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1GPA
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STRUCTURAL MECHANISM FOR GLYCOGEN PHOSPHORYLASE CONTROL BY PHOSPHORYLATION AND AMP
分子名称:GLYCOGEN PHOSPHORYLASE A, SULFATE ION, PYRIDOXAL-5'-PHOSPHATE
著者Barford, D., Hu, S.-H., Johnson, L.N.
登録日1990-11-13
公開日1992-10-15
最終更新日2017-11-29
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Structural mechanism for glycogen phosphorylase control by phosphorylation and AMP.
J.Mol.Biol., 218, 1991
7GPB
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STRUCTURAL MECHANISM FOR GLYCOGEN PHOSPHORYLASE CONTROL BY PHOSPHORYLATION AND AMP
分子名称:GLYCOGEN PHOSPHORYLASE B, SULFATE ION, PYRIDOXAL-5'-PHOSPHATE, ...
著者Barford, D., Hu, S.-H., Johnson, L.N.
登録日1990-11-13
公開日1992-10-15
最終更新日2017-11-29
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Structural mechanism for glycogen phosphorylase control by phosphorylation and AMP.
J.Mol.Biol., 218, 1991
8GPB
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STRUCTURAL MECHANISM FOR GLYCOGEN PHOSPHORYLASE CONTROL BY PHOSPHORYLATION AND AMP
分子名称:GLYCOGEN PHOSPHORYLASE B, PYRIDOXAL-5'-PHOSPHATE, ADENOSINE MONOPHOSPHATE
著者Barford, D., Hu, S.-H., Johnson, L.N.
登録日1990-11-13
公開日1992-10-15
最終更新日2017-11-29
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Structural mechanism for glycogen phosphorylase control by phosphorylation and AMP.
J.Mol.Biol., 218, 1991
9GPB
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THE ALLOSTERIC TRANSITION OF GLYCOGEN PHOSPHORYLASE
分子名称:GLYCOGEN PHOSPHORYLASE B, SULFATE ION, PYRIDOXAL-5'-PHOSPHATE
著者Barford, D., Johnson, L.N.
登録日1990-12-17
公開日1992-10-15
最終更新日2017-11-29
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献The allosteric transition of glycogen phosphorylase.
Nature, 340, 1989
2HNP
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CRYSTAL STRUCTURE OF HUMAN PROTEIN TYROSINE PHOSPHATASE 1B
分子名称:PROTEIN-TYROSINE PHOSPHATASE-1B
著者Barford, D., Flint, A.J., Tonks, N.K.
登録日1994-09-19
公開日1994-12-20
最終更新日2017-11-29
実験手法X-RAY DIFFRACTION (2.85 Å)
主引用文献Crystal structure of human protein tyrosine phosphatase 1B.
Science, 263, 1994
2HNQ
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CRYSTAL STRUCTURE OF HUMAN PROTEIN TYROSINE PHOSPHATASE 1B
分子名称:PROTEIN-TYROSINE PHOSPHATASE-1B, TUNGSTATE(VI)ION
著者Barford, D., Flint, A.J., Tonks, N.K.
登録日1994-09-28
公開日1994-12-20
最終更新日2017-11-29
実験手法X-RAY DIFFRACTION (2.85 Å)
主引用文献Crystal structure of human protein tyrosine phosphatase 1B.
Science, 263, 1994
1PTT
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CRYSTAL STRUCTURE OF PROTEIN TYROSINE PHOSPHATASE 1B COMPLEXED WITH PHOSPHOTYROSINE-CONTAINING TETRA-PEPTIDE (AC-DEPYL-NH2)
分子名称:PROTEIN TYROSINE PHOSPHATASE 1B, PHOSPHOTYROSINE-CONTAINING TETRA-PEPTIDE
著者Barford, D., Jia, Z.
登録日1995-04-21
公開日1996-08-01
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Structural basis for phosphotyrosine peptide recognition by protein tyrosine phosphatase 1B.
Science, 268, 1995
1PTU
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CRYSTAL STRUCTURE OF PROTEIN TYROSINE PHOSPHATASE 1B COMPLEXED WITH PHOSPHOTYROSINE-CONTAINING HEXA-PEPTIDE (DADEPYL-NH2)
分子名称:PROTEIN TYROSINE PHOSPHATASE 1B, PHOSPHOTYROSINE-CONTAINING HEXA-PEPTIDE
著者Barford, D., Jia, Z.
登録日1995-04-21
公開日1996-08-01
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Structural basis for phosphotyrosine peptide recognition by protein tyrosine phosphatase 1B.
Science, 268, 1995
1PTV
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CRYSTAL STRUCTURE OF PROTEIN TYROSINE PHOSPHATASE 1B COMPLEXED WITH PHOSPHOTYROSINE
分子名称:PROTEIN TYROSINE PHOSPHATASE 1B, O-PHOSPHOTYROSINE
著者Barford, D., Jia, Z.
登録日1995-04-21
公開日1996-08-01
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Structural basis for phosphotyrosine peptide recognition by protein tyrosine phosphatase 1B.
Science, 268, 1995
1GZK
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MOLECULAR MECHANISM FOR THE REGULATION OF PROTEIN KINASE B/AKT BY HYDROPHOBIC MOTIF PHOSPHORYLATION
分子名称:RAC-BETA SERINE/THREONINE PROTEIN KINASE
著者Barford, D., Yang, J., Hemmings, B.A.
登録日2002-05-23
公開日2003-05-22
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Molecular Mechanism for the Regulation of Protein Kinase B/Akt by Hydrophobic Motif Phosphorylation
Mol.Cell, 9, 2002
1GZN
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STRUCTURE OF PKB KINASE DOMAIN
分子名称:RAC-BETA SERINE/THREONINE PROTEIN KINASE
著者Barford, D., Yang, J., Hemmings, B.A.
登録日2002-05-24
公開日2003-05-22
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Molecular Mechanism for the Regulation of Protein Kinase B/Akt by Hydrophobic Motif Phosphorylation
Mol.Cell, 9, 2002
1GZO
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STRUCTURE OF PROTEIN KINASE B UNPHOSPHORYLATED
分子名称:RAC-BETA SERINE/THREONINE PROTEIN KINASE
著者Barford, D., Yang, J., Hemmings, B.A.
登録日2002-05-24
公開日2003-05-22
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.75 Å)
主引用文献Molecular Mechanism for the Regulation of Protein Kinase B/Akt by Hydrophobic Motif Phosphorylation
Mol.Cell, 9, 2002
1UWH
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THE COMPLEX OF WILD TYPE B-RAF AND BAY439006.
分子名称:B-RAF PROTO-ONCOGENE SERINE/THREONINE-PROTEIN KINASE, 4-{4-[({[4-CHLORO-3-(TRIFLUOROMETHYL)PHENYL]AMINO}CARBONYL)AMINO]PHENOXY}-N-METHYLPYRIDINE-2-CARBOXAMIDE, CHLORIDE ION
著者Barford, D., Roe, S.M., Wan, P.T.C., Cancer Genome Project
登録日2004-02-05
公開日2004-03-19
最終更新日2018-01-17
実験手法X-RAY DIFFRACTION (2.95 Å)
主引用文献Mechanism of Activation of the Raf-Erk Signaling Pathway by Oncogenic Mutations of B-Raf
Cell(Cambridge,Mass.), 116, 2004
1UWJ
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THE COMPLEX OF MUTANT V599E B-RAF AND BAY439006.
分子名称:B-RAF PROTO-ONCOGENE SERINE/THREONINE-PROTEIN KINASE, 4-{4-[({[4-CHLORO-3-(TRIFLUOROMETHYL)PHENYL]AMINO}CARBONYL)AMINO]PHENOXY}-N-METHYLPYRIDINE-2-CARBOXAMIDE
著者Barford, D., Roe, S.M., Wan, P.T.C., Cancer Genome Project
登録日2004-02-05
公開日2004-03-19
最終更新日2018-01-17
実験手法X-RAY DIFFRACTION (3.5 Å)
主引用文献Mechanism of Activation of the Raf-Erk Signaling Pathway by Oncogenic Mutations of B-Raf
Cell(Cambridge,Mass.), 116, 2004
1WAO
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PP5 STRUCTURE
分子名称:SERINE/THREONINE PROTEIN PHOSPHATASE 5, MANGANESE (II) ION
著者Barford, D.
登録日2004-10-27
公開日2005-02-22
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Molecular Basis for Tpr Domain-Mediated Regulation of Protein Phosphatase 5
Embo J., 24, 2005
3KAE
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CDC27 N-TERMINUS
分子名称:Possible protein of nuclear scaffold, GLYCEROL, CHLORIDE ION, ...
著者Barford, D., Zhang, Z., Roe, S.M.
登録日2009-10-19
公開日2010-03-23
最終更新日2014-02-26
実験手法X-RAY DIFFRACTION (2.298 Å)
主引用文献Molecular structure of the N-terminal domain of the APC/C subunit Cdc27 reveals a homo-dimeric tetratricopeptide repeat architecture
J.Mol.Biol., 397, 2010
3ZV2
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HUMAN PROTEIN-TYROSINE PHOSPHATASE 1B C215A, S216A MUTANT
分子名称:Tyrosine-protein phosphatase non-receptor type 1
著者Barford, D., Salmeen, A., Tonks, N.K.
登録日2011-07-22
公開日2011-08-31
最終更新日2018-07-25
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Conformation-sensing antibodies stabilize the oxidized form of PTP1B and inhibit its phosphatase activity.
Cell, 147, 2011
1ABB
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CONTROL OF PHOSPHORYLASE B CONFORMATION BY A MODIFIED COFACTOR: CRYSTALLOGRAPHIC STUDIES ON R-STATE GLYCOGEN PHOSPHORYLASE RECONSTITUTED WITH PYRIDOXAL 5'-DIPHOSPHATE
分子名称:GLYCOGEN PHOSPHORYLASE B, SULFATE ION, PYRIDOXAL-5'-DIPHOSPHATE, ...
著者Leonidas, D.D., Oikonomakos, N.G., Papageorgiou, A.C., Acharya, K.R., Barford, D., Johnson, L.N.
登録日1992-04-09
公開日1993-10-31
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Control of phosphorylase b conformation by a modified cofactor: crystallographic studies on R-state glycogen phosphorylase reconstituted with pyridoxal 5'-diphosphate.
Protein Sci., 1, 1992
1BZC
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HUMAN PTP1B CATALYTIC DOMAIN COMPLEXED WITH TPI
分子名称:PROTEIN (PROTEIN-TYROSINE-PHOSPHATASE), 4-CARBAMOYL-4-{[6-(DIFLUORO-PHOSPHONO-METHYL)-NAPHTHALENE-2-CARBONYL]-AMINO}-BUTYRIC ACID
著者Groves, M.R., Yao, Z.J., Jr Burke, T.R., Barford, D.
登録日1998-10-27
公開日1999-02-16
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.35 Å)
主引用文献Structural basis for inhibition of the protein tyrosine phosphatase 1B by phosphotyrosine peptide mimetics.
Biochemistry, 37, 1998
1BZH
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CYCLIC PEPTIDE INHIBITOR OF HUMAN PTP1B
分子名称:PROTEIN (PROTEIN-TYROSINE-PHOSPHATASE 1B), PROTEIN (PROTEIN-TYROSINE-PHOSPHATASE 1B INHIBITOR)
著者Groves, M.R., Yao, Z.J., Burke Jr., T.R., Barford, D.
登録日1998-10-28
公開日1999-02-16
最終更新日2018-12-26
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Structural basis for inhibition of the protein tyrosine phosphatase 1B by phosphotyrosine peptide mimetics.
Biochemistry, 37, 1998
2BGG
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THE STRUCTURE OF A PIWI PROTEIN FROM ARCHAEOGLOBUS FULGIDUS COMPLEXED WITH A 16NT SIRNA DUPLEX.
分子名称:PROTEIN AF1318, 5'-R(*UP*UP*CP*GP*AP*CP*GP*CP)-3', 5'-R(*GP*UP*CP*GP*AP*AP*UP*UP)-3', ...
著者Parker, J.S., Roe, S.M., Barford, D.
登録日2004-12-22
公開日2005-03-31
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Structural Insights Into Mrna Recognition from a Piwi Domain-Sirna Guide Complex
Nature, 434, 2005
2JF5
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CRYSTAL STRUCTURE OF LYS63-LINKED DI-UBIQUITIN
分子名称:UBIQUITIN, CADMIUM ION, MAGNESIUM ION, ...
著者Komander, D., Odenwaelder, P., Barford, D.
登録日2007-01-26
公開日2008-02-05
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Molecular Discrimination of Structurally Equivalent Lys 63-Linked and Linear Polyubiquitin Chains.
Embo Rep., 10, 2009
2V55
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MECHANISM OF MULTI-SITE PHOSPHORYLATION FROM A ROCK-I:RHOE COMPLEX STRUCTURE
分子名称:RHO-ASSOCIATED PROTEIN KINASE 1, RHO-RELATED GTP-BINDING PROTEIN RHOE, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, ...
著者Komander, D., Garg, R., Wan, P.T.C., Ridley, A.J., Barford, D.
登録日2008-10-01
公開日2008-11-04
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (3.705 Å)
主引用文献Mechanism of Multi-Site Phosphorylation from a Rock-I:Rhoe Complex Structure.
Embo J., 27, 2008
2VFJ
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STRUCTURE OF THE A20 OVARIAN TUMOUR (OTU) DOMAIN
分子名称:TUMOR NECROSIS FACTOR, SULFATE ION, MAGNESIUM ION
著者Komander, D., Barford, D.
登録日2007-11-04
公開日2007-12-04
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献Structure of the A20 Otu Domain and Mechanistic Insights Into Deubiquitination
Biochem.J., 409, 2008
2VHF
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STRUCTURE OF THE CYLD USP DOMAIN
分子名称:UBIQUITIN CARBOXYL-TERMINAL HYDROLASE CYLD, ZINC ION
著者Komander, D., Lord, C.J., Scheel, H., Swift, S., Hofmann, K., Ashworth, A., Barford, D.
登録日2007-11-21
公開日2008-03-11
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献The Structure of the Cyld Usp Domain Explains its Specificity for Lys63-Linked Polyubiquitin and Reveals a B-Box Module
Mol.Cell.Biol., 29, 2008