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1IGR
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BU of 1igr by Molmil
Type 1 Insulin-like growth factor receptor (DOMAINS 1-3)
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, INSULIN-LIKE GROWTH FACTOR RECEPTOR 1, ...
Authors:Garrett, T.P.J, Mckern, N.M, Lou, M, Frenkel, M.J, Bentley, J.D, Lovrecz, G.O, Elleman, T.C, Cosgrove, L.J, Ward, C.W.
Deposit date:1998-09-28
Release date:1999-09-27
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Crystal structure of the first three domains of the type-1 insulin-like growth factor receptor.
Nature, 394, 1998
3KR3
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BU of 3kr3 by Molmil
Crystal structure of IGF-II antibody complex
Descriptor: 1,2-ETHANEDIOL, Insulin-like growth factor II, antibody-Fab (heavy chain), ...
Authors:Peat, T.S, Newman, J, Adams, T.E.
Deposit date:2009-11-17
Release date:2010-06-16
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:A human monoclonal antibody against insulin-like growth factor-II blocks the growth of human hepatocellular carcinoma cell lines in vitro and in vivo.
Mol.Cancer Ther., 9, 2010
2HR7
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BU of 2hr7 by Molmil
Insulin receptor (domains 1-3)
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Garrett, T.P.J, Ward, C.W.
Deposit date:2006-07-19
Release date:2006-08-15
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.32 Å)
Cite:The first three domains of the insulin receptor differ structurally from the insulin-like growth factor 1 receptor in the regions governing ligand specificity.
Proc.Natl.Acad.Sci.Usa, 103, 2006

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