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6N13
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BU of 6n13 by Molmil
UbcH7-Ub Complex with R0RBR Parkin and phosphoubiquitin
Descriptor: E3 ubiquitin-protein ligase parkin, Ubiquitin-conjugating enzyme E2 L3, ZINC ION, ...
Authors:Condos, T.E.C, Dunkerley, K.M, Freeman, E.A, Barber, K.R, Aguirre, J.D, Chaugule, V.K, Xiao, Y, Konermann, L, Walden, H, Shaw, G.S.
Deposit date:2018-11-08
Release date:2018-11-28
Last modified:2020-01-08
Method:SOLUTION NMR
Cite:Synergistic recruitment of UbcH7~Ub and phosphorylated Ubl domain triggers parkin activation.
EMBO J., 37, 2018
5C23
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BU of 5c23 by Molmil
Parkin (S65DUblR0RBR)
Descriptor: CHLORIDE ION, E3 ubiquitin-protein ligase parkin, GLYCEROL, ...
Authors:Kumar, A, Aguirre, J.D, Condos, T.E.C, Martinez-Torres, R.J, Chaugule, V.K, Toth, R, Sundaramoorthy, R, Mercier, P, Knebel, A, Spratt, D.E, Barber, K.R, Shaw, G.S, Walden, H.
Deposit date:2015-06-15
Release date:2015-07-29
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.37 Å)
Cite:Disruption of the autoinhibited state primes the E3 ligase parkin for activation and catalysis.
Embo J., 34, 2015
5C1Z
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BU of 5c1z by Molmil
Parkin (UblR0RBR)
Descriptor: CHLORIDE ION, E3 ubiquitin-protein ligase parkin, GLYCEROL, ...
Authors:kumar, A, Aguirre, J.D, Condos, T.E.C, Martinez-Torres, R.J, Chaugule, V.K, Toth, R, Sundaramoorthy, R, Mercier, P, Knebel, A, Spratt, D.E, Barber, K.R, Shaw, G.S, Walden, H.
Deposit date:2015-06-15
Release date:2015-07-29
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (1.79 Å)
Cite:Disruption of the autoinhibited state primes the E3 ligase parkin for activation and catalysis.
Embo J., 34, 2015
4Q5E
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BU of 4q5e by Molmil
Shigella Effector Kinase OspG bound to E2-Ub UbcH7-Ub Conjugate
Descriptor: Polyubiquitin, Protein kinase OspG, Ubiquitin-conjugating enzyme E2 L3
Authors:Cygler, M, Grishin, A.M, Montreal-Kingston Bacterial Structural Genomics Initiative (BSGI)
Deposit date:2014-04-16
Release date:2014-07-02
Last modified:2017-11-22
Method:X-RAY DIFFRACTION (1.869 Å)
Cite:Structural Basis for the Inhibition of Host Protein Ubiquitination by Shigella Effector Kinase OspG.
Structure, 22, 2014
5N2W
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BU of 5n2w by Molmil
WT-Parkin and pUB complex
Descriptor: CHLORIDE ION, E3 ubiquitin-protein ligase parkin,E3 ubiquitin-protein ligase parkin, Polyubiquitin-B, ...
Authors:Kumar, A, Chaugule, V.K, Johnson, C, Toth, R, Sundaramoorthy, R, Knebel, A, Walden, H.
Deposit date:2017-02-08
Release date:2017-04-19
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2.68 Å)
Cite:Parkin-phosphoubiquitin complex reveals cryptic ubiquitin-binding site required for RBR ligase activity.
Nat. Struct. Mol. Biol., 24, 2017
5N38
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BU of 5n38 by Molmil
S65DParkin and pUB complex
Descriptor: CHLORIDE ION, DI(HYDROXYETHYL)ETHER, E3 ubiquitin-protein ligase parkin,E3 ubiquitin-protein ligase parkin, ...
Authors:Kumar, A, Chaugule, V.K, Johnson, C, Toth, R, Sundaramoorthy, R, Knebel, A, Walden, H.
Deposit date:2017-02-08
Release date:2017-04-19
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Parkin-phosphoubiquitin complex reveals cryptic ubiquitin-binding site required for RBR ligase activity.
Nat. Struct. Mol. Biol., 24, 2017
2LGY
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BU of 2lgy by Molmil
Ubiquitin-like domain from HOIL-1
Descriptor: RanBP-type and C3HC4-type zinc finger-containing protein 1
Authors:Beasley, S.A, Shaw, G.S.
Deposit date:2011-08-03
Release date:2012-06-20
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:Solution structure of the E3 ligase HOIL-1 Ubl domain.
Protein Sci., 21, 2012
2LWR
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BU of 2lwr by Molmil
Solution Structure of RING2 Domain from Parkin
Descriptor: SD01679p, ZINC ION
Authors:Mercier, P, Spratt, D.E, Manczyk, N, Shaw, G.S.
Deposit date:2012-08-06
Release date:2013-06-12
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:A molecular explanation for the recessive nature of parkin-linked Parkinson's disease.
Nat Commun, 4, 2013
2M48
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BU of 2m48 by Molmil
Solution Structure of IBR-RING2 Tandem Domain from Parkin
Descriptor: E3 UBIQUITIN-PROTEIN LIGASE PARKIN, ZINC ION
Authors:Noh, Y.J, Mercier, P, Spratt, D.E, Shaw, G.S.
Deposit date:2013-01-30
Release date:2013-05-15
Last modified:2024-03-13
Method:SOLUTION NMR
Cite:A molecular explanation for the recessive nature of parkin-linked Parkinson's disease.
Nat Commun, 4, 2013
1FXT
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BU of 1fxt by Molmil
STRUCTURE OF A CONJUGATING ENZYME-UBIQUITIN THIOLESTER COMPLEX
Descriptor: UBIQUITIN, UBIQUITIN-CONJUGATING ENZYME E2-24 KDA
Authors:Hamilton, K.S, Shaw, G.S, Williams, R.S, Huzil, J.T, McKenna, S, Ptak, C, Glover, M, Ellison, M.J.
Deposit date:2000-09-26
Release date:2001-10-10
Last modified:2022-02-23
Method:SOLUTION NMR
Cite:Structure of a conjugating enzyme-ubiquitin thiolester intermediate reveals a novel role for the ubiquitin tail.
Structure, 9, 2001
1FZY
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BU of 1fzy by Molmil
CRYSTAL STRUCTURE OF SACCHAROMYCES CEREVISIAE UBIQUITIN CONJUGATING ENZYME 1
Descriptor: UBIQUITIN-CONJUGATING ENZYME E2-24 KDA
Authors:Glover, M, Williams, R.S.
Deposit date:2000-10-04
Release date:2001-10-04
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structure of a conjugating enzyme-ubiquitin thiolester intermediate reveals a novel role for the ubiquitin tail.
Structure, 9, 2001
4Q5H
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BU of 4q5h by Molmil
Shigella Effector Kinase OspG bound to AMPPNP and E2-Ub UbcH7-Ub Conjugate
Descriptor: MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, Polyubiquitin, ...
Authors:Cygler, M, Grishin, A.M, Montreal-Kingston Bacterial Structural Genomics Initiative (BSGI)
Deposit date:2014-04-16
Release date:2014-07-02
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.999 Å)
Cite:Structural Basis for the Inhibition of Host Protein Ubiquitination by Shigella Effector Kinase OspG.
Structure, 22, 2014
4DRW
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BU of 4drw by Molmil
Crystal Structure of the Ternary Complex between S100A10, an Annexin A2 N-terminal Peptide and an AHNAK Peptide
Descriptor: Neuroblast differentiation-associated protein AHNAK, Protein S100-A10/Annexin A2 chimeric protein
Authors:Rezvanpour, A, Lee, T.-W, Junop, M.S, Shaw, G.S.
Deposit date:2012-02-17
Release date:2012-10-24
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (3.5 Å)
Cite:Structure of an asymmetric ternary protein complex provides insight for membrane interaction.
Structure, 20, 2012

217705

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