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Crystal Structure of the Rat Androgen Receptor Ligand Binding Domain Complex with BMS-564929
Descriptor:	2-CHLORO-4-[(7R,7AS)-7-HYDROXY-1,3-DIOXOTETRAHYDRO-1H-PYRROLO[1,2-C]IMIDAZOL-2(3H)-YL]-3-METHYLBENZONITRILE, Androgen receptor
Authors:	Ostrowski, J, Kuhns, J.E, Lupisella, J.A, Manfredi, M.C, Beehler, B.C, Krystek, S.R, Bi, Y, Sun, C, Seethala, R, Golla, R, Sleph, P.G, Fura, A, An, Y, Kish, K.F, Sack, J.S, Mookhtiar, K.A, Grover, G.J, Hamann, L.G.
Deposit date:	2006-11-14
Release date:	2006-12-12
Last modified:	2023-08-30
Method:	X-RAY DIFFRACTION (3 Å)
Cite:	Pharmacological and x-ray structural characterization of a novel selective androgen receptor modulator: potent hyperanabolic stimulation of skeletal muscle with hypostimulation of prostate in rats. Endocrinology, 148, 2007

Crystal Structure of the Rat Androgen Receptor Ligand Binding Domian Complex with an N-Aryl-Hydroxybicyclohydantoin
Descriptor:	4-[(7R,7AS)-7-HYDROXY-1,3-DIOXOTETRAHYDRO-1H-PYRROLO[1,2-C]IMIDAZOL-2(3H)-YL]-1-NAPHTHONITRILE, Androgen receptor
Authors:	Sack, J.S.
Deposit date:	2006-09-27
Release date:	2006-12-12
Last modified:	2023-08-30
Method:	X-RAY DIFFRACTION (2 Å)
Cite:	Discovery of potent, orally-active, and muscle-selective androgen receptor modulators based on an N-aryl-hydroxybicyclohydantoin scaffold. J.Med.Chem., 49, 2006

Crystal structure of the rat androgen receptor ligand binding domain complex with an n-aryl-oxazolidin 2-imine inhibitor
Descriptor:	2-chloro-4-{[(1R,3Z,7S,7aS)-7-hydroxy-1-(trifluoromethyl)tetrahydro-1H-pyrrolo[1,2-c][1,3]oxazol-3-ylidene]amino}-3-met hylbenzonitrile, Androgen receptor
Authors:	Sack, J.S.
Deposit date:	2009-01-29
Release date:	2009-04-28
Last modified:	2024-02-21
Method:	X-RAY DIFFRACTION (1.95 Å)
Cite:	N-aryl-oxazolidin-2-imine muscle selective androgen receptor modulators enhance potency through pharmacophore reorientation. J.Med.Chem., 52, 2009