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5AQ7
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DARPIN-BASED CRYSTALLIZATION CHAPERONES EXPLOIT MOLECULAR GEOMETRY AS A SCREENING DIMENSION IN PROTEIN CRYSTALLOGRAPHY
Descriptor:D12_DB04V3, MALONATE ION
Authors:Batyuk, A., Wu, Y., Honegger, A., Heberling, M., Plueckthun, A.
Deposit date:2015-09-21
Release date:2016-03-23
Last modified:2016-05-25
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Darpin-Based Crystallization Chaperones Exploit Molecular Geometry as a Screening Dimension in Protein Crystallography
J.Mol.Biol., 428, 2016
5AQ8
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DARPIN-BASED CRYSTALLIZATION CHAPERONES EXPLOIT MOLECULAR GEOMETRY AS A SCREENING DIMENSION IN PROTEIN CRYSTALLOGRAPHY
Descriptor:OFF7_DB12V4, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, THIOCYANATE ION
Authors:Batyuk, A., Wu, Y., Honegger, A., Heberling, M., Plueckthun, A.
Deposit date:2015-09-21
Release date:2016-03-23
Last modified:2016-05-18
Method:X-RAY DIFFRACTION (1.62 Å)
Cite:Darpin-Based Crystallization Chaperones Exploit Molecular Geometry as a Screening Dimension in Protein Crystallography
J.Mol.Biol., 428, 2016
5AQ9
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DARPIN-BASED CRYSTALLIZATION CHAPERONES EXPLOIT MOLECULAR GEOMETRY AS A SCREENING DIMENSION IN PROTEIN CRYSTALLOGRAPHY
Descriptor:OFF7_DB08V4, MALTOSE-BINDING PERIPLASMIC PROTEIN
Authors:Batyuk, A., Wu, Y., Honegger, A., Heberling, M., Plueckthun, A.
Deposit date:2015-09-21
Release date:2016-03-23
Last modified:2016-05-18
Method:X-RAY DIFFRACTION (1.86 Å)
Cite:Darpin-Based Crystallization Chaperones Exploit Molecular Geometry as a Screening Dimension in Protein Crystallography
J.Mol.Biol., 428, 2016
5AQA
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DARPIN-BASED CRYSTALLIZATION CHAPERONES EXPLOIT MOLECULAR GEOMETRY AS A SCREENING DIMENSION IN PROTEIN CRYSTALLOGRAPHY
Descriptor:OFF7_DB04V3, THIOCYANATE ION
Authors:Batyuk, A., Wu, Y., Honegger, A., Heberling, M., Plueckthun, A.
Deposit date:2015-09-21
Release date:2016-03-23
Last modified:2016-05-18
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Darpin-Based Crystallization Chaperones Exploit Molecular Geometry as a Screening Dimension in Protein Crystallography
J.Mol.Biol., 428, 2016
5AQB
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DARPIN-BASED CRYSTALLIZATION CHAPERONES EXPLOIT MOLECULAR GEOMETRY AS A SCREENING DIMENSION IN PROTEIN CRYSTALLOGRAPHY
Descriptor:3G61_DB15V4, GREEN FLUORESCENT PROTEIN
Authors:Batyuk, A., Wu, Y., Honegger, A., Heberling, M., Plueckthun, A.
Deposit date:2015-09-21
Release date:2016-03-23
Last modified:2016-05-18
Method:X-RAY DIFFRACTION (1.37 Å)
Cite:Darpin-Based Crystallization Chaperones Exploit Molecular Geometry as a Screening Dimension in Protein Crystallography
J.Mol.Biol., 428, 2016
5FIN
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DARPINS AS A NEW TOOL FOR EXPERIMENTAL PHASING IN PROTEIN CRYSTALLOGRAPHY
Descriptor:NI3C DARPIN MUTANT5 HG-SITE N1, MERCURY (II) ION
Authors:Batyuk, A., Honegger, A., Andres, F., Briand, C., Gruetter, M., Plueckthun, A.
Deposit date:2015-09-30
Release date:2016-11-16
Last modified:2017-07-05
Method:X-RAY DIFFRACTION (2.34 Å)
Cite:Darpins as a New Tool for Experimental Phasing in Protein Crystallography
To be Published
5FIO
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DARPINS AS A NEW TOOL FOR EXPERIMENTAL PHASING IN PROTEIN CRYSTALLOGRAPHY
Descriptor:NI3C DARPIN MUTANT5 HG-SITE N1, MALTOSE-BINDING PERIPLASMIC PROTEIN, MERCURY (II) ION
Authors:Batyuk, A., Honegger, A., Andres, F., Briand, C., Gruetter, M., Plueckthun, A.
Deposit date:2015-09-30
Release date:2016-11-16
Last modified:2016-11-30
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Darpins as a New Tool for Experimental Phasing in Protein Crystallography
To be Published
5K2A
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2.5 ANGSTROM A2A ADENOSINE RECEPTOR STRUCTURE WITH SULFUR SAD PHASING USING XFEL DATA
Descriptor:Adenosine receptor A2a/Soluble cytochrome b562 chimera, 4-{2-[(7-amino-2-furan-2-yl[1,2,4]triazolo[1,5-a][1,3,5]triazin-5-yl)amino]ethyl}phenol, SODIUM ION, ...
Authors:Batyuk, A., Galli, L., Ishchenko, A., Han, G.W., Gati, C., Popov, P., Lee, M.-Y., Stauch, B., White, T.A., Barty, A., Aquila, A., Hunter, M.S., Liang, M., Boutet, S., Pu, M., Liu, Z.-J., Nelson, G., James, D., Li, C., Zhao, Y., Spence, J.C.H., Liu, W., Fromme, P., Katritch, V., Weierstall, U., Stevens, R.C., Cherezov, V., GPCR Network (GPCR)
Deposit date:2016-05-18
Release date:2016-09-21
Last modified:2018-11-28
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Native phasing of x-ray free-electron laser data for a G protein-coupled receptor.
Sci Adv, 2, 2016
5K2B
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2.5 ANGSTROM A2A ADENOSINE RECEPTOR STRUCTURE WITH MR PHASING USING XFEL DATA
Descriptor:Adenosine receptor A2a/Soluble cytochrome b562 chimera, 4-{2-[(7-amino-2-furan-2-yl[1,2,4]triazolo[1,5-a][1,3,5]triazin-5-yl)amino]ethyl}phenol, SODIUM ION, ...
Authors:Batyuk, A., Galli, L., Ishchenko, A., Han, G.W., Gati, C., Popov, P., Lee, M.-Y., Stauch, B., White, T.A., Barty, A., Aquila, A., Hunter, M.S., Liang, M., Boutet, S., Pu, M., Liu, Z.-J., Nelson, G., James, D., Li, C., Zhao, Y., Spence, J.C.H., Liu, W., Fromme, P., Katritch, V., Weierstall, U., Stevens, R.C., Cherezov, V., GPCR Network (GPCR)
Deposit date:2016-05-18
Release date:2016-09-21
Last modified:2018-11-28
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Native phasing of x-ray free-electron laser data for a G protein-coupled receptor.
Sci Adv, 2, 2016
5K2C
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1.9 ANGSTROM A2A ADENOSINE RECEPTOR STRUCTURE WITH SULFUR SAD PHASING AND PHASE EXTENSION USING XFEL DATA
Descriptor:Adenosine receptor A2a/Soluble cytochrome b562 chimera, 4-{2-[(7-amino-2-furan-2-yl[1,2,4]triazolo[1,5-a][1,3,5]triazin-5-yl)amino]ethyl}phenol, SODIUM ION, ...
Authors:Batyuk, A., Galli, L., Ishchenko, A., Han, G.W., Gati, C., Popov, P., Lee, M.-Y., Stauch, B., White, T.A., Barty, A., Aquila, A., Hunter, M.S., Liang, M., Boutet, S., Pu, M., Liu, Z.-J., Nelson, G., James, D., Li, C., Zhao, Y., Spence, J.C.H., Liu, W., Fromme, P., Katritch, V., Weierstall, U., Stevens, R.C., Cherezov, V., GPCR Network (GPCR)
Deposit date:2016-05-18
Release date:2016-09-21
Last modified:2018-11-28
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Native phasing of x-ray free-electron laser data for a G protein-coupled receptor.
Sci Adv, 2, 2016
5K2D
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1.9A ANGSTROM A2A ADENOSINE RECEPTOR STRUCTURE WITH MR PHASING USING XFEL DATA
Descriptor:Adenosine receptor A2a/Soluble cytochrome b562 chimera, 4-{2-[(7-amino-2-furan-2-yl[1,2,4]triazolo[1,5-a][1,3,5]triazin-5-yl)amino]ethyl}phenol, SODIUM ION, ...
Authors:Batyuk, A., Galli, L., Ishchenko, A., Han, G.W., Gati, C., Popov, P., Lee, M.-Y., Stauch, B., White, T.A., Barty, A., Aquila, A., Hunter, M.S., Liang, M., Boutet, S., Pu, M., Liu, Z.-J., Nelson, G., James, D., Li, C., Zhao, Y., Spence, J.C.H., Liu, W., Fromme, P., Katritch, V., Weierstall, U., Stevens, R.C., Cherezov, V., GPCR Network (GPCR)
Deposit date:2016-05-18
Release date:2016-09-21
Last modified:2018-11-28
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Native phasing of x-ray free-electron laser data for a G protein-coupled receptor.
Sci Adv, 2, 2016
5AAO
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CRYSTAL STRUCTURE OF FLUOROGEN-ACTIVATING DESIGNED ANKYRIN REPEAT PROTEIN (DARPIN) DIMER IN COMPLEX WITH MALACHITE GREEN
Descriptor:FAD3210, 4-[[4-(dimethylamino)cyclohexa-2,5-dien-1-ylidene]-(4-methoxyphenyl)methyl]-N,N-dimethyl-aniline
Authors:Batyuk, A., Schuetz, M., Kummer, L., Wu, Y., Mittl, P., Plueckthun, A.
Deposit date:2015-07-27
Release date:2016-02-03
Last modified:2017-03-22
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Generation of Fluorogen-Activating Designed Ankyrin Repeat Proteins (FADAs) as Versatile Sensor Tools.
J. Mol. Biol., 428, 2016
5LE2
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CRYSTAL STRUCTURE OF DARPIN-DARPIN RIGID FUSION, VARIANT DDD_D12_15_D12_15_D12
Descriptor:DDD_D12_15_D12_15_D12, THIOCYANATE ION, ACETATE ION
Authors:Batyuk, A., Wu, Y., Mittl, P.R., Plueckthun, A.
Deposit date:2016-06-29
Release date:2017-08-02
Last modified:2019-03-20
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Rigidly connected multispecific artificial binders with adjustable geometries.
Sci Rep, 7, 2017
5LE3
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CRYSTAL STRUCTURE OF DARPIN-DARPIN RIGID FUSION, VARIANT DD_D12_09_D12
Descriptor:DD_D12_09_D12
Authors:Batyuk, A., Wu, Y., Mittl, P.R., Plueckthun, A.
Deposit date:2016-06-29
Release date:2017-08-02
Last modified:2019-03-20
Method:X-RAY DIFFRACTION (3.5 Å)
Cite:Rigidly connected multispecific artificial binders with adjustable geometries.
Sci Rep, 7, 2017
5LE4
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CRYSTAL STRUCTURE OF DARPIN-DARPIN RIGID FUSION, VARIANT DD_D12_11_D12
Descriptor:DD_D12_11_D12
Authors:Batyuk, A., Wu, Y., Mittl, P.R., Plueckthun, A.
Deposit date:2016-06-29
Release date:2017-08-02
Last modified:2019-03-20
Method:X-RAY DIFFRACTION (2.35 Å)
Cite:Rigidly connected multispecific artificial binders with adjustable geometries.
Sci Rep, 7, 2017
5LE6
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CRYSTAL STRUCTURE OF DARPIN-DARPIN RIGID FUSION, VARIANT DD_D12_09_D12
Descriptor:DD_D12_09_D12, GLYCEROL, SULFATE ION
Authors:Batyuk, A., Wu, Y., Mittl, P.R., Plueckthun, A.
Deposit date:2016-06-29
Release date:2017-08-02
Last modified:2019-03-20
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Rigidly connected multispecific artificial binders with adjustable geometries.
Sci Rep, 7, 2017
5LE7
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CRYSTAL STRUCTURE OF DARPIN-DARPIN RIGID FUSION, VARIANT DD_D12_13_D12
Descriptor:DD_D12_13_D12, SULFATE ION
Authors:Batyuk, A., Wu, Y., Mittl, P.R., Plueckthun, A.
Deposit date:2016-06-29
Release date:2017-08-02
Last modified:2019-03-20
Method:X-RAY DIFFRACTION (2.104 Å)
Cite:Rigidly connected multispecific artificial binders with adjustable geometries.
Sci Rep, 7, 2017
5LE8
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CRYSTAL STRUCTURE OF DARPIN-DARPIN RIGID FUSION, VARIANT DD_D12_15_D12
Descriptor:DD_D12_15_D12, SULFATE ION, GLYCEROL, ...
Authors:Batyuk, A., Wu, Y., Mittl, P.R., Plueckthun, A.
Deposit date:2016-06-29
Release date:2017-08-02
Last modified:2019-03-20
Method:X-RAY DIFFRACTION (1.78 Å)
Cite:Rigidly connected multispecific artificial binders with adjustable geometries.
Sci Rep, 7, 2017
5LE9
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CRYSTAL STRUCTURE OF DARPIN-DARPIN RIGID FUSION, VARIANT DD_OFF7_09_3G124
Descriptor:DD_Off7_09_3G124, ACETATE ION
Authors:Batyuk, A., Wu, Y., Mittl, P.R., Plueckthun, A.
Deposit date:2016-06-29
Release date:2017-08-02
Last modified:2019-03-20
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Rigidly connected multispecific artificial binders with adjustable geometries.
Sci Rep, 7, 2017
5LEA
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CRYSTAL STRUCTURE OF DARPIN-DARPIN RIGID FUSION, VARIANT DD_OFF7_12_3G124
Descriptor:DD_Off7_12_3G124, (4S)-2-METHYL-2,4-PENTANEDIOL
Authors:Batyuk, A., Wu, Y., Mittl, P.R., Plueckthun, A.
Deposit date:2016-06-29
Release date:2017-08-02
Last modified:2019-03-20
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Rigidly connected multispecific artificial binders with adjustable geometries.
Sci Rep, 7, 2017
5LEB
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CRYSTAL STRUCTURE OF DARPIN-DARPIN RIGID FUSION, VARIANT DDD_D12_06_D12_06_D12
Descriptor:DDD_D12_06_D12_06_D12
Authors:Batyuk, A., Wu, Y., Mittl, P.R., Plueckthun, A.
Deposit date:2016-06-29
Release date:2017-08-02
Last modified:2019-03-20
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Rigidly connected multispecific artificial binders with adjustable geometries.
Sci Rep, 7, 2017
5LEC
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CRYSTAL STRUCTURE OF DARPIN-DARPIN RIGID FUSION, VARIANT DDD_D12_12_D12_12_D12
Descriptor:DDD_D12_12_D12_12_D12, 2-[3-(2-HYDROXY-1,1-DIHYDROXYMETHYL-ETHYLAMINO)-PROPYLAMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL
Authors:Batyuk, A., Wu, Y., Mittl, P.R., Plueckthun, A.
Deposit date:2016-06-29
Release date:2017-08-02
Last modified:2019-03-20
Method:X-RAY DIFFRACTION (2.506 Å)
Cite:Rigidly connected multispecific artificial binders with adjustable geometries.
Sci Rep, 7, 2017
5LED
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CRYSTAL STRUCTURE OF DARPIN-DARPIN RIGID FUSION, VARIANT DDD_D12_12_D12_12_D12
Descriptor:DDD_D12_12_D12_12_D12
Authors:Batyuk, A., Wu, Y., Mittl, P.R., Plueckthun, A.
Deposit date:2016-06-29
Release date:2017-08-02
Last modified:2019-03-20
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Rigidly connected multispecific artificial binders with adjustable geometries.
Sci Rep, 7, 2017
5LEE
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CRYSTAL STRUCTURE OF DARPIN-DARPIN RIGID FUSION, VARIANT DDD_D12_12_D12_12_D12
Descriptor:DDD_D12_12_D12_12_D12
Authors:Batyuk, A., Wu, Y., Mittl, P.R., Plueckthun, A.
Deposit date:2016-06-29
Release date:2017-08-02
Last modified:2019-03-20
Method:X-RAY DIFFRACTION (2.401 Å)
Cite:Rigidly connected multispecific artificial binders with adjustable geometries.
Sci Rep, 7, 2017
5LEL
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CRYSTAL STRUCTURE OF DARPIN-DARPIN RIGID FUSION, VARIANT DD_OFF7_10_3G124 IN COMPLEX WITH MALTOSE-BINDING PROTEIN AND GREEN FLUORESCENT PROTEIN
Descriptor:DD_Off7_10_3G124, Maltose-binding periplasmic protein, Green fluorescent protein
Authors:Batyuk, A., Wu, Y., Mittl, P.R., Plueckthun, A.
Deposit date:2016-06-30
Release date:2017-11-15
Last modified:2019-03-20
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Rigidly connected multispecific artificial binders with adjustable geometries.
Sci Rep, 7, 2017