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4UU4
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BU of 4uu4 by Molmil
Crystal structure of LptH, the LptA homologous periplasmic component of the conserved lipopolysaccharide transport device from Pseudomonas aeruginosa
Descriptor: PERIPLASMIC LIPOPOLYSACCHARIDE TRANSPORT PROTEIN LPTH
Authors:Bollati, M, Villa, R, Gourlay, L.J, Barbiroli, A, Deho, G, Benedet, M, Polissi, A, Martorana, A, Sperandeo, P, Bolognesi, M, Nardini, M.
Deposit date:2014-07-24
Release date:2015-03-25
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.751 Å)
Cite:Crystal Structure of Lpth, the Periplasmic Component of the Lipopolysaccharide Transport Machinery from Pseudomonas Aeruginosa.
FEBS J., 282, 2015
6Y2K
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BU of 6y2k by Molmil
Crystal structure of beta-galactosidase from the psychrophilic Marinomonas ef1
Descriptor: CHLORIDE ION, GLYCEROL, beta-galactosidase
Authors:Mangiagalli, M, Lapi, M, Maione, S, Orlando, M, Brocca, S, Pesce, A, Barbiroli, A, Pucciarelli, S, Camilloni, C, Lotti, M.
Deposit date:2020-02-16
Release date:2020-05-20
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:The co-existence of cold activity and thermal stability in an Antarctic GH42 beta-galactosidase relies on its hexameric quaternary arrangement.
Febs J., 288, 2021
5L8S
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BU of 5l8s by Molmil
The crystal structure of a cold-adapted acylaminoacyl peptidase reveals a novel quaternary architecture based on the arm-exchange mechanism
Descriptor: Amino acyl peptidase, SULFATE ION
Authors:Brocca, S, Ferrari, C, Barbiroli, A, Pesce, A, Lotti, M, Nardini, M.
Deposit date:2016-06-08
Release date:2016-11-16
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:A bacterial acyl aminoacyl peptidase couples flexibility and stability as a result of cold adaptation.
FEBS J., 283, 2016
6I8C
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BU of 6i8c by Molmil
Crystal structure of the murine beta-2-microglobulin.
Descriptor: Beta-2-microglobulin, TRIETHYLENE GLYCOL
Authors:Achour, A, Sandalova, T, Ricagno, S, Sun, R.
Deposit date:2018-11-20
Release date:2019-10-02
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (1.92 Å)
Cite:Biochemical and biophysical comparison of human and mouse beta-2 microglobulin reveals the molecular determinants of low amyloid propensity.
Febs J., 287, 2020
6GRZ
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BU of 6grz by Molmil
Crystal structure of the light chain dimer mH6
Descriptor: GLYCEROL, mH6
Authors:Maritan, M, Ricagno, S, Ambrosetti, A, Oberti, L.
Deposit date:2018-06-13
Release date:2019-06-12
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Inherent Biophysical Properties Modulate the Toxicity of Soluble Amyloidogenic Light Chains
J.Mol.Biol., 2020
6H1F
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BU of 6h1f by Molmil
Structure of the nanobody-stabilized gelsolin D187N variant (second domain)
Descriptor: Gelsolin, THIOCYANATE ION, gelsolin nanobody, ...
Authors:Hassan, A, Milani, M, Mastrangelo, E, de Rosa, M.
Deposit date:2018-07-11
Release date:2019-01-23
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Nanobody interaction unveils structure, dynamics and proteotoxicity of the Finnish-type amyloidogenic gelsolin variant.
Biochim Biophys Acta Mol Basis Dis, 1865, 2019
7ZS6
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BU of 7zs6 by Molmil
Crystal structure of Apis mellifera RidA
Descriptor: 1,2-ETHANEDIOL, MAGNESIUM ION, Reactive intermediate deaminase A, ...
Authors:Visentin, C, Rizzi, G, Ricagno, S.
Deposit date:2022-05-06
Release date:2022-07-13
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (1.31 Å)
Cite:Apis mellifera RidA, a novel member of the canonical YigF/YER057c/UK114 imine deiminase superfamily of enzymes pre-empting metabolic damage.
Biochem.Biophys.Res.Commun., 616, 2022
4L3C
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BU of 4l3c by Molmil
Structure of HLA-A2 in complex with D76N b2m mutant and NY-ESO1 double mutant
Descriptor: Beta-2-microglobulin, CHLORIDE ION, GLYCEROL, ...
Authors:Halabelian, L, Giorgetti, S, Bellotti, V, Bolognesi, M, Ricagno, S.
Deposit date:2013-06-05
Release date:2013-12-25
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.64 Å)
Cite:Class I Major Histocompatibility Complex, the Trojan Horse for Secretion of Amyloidogenic beta 2-Microglobulin.
J.Biol.Chem., 289, 2014
4L29
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BU of 4l29 by Molmil
Structure of wtMHC class I with NY-ESO1 double mutant
Descriptor: Beta-2-microglobulin, CHLORIDE ION, GLYCEROL, ...
Authors:Halabelian, L, Giorgetti, S, Bellotti, V, Bolognesi, M, Ricagno, S.
Deposit date:2013-06-04
Release date:2013-12-25
Last modified:2014-02-26
Method:X-RAY DIFFRACTION (3.09 Å)
Cite:Class I Major Histocompatibility Complex, the Trojan Horse for Secretion of Amyloidogenic beta 2-Microglobulin.
J.Biol.Chem., 289, 2014
7P0A
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BU of 7p0a by Molmil
CRYSTAL STRUCTURE OF THE MURINE CLASS I MAJOR HISTOCOMPATIBILITY COMPLEX H-2DB IN COMPLEX WITH LCMV-DERIVED GP33 PEPTIDE with D-AMINOACID (p3P6f)
Descriptor: Beta-2-microglobulin, CHLORIDE ION, H-2 class I histocompatibility antigen, ...
Authors:Broggini, L, Ricagno, S.
Deposit date:2021-06-29
Release date:2022-03-23
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (2.429 Å)
Cite:l- to d-Amino Acid Substitution in the Immunodominant LCMV-Derived Epitope gp33 Highlights the Sensitivity of the TCR Recognition Mechanism for the MHC/Peptide Structure and Dynamics.
Acs Omega, 7, 2022
7P0T
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BU of 7p0t by Molmil
CRYSTAL STRUCTURE OF THE MURINE CLASS I MAJOR HISTOCOMPATIBILITY COMPLEX H-2DB IN COMPLEX WITH LCMV-DERIVED GP33 PEPTIDE with D-AMINOACID
Descriptor: Beta-2-microglobulin, CHLORIDE ION, Derived peptide gp33-41 from LCMV, ...
Authors:Broggini, L, Ricagno, S.
Deposit date:2021-06-30
Release date:2022-03-23
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (2.605 Å)
Cite:l- to d-Amino Acid Substitution in the Immunodominant LCMV-Derived Epitope gp33 Highlights the Sensitivity of the TCR Recognition Mechanism for the MHC/Peptide Structure and Dynamics.
Acs Omega, 7, 2022
7P2B
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BU of 7p2b by Molmil
Crystal structure of human gelsolin amyloid mutant A551P
Descriptor: CHLORIDE ION, GLYCEROL, Gelsolin, ...
Authors:Bollati, M, de Rosa, M.
Deposit date:2021-07-05
Release date:2022-05-18
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (3 Å)
Cite:A novel hotspot of gelsolin instability triggers an alternative mechanism of amyloid aggregation.
Comput Struct Biotechnol J, 19, 2021
3NA4
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BU of 3na4 by Molmil
D53P beta-2 microglobulin mutant
Descriptor: 2-{2-[2-(2-{2-[2-(2-ETHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHOXY)-ETHOXY]-ETHOXY}-ETHANOL, Beta-2-microglobulin
Authors:Azinas, S, Ricagno, S, Bolognesi, M.
Deposit date:2010-06-01
Release date:2011-06-01
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:D-strand perturbation and amyloid propensity in beta-2 microglobulin
Febs J., 278, 2011
6R85
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BU of 6r85 by Molmil
Structure of Arabidopsis thaliana GLR3.3 ligand-binding domain in complex with L-glutamate
Descriptor: 1,2-ETHANEDIOL, GLUTAMIC ACID, Glutamate receptor 3.3,Glutamate receptor 3.3, ...
Authors:Alfieri, A, Pederzoli, R, Costa, A.
Deposit date:2019-03-31
Release date:2020-01-01
Last modified:2020-01-15
Method:X-RAY DIFFRACTION (2 Å)
Cite:The structural bases for agonist diversity in anArabidopsis thalianaglutamate receptor-like channel.
Proc.Natl.Acad.Sci.USA, 117, 2020
6R8A
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BU of 6r8a by Molmil
Structure of Arabidopsis thaliana GLR3.3 ligand-binding domain in complex with L-methionine
Descriptor: Glutamate receptor 3.3,Glutamate receptor 3.3, METHIONINE, SODIUM ION, ...
Authors:Alfieri, A, Pederzoli, R, Costa, A.
Deposit date:2019-04-01
Release date:2020-01-01
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:The structural bases for agonist diversity in anArabidopsis thalianaglutamate receptor-like channel.
Proc.Natl.Acad.Sci.USA, 117, 2020
6R88
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BU of 6r88 by Molmil
Structure of Arabidopsis thaliana GLR3.3 ligand-binding domain in complex with glycine
Descriptor: CHLORIDE ION, GLYCEROL, GLYCINE, ...
Authors:Alfieri, A, Pederzoli, R, Costa, A.
Deposit date:2019-04-01
Release date:2020-01-01
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:The structural bases for agonist diversity in anArabidopsis thalianaglutamate receptor-like channel.
Proc.Natl.Acad.Sci.USA, 117, 2020
6R89
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BU of 6r89 by Molmil
Structure of Arabidopsis thaliana GLR3.3 ligand-binding domain in complex with L-cysteine
Descriptor: CHLORIDE ION, CYSTEINE, GLYCEROL, ...
Authors:Alfieri, A, Pederzoli, R, Costa, A.
Deposit date:2019-04-01
Release date:2020-01-01
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:The structural bases for agonist diversity in anArabidopsis thalianaglutamate receptor-like channel.
Proc.Natl.Acad.Sci.USA, 117, 2020
6Q9Z
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BU of 6q9z by Molmil
Crystal structure of the pathological G167R variant of calcium-free human gelsolin,
Descriptor: GLYCEROL, Gelsolin, SULFATE ION
Authors:Boni, F, Scalone, E, Milani, M, Eloise, M, de Rosa, M.
Deposit date:2018-12-18
Release date:2019-11-27
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (3.8 Å)
Cite:The structure of N184K amyloidogenic variant of gelsolin highlights the role of the H-bond network for protein stability and aggregation properties.
Eur.Biophys.J., 49, 2020
6QBF
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BU of 6qbf by Molmil
Crystal structure of the pathological D187N variant of calcium-free human gelsolin.
Descriptor: GLYCEROL, Gelsolin, SODIUM ION, ...
Authors:Scalone, E, Boni, F, Milani, M, Eloise, M, de Rosa, M.
Deposit date:2018-12-21
Release date:2019-11-27
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (3.499 Å)
Cite:The structure of N184K amyloidogenic variant of gelsolin highlights the role of the H-bond network for protein stability and aggregation properties.
Eur.Biophys.J., 49, 2020
6Q9R
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BU of 6q9r by Molmil
Crystal structure of the pathological N184K variant of calcium-free human gelsolin
Descriptor: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, CHLORIDE ION, GLYCEROL, ...
Authors:Scalone, E, Boni, F, Milani, M, Eloise, M, de Rosa, M.
Deposit date:2018-12-18
Release date:2019-11-27
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (2.73 Å)
Cite:The structure of N184K amyloidogenic variant of gelsolin highlights the role of the H-bond network for protein stability and aggregation properties.
Eur.Biophys.J., 49, 2020
4RA3
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BU of 4ra3 by Molmil
Crystal structure of dimeric S33C beta-2 microglobulin mutant in complex with Thioflavin (ThT) at 2.8 Angstrom resolution
Descriptor: 2-[4-(dimethylamino)phenyl]-3,6-dimethyl-1,3-benzothiazol-3-ium, Beta-2-microglobulin
Authors:Halabelian, L, Bolognesi, M, Ricagno, S.
Deposit date:2014-09-09
Release date:2015-09-09
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:A covalent homodimer probing early oligomers along amyloid aggregation.
Sci Rep, 5, 2015
4R9H
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BU of 4r9h by Molmil
Crystal structure of dimeric S33C beta-2 microglobulin mutant at 1.9 Angstrom resolution
Descriptor: Beta-2-microglobulin
Authors:Halabelian, L, Bolognesi, M, Ricagno, S.
Deposit date:2014-09-05
Release date:2015-09-09
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:A covalent homodimer probing early oligomers along amyloid aggregation.
Sci Rep, 5, 2015
4RAH
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BU of 4rah by Molmil
Crystal structure of dimeric S33C beta-2 microglobulin mutant at 1.4 Angstrom resolution
Descriptor: Beta-2-microglobulin
Authors:Halabelian, L, Bolognesi, M, Ricagno, S.
Deposit date:2014-09-10
Release date:2015-09-16
Last modified:2015-11-04
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:A covalent homodimer probing early oligomers along amyloid aggregation.
Sci Rep, 5, 2015
5O7G
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BU of 5o7g by Molmil
The crystal structure of a highly thermostable carboxyl esterase from Bacillus coagulans
Descriptor: Alpha/beta hydrolase family protein
Authors:Gourlay, L.J.
Deposit date:2017-06-08
Release date:2017-12-06
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:A stereospecific carboxyl esterase from Bacillus coagulans hosting nonlipase activity within a lipase-like fold.
FEBS J., 285, 2018
5OLU
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BU of 5olu by Molmil
The crystal structure of a highly thermostable carboxyl esterase from Bacillus coagulans in complex with glycerol
Descriptor: ACETATE ION, Alpha/beta hydrolase family protein, CHLORIDE ION, ...
Authors:Gourlay, L.J, Nakhnoukh, C, Bolognesi, M.
Deposit date:2017-07-28
Release date:2017-12-06
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:A stereospecific carboxyl esterase from Bacillus coagulans hosting nonlipase activity within a lipase-like fold.
FEBS J., 285, 2018

 

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