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4DGI
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STRUCTURE OF POM1 FAB FRAGMENT COMPLEXED WITH HUMAN PRPC FRAGMENT 120-230
Descriptor:Major prion protein, POM1 Fab Heavy chain, POM1 Fab Light chain, ...
Authors:Baral, P.K., Wieland, B., Swayampakula, M., James, M.N.
Deposit date:2012-01-26
Release date:2012-10-31
Last modified:2013-01-23
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Structural studies on the folded domain of the human prion protein bound to the Fab fragment of the antibody POM1.
Acta Crystallogr.,Sect.D, 68, 2012
3CSK
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STRUCTURE OF DPP III FROM SACCHAROMYCES CEREVISIAE
Descriptor:Probable dipeptidyl-peptidase 3, ZINC ION, MAGNESIUM ION
Authors:Baral, P.K., Jajcanin, N., Deller, S., Macheroux, P., Abramic, M., Gruber, K.
Deposit date:2008-04-10
Release date:2008-06-10
Last modified:2014-02-12
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:The first structure of dipeptidyl-peptidase III provides insight into the catalytic mechanism and mode of substrate binding.
J.Biol.Chem., 283, 2008
4MA7
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CRYSTAL STRUCTURE OF MOUSE PRION PROTEIN COMPLEXED WITH PROMAZINE
Descriptor:Major prion protein, POM1 heavy chain, POM1 light chain, ...
Authors:Baral, P.K., Swayampakula, M., James, M.N.G.
Deposit date:2013-08-15
Release date:2014-01-22
Last modified:2014-02-26
Method:X-RAY DIFFRACTION (1.97 Å)
Cite:Structural basis of prion inhibition by phenothiazine compounds.
Structure, 22, 2014
4MA8
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CRYSTAL STRUCTURE OF MOUSE PRION PROTEIN COMPLEXED WITH CHLORPROMAZINE
Descriptor:Major prion protein, POM1 heavy chain, POM1 light chain, ...
Authors:Baral, P.K., Swayampakula, M., James, M.N.G.
Deposit date:2013-08-15
Release date:2014-01-22
Last modified:2014-02-26
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structural basis of prion inhibition by phenothiazine compounds.
Structure, 22, 2014
4YX2
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CRYSTAL STRUCTURE OF BOVINE PRION PROTEIN COMPLEXED WITH POM1 FAB
Descriptor:Major prion protein, POM1 FAB HEAVY CHAIN, POM1 FAB LIGHT CHAIN
Authors:Baral, P.K., Swayampakula, M., James, M.N.G.
Deposit date:2015-03-22
Release date:2015-09-23
Last modified:2015-10-14
Method:X-RAY DIFFRACTION (2.194 Å)
Cite:X-ray structural and molecular dynamical studies of the globular domains of cow, deer, elk and Syrian hamster prion proteins.
J.Struct.Biol., 192, 2015
4YXH
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CRYSTAL STRUCTURE OF DEER PRION PROTEIN COMPLEXED WITH POM1 FAB
Descriptor:Major prion protein, POM1 FAB HEAVY CHAIN, POM1 FAB LIGHT CHAIN, ...
Authors:Baral, P.K., Swayampakula, M., James, M.N.G.
Deposit date:2015-03-23
Release date:2015-09-23
Last modified:2015-10-14
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:X-ray structural and molecular dynamical studies of the globular domains of cow, deer, elk and Syrian hamster prion proteins.
J.Struct.Biol., 192, 2015
4YXK
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CRYSTAL STRUCTURE OF ELK PRION PROTEIN COMPLEXED WITH POM1 FAB
Descriptor:Major prion protein, POM1 FAB HEAVY CHAIN, POM1 FAB LIGHT CHAIN, ...
Authors:Baral, P.K., Swayampakula, M., James, M.N.G.
Deposit date:2015-03-23
Release date:2015-09-23
Last modified:2015-10-14
Method:X-RAY DIFFRACTION (2.805 Å)
Cite:X-ray structural and molecular dynamical studies of the globular domains of cow, deer, elk and Syrian hamster prion proteins.
J.Struct.Biol., 192, 2015
4YXL
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CRYSTAL STRUCTURE OF SYRIAN HAMSTER PRION PROTEIN COMPLEXED WITH POM1 FAB
Descriptor:Major prion protein, POM1 FAB HEAVY CHAIN, POM1 FAB LIGHT CHAIN, ...
Authors:Baral, P.K., Swayampakula, M., James, M.N.G.
Deposit date:2015-03-23
Release date:2015-09-23
Last modified:2015-10-14
Method:X-RAY DIFFRACTION (2.604 Å)
Cite:X-ray structural and molecular dynamical studies of the globular domains of cow, deer, elk and Syrian hamster prion proteins.
J.Struct.Biol., 192, 2015
6AQ7
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STRUCTURE OF POM6 FAB FRAGMENT COMPLEXED WITH MOUSE PRPC
Descriptor:Major prion protein, POM6 FAB Heavy CHAIN, POM6 FAB light CHAIN, ...
Authors:Baral, P.K., Swayampakula, M., James, M.N.G.
Deposit date:2017-08-18
Release date:2018-04-04
Last modified:2018-11-07
Method:X-RAY DIFFRACTION (1.83 Å)
Cite:Structural characterization of POM6 Fab and mouse prion protein complex identifies key regions for prions conformational conversion.
FEBS J., 285, 2018
4H88
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STRUCTURE OF POM1 FAB FRAGMENT COMPLEXED WITH MOUSE PRPC FRAGMENT 120-230
Descriptor:Major prion protein, POM1 FAB CHAIN H, POM1 FAB CHAIN L, ...
Authors:Baral, P.K., Wieland, B., Swayampakula, M., James, M.N.
Deposit date:2012-09-21
Release date:2013-07-31
Last modified:2013-09-18
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:The toxicity of antiprion antibodies is mediated by the flexible tail of the prion protein.
Nature, 501, 2013
4J8R
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STRUCTURE OF AN OCTAPEPTIDE REPEAT OF THE PRION PROTEIN BOUND TO THE POM2 FAB ANTIBODY FRAGMENT
Descriptor:Light chain of POM2 Fab, Heavy chain of POM2 Fab, Major prion protein
Authors:Swayampakula, M., Baral, P.K., Kav, N.N.V., Aguzzi, A., James, M.N.G.
Deposit date:2013-02-14
Release date:2013-05-22
Last modified:2014-11-26
Method:X-RAY DIFFRACTION (2.303 Å)
Cite:The crystal structure of an octapeptide repeat of the Prion protein in complex with a Fab fragment of the POM2 antibody.
Protein Sci., 22, 2013