Author results

5NFR
  • Download 5nfr
  • View 5nfr
Molmil generated image of 5nfr
CRYSTAL STRUCTURE OF MALATE DEHYDROGENASE FROM PLASMODIUM FALCIPARUM (PFMDH)
分子名称:Malate dehydrogenase, CITRIC ACID
著者Lunev, S., Romero, A.R., Batista, F.A., Wrenger, C., Groves, M.R.
登録日2017-03-15
公開日2018-01-31
最終更新日2018-10-24
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Oligomeric interfaces as a tool in drug discovery: Specific interference with activity of malate dehydrogenase of Plasmodium falciparum in vitro.
PLoS ONE, 13, 2018
6FBA
  • Download 6fba
  • View 6fba
Molmil generated image of 6fba
CRYSTAL STRUCTURE OF TRUNCATED ASPARTATE TRANSCARBAMOYLASE FROM PLASMODIUM FALCIPARUM WITH BOUND INHIBITOR 2,3-NAPHTHALENEDIOL
分子名称:Aspartate transcarbamoylase, SULFATE ION, naphthalene-2,3-diol, ...
著者Lunev, S., Bosch, S.S., Batista, F.A., Wang, C., Wrenger, C., Groves, M.R.
登録日2017-12-18
公開日2018-02-21
最終更新日2018-03-14
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Identification of a non-competitive inhibitor of Plasmodium falciparum aspartate transcarbamoylase.
Biochem. Biophys. Res. Commun., 497, 2018
3TKM
  • Download 3tkm
  • View 3tkm
Molmil generated image of 3tkm
CRYSTAL STRUCTURE PPAR DELTA BINDING GW0742
分子名称:Peroxisome proliferator-activated receptor delta, {4-[({2-[3-fluoro-4-(trifluoromethyl)phenyl]-4-methyl-1,3-thiazol-5-yl}methyl)sulfanyl]-2-methylphenoxy}acetic acid, GLYCEROL
著者Trivella, D.B.B., Batista, F.H., Polikarpov, I.
登録日2011-08-27
公開日2012-07-04
実験手法X-RAY DIFFRACTION (1.953 Å)
主引用文献Structural Insights into Human Peroxisome Proliferator Activated Receptor Delta (PPAR-Delta) Selective Ligand Binding.
Plos One, 7, 2012
6HL7
  • Download 6hl7
  • View 6hl7
Molmil generated image of 6hl7
CRYSTAL STRUCTURE OF TRUNCATED ASPARTATE TRANSCARBAMOYLASE FROM PLASMODIUM FALCIPARUM WITH MUTATED ACTIVE SITE (R109A/K138A) AND N-CARBAMOYL-L-PHOSPHATE BOUND
分子名称:Aspartate transcarbamoylase, PHOSPHORIC ACID MONO(FORMAMIDE)ESTER
著者Bosch, S.S., Lunev, S., Wrenger, C., Groves, M.R.
登録日2018-09-10
公開日2018-09-26
最終更新日2018-10-10
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Drug target validation of aspartate transcarbamoylase from Plasmodium falciparum
To Be Published
6AN1
  • Download 6an1
  • View 6an1
Molmil generated image of 6an1
CRYSTAL STRUCTURE OF THE COMPLEX BETWEEN PPARGAMMA LBD AND THE LIGAND AM-879
分子名称:Peroxisome proliferator-activated receptor gamma, 4-({2-[(1,3-dioxo-1,3-dihydro-2H-inden-2-ylidene)methyl]phenoxy}methyl)benzoic acid
著者Veras, H., Figueira, A.C., le Maire, A.
登録日2017-08-11
公開日2018-02-14
最終更新日2019-04-17
実験手法X-RAY DIFFRACTION (2.687 Å)
主引用文献Screening for PPAR Non-Agonist Ligands Followed by Characterization of a Hit, AM-879, with Additional No-Adipogenic and cdk5-Mediated Phosphorylation Inhibition Properties.
Front Endocrinol (Lausanne), 9, 2018