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3DFV
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BU of 3dfv by Molmil
Adjacent GATA DNA binding
Descriptor: DNA (5'-D(*DAP*DAP*DGP*DCP*DAP*DGP*DAP*DTP*DAP*DAP*DGP*DTP*DCP*DTP*DTP*DAP*DTP*DCP*DAP*DG)-3'), DNA (5'-D(*DTP*DTP*DCP*DTP*DGP*DAP*DTP*DAP*DAP*DGP*DAP*DCP*DTP*DTP*DAP*DTP*DCP*DTP*DGP*DC)-3'), Trans-acting T-cell-specific transcription factor GATA-3, ...
Authors:Bates, D.L, Kim, G.K, Guo, L, Chen, L.
Deposit date:2008-06-12
Release date:2008-07-29
Last modified:2017-10-25
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Crystal structures of multiple GATA zinc fingers bound to DNA reveal new insights into DNA recognition and self-association by GATA.
J.Mol.Biol., 381, 2008
3DFX
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BU of 3dfx by Molmil
Opposite GATA DNA binding
Descriptor: DNA (5'-D(*DAP*DAP*DGP*DGP*DTP*DTP*DAP*DTP*DCP*DTP*DCP*DTP*DGP*DAP*DTP*DTP*DTP*DAP*DTP*DC)-3'), DNA (5'-D(*DTP*DTP*DGP*DAP*DTP*DAP*DAP*DAP*DTP*DCP*DAP*DGP*DAP*DGP*DAP*DTP*DAP*DAP*DCP*DC)-3'), Trans-acting T-cell-specific transcription factor GATA-3, ...
Authors:Bates, D.L, Kim, G.K, Guo, L, Chen, L.
Deposit date:2008-06-12
Release date:2008-07-29
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Crystal structures of multiple GATA zinc fingers bound to DNA reveal new insights into DNA recognition and self-association by GATA.
J.Mol.Biol., 381, 2008
2O93
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BU of 2o93 by Molmil
Crystal structure of NFAT bound to the HIV-1 LTR tandem kappaB enhancer element
Descriptor: actor of activated T-cells, cytoplasmic 2, kappaB enhancer element, ...
Authors:Bates, D.L, Chen, L.
Deposit date:2006-12-13
Release date:2007-06-19
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (3.05 Å)
Cite:Crystal structure of NFAT bound to the HIV-1 LTR tandem kappaB enhancer element
Structure, 16, 2008
3QB7
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BU of 3qb7 by Molmil
Interleukin-4 mutant RGA bound to cytokine receptor common gamma
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Cytokine receptor common subunit gamma, ...
Authors:Bates, D.L, Junttila, I.S, Creusot, R.J, Moraga, I, Lupardus, P, Fathman, C.G, Paul, W.E, Garcia, K.C.
Deposit date:2011-01-12
Release date:2012-04-25
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (3.245 Å)
Cite:Redirecting cell-type specific cytokine responses with engineered interleukin-4 superkines.
Nat.Chem.Biol., 8, 2012
2A07
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BU of 2a07 by Molmil
Crystal Structure of Foxp2 bound Specifically to DNA.
Descriptor: 5'-D(*AP*AP*CP*TP*AP*TP*GP*AP*AP*AP*CP*AP*AP*AP*TP*TP*TP*TP*CP*CP*T)-3', 5'-D(*TP*TP*AP*GP*GP*AP*AP*AP*AP*TP*TP*TP*GP*TP*TP*TP*CP*AP*TP*AP*G)-3', Forkhead box protein P2, ...
Authors:Stroud, J.C, Wu, Y, Bates, D.L, Han, A, Nowick, K, Paabo, S, Tong, H, Chen, L.
Deposit date:2005-06-16
Release date:2006-01-31
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structure of the Forkhead Domain of FOXP2 Bound to DNA.
Structure, 14, 2006
2AS5
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BU of 2as5 by Molmil
Structure of the DNA binding domains of NFAT and FOXP2 bound specifically to DNA.
Descriptor: 5'-D(AP*AP*CP*TP*AP*TP*GP*AP*AP*AP*CP*AP*AP*AP*TP*TP*TP*TP*CP*CP*TP*)-3', 5'-D(TP*TP*AP*GP*GP*AP*AP*AP*AP*TP*TP*TP*GP*TP*TP*TP*CP*AP*TP*AP*GP*)-3', Forkhead box protein P2, ...
Authors:Wu, Y, Stroud, J.C, Borde, M, Bates, D.L, Guo, L, Han, A, Rao, A, Chen, L.
Deposit date:2005-08-22
Release date:2006-08-08
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:FOXP3 Controls Regulatory T Cell Function through Cooperation with NFAT.
Cell(Cambridge,Mass.), 126, 2006
3QB1
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BU of 3qb1 by Molmil
Interleukin-2 mutant D10
Descriptor: Interleukin-2
Authors:Levin, A.M, Bates, D.L, Ring, A.M, Lin, J.T, Su, L, Krieg, C, Bowman, G.R, Novick, P, Pande, V.S, Khort, H.E, Boyman, O, Fathman, C.G, Garcia, K.C.
Deposit date:2011-01-12
Release date:2012-04-11
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Exploiting a natural conformational switch to engineer an interleukin-2 'superkine'
Nature, 484, 2012
3QAZ
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BU of 3qaz by Molmil
IL-2 mutant D10 ternary complex
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Cytokine receptor common subunit gamma, Interleukin-2, ...
Authors:Levin, A.M, Bates, D.L, Ring, A.M, Lin, J.T, Su, L, Krieg, C, Bowman, G.R, Novick, P, Pande, V.S, Khort, H.E, Boyman, O, Gathman, C.G, Garcia, K.C.
Deposit date:2011-01-12
Release date:2012-04-11
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (3.802 Å)
Cite:Exploiting a natural conformational switch to engineer an interleukin-2 'superkine'
Nature, 484, 2012
4HCA
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BU of 4hca by Molmil
DNA binding by GATA transcription factor-complex 1
Descriptor: DNA (5'-D(*AP*AP*TP*GP*TP*CP*CP*AP*TP*CP*TP*GP*AP*TP*AP*AP*GP*AP*CP*G)-3'), DNA (5'-D(*TP*TP*CP*GP*TP*CP*TP*TP*AP*TP*CP*AP*GP*AP*TP*GP*GP*AP*CP*A)-3'), Trans-acting T-cell-specific transcription factor GATA-3, ...
Authors:Chen, Y, Bates, D.L, Dey, R, Chen, L.
Deposit date:2012-09-28
Release date:2012-12-05
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:DNA Binding by GATA Transcription Factor Suggests Mechanisms of DNA Looping and Long-Range Gene Regulation.
Cell Rep, 2, 2012
4HC7
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BU of 4hc7 by Molmil
Crystal structure of the full DNA binding domain of GATA3-complex 2
Descriptor: DNA (5'-D(*AP*AP*GP*GP*TP*TP*AP*TP*CP*TP*CP*TP*GP*AP*TP*TP*TP*AP*GP*G)-3'), DNA (5'-D(*TP*TP*CP*CP*TP*AP*AP*AP*TP*CP*AP*GP*AP*GP*AP*TP*AP*AP*CP*C)-3'), Trans-acting T-cell-specific transcription factor GATA-3, ...
Authors:Chen, Y, Bates, D.L, Dey, R, Chen, L.
Deposit date:2012-09-28
Release date:2012-12-05
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.65 Å)
Cite:DNA Binding by GATA Transcription Factor Suggests Mechanisms of DNA Looping and Long-Range Gene Regulation.
Cell Rep, 2, 2012
4HC9
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BU of 4hc9 by Molmil
DNA binding by GATA transcription factor-complex 3
Descriptor: DNA (5'-D(*AP*AP*GP*GP*TP*TP*AP*TP*CP*TP*CP*TP*GP*AP*TP*TP*TP*AP*GP*G)-3'), DNA (5'-D(*TP*TP*CP*CP*TP*AP*AP*AP*TP*CP*AP*GP*AP*GP*AP*TP*AP*AP*CP*C)-3'), Trans-acting T-cell-specific transcription factor GATA-3, ...
Authors:Chen, Y, Bates, D.L, Dey, R, Chen, L.
Deposit date:2012-09-28
Release date:2012-12-05
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:DNA Binding by GATA Transcription Factor Suggests Mechanisms of DNA Looping and Long-Range Gene Regulation.
Cell Rep, 2, 2012
2O94
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BU of 2o94 by Molmil
The 97H/F mutant Structure of a glutamine-rich domain from histone deacetylase 4
Descriptor: Histone deacetylase 4
Authors:Guo, L, Han, A, Bates, D.L, Chen, L.
Deposit date:2006-12-13
Release date:2007-02-27
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (3 Å)
Cite:Crystal structure of a conserved N-terminal domain of histone deacetylase 4 reveals functional insights into glutamine-rich domains.
Proc.Natl.Acad.Sci.Usa, 104, 2007
1P7H
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BU of 1p7h by Molmil
Structure of NFAT1 bound as a dimer to the HIV-1 LTR kB element
Descriptor: 5'-D(*AP*AP*TP*GP*GP*GP*GP*AP*CP*TP*TP*TP*CP*CP*A)-3', 5'-D(*TP*TP*TP*GP*GP*AP*AP*AP*GP*TP*CP*CP*CP*CP*A)-3', Nuclear factor of activated T-cells, ...
Authors:Giffin, M.J, Stroud, J.C, Bates, D.L, von Koenig, K.D, Hardin, J, Chen, L.
Deposit date:2003-05-01
Release date:2003-09-23
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structure of NFAT1 bound as a dimer to the HIV-1 LTR kappa B element
Nat.Struct.Biol., 10, 2003
2H8N
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BU of 2h8n by Molmil
Structure of a glutamine-rich domain from histone deacetylase 4
Descriptor: Histone deacetylase 4
Authors:Guo, L, Han, A, Bates, D.L, Chen, L.
Deposit date:2006-06-07
Release date:2007-02-27
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Crystal structure of a conserved N-terminal domain of histone deacetylase 4 reveals functional insights into glutamine-rich domains.
Proc.Natl.Acad.Sci.Usa, 104, 2007
3GUT
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BU of 3gut by Molmil
Crystal structure of a higher-order complex of p50:RelA bound to the HIV-1 LTR
Descriptor: HIV-LTR Core Forward Strand, HIV-LTR Core Reverse Strand, Nuclear factor NF-kappa-B p105 subunit, ...
Authors:Stroud, J.C, Oltman, A.J, Han, A, Bates, D.L, Chen, L.
Deposit date:2009-03-30
Release date:2009-09-08
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (3.59 Å)
Cite:Structural basis of HIV-1 activation by NF-kappaB--a higher-order complex of p50:RelA bound to the HIV-1 LTR.
J.Mol.Biol., 393, 2009
6O9I
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BU of 6o9i by Molmil
Ternary complex of mouse ECD with Fab1 and Fab2
Descriptor: 1,2-ETHANEDIOL, Fab 2 heavy chain, Fab1 heavy chain, ...
Authors:Min, X, Wang, Z.
Deposit date:2019-03-13
Release date:2020-01-22
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Molecular mechanism of an antagonistic antibody against glucose-dependent insulinotropic polypeptide receptor.
Mabs, 12, 2020
6O9H
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BU of 6o9h by Molmil
Mouse ECD with Fab1
Descriptor: Gastric inhibitory polypeptide receptor, Heavy chain, Light chain, ...
Authors:Min, X, Wang, Z.
Deposit date:2019-03-13
Release date:2020-01-22
Last modified:2020-04-01
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Molecular mechanism of an antagonistic antibody against glucose-dependent insulinotropic polypeptide receptor.
Mabs, 12, 2020
3FYL
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BU of 3fyl by Molmil
GR DNA binding domain:CGT complex
Descriptor: 1,2-ETHANEDIOL, DNA (5'-D(*AP*AP*GP*AP*AP*CP*AP*TP*TP*TP*TP*GP*TP*CP*CP*G)-3'), DNA (5'-D(*TP*CP*GP*GP*AP*CP*AP*AP*AP*AP*TP*GP*TP*TP*CP*T)-3'), ...
Authors:Pufall, M.A, Yamamoto, K.R, Meijsing, S.H.
Deposit date:2009-01-22
Release date:2009-04-21
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (1.63 Å)
Cite:DNA binding site sequence directs glucocorticoid receptor structure and activity.
Science, 324, 2009
3G6U
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BU of 3g6u by Molmil
GR DNA-binding domain:FKBP5 16bp complex-49
Descriptor: DNA (5'-D(*AP*AP*GP*AP*AP*CP*AP*CP*CP*CP*TP*GP*TP*TP*CP*T)-3'), DNA (5'-D(*TP*AP*GP*AP*AP*CP*AP*GP*GP*GP*TP*GP*TP*TP*CP*T)-3'), Glucocorticoid receptor, ...
Authors:Pufall, M.A, Yamamoto, K.R, Meijsing, S.H.
Deposit date:2009-02-08
Release date:2009-04-21
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:DNA binding site sequence directs glucocorticoid receptor structure and activity.
Science, 324, 2009
3G8U
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BU of 3g8u by Molmil
DNA binding domain:GilZ 16bp complex-5
Descriptor: DNA (5'-D(*AP*AP*GP*AP*AP*CP*AP*TP*TP*GP*GP*GP*TP*TP*CP*C)-3'), DNA (5'-D(*TP*GP*GP*AP*AP*CP*CP*CP*AP*AP*TP*GP*TP*TP*CP*T)-3'), Glucocorticoid receptor, ...
Authors:Pufall, M.A, Yamamoto, K.R, Meijsing, S.H.
Deposit date:2009-02-12
Release date:2009-04-21
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:DNA binding site sequence directs glucocorticoid receptor structure and activity.
Science, 324, 2009
3G6Q
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BU of 3g6q by Molmil
GR DNA binding domain:FKBP5 binding site complex-9
Descriptor: DNA (5'-D(*AP*AP*GP*AP*AP*CP*AP*CP*CP*CP*TP*GP*TP*TP*CP*T)-3'), DNA (5'-D(*TP*AP*GP*AP*AP*CP*AP*GP*GP*GP*TP*GP*TP*TP*CP*T)-3'), Glucocorticoid receptor, ...
Authors:Pufall, M.A, Yamamoto, K.R, Meijsing, S.H.
Deposit date:2009-02-08
Release date:2009-04-21
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.26 Å)
Cite:DNA binding site sequence directs glucocorticoid receptor structure and activity.
Science, 324, 2009
3G8X
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BU of 3g8x by Molmil
GR DNA binding domain:GilZ 16bp complex-65
Descriptor: 1,2-ETHANEDIOL, DNA (5'-D(*AP*AP*GP*AP*AP*CP*AP*TP*TP*GP*GP*GP*TP*TP*CP*C)-3'), DNA (5'-D(*TP*GP*GP*AP*AP*CP*CP*CP*AP*AP*TP*GP*TP*TP*CP*T)-3'), ...
Authors:Pufall, M.A, Yamamoto, K.R, Meijsing, S.H.
Deposit date:2009-02-12
Release date:2009-04-21
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:DNA binding site sequence directs glucocorticoid receptor structure and activity.
Science, 324, 2009
3G9J
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BU of 3g9j by Molmil
GR DNA binding domain:Pal, 18bp complex-36
Descriptor: 1,2-ETHANEDIOL, DNA (5'-D(*CP*CP*AP*GP*AP*AP*CP*AP*AP*AP*AP*TP*GP*TP*TP*CP*TP*G)-3'), DNA (5'-D(*CP*CP*AP*GP*AP*AP*CP*AP*TP*TP*TP*TP*GP*TP*TP*CP*TP*G)-3'), ...
Authors:Pufall, M.A, Yamamoto, K.R, Meijsing, S.H.
Deposit date:2009-02-13
Release date:2009-04-21
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.32 Å)
Cite:DNA binding site sequence directs glucocorticoid receptor structure and activity.
Science, 324, 2009
3G6P
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BU of 3g6p by Molmil
GR DNA binding domain:FKBP5 complex, 18bp
Descriptor: ACETATE ION, DNA (5'-D(*CP*CP*AP*GP*AP*AP*CP*AP*CP*CP*CP*TP*GP*TP*TP*CP*TP*G)-3'), DNA (5'-D(*CP*CP*AP*GP*AP*AP*CP*AP*GP*GP*GP*TP*GP*TP*TP*CP*TP*G)-3'), ...
Authors:Pufall, M.A, Yamamoto, K.R, Meijsing, S.H.
Deposit date:2009-02-07
Release date:2009-04-21
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (1.985 Å)
Cite:DNA binding site sequence directs glucocorticoid receptor structure and activity.
Science, 324, 2009
3G6T
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BU of 3g6t by Molmil
GR gamma DNA-binding domain:FKBP5 16bp complex-34
Descriptor: DNA (5'-D(*AP*AP*GP*AP*AP*CP*AP*GP*GP*GP*TP*GP*TP*TP*CP*T)-3'), DNA (5'-D(*TP*AP*GP*AP*AP*CP*AP*CP*CP*CP*TP*GP*TP*TP*CP*T)-3'), Glucocorticoid receptor, ...
Authors:Pufall, M.A, Yamamoto, K.R, Meijsing, S.H.
Deposit date:2009-02-08
Release date:2009-04-21
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:DNA binding site sequence directs glucocorticoid receptor structure and activity.
Science, 324, 2009

 

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