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3EE7
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BU of 3ee7 by Molmil
Crystal Structure of SARS-CoV nsp9 G104E
Descriptor: GLYCEROL, PHOSPHATE ION, Replicase polyprotein 1a
Authors:Miknis, Z.J, Donaldson, E.F, Umland, T.C, Rimmer, R, Baric, R.S, Schultz, L.W.
Deposit date:2008-09-04
Release date:2009-03-24
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Severe acute respiratory syndrome coronavirus nsp9 dimerization is essential for efficient viral growth
J.Virol., 83, 2009
4L3N
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BU of 4l3n by Molmil
Crystal structure of the receptor-binding domain from newly emerged Middle East respiratory syndrome coronavirus
Descriptor: 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, S protein
Authors:Chen, Y, Rajashankar, K.R, Yang, Y, Agnihothram, S.S, Liu, C, Lin, Y.-L, Baric, R.S, Li, F.
Deposit date:2013-06-06
Release date:2013-07-31
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (2.13 Å)
Cite:Crystal structure of the receptor-binding domain from newly emerged middle East respiratory syndrome coronavirus.
J.Virol., 87, 2013
5H37
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BU of 5h37 by Molmil
Cryo-EM structure of zika virus complexed with Fab C10 at pH 8.0
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, C10 IgG heavy chain variable region, C10 IgG light chain variable region, ...
Authors:Zhang, S, Kostyuchenko, V, Ng, T.-S, Lim, X.-N, Ooi, J.S.G, Lambert, S, Tan, T.Y, Widman, D, Shi, J, Baric, R.S, Lok, S.-M.
Deposit date:2016-10-20
Release date:2016-11-30
Last modified:2022-03-23
Method:ELECTRON MICROSCOPY (4 Å)
Cite:Neutralization mechanism of a highly potent antibody against Zika virus
Nat Commun, 7, 2016
6XRZ
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BU of 6xrz by Molmil
The 28-kDa Frameshift Stimulation Element from the SARS-CoV-2 RNA Genome
Descriptor: Frameshift Stimulation Element from the SARS-CoV-2 RNA Genome
Authors:Zhang, K, Zheludev, I, Hagey, R, Wu, M, Haslecker, R, Hou, Y, Kretsch, R, Pintilie, G, Rangan, R, Kladwang, W, Li, S, Pham, E, Souibgui, C, Baric, R, Sheahan, T, Souza, V, Glenn, J, Chiu, W, Das, R.
Deposit date:2020-07-14
Release date:2020-08-19
Last modified:2024-03-06
Method:ELECTRON MICROSCOPY (6.9 Å)
Cite:Cryo-electron Microscopy and Exploratory Antisense Targeting of the 28-kDa Frameshift Stimulation Element from the SARS-CoV-2 RNA Genome.
Biorxiv, 2020
6N81
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BU of 6n81 by Molmil
Crystal structure of GII.4 2002 norovirus P domain in complex with cross-reactive human antibody A1227
Descriptor: A1227 Fab heavy chain, A1227 Fab light chain, Major capsid protein
Authors:Changela, A, Verardi, R, Kwong, P.D.
Deposit date:2018-11-28
Release date:2019-06-19
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.579 Å)
Cite:Sera Antibody Repertoire Analyses Reveal Mechanisms of Broad and Pandemic Strain Neutralizing Responses after Human Norovirus Vaccination.
Immunity, 50, 2019
8SAK
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BU of 8sak by Molmil
BtCoV-422 in complex with neutralizing antibody JC57-11
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:McFadden, E, McLellan, J.S.
Deposit date:2023-04-01
Release date:2023-10-04
Method:ELECTRON MICROSCOPY (3 Å)
Cite:A MERS-CoV antibody neutralizes a pre-emerging group 2c bat coronavirus.
Sci Transl Med, 15, 2023
6N8D
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BU of 6n8d by Molmil
Crystal structure of GII.4 2002 norovirus P domain in complex with neutralizing human antibody A1431
Descriptor: A1431 Fab heavy chain, A1431 Fab light chain, Major capsid protein
Authors:Changela, A, Verardi, R, Kwong, P.D.
Deposit date:2018-11-29
Release date:2019-06-19
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Sera Antibody Repertoire Analyses Reveal Mechanisms of Broad and Pandemic Strain Neutralizing Responses after Human Norovirus Vaccination.
Immunity, 50, 2019
7MLZ
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BU of 7mlz by Molmil
Cryo-EM structure of SARS-CoV-2 spike in complex with neutralizing antibody B1-182.1 that targets the receptor-binding domain
Descriptor: B1-182.1 Fab heavy chain, B1-182.1 Fab light chain, Spike protein S1, ...
Authors:Zhou, T, Tsybovsky, T, Kwong, P.D.
Deposit date:2021-04-29
Release date:2021-07-28
Last modified:2021-08-25
Method:ELECTRON MICROSCOPY (3.71 Å)
Cite:Ultrapotent antibodies against diverse and highly transmissible SARS-CoV-2 variants.
Science, 373, 2021
7MM0
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BU of 7mm0 by Molmil
Cryo-EM structure of SARS-CoV-2 spike in complex with neutralizing antibody B1-182.1 that targets the receptor-binding domain
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, B1-182.1 Fab heavy chain, ...
Authors:Zhou, T, Tsybovsky, T, Kwong, P.D.
Deposit date:2021-04-29
Release date:2021-07-28
Last modified:2021-08-25
Method:ELECTRON MICROSCOPY (3.15 Å)
Cite:Ultrapotent antibodies against diverse and highly transmissible SARS-CoV-2 variants.
Science, 373, 2021
7TB4
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BU of 7tb4 by Molmil
Cryo-EM structure of the spike of SARS-CoV-2 Omicron variant of concern
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Surface glycoprotein
Authors:Zhou, T, Tsybovsky, T, Kwong, P.D.
Deposit date:2021-12-21
Release date:2022-01-12
Last modified:2022-01-19
Method:ELECTRON MICROSCOPY (3.29 Å)
Cite:Antibodies with potent and broad neutralizing activity against antigenically diverse and highly transmissible SARS-CoV-2 variants.
Biorxiv, 2021
7T3M
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BU of 7t3m by Molmil
SARS-CoV-2 S (Spike Glycoprotein) D614G with Three (3) RBDs Up, Bound to Antibody 2-7 scFv, composite map
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Antibody 2-7 scFv, ...
Authors:Byrne, P.O, McLellan, J.S.
Deposit date:2021-12-08
Release date:2022-08-24
Last modified:2023-03-08
Method:ELECTRON MICROSCOPY (3 Å)
Cite:IgG-like bispecific antibodies with potent and synergistic neutralization against circulating SARS-CoV-2 variants of concern.
Nat Commun, 13, 2022
7T67
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BU of 7t67 by Molmil
SARS-CoV-2 S (Spike Glycoprotein) D614G with One(1) RBD Up
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein
Authors:Byrne, P.O, McLellan, J.S.
Deposit date:2021-12-13
Release date:2022-08-24
Last modified:2023-03-08
Method:ELECTRON MICROSCOPY (3 Å)
Cite:IgG-like bispecific antibodies with potent and synergistic neutralization against circulating SARS-CoV-2 variants of concern.
Nat Commun, 13, 2022
7S2R
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BU of 7s2r by Molmil
nanobody bound to IL-2Rg
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Cytokine receptor common subunit gamma, ...
Authors:Glassman, C.R, Jude, K.M, Yen, M, Garcia, K.C.
Deposit date:2021-09-03
Release date:2022-03-30
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.49 Å)
Cite:Facile discovery of surrogate cytokine agonists.
Cell, 185, 2022
7S2S
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BU of 7s2s by Molmil
nanobody bound to Interleukin-2Rbeta
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, IL2Rb-binding nanobody, Interleukin-2 receptor subunit beta, ...
Authors:Glassman, C.R, Jude, K.M, Yen, M, Garcia, K.C.
Deposit date:2021-09-03
Release date:2022-03-30
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.93 Å)
Cite:Facile discovery of surrogate cytokine agonists.
Cell, 185, 2022
7S3N
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BU of 7s3n by Molmil
SARS-CoV-2 S stem helix peptide bound to Fab22
Descriptor: Fab22 Heavy Chain, Fab22 Light Chain, Spike glycoprotein
Authors:Goldsmith, J.A, McLellan, J.S.
Deposit date:2021-09-07
Release date:2021-10-27
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Stabilized coronavirus spike stem elicits a broadly protective antibody.
Cell Rep, 37, 2021
7S3M
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BU of 7s3m by Molmil
MERS-CoV S stem helix peptide bound to Fab22
Descriptor: Fab22 Heavy Chain, Fab22 Light Chain, Spike glycoprotein
Authors:Goldsmith, J.A, McLellan, J.S.
Deposit date:2021-09-07
Release date:2021-10-27
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Stabilized coronavirus spike stem elicits a broadly protective antibody.
Cell Rep, 37, 2021
7SG4
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BU of 7sg4 by Molmil
Structure of SARS-CoV S protein in complex with Receptor Binding Domain antibody DH1047
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, DH1047 Heavy chain, DH1047 light chain, ...
Authors:Gobeil, S, Acharya, P.
Deposit date:2021-10-04
Release date:2021-11-10
Last modified:2022-02-09
Method:ELECTRON MICROSCOPY (3.43 Å)
Cite:A broadly cross-reactive antibody neutralizes and protects against sarbecovirus challenge in mice.
Sci Transl Med, 14, 2022
5H32
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BU of 5h32 by Molmil
Cryo-EM structure of zika virus complexed with Fab C10 at pH 5.0
Descriptor: C10 IgG heavy chain variable region, C10 IgG light chain variable region, structural protein E
Authors:Zhang, S, Kostyuchenko, V, Ng, T.-S, Lok, S.-M.
Deposit date:2016-10-20
Release date:2016-11-30
Last modified:2022-03-23
Method:ELECTRON MICROSCOPY (12 Å)
Cite:Neutralization mechanism of a highly potent antibody against Zika virus
Nat Commun, 7, 2016
5H30
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BU of 5h30 by Molmil
Cryo-EM structure of zika virus complexed with Fab C10 at pH 6.5
Descriptor: IgG C10 heavy chain, IgG C10 light chain, structural protein E, ...
Authors:Zhang, S, Kostyuchenko, V, Ng, T.-S, Lok, S.-M.
Deposit date:2016-10-19
Release date:2016-11-30
Last modified:2022-03-23
Method:ELECTRON MICROSCOPY (4.4 Å)
Cite:Neutralization mechanism of a highly potent antibody against Zika virus
Nat Commun, 7, 2016
8DI5
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BU of 8di5 by Molmil
Cryo-EM structure of SARS-CoV-2 Beta (B.1.351) spike protein in complex with VH domain F6 (focused refinement of RBD and VH F6)
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein, VH F6
Authors:Zhu, X, Saville, J.W, Mannar, D, Berezuk, A.M, Subramaniam, S.
Deposit date:2022-06-28
Release date:2022-08-24
Method:ELECTRON MICROSCOPY (3.04 Å)
Cite:Potent and broad neutralization of SARS-CoV-2 variants of concern (VOCs) including omicron sub-lineages BA.1 and BA.2 by biparatopic human VH domains.
Iscience, 25, 2022
8DGV
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BU of 8dgv by Molmil
Crystal structure of MERS-CoV spike stem helix peptide in complex with Fab of broadly neutralizing antibody CC99.103 isolated from a vaccinated COVID-19 convalescent
Descriptor: Antibody CC99.103 Fab heavy chain, Antibody CC99.103 Fab light chain, Spike protein S2'
Authors:Liu, H, Wilson, I.A.
Deposit date:2022-06-24
Release date:2023-01-25
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Broadly neutralizing anti-S2 antibodies protect against all three human betacoronaviruses that cause deadly disease.
Immunity, 56, 2023
8DGW
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BU of 8dgw by Molmil
Crystal structure of HCoV-HKU1 spike stem helix peptide in complex with Fab of broadly neutralizing antibody CC95.108 isolated from a vaccinated COVID-19 convalescent
Descriptor: Antibody CC95.108 Fab heavy chain, Antibody CC95.108 Fab light chain, Spike protein S2'
Authors:Liu, H, Wilson, I.A.
Deposit date:2022-06-24
Release date:2023-01-25
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2.81 Å)
Cite:Broadly neutralizing anti-S2 antibodies protect against all three human betacoronaviruses that cause deadly disease.
Immunity, 56, 2023
8DGU
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BU of 8dgu by Molmil
Crystal structure of SARS-CoV-2 spike stem helix peptide in complex with Fab of broadly neutralizing antibody CC25.106 isolated from a vaccinated COVID-19 convalescent
Descriptor: Antibody CC25.106 Fab heavy chain, Antibody CC25.106 Fab light chain, GLYCEROL, ...
Authors:Liu, H, Wilson, I.A.
Deposit date:2022-06-24
Release date:2023-01-25
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (1.89 Å)
Cite:Broadly neutralizing anti-S2 antibodies protect against all three human betacoronaviruses that cause deadly disease.
Immunity, 56, 2023
8DGX
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BU of 8dgx by Molmil
Crystal structure of MERS-CoV spike stem helix peptide in complex with Fab of broadly neutralizing antibody CC68.109 isolated from a vaccinated COVID-19 convalescent
Descriptor: Antibody CC68.109 Fab heavy chain, Antibody CC68.109 Fab light chain, Spike protein S2'
Authors:Liu, H, Wilson, I.A.
Deposit date:2022-06-24
Release date:2023-01-25
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2.89 Å)
Cite:Broadly neutralizing anti-S2 antibodies protect against all three human betacoronaviruses that cause deadly disease.
Immunity, 56, 2023
8DTK
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BU of 8dtk by Molmil
Structure of RBD directed antibody DH1047 in complex with SARS-CoV-2 spike: Local refinement of RBD-Fab interace
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, DH1047 Fab Heavy Chain, DH1047 Fab Light Chain, ...
Authors:May, A.J, Manne, K, Acharya, P.
Deposit date:2022-07-25
Release date:2023-08-02
Last modified:2024-02-28
Method:ELECTRON MICROSCOPY (3.77 Å)
Cite:Broadly neutralizing antibody induction by non-stabilized SARS-CoV-2 Spike mRNA vaccination in nonhuman primates.
Biorxiv, 2023

 

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