Author results

2LDA
  • Download 2lda
  • View 2lda
Molmil generated image of 2lda
SOLUTION STRUCTURE OF THE ESTROGEN RECEPTOR-BINDING STAPLED PEPTIDE SP2 (AC-HKXLHQXLQDS-NH2)
Descriptor:Estrogen receptor-binding stapled peptide SP2
Authors:Phillips, C., Bazin, R., Bent, A., Davies, N., Moore, R., Pannifer, A., Pickford, A., Prior, S., Read, C., Roberts, L., Schade, M., Scott, A., Brown, D., Xu, B., Irving, S.
Deposit date:2011-05-20
Release date:2011-07-06
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Design and structure of stapled peptides binding to estrogen receptors.
J.Am.Chem.Soc., 133, 2011
2LDC
  • Download 2ldc
  • View 2ldc
Molmil generated image of 2ldc
SOLUTION STRUCTURE OF THE ESTROGEN RECEPTOR-BINDING STAPLED PEPTIDE SP1 (AC-HXILHXLLQDS-NH2)
Descriptor:Estrogen receptor-binding stapled peptide SP1
Authors:Phillips, C., Bazin, R., Bent, A., Davies, N., Moore, R., Pannifer, A., Pickford, A., Prior, S., Read, C., Roberts, L., Schade, M., Scott, A., Brown, D., Xu, B., Irving, S.
Deposit date:2011-05-20
Release date:2011-07-06
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Design and structure of stapled peptides binding to estrogen receptors.
J.Am.Chem.Soc., 133, 2011
2LDD
  • Download 2ldd
  • View 2ldd
Molmil generated image of 2ldd
SOLUTION STRUCTURE OF THE ESTROGEN RECEPTOR-BINDING STAPLED PEPTIDE SP6 (AC-EKHKILXRLLXDS-NH2)
Descriptor:Estrogen receptor-binding stapled peptide SP6
Authors:Phillips, C., Bazin, R., Bent, A., Davies, N., Moore, R., Pannifer, A., Pickford, A., Prior, S., Read, C., Roberts, L., Schade, M., Scott, A., Brown, D., Xu, B., Irving, S.
Deposit date:2011-05-21
Release date:2011-07-06
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Design and structure of stapled peptides binding to estrogen receptors.
J.Am.Chem.Soc., 133, 2011
2YJA
  • Download 2yja
  • View 2yja
Molmil generated image of 2yja
STAPLED PEPTIDES BINDING TO ESTROGEN RECEPTOR ALPHA.
Descriptor:STAPLED PEPTIDE, ESTROGEN RECEPTOR, ESTRADIOL
Authors:Phillips, C., Roberts, L.R., Schade, M., Bazin, R., Bent, A., Davies, N.L., Irving, S.L., Moore, R., Pannifer, A.D., Brown, D.G., Pickford, A.R., Scott, A., Xu, B.
Deposit date:2011-05-19
Release date:2011-08-03
Method:X-RAY DIFFRACTION (1.82 Å)
Cite:Design and Structure of Stapled Peptides Binding to Estrogen Receptors.
J.Am.Chem.Soc., 133, 2011
2XDE
  • Download 2xde
  • View 2xde
Molmil generated image of 2xde
CRYSTAL STRUCTURE OF THE COMPLEX OF PF-3450074 WITH AN ENGINEERED HIV CAPSID N TERMINAL DOMAIN
Descriptor:GAG POLYPROTEIN, N-METHYL-NALPHA-[(2-METHYL-1H-INDOL-3-YL)ACETYL]-N-PHENYL-L-PHENYLALANINAMIDE
Authors:Brown, D.G., Irving, S.L., Anderson, M., Bazin, R.
Deposit date:2010-04-30
Release date:2010-12-22
Last modified:2019-05-22
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:HIV Capsid is a Tractable Target for Small Molecule Therapeutic Intervention.
Plos Pathog., 6, 2010
2YJD
  • Download 2yjd
  • View 2yjd
Molmil generated image of 2yjd
STAPLED PEPTIDE BOUND TO ESTROGEN RECEPTOR BETA
Descriptor:ESTROGEN RECEPTOR BETA, STAPLED PEPTIDE, 4-(2-PROPAN-2-YLOXYBENZIMIDAZOL-1-YL)PHENOL
Authors:Phillips, C., Roberts, L.R., Schade, M., Bent, A., Davies, N.L., Moore, R., Pannifer, A.D., Brown, D.G., Pickford, A.R., Irving, S.L.
Deposit date:2011-05-19
Release date:2011-08-03
Last modified:2017-01-25
Method:X-RAY DIFFRACTION (1.93 Å)
Cite:Design and Structure of Stapled Peptides Binding to Estrogen Receptors.
J.Am.Chem.Soc., 133, 2011
5L8I
  • Download 5l8i
  • View 5l8i
Molmil generated image of 5l8i
CRYSTAL STRUCTURE OF HUMAN FABP6 APO-PROTEIN
Descriptor:Gastrotropin, TRIETHYLENE GLYCOL, 3,6,9,12,15,18-HEXAOXAICOSANE-1,20-DIOL, ...
Authors:Hendrick, A., Mueller, I., Leonard, P.M., Davenport, R., Mitchell, P.
Deposit date:2016-06-08
Release date:2016-08-24
Last modified:2016-09-21
Method:X-RAY DIFFRACTION (1.88 Å)
Cite:Identification and Investigation of Novel Binding Fragments in the Fatty Acid Binding Protein 6 (FABP6).
J.Med.Chem., 59, 2016
5L8N
  • Download 5l8n
  • View 5l8n
Molmil generated image of 5l8n
CRYSTAL STRUCTURE OF HUMAN FABP6 PROTEIN WITH FRAGMENT 1
Descriptor:Gastrotropin, 5,6-dimethyl-1~{H}-benzimidazol-2-amine, DI(HYDROXYETHYL)ETHER, ...
Authors:Hendrick, A., Mueller, I., Leonard, P.M., Davenport, R., Mitchell, P.
Deposit date:2016-06-08
Release date:2016-08-24
Last modified:2016-09-21
Method:X-RAY DIFFRACTION (2.12 Å)
Cite:Identification and Investigation of Novel Binding Fragments in the Fatty Acid Binding Protein 6 (FABP6).
J.Med.Chem., 59, 2016
5L8O
  • Download 5l8o
  • View 5l8o
Molmil generated image of 5l8o
CRYSTAL STRUCTURE OF HUMAN FABP6 IN COMPLEX WITH CHOLATE
Descriptor:Gastrotropin, DI(HYDROXYETHYL)ETHER, CHOLIC ACID
Authors:Hendrick, A., Mueller, I., Leonard, P.M., Davenport, R., Mitchell, P.
Deposit date:2016-06-08
Release date:2016-08-24
Last modified:2016-09-21
Method:X-RAY DIFFRACTION (2.39 Å)
Cite:Identification and Investigation of Novel Binding Fragments in the Fatty Acid Binding Protein 6 (FABP6).
J.Med.Chem., 59, 2016
2YIS
  • Download 2yis
  • View 2yis
Molmil generated image of 2yis
TRIAZOLOPYRIDINE INHIBITORS OF P38 KINASE.
Descriptor:MITOGEN-ACTIVATED PROTEIN KINASE 14, 1-[3-tert-butyl-1-(3-chloro-4-hydroxyphenyl)-1H-pyrazol-5-yl]-3-{2-[(3-{2-[(2-hydroxyethyl)sulfanyl]phenyl}[1,2,4]triazolo[4,3-a]pyridin-6-yl)sulfanyl]benzyl}urea, 2-fluoro-4-[4-(4-fluorophenyl)-1H-pyrazol-3-yl]pyridine
Authors:Millan, D.S., Anderson, M., Bazin, R., Bunnage, M.E., Burrows, J.L., Butcher, K.J., Dodd, P.G., Evans, T.J., Fairman, D.A., Hughes, S.J., Irving, S.L., Kilty, I.C., Lemaitre, A., Lewthwaite, R.A., Mahnke, A., Mathais, J.P., Philip, J., Phillips, C., Smith, R.T., Stefaniack, M.H., Yeadon, M.
Deposit date:2011-05-16
Release date:2011-11-30
Method:X-RAY DIFFRACTION (2 Å)
Cite:Design and Synthesis of Inhaled P38 Inhibitors for the Treatment of Chronic Obstructive Pulmonary Disease.
J.Med.Chem., 54, 2011
2YLY
  • Download 2yly
  • View 2yly
Molmil generated image of 2yly
SULFONAMIDES AS SELECTIVE ESTROGEN RECEPTOR BETA AGONISTS.
Descriptor:ESTROGEN RECEPTOR BETA, N-cyclopropyl-4-oxidanyl-N-[(2R)-2-oxidanyl-2-phenyl-propyl]benzenesulfonamide, SULFATE ION
Authors:Roberts, L.R., Armour, D., Barker, C., Bazin, R., Bess, K., Brown, A., Favor, D., Ellis, D., MacKenny, M., Pullen, N., Stennett, A., Strand, L., Styles, M., Phillips, C.
Deposit date:2011-06-06
Release date:2012-06-13
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Sulfonamides as Selective Oestrogen Receptor Beta Agonists.
Bioorg.Med.Chem.Lett., 21, 2011