Author results

1IIM
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THYMIDYLYLTRANSFERASE COMPLEXED WITH TTP
Descriptor:glucose-1-phosphate thymidylyltransferase, THYMIDINE-5'-TRIPHOSPHATE
Authors:Barton, W.A., Lesniak, J., Biggins, J.B., Jeffrey, P.D., Jiang, J., Rajashankar, K.R., Thorson, J.S., Nikolov, D.B.
Deposit date:2001-04-23
Release date:2001-05-09
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structure, mechanism and engineering of a nucleotidylyltransferase as a first step toward glycorandomization.
Nat.Struct.Biol., 8, 2001
1IIN
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THYMIDYLYLTRANSFERASE COMPLEXED WITH UDP-GLUCOSE
Descriptor:glucose-1-phosphate thymidylyltransferase, URIDINE-5'-DIPHOSPHATE-GLUCOSE
Authors:Barton, W.A., Lesniak, J., Biggins, J.B., Jeffrey, P.D., Jiang, J., Rajashankar, K.R., Thorson, J.S., Nikolov, D.B.
Deposit date:2001-04-23
Release date:2001-05-09
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structure, mechanism and engineering of a nucleotidylyltransferase as a first step toward glycorandomization.
Nat.Struct.Biol., 8, 2001
1MP3
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L89T VARIANT OF S. ENTERICA RMLA
Descriptor:GLUCOSE-1-PHOSPHATE THYMIDYLYLTRANSFERASE, THYMIDINE-5'-TRIPHOSPHATE
Authors:Barton, W.A., Biggins, J.B., Jiang, J., Thorson, J.T., Nikolov, D.B.
Deposit date:2002-09-11
Release date:2002-10-09
Last modified:2018-01-31
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Expanding pyrimidine diphosphosugar libraries via structure-based nucleotidylyltransferase engineering
Proc.Natl.Acad.Sci.USA, 99, 2002
1MP4
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W224H VARIANT OF S. ENTERICA RMLA
Descriptor:W224H Variant of S. Enterica RmlA Bound to UDP-Glucose, URIDINE-5'-DIPHOSPHATE-GLUCOSE
Authors:Barton, W.A., Biggins, J.B., Jiang, J., Thorson, J.S., Nikolov, D.B.
Deposit date:2002-09-11
Release date:2002-10-09
Last modified:2018-01-31
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Expanding pyrimidine diphosphosugar libraries via structure-based nucleotidylyltransferase engineering
Proc.Natl.Acad.Sci.USA, 99, 2002
1MP5
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Y177F VARIANT OF S. ENTERICA RMLA
Descriptor:Y177F VARIANT OF S. ENTERICA RmlA BOUND TO UDP-GLUCOSE, URIDINE-5'-DIPHOSPHATE-GLUCOSE
Authors:Barton, W.A., Biggins, J.B., Jiang, J., Thorson, J.S., Nikolov, D.B.
Deposit date:2002-09-11
Release date:2002-10-09
Last modified:2018-01-31
Method:X-RAY DIFFRACTION (2.75 Å)
Cite:Expanding pyrimidine diphosphosugar libraries via structure-based nucleotidylyltransferase engineering
Proc.Natl.Acad.Sci.USA, 99, 2002
1P8T
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CRYSTAL STRUCTURE OF NOGO-66 RECEPTOR
Descriptor:Reticulon 4 receptor, N-ACETYL-D-GLUCOSAMINE, 2-(ACETYLAMINO)-2-DEOXY-A-D-GLUCOPYRANOSE
Authors:Barton, W.A., Liu, B.P., Tzvetkova, D., Jeffrey, P.D., Fournier, A.E., Sah, D., Cate, R., Strittmatter, S.M., Nikolov, D.B.
Deposit date:2003-05-07
Release date:2003-05-20
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Structure and axon outgrowth inhibitor binding of the Nogo-66 receptor and related proteins
Embo J., 22, 2003
1Z3S
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ANGIOPOIETIN-2 RECEPTOR BINDING DOMAIN
Descriptor:Angiopoietin-2, CALCIUM ION
Authors:Barton, W.A., Tzvetkova, D., Nikolov, D.B.
Deposit date:2005-03-14
Release date:2005-07-12
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.35 Å)
Cite:Structure of the angiopoietin-2 receptor binding domain and identification of surfaces involved in Tie2 recognition.
Structure, 13, 2005
1Z3U
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STRUCTURE OF THE ANGIOPOIETIN-2 RECPTOR BINDING DOMAIN AND IDENTIFICATION OF SURFACES INVOLVED IN TIE2 RECOGNITION
Descriptor:Angiopoietin-2, CALCIUM ION
Authors:Barton, W.A., Tzvetkova, D., Nikolov, D.B.
Deposit date:2005-03-14
Release date:2005-07-12
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:Structure of the angiopoietin-2 receptor binding domain and identification of surfaces involved in Tie2 recognition.
Structure, 13, 2005
2GY5
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TIE2 LIGAND-BINDING DOMAIN CRYSTAL STRUCTURE
Descriptor:Angiopoietin-1 receptor, N-ACETYL-D-GLUCOSAMINE, 2-(ACETYLAMINO)-2-DEOXY-A-D-GLUCOPYRANOSE, ...
Authors:Barton, W.A., Nikolov, D.B.
Deposit date:2006-05-09
Release date:2006-06-06
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Crystal structures of the Tie2 receptor ectodomain and the angiopoietin-2-Tie2 complex.
Nat.Struct.Mol.Biol., 13, 2006
2GY7
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ANGIOPOIETIN-2/TIE2 COMPLEX CRYSTAL STRUCTURE
Descriptor:Angiopoietin-2, Angiopoietin-1 receptor, CALCIUM ION, ...
Authors:Barton, W.A., Nikolov, D.B.
Deposit date:2006-05-09
Release date:2006-06-06
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3.7 Å)
Cite:Crystal structures of the Tie2 receptor ectodomain and the angiopoietin-2-Tie2 complex.
Nat.Struct.Mol.Biol., 13, 2006
1N2F
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CRYSTAL STRUCTURE OF P. AERUGINOSA OHR
Descriptor:Organic Hydroperoxide Resistance Protein, 2,3-DIHYDROXY-1,4-DITHIOBUTANE
Authors:Lesniak, J., Barton, W.A., Nikolov, D.B.
Deposit date:2002-10-22
Release date:2002-12-25
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.01 Å)
Cite:Structural and functional characterization of the Pseudomonas hydroperoxide resistance protein Ohr
Embo J., 21, 2002
1Q47
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STRUCTURE OF THE SEMAPHORIN 3A RECEPTOR-BINDING MODULE
Descriptor:Semaphorin 3A, N-ACETYL-D-GLUCOSAMINE
Authors:Antipenko, A., Himanen, J.-P., van Leyen, K., Nardi-Dei, V., Lesniak, J., Barton, W.A., Rajashankar, K.R., Lu, M., Hoemme, C., Puschel, A., Nikolov, D.
Deposit date:2003-08-01
Release date:2004-08-03
Last modified:2017-02-01
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structure of the semaphorin-3A receptor binding module.
Neuron, 39, 2003
1QWI
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CRYSTAL STRUCTURE OF E. COLI OSMC
Descriptor:osmotically inducible protein
Authors:Lesniak, J., Barton, W.A., Nikolov, D.B.
Deposit date:2003-09-02
Release date:2003-12-16
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structural and functional features of the Escherichia coli hydroperoxide resistance protein OsmC
Protein Sci., 12, 2003
1SHW
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EPHB2 / EPHRINA5 COMPLEX STRUCTURE
Descriptor:Ephrin-A5, Ephrin type-B receptor 2, N-ACETYL-D-GLUCOSAMINE, ...
Authors:Himanen, J.P., Chumley, M.J., Lackmann, M., Li, C., Barton, W.A., Jeffrey, P.D., Vearing, C., Geleick, D., Feldheim, D.A., Boyd, A.W.
Deposit date:2004-02-26
Release date:2004-05-18
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Repelling class discrimination: ephrin-A5 binds to and activates EphB2 receptor signaling
Nat.Neurosci., 7, 2004
2AO7
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ADAM10 DISINTEGRIN AND CYSTEINE- RICH DOMAIN
Descriptor:ADAM 10, SULFATE ION
Authors:Janes, P.W., Saha, N., Barton, W.A., Kolev, M.V., Wimmer-Kleikamp, S.H., Nievergall, E., Blobel, C.P., Himanen, J.-P., Lackmann, M., Nikolov, D.B.
Deposit date:2005-08-12
Release date:2006-08-08
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Adam meets Eph: an ADAM substrate recognition module acts as a molecular switch for ephrin cleavage in trans.
Cell(Cambridge,Mass.), 123, 2005
4JYO
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STRUCTURAL BASIS FOR ANGIOPOIETIN-1 MEDIATED SIGNALING INITIATION
Descriptor:Angiopoietin-1, CALCIUM ION
Authors:Yu, X., Seegar, T.C.M., Dalton, A.C., Tzvetkova-Robev, D., Goldgur, Y., Nikolov, D.B., Barton, W.A.
Deposit date:2013-03-31
Release date:2013-05-08
Last modified:2013-05-15
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structural basis for angiopoietin-1-mediated signaling initiation.
Proc.Natl.Acad.Sci.USA, 110, 2013
4JZC
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ANGIOPOIETIN-2 FIBRINOGEN DOMAIN TAG MUTANT
Descriptor:Angiopoietin-2
Authors:Yu, X., Seegar, T.C.M., Dalton, A.C., Tzvetkova-Robev, D., Goldgur, Y., Nikolov, D.B., Barton, W.A.
Deposit date:2013-04-02
Release date:2013-05-08
Last modified:2013-05-15
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structural basis for angiopoietin-1-mediated signaling initiation.
Proc.Natl.Acad.Sci.USA, 110, 2013
4K0V
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STRUCTURAL BASIS FOR ANGIOPOIETIN-1 MEDIATED SIGNALING INITIATION
Descriptor:TEK tyrosine kinase variant, Angiopoietin-1
Authors:Yu, X., Seegar, T.C.M., Dalton, A.C., Tzvetkova-Robev, D., Goldgur, Y., Nikolov, D.B., Barton, W.A.
Deposit date:2013-04-04
Release date:2013-05-08
Last modified:2013-05-15
Method:X-RAY DIFFRACTION (4.51 Å)
Cite:Structural basis for angiopoietin-1-mediated signaling initiation.
Proc.Natl.Acad.Sci.USA, 110, 2013
1SHX
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EPHRIN A5 LIGAND STRUCTURE
Descriptor:Ephrin-A5, N-ACETYL-D-GLUCOSAMINE
Authors:Himanen, J.P., Barton, W.A., Nikolov, D.B., Jeffrey, P.D.
Deposit date:2004-02-26
Release date:2005-04-19
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Three distinct molecular surfaces in ephrin-A5 are essential for a functional interaction with EphA3.
J.Biol.Chem., 280, 2005