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1KFD
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CRYSTAL STRUCTURES OF THE KLENOW FRAGMENT OF DNA POLYMERASE I COMPLEXED WITH DEOXYNUCLEOSIDE TRIPHOSPHATE AND PYROPHOSPHATE
Descriptor:DNA POLYMERASE I KLENOW FRAGMENT, CYTIDINE-5'-TRIPHOSPHATE
Authors:Beese, L.S., Friedman, J.M., Steitz, T.A.
Deposit date:1993-09-23
Release date:1994-06-22
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3.9 Å)
Cite:Crystal structures of the Klenow fragment of DNA polymerase I complexed with deoxynucleoside triphosphate and pyrophosphate.
Biochemistry, 32, 1993
1KLN
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DNA POLYMERASE I KLENOW FRAGMENT (E.C.2.7.7.7) MUTANT/DNA COMPLEX
Descriptor:DNA (5'-D(*GP*CP*CP*TP*CP*GP*CP*GP*GP*CP*GP*GP*C)-3'), DNA (5'-D(*GP*CP*CP*GP*CP*GP*AP*GP*GP*C)-3'), PROTEIN (DNA POLYMERASE I KLENOW FRAGMENT (E.C.2.7.7.7)), ...
Authors:Beese, L.S., Derbyshire, V., Steitz, T.A.
Deposit date:1994-05-24
Release date:1994-11-30
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Structure of DNA polymerase I Klenow fragment bound to duplex DNA.
Science, 260, 1993
1FT2
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CO-CRYSTAL STRUCTURE OF PROTEIN FARNESYLTRANSFERASE COMPLEXED WITH A FARNESYL DIPHOSPHATE SUBSTRATE
Descriptor:PROTEIN FARNESYLTRANSFERASE, ZINC ION, FARNESYL DIPHOSPHATE
Authors:Beese, L.S., Casey, P.J., Long, S.B.
Deposit date:1998-06-02
Release date:1998-11-04
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3.4 Å)
Cite:Cocrystal structure of protein farnesyltransferase complexed with a farnesyl diphosphate substrate.
Biochemistry, 37, 1998
1FT1
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CRYSTAL STRUCTURE OF PROTEIN FARNESYLTRANSFERASE AT 2.25 ANGSTROMS RESOLUTION
Descriptor:PROTEIN FARNESYLTRANSFERASE, ZINC ION
Authors:Beese, L.S., Park, H.-W.
Deposit date:1997-03-17
Release date:1998-03-18
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:Crystal structure of protein farnesyltransferase at 2.25 angstrom resolution.
Science, 275, 1997
1KZO
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PROTEIN FARNESYLTRANSFERASE COMPLEXED WITH FARNESYLATED K-RAS4B PEPTIDE PRODUCT AND FARNESYL DIPHOSPHATE SUBSTRATE BOUND SIMULTANEOUSLY
Descriptor:Protein Farnesyltransferase alpha subunit, Protein Farnesyltransferase beta subunit, Farnesylated K-Ras4B peptide product, ...
Authors:Long, S.B., Casey, P.J., Beese, L.S.
Deposit date:2002-02-07
Release date:2002-10-16
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:The Reaction Path of Protein Farnesyltransferase at Atomic Resolution
Nature, 419, 2002
1KZP
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PROTEIN FARNESYLTRANSFERASE COMPLEXED WITH A FARNESYLATED K-RAS4B PEPTIDE PRODUCT
Descriptor:Protein Farnesyltransferase alpha subunit, Protein Farnesyltransferase beta subunit, Farnesylated K-Ras4B peptide product, ...
Authors:Long, S.B., Casey, P.J., Beese, L.S.
Deposit date:2002-02-07
Release date:2002-10-16
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Reaction path of protein farnesyltransferase at atomic resolution
Nature, 419, 2002
1NJW
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GUANINE-THYMINE MISMATCH AT THE POLYMERASE ACTIVE SITE
Descriptor:DNA PRIMER STRAND, DNA TEMPLATE STRAND, DNA POLYMERASE I, ...
Authors:Johnson, S.J., Beese, L.S.
Deposit date:2003-01-02
Release date:2004-03-30
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structures of mismatch replication errors observed in a DNA polymerase.
Cell(Cambridge,Mass.), 116, 2004
1NJX
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THYMINE-GUANINE MISMATCH AT THE POLYMERASE ACTIVE SITE
Descriptor:DNA PRIMER STRAND, DNA TEMPLATE STRAND, DNA POLYMERASE I, ...
Authors:Johnson, S.J., Beese, L.S.
Deposit date:2003-01-02
Release date:2004-03-30
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:Structures of mismatch replication errors observed in a DNA polymerase.
Cell(Cambridge,Mass.), 116, 2004
1NJY
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THYMINE-THYMINE MISMATCH AT THE POLYMERASE ACTIVE SITE
Descriptor:DNA PRIMER STRAND, DNA TEMPLATE STRAND, DNA POLYMERASE I, ...
Authors:Johnson, S.J., Beese, L.S.
Deposit date:2003-01-02
Release date:2004-03-30
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structures of mismatch replication errors observed in a DNA polymerase.
Cell(Cambridge,Mass.), 116, 2004
1NJZ
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CYTOSINE-THYMINE MISMATCH AT THE POLYMERASE ACTIVE SITE
Descriptor:DNA PRIMER STRAND, DNA TEMPLATE STRAND, DNA POLYMERASE I, ...
Authors:Johnson, S.J., Beese, L.S.
Deposit date:2003-01-02
Release date:2004-03-30
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structures of mismatch replication errors observed in a DNA polymerase.
Cell(Cambridge,Mass.), 116, 2004
1NK0
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ADENINE-GUANINE MISMATCH AT THE POLYMERASE ACTIVE SITE
Descriptor:DNA PRIMER STRAND, DNA TEMPLATE STRAND, DNA POLYMERASE I, ...
Authors:Johnson, S.J., Beese, L.S.
Deposit date:2003-01-02
Release date:2004-03-30
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Structures of mismatch replication errors observed in a DNA polymerase.
Cell(Cambridge,Mass.), 116, 2004
1NK4
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GUANINE-GUANINE MISMATCH AT THE POLYMERASE ACTIVE SITE
Descriptor:DNA PRIMER STRAND, DNA TEMPLATE STRAND, DNA POLYMERASE I, ...
Authors:Johnson, S.J., Beese, L.S.
Deposit date:2003-01-02
Release date:2004-03-30
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Structures of mismatch replication errors observed in a DNA polymerase.
Cell(Cambridge,Mass.), 116, 2004
1NK5
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ADENINE-ADENINE MISMATCH AT THE POLYMERASE ACTIVE SITE
Descriptor:DNA PRIMER STRAND, DNA TEMPLATE STRAND, DNA POLYMERASE I, ...
Authors:Johnson, S.J., Beese, L.S.
Deposit date:2003-01-02
Release date:2004-03-30
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structures of mismatch replication errors observed in a DNA polymerase.
Cell(Cambridge,Mass.), 116, 2004
1NK6
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CYTOSINE-CYTOSINE MISMATCH AT THE POLYMERASE ACTIVE SITE
Descriptor:DNA PRIMER STRAND, DNA TEMPLATE STRAND, DNA POLYMERASE I, ...
Authors:Johnson, S.J., Beese, L.S.
Deposit date:2003-01-02
Release date:2004-03-30
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structures of mismatch replication errors observed in a DNA polymerase.
Cell(Cambridge,Mass.), 116, 2004
1NK7
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GUANINE-ADENINE MISMATCH AT THE POLYMERASE ACTIVE SITE
Descriptor:DNA PRIMER STRAND, DNA TEMPLATE STRAND, DNA POLYMERASE I, ...
Authors:Johnson, S.J., Beese, L.S.
Deposit date:2003-01-02
Release date:2004-03-30
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structures of mismatch replication errors observed in a DNA polymerase.
Cell(Cambridge,Mass.), 116, 2004
1NK8
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A BACILLUS DNA POLYMERASE I PRODUCT COMPLEX BOUND TO A GUANINE-THYMINE MISMATCH AFTER A SINGLE ROUND OF PRIMER EXTENSION, FOLLOWING INCORPORATION OF DCTP.
Descriptor:DNA PRIMER STRAND, DNA TEMPLATE STRAND, DNA POLYMERASE I, ...
Authors:Johnson, S.J., Beese, L.S.
Deposit date:2003-01-02
Release date:2004-03-30
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structures of mismatch replication errors observed in a DNA polymerase.
Cell(Cambridge,Mass.), 116, 2004
1NK9
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A BACILLUS DNA POLYMERASE I PRODUCT COMPLEX BOUND TO A GUANINE-THYMINE MISMATCH AFTER TWO ROUNDS OF PRIMER EXTENSION, FOLLOWING INCORPORATION OF DCTP AND DGTP.
Descriptor:DNA PRIMER STRAND, DNA TEMPLATE STRAND, DNA POLYMERASE I, ...
Authors:Johnson, S.J., Beese, L.S.
Deposit date:2003-01-02
Release date:2004-03-30
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structures of mismatch replication errors observed in a DNA polymerase.
Cell(Cambridge,Mass.), 116, 2004
1NKB
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A BACILLUS DNA POLYMERASE I PRODUCT COMPLEX BOUND TO A GUANINE-THYMINE MISMATCH AFTER THREE ROUNDS OF PRIMER EXTENSION, FOLLOWING INCORPORATION OF DCTP, DGTP, AND DTTP.
Descriptor:DNA PRIMER STRAND, DNA TEMPLATE STRAND, DNA POLYMERASE I, ...
Authors:Johnson, S.J., Beese, L.S.
Deposit date:2003-01-02
Release date:2004-03-30
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structures of mismatch replication errors observed in a DNA polymerase.
Cell(Cambridge,Mass.), 116, 2004
1NKC
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A BACILLUS DNA POLYMERASE I PRODUCT COMPLEX BOUND TO A GUANINE-THYMINE MISMATCH AFTER FIVE ROUNDS OF PRIMER EXTENSION, FOLLOWING INCORPORATION OF DCTP, DGTP, DTTP, AND DATP.
Descriptor:DNA PRIMER STRAND, DNA TEMPLATE STRAND, DNA POLYMERASE I, ...
Authors:Johnson, S.J., Beese, L.S.
Deposit date:2003-01-02
Release date:2004-03-30
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structures of mismatch replication errors observed in a DNA polymerase.
Cell(Cambridge,Mass.), 116, 2004
1NKE
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A BACILLUS DNA POLYMERASE I PRODUCT COMPLEX BOUND TO A CYTOSINE-THYMINE MISMATCH AFTER A SINGLE ROUND OF PRIMER EXTENSION, FOLLOWING INCORPORATION OF DCTP.
Descriptor:DNA PRIMER STRAND, DNA TEMPLATE STRAND, DNA POLYMERASE I, ...
Authors:Johnson, S.J., Beese, L.S.
Deposit date:2003-01-02
Release date:2004-03-30
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structures of mismatch replication errors observed in a DNA polymerase.
Cell(Cambridge,Mass.), 116, 2004
1U45
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8OXOGUANINE AT THE PRE-INSERTION SITE OF THE POLYMERASE ACTIVE SITE
Descriptor:DNA primer strand, DNA template strand with 8-oxoguanine, DNA polymerase I, ...
Authors:Hsu, G.W., Ober, M., Carell, T., Beese, L.S.
Deposit date:2004-07-23
Release date:2004-09-14
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.01 Å)
Cite:Error-prone replication of oxidatively damaged DNA by a high-fidelity DNA polymerase.
Nature, 431, 2004
1U47
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CYTOSINE-8-OXOGUANINE BASE PAIR AT THE POLYMERASE ACTIVE SITE
Descriptor:DNA primer strand, DNA template strand with 8-oxoguanine, DNA polymerase I, ...
Authors:Hsu, G.W., Ober, M., Carell, T., Beese, L.S.
Deposit date:2004-07-23
Release date:2004-09-14
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Error-prone replication of oxidatively damaged DNA by a high-fidelity DNA polymerase.
Nature, 431, 2004
1U48
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EXTENSION OF A CYTOSINE-8-OXOGUANINE BASE PAIR
Descriptor:DNA primer strand, DNA template strand with 8-oxoguanine, DNA polymerase I, ...
Authors:Hsu, G.W., Ober, M., Carell, T., Beese, L.S.
Deposit date:2004-07-23
Release date:2004-09-14
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Error-prone replication of oxidatively damaged DNA by a high-fidelity DNA polymerase.
Nature, 431, 2004
1U49
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ADENINE-8OXOGUANINE MISMATCH AT THE POLYMERASE ACTIVE SITE
Descriptor:DNA primer strand, DNA template strand with 8-oxoguanine, DNA polymerase I, ...
Authors:Hsu, G.W., Ober, M., Carell, T., Beese, L.S.
Deposit date:2004-07-23
Release date:2004-09-14
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:Error-prone replication of oxidatively damaged DNA by a high-fidelity DNA polymerase.
Nature, 431, 2004
1U4B
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EXTENSION OF AN ADENINE-8OXOGUANINE MISMATCH
Descriptor:DNA primer strand, DNA template strand with 8-oxoguanine, DNA polymerase I, ...
Authors:Hsu, G.W., Ober, M., Carell, T., Beese, L.S.
Deposit date:2004-07-23
Release date:2004-09-14
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Error-prone replication of oxidatively damaged DNA by a high-fidelity DNA polymerase.
Nature, 431, 2004