Berni, R. | | Deposit date: | 2006-05-17 | | Release date: | 2006-10-31 | | Last modified: | 2023-08-30 | | Method: | X-RAY DIFFRACTION (1.98 Å) | | Cite: | Structure of Zebra fish HIUase: Insights into Evolution of an Enzyme to a Hormone Transporter.
J.Mol.Biol., 363, 2006
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2H6U
 | | Crystal structure of 5-hydroxyisourate hydrolase (formerly known as TRP, transthyretin related protein) | | Descriptor: | 5-HYDROXYISOURATE HYDROLASE (FORMERLY KNOWN AS TRP, TRANSTHYRETIN RELATED PROTEIN) | | Authors: | Zanotti, G, Cendron, L, Folli, C, Ramazzina, I, Percudani, R, Berni, R. | | Deposit date: | 2006-06-01 | | Release date: | 2006-10-31 | | Last modified: | 2023-08-30 | | Method: | X-RAY DIFFRACTION (1.7 Å) | | Cite: | Structure of Zebra fish HIUase: Insights into Evolution of an Enzyme to a Hormone Transporter.
J.Mol.Biol., 363, 2006
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1IIU
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2B5S
 | | Crystal structure of peach Pru p3, the prototypic member of the family of plant non-specific lipid transfer protein pan-allergens | | Descriptor: | HEPTANE, LAURIC ACID, Non-specific lipid transfer protein, ... | | Authors: | Pasquato, N, Berni, R, Folli, C, Folloni, S, Cianci, M, Pantano, S, Helliwell, R.J, Zanotti, G. | | Deposit date: | 2005-09-29 | | Release date: | 2005-11-29 | | Last modified: | 2023-08-23 | | Method: | X-RAY DIFFRACTION (2.35 Å) | | Cite: | Crystal Structure of Peach Pru p 3, the Prototypic Member of the Family of Plant Non-specific Lipid Transfer Protein Pan-allergens
J.Mol.Biol., 356, 2006
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2O70
 | | Structure of OHCU decarboxylase from zebrafish | | Descriptor: | OHCU decarboxylase | | Authors: | Cendron, L, Berni, R, Folli, C, Ramazzina, I, Percudani, R, Zanotti, G. | | Deposit date: | 2006-12-09 | | Release date: | 2007-04-10 | | Last modified: | 2023-12-27 | | Method: | X-RAY DIFFRACTION (1.8 Å) | | Cite: | The structure of 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase provides insights into the mechanism of uric acid degradation.
J.Biol.Chem., 282, 2007
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