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6XQD
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BU of 6xqd by Molmil
Crystal structure of the Thermus thermophilus 70S ribosome in complex with sarecycline, UUC-mRNA, and deacylated P-site tRNA at 2.80A resolution
Descriptor: 16S Ribosomal RNA, 23S Ribosomal RNA, 30S ribosomal protein S10, ...
Authors:Batool, Z, Lomakin, I.B, Bunick, C.G, Polikanov, Y.S.
Deposit date:2020-07-09
Release date:2020-08-05
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Sarecycline interferes with tRNA accommodation and tethers mRNA to the 70S ribosome.
Proc.Natl.Acad.Sci.USA, 117, 2020
6XQE
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BU of 6xqe by Molmil
Crystal structure of the Thermus thermophilus 70S ribosome in complex with sarecycline, UAA-mRNA, and deacylated P-site tRNA at 3.00A resolution
Descriptor: 16S Ribosomal RNA, 23S Ribosomal RNA, 30S ribosomal protein S10, ...
Authors:Batool, Z, Lomakin, I.B, Bunick, C.G, Polikanov, Y.S.
Deposit date:2020-07-09
Release date:2020-08-05
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (3 Å)
Cite:Sarecycline interferes with tRNA accommodation and tethers mRNA to the 70S ribosome.
Proc.Natl.Acad.Sci.USA, 117, 2020
6UO1
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BU of 6uo1 by Molmil
Crystal structure of the Thermus thermophilus 70S ribosome in complex with mRNA (containing pseudouridine at the first position of the codon) and deacylated A-, P-, and E-site tRNAs at 2.95A resolution
Descriptor: 16S Ribosomal RNA, 23S Ribosomal RNA, 30S ribosomal protein S10, ...
Authors:Batool, Z, Dobosz-Bartoszek, M, Polikanov, Y.S.
Deposit date:2019-10-14
Release date:2019-11-27
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (2.95 Å)
Cite:Pseudouridinylation of mRNA coding sequences alters translation.
Proc.Natl.Acad.Sci.USA, 116, 2019

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