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1MHM
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Crystal structure of S-adenosylmethionine decarboxylase from potato
Descriptor: S-adenosylmethionine decarboxylase
Authors:Bennett, E.M, Ekstrom, J.L, Pegg, A.E, Ealick, S.E.
Deposit date:2002-08-20
Release date:2002-12-11
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Monomeric S-Adenosylmethionine Decarboxylase from Plants Provides an Alternative to Putrescine Stimulation
Biochemistry, 41, 2002
1PW7
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Crystal Structure of E. coli purine nucleoside phosphorylase complexed with 9-beta-D-arabinofuranosyladenine and sulfate/phosphate
Descriptor: 2-(6-AMINO-PURIN-9-YL)-5-HYDROXYMETHYL-TETRAHYDRO-FURAN-3,4-DIOL, PHOSPHATE ION, Purine nucleoside phosphorylase DeoD-type
Authors:Bennett, E.M, Li, C, Allan, P.W, Parker, W.B, Ealick, S.E.
Deposit date:2003-06-30
Release date:2003-11-25
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural basis for substrate specificity of Escherichia coli purine nucleoside phosphorylase.
J.Biol.Chem., 278, 2003
1PK7
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Crystal Structure of E. coli purine nucleoside phosphorylase complexed with adenosine and sulfate/phosphate
Descriptor: ADENOSINE, PHOSPHATE ION, Purine nucleoside phosphorylase DeoD-type
Authors:Bennett, E.M, Li, C, Allan, P.W, Parker, W.B, Ealick, S.E.
Deposit date:2003-06-05
Release date:2003-11-25
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structural basis for substrate specificity of Escherichia coli purine nucleoside phosphorylase.
J.Biol.Chem., 278, 2003
1PK9
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Crystal Structure of E. coli purine nucleoside phosphorylase complexed with 2-fluoroadenosine and sulfate/phosphate
Descriptor: 2-(6-AMINO-2-FLUORO-PURIN-9-YL)-5-HYDROXYMETHYL-TETRAHYDRO-FURAN-3,4-DIOL, PHOSPHATE ION, Purine nucleoside phosphorylase DeoD-type
Authors:Bennett, E.M, Li, C, Allan, P.W, Parker, W.B, Ealick, S.E.
Deposit date:2003-06-05
Release date:2003-11-25
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structural basis for substrate specificity of Escherichia coli purine nucleoside phosphorylase.
J.Biol.Chem., 278, 2003
1PKE
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Crystal Structure of E. coli purine nucleoside phosphorylase complexed with 2-fluoro-2'-deoxyadenosine and sulfate/phosphate
Descriptor: 5-(6-AMINO-2-FLUORO-PURIN-9-YL)-2-HYDROXYMETHYL-TETRAHYDRO-FURAN-3-OL, PHOSPHATE ION, Purine nucleoside phosphorylase DeoD-type
Authors:Bennett, E.M, Li, C, Allan, P.W, Parker, W.B, Ealick, S.E.
Deposit date:2003-06-05
Release date:2003-11-25
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structural basis for substrate specificity of Escherichia coli purine nucleoside phosphorylase.
J.Biol.Chem., 278, 2003
1PR4
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BU of 1pr4 by Molmil
Escherichia coli Purine Nucleoside Phosphorylase Complexed with 9-beta-D-ribofuranosyl-6-methylthiopurine and Phosphate/Sulfate
Descriptor: 2-HYDROXYMETHYL-5-(6-METHYLSULFANYL-PURIN-9-YL)-TETRAHYDRO-FURAN-3,4-DIOL, PHOSPHATE ION, Purine nucleoside phosphorylase DeoD-type
Authors:Bennett, E.M, Li, C, Allan, P.W, Parker, W.B, Ealick, S.E.
Deposit date:2003-06-19
Release date:2003-11-25
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Structural basis for substrate specificity of Escherichia coli purine nucleoside phosphorylase.
J.Biol.Chem., 278, 2003
1PR1
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Escherichia coli Purine Nucleoside Phosphorylase Complexed with Formycin B and Phosphate/Sulfate
Descriptor: FORMYCIN B, PHOSPHATE ION, Purine nucleoside phosphorylase
Authors:Bennett, E.M, Li, C, Allan, P.W, Parker, W.B, Ealick, S.E.
Deposit date:2003-06-19
Release date:2003-11-25
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structural basis for substrate specificity of Escherichia coli purine nucleoside phosphorylase.
J.Biol.Chem., 278, 2003
1PR6
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Escherichia coli Purine Nucleoside Phosphorylase Complexed with 9-beta-D-xylofuranosyladenine and Phosphate/Sulfate
Descriptor: 2-(6-AMINO-OCTAHYDRO-PURIN-9-YL)-5-HYDROXYMETHYL-TETRAHYDRO-FURAN-3,4-DIOL, PHOSPHATE ION, Purine nucleoside phosphorylase DeoD-type
Authors:Bennett, E.M, Li, C, Allan, P.W, Parker, W.B, Ealick, S.E.
Deposit date:2003-06-19
Release date:2003-11-25
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structural basis for substrate specificity of Escherichia coli purine nucleoside phosphorylase.
J.Biol.Chem., 278, 2003
1PR5
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Escherichia coli Purine Nucleoside Phosphorylase Complexed with 7-deazaadenosine and Phosphate/Sulfate
Descriptor: '2-(4-AMINO-PYRROLO[2,3-D]PYRIMIDIN-7-YL)-5-HYDROXYMETHYL-TETRAHYDRO-FURAN-3,4-DIOL, PHOSPHATE ION, Purine nucleoside phosphorylase DeoD-type
Authors:Bennett, E.M, Li, C, Allan, P.W, Parker, W.B, Ealick, S.E.
Deposit date:2003-06-19
Release date:2003-11-25
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structural basis for substrate specificity of Escherichia coli purine nucleoside phosphorylase.
J.Biol.Chem., 278, 2003
1PR0
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BU of 1pr0 by Molmil
Escherichia coli Purine Nucleoside Phosphorylase Complexed with Inosine and Phosphate/Sulfate
Descriptor: INOSINE, PHOSPHATE ION, Purine nucleoside phosphorylase DeoD-type
Authors:Bennett, E.M, Li, C, Allan, P.W, Parker, W.B, Ealick, S.E.
Deposit date:2003-06-19
Release date:2003-11-25
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structural basis for substrate specificity of Escherichia coli purine nucleoside phosphorylase.
J.Biol.Chem., 278, 2003
1PR2
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BU of 1pr2 by Molmil
Escherichia coli Purine Nucleoside Phosphorylase Complexed with 9-beta-D-[2-deoxyribofuranosyl]-6-methylpurine and Phosphate/Sulfate
Descriptor: 9-(2-DEOXY-BETA-D-RIBOFURANOSYL)-6-METHYLPURINE, PHOSPHATE ION, Purine nucleoside phosphorylase DeoD-type
Authors:Bennett, E.M, Li, C, Allan, P.W, Parker, W.B, Ealick, S.E.
Deposit date:2003-06-19
Release date:2003-11-25
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structural basis for substrate specificity of Escherichia coli purine nucleoside phosphorylase.
J.Biol.Chem., 278, 2003
1OV6
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M64V PNP + ALLO
Descriptor: 9-(6-DEOXY-BETA-D-ALLOFURANOSYL)-6-METHYLPURINE, PHOSPHATE ION, Purine nucleoside phosphorylase
Authors:Ealick, S.E, Bennett, E.M, Anand, R, Secrist, J.A, Parker, P.W, Hassan, A.E, Allan, P.W, McPherson, D.T, Sorscher, E.J.
Deposit date:2003-03-25
Release date:2004-02-17
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Designer gene therapy using an Escherichia coli purine nucleoside phosphorylase/prodrug system.
Chem.Biol., 10, 2003
1OVG
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BU of 1ovg by Molmil
M64V PNP +MePdr
Descriptor: 9-(2-DEOXY-BETA-D-RIBOFURANOSYL)-6-METHYLPURINE, PHOSPHATE ION, Purine nucleoside phosphorylase
Authors:Ealick, S.E, Bennett, E.M, Anand, R, Secrist, J.A, Parker, P.W, Hassan, A.E, Allan, P.W, McPherson, D.T, Sorscher, E.J.
Deposit date:2003-03-26
Release date:2004-02-17
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Designer gene therapy using an Escherichia coli purine nucleoside phosphorylase/prodrug system.
Chem.Biol., 10, 2003
1OUM
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BU of 1oum by Molmil
M64V PNP +Talo
Descriptor: 9-(6-DEOXY-ALPHA-L-TALOFURANOSYL)-6-METHYLPURINE, PHOSPHATE ION, Purine nucleoside phosphorylase
Authors:Ealick, S.E, Bennett, E.M, Anand, R, Secrist, J.A, Parker, W.B, Hassan, A.E, Allan, P.W, McPherson, D.T, Sorscher, E.J.
Deposit date:2003-03-24
Release date:2004-02-17
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Designer gene therapy using an Escherichia coli purine nucleoside phosphorylase/prodrug system.
Chem.Biol., 10, 2003
1OU4
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Native PNP +Talo
Descriptor: 6-METHYLPURINE, PHOSPHATE ION, Purine nucleoside phosphorylase
Authors:Ealick, S.E, Bennett, E.M, Anand, R, Secrist, J.A, Parker, W.B, Hassan, A.E, Allan, P.W, McPherson, D.T, Sorscher, E.J.
Deposit date:2003-03-24
Release date:2004-02-17
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Designer gene therapy using an Escherichia coli purine nucleoside phosphorylase/prodrug system.
Chem.Biol., 10, 2003
1OTX
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BU of 1otx by Molmil
Purine Nucleoside Phosphorylase M64V mutant
Descriptor: PHOSPHATE ION, Purine nucleoside phosphorylase
Authors:Ealick, S.E, Bennett, E.M, Anand, R, Secrist, J.A, Parker, W.B, Hassan, A.E, Allan, P.W, McPherson, D.T, Sorscher, E.J.
Deposit date:2003-03-23
Release date:2004-02-17
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Designer gene therapy using an Escherichia coli purine nucleoside phosphorylase/prodrug system.
Chem.Biol., 10, 2003
1OTY
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BU of 1oty by Molmil
Native PNP +ALLO
Descriptor: 6-METHYLPURINE, PHOSPHATE ION, Purine nucleoside phosphorylase
Authors:Ealick, S.E, Bennett, E.M, Anand, R, Secrist, J.A, Parker, W.B, Hassan, A.E, Allan, P.W, McPherson, D.T, Sorscher, E.J.
Deposit date:2003-03-23
Release date:2004-02-17
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Designer gene therapy using an Escherichia coli purine nucleoside phosphorylase/prodrug system.
Chem.Biol., 10, 2003
4FUL
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BU of 4ful by Molmil
PI3 Kinase Gamma bound to a pyrmidine inhibitor
Descriptor: 4-({4-[3-(piperidin-1-ylcarbonyl)phenyl]pyrimidin-2-yl}amino)benzenesulfonamide, Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform
Authors:Gopalsamy, A, Bennett, E.M, Shi, M, Zhang, W.G, Bard, J, Yu, K.
Deposit date:2012-06-28
Release date:2012-10-17
Last modified:2012-10-31
Method:X-RAY DIFFRACTION (2.47 Å)
Cite:Identification of pyrimidine derivatives as hSMG-1 inhibitors.
Bioorg.Med.Chem.Lett., 22, 2012
1T4A
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BU of 1t4a by Molmil
Structure of B. Subtilis PurS C2 Crystal Form
Descriptor: PurS
Authors:Anand, R, Hoskins, A.A, Bennett, E.M, Sintchak, M.D, Stubbe, J, Ealick, S.E.
Deposit date:2004-04-28
Release date:2004-09-14
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:A model for the Bacillus subtilis formylglycinamide ribonucleotide amidotransferase multiprotein complex.
Biochemistry, 43, 2004
1JXH
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BU of 1jxh by Molmil
4-Amino-5-hydroxymethyl-2-methylpyrimidine Phosphate Kinase from Salmonella typhimurium
Descriptor: PHOSPHOMETHYLPYRIMIDINE KINASE, SULFATE ION
Authors:Cheng, G, Bennett, E.M, Begley, T.P, Ealick, S.E.
Deposit date:2001-09-07
Release date:2002-02-27
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Crystal structure of 4-amino-5-hydroxymethyl-2-methylpyrimidine phosphate kinase from Salmonella typhimurium at 2.3 A resolution.
Structure, 10, 2002
1JXI
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4-Amino-5-hydroxymethyl-2-methylpyrimidine Phosphate Kinase from Salmonella typhimurium complexed with 4-Amino-5-hydroxymethyl-2-methylpyrimidine
Descriptor: 4-AMINO-5-HYDROXYMETHYL-2-METHYLPYRIMIDINE, PHOSPHOMETHYLPYRIMIDINE KINASE, SULFATE ION
Authors:Cheng, G, Bennett, E.M, Begley, T.P, Ealick, S.E.
Deposit date:2001-09-07
Release date:2002-02-27
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.64 Å)
Cite:Crystal structure of 4-amino-5-hydroxymethyl-2-methylpyrimidine phosphate kinase from Salmonella typhimurium at 2.3 A resolution.
Structure, 10, 2002
1MSV
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BU of 1msv by Molmil
The S68A S-adenosylmethionine decarboxylase proenzyme processing mutant.
Descriptor: 1,4-DIAMINOBUTANE, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, S-adenosylmethionine decarboxylase proenzyme
Authors:Tolbert, W.D, Zhang, Y, Bennett, E.M, Cottet, S.E, Ekstrom, J.L, Pegg, A.E, Ealick, S.E.
Deposit date:2002-09-19
Release date:2003-03-11
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Mechanism of Human S-Adenosylmethionine Decarboxylase Proenzyme Processing as Revealed by the Structure of the S68A Mutant.
Biochemistry, 42, 2003
1R9G
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BU of 1r9g by Molmil
Three-dimensional Structure of YaaE from Bacillus subtilis
Descriptor: Hypothetical protein yaaE
Authors:Bauer, J.A, Bennett, E.M, Begley, T.P, Ealick, S.E.
Deposit date:2003-10-29
Release date:2004-01-27
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Three-dimensional Structure of YaaE from Bacillus subtilis, a Glutaminase Implicated in Pyridoxal-5'-phosphate Biosynthesis.
J.Biol.Chem., 279, 2004
1TWJ
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BU of 1twj by Molmil
Crystal Structure of B. subtilis PurS P21 Crystal Form
Descriptor: Hypothetical UPF0062 protein yexA
Authors:Anand, R, Ealick, S.E, Hoskins, A.A, Stubbe, J.
Deposit date:2004-07-01
Release date:2004-08-31
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:A Model for the Bacillus subtilis Formylglycinamide Ribonucleotide Amidotransferase Multiprotein Complex
Biochemistry, 43, 2004
7KQ7
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Crystal structure of IL21R in complex with an antibody Fab fragment
Descriptor: Antibody heavy chain, Antibody light chain, Interleukin-21 receptor
Authors:Mosyak, L, Svenson, K.
Deposit date:2020-11-13
Release date:2021-04-07
Last modified:2021-04-14
Method:X-RAY DIFFRACTION (2.203 Å)
Cite:Combining random mutagenesis, structure-guided design and next-generation sequencing to mitigate polyreactivity of an anti-IL-21R antibody.
Mabs, 13, 2021

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