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1AUA
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BU of 1aua by Molmil
PHOSPHATIDYLINOSITOL TRANSFER PROTEIN SEC14P FROM SACCHAROMYCES CEREVISIAE
Descriptor: PHOSPHATIDYLINOSITOL TRANSFER PROTEIN SEC14P, octyl beta-D-glucopyranoside
Authors:Sha, B, Phillips, S.E, Bankaitis, V.A, Luo, M.
Deposit date:1997-08-20
Release date:1997-12-24
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Crystal structure of the Saccharomyces cerevisiae phosphatidylinositol-transfer protein.
Nature, 391, 1998
3Q8G
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BU of 3q8g by Molmil
Resurrection of a functional phosphatidylinositol transfer protein from a pseudo-Sec14 scaffold by directed evolution
Descriptor: 1,2-dioleoyl-sn-glycero-3-phosphoethanolamine, CRAL-TRIO domain-containing protein YKL091C, GLYCEROL
Authors:Ortlund, E.A, Schaaf, G, Bankaitis, V.A.
Deposit date:2011-01-06
Release date:2011-02-23
Last modified:2023-05-31
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Resurrection of a functional phosphatidylinositol transfer protein from a pseudo-Sec14 scaffold by directed evolution.
Mol.Biol.Cell, 22, 2011
6W32
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Crystal structure of Sfh5
Descriptor: PROTOPORPHYRIN IX CONTAINING FE, Phosphatidylinositol transfer protein SFH5
Authors:Gulten, G, Khan, D, Aggarwal, A, Krieger, I, Sacchettini, J.C, Bankaitis, V.A.
Deposit date:2020-03-08
Release date:2020-11-25
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:A Sec14-like phosphatidylinositol transfer protein paralog defines a novel class of heme-binding proteins.
Elife, 9, 2020
6DII
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BU of 6dii by Molmil
Structure of Arabidopsis Fatty Acid Amide Hydrolase in Complex with methyl linolenyl fluorophosphonate
Descriptor: Fatty acid amide hydrolase, methyl-9Z,12Z,15Z-octadecatrienylphosphonofluoridate
Authors:Aziz, M, Wang, X, Tripathi, A, Bankaitis, V, Chapman, K.D.
Deposit date:2018-05-23
Release date:2019-03-27
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Structural analysis of a plant fatty acid amide hydrolase provides insights into the evolutionary diversity of bioactive acylethanolamides.
J.Biol.Chem., 294, 2019
6DHV
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BU of 6dhv by Molmil
Structure of Arabidopsis Fatty Acid Amide Hydrolase
Descriptor: Fatty acid amide hydrolase
Authors:Aziz, M, Wang, X, Tripathi, A, Bankaitis, V, Chapman, K.D.
Deposit date:2018-05-21
Release date:2019-03-27
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.099 Å)
Cite:Structural analysis of a plant fatty acid amide hydrolase provides insights into the evolutionary diversity of bioactive acylethanolamides.
J.Biol.Chem., 294, 2019
4M8Z
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BU of 4m8z by Molmil
Crystal Structure of SFH3, a phosphatidylinositol transfer protein that integrates phosphoinositide signaling with lipid droplet metabolism
Descriptor: Phosphatidylinositol transfer protein PDR16
Authors:Ortlund, E.O, Pathak, M.C.
Deposit date:2013-08-14
Release date:2014-09-10
Last modified:2019-07-17
Method:X-RAY DIFFRACTION (1.928 Å)
Cite:A phosphatidylinositol transfer protein integrates phosphoinositide signaling with lipid droplet metabolism to regulate a developmental program of nutrient stress-induced membrane biogenesis.
Mol Biol Cell, 25, 2014
7ZGD
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Structure of yeast Sec14p with NPPM244
Descriptor: (4-bromanyl-3-nitro-phenyl)-[4-(2-fluorophenyl)piperazin-1-yl]methanone, SEC14 cytosolic factor
Authors:Hong, Z, Johnen, P, Schaaf, G, Bono, F.
Deposit date:2022-04-03
Release date:2023-01-25
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.08 Å)
Cite:Mechanisms by which small molecules of diverse chemotypes arrest Sec14 lipid transfer activity.
J.Biol.Chem., 299, 2023
7ZGB
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BU of 7zgb by Molmil
Structure of yeast Sec14p with NPPM112
Descriptor: 4-fluoranyl-~{N}-[(4-pyrrolidin-1-ylphenyl)methyl]benzamide, SEC14 cytosolic factor
Authors:Hong, Z, Johnen, P, Schaaf, G, Bono, F.
Deposit date:2022-04-03
Release date:2023-01-25
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Mechanisms by which small molecules of diverse chemotypes arrest Sec14 lipid transfer activity.
J.Biol.Chem., 299, 2023
7ZGC
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BU of 7zgc by Molmil
Structure of yeast Sec14p with NPPM481
Descriptor: (4-chloranyl-3-nitro-phenyl)-[4-(2-fluorophenyl)piperazin-1-yl]methanone, PHOSPHATE ION, SEC14 cytosolic factor
Authors:Hong, Z, Johnen, P, Schaaf, G, Bono, F.
Deposit date:2022-04-03
Release date:2023-01-25
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.236 Å)
Cite:Mechanisms by which small molecules of diverse chemotypes arrest Sec14 lipid transfer activity.
J.Biol.Chem., 299, 2023
7ZG9
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BU of 7zg9 by Molmil
Structure of yeast Sec14p with himbacine
Descriptor: Himbacine, SEC14 cytosolic factor
Authors:Hong, Z, Johnen, P, Schaaf, G, Bono, F.
Deposit date:2022-04-03
Release date:2023-01-25
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (1.764 Å)
Cite:Mechanisms by which small molecules of diverse chemotypes arrest Sec14 lipid transfer activity.
J.Biol.Chem., 299, 2023
7ZGA
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BU of 7zga by Molmil
Structure of yeast Sec14p with ergoline
Descriptor: SEC14 cytosolic factor, ~{O}9-methyl ~{O}4-[2,2,2-tris(chloranyl)ethyl] (5~{a}~{S},6~{a}~{S},9~{R},10~{a}~{S})-7-methyl-3-nitro-5,5~{a},6,6~{a},8,9,10,10~{a}-octahydroindolo[4,3-fg]quinoline-4,9-dicarboxylate
Authors:Hong, Z, Johnen, P, Schaaf, G, Bono, F.
Deposit date:2022-04-03
Release date:2023-01-25
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.302 Å)
Cite:Mechanisms by which small molecules of diverse chemotypes arrest Sec14 lipid transfer activity.
J.Biol.Chem., 299, 2023
3B7Q
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Crystal Structure of Yeast Sec14 Homolog Sfh1 in Complex with Phosphatidylcholine
Descriptor: (4S,7R)-4-HYDROXY-N,N,N-TRIMETHYL-9-OXO-7-[(PALMITOYLOXY)METHYL]-3,5,8-TRIOXA-4-PHOSPHAHEXACOSAN-1-AMINIUM 4-OXIDE, GLYCEROL, PHOSPHATE ION, ...
Authors:Ortlund, E.A, Schaaf, G, Redinbo, M.R, Bankaitis, V.
Deposit date:2007-10-31
Release date:2008-02-19
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.03 Å)
Cite:Functional anatomy of phospholipid binding and regulation of phosphoinositide homeostasis by proteins of the sec14 superfamily
Mol.Cell, 29, 2008
3B74
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BU of 3b74 by Molmil
Crystal Structure of Yeast Sec14 Homolog Sfh1 in Complex with Phosphatidylethanolamine
Descriptor: 1,2-dioleoyl-sn-glycero-3-phosphoethanolamine, Uncharacterized protein YKL091C
Authors:Ortlund, E.A, Schaaf, G, Redinbo, M.R, Bankaitis, V.
Deposit date:2007-10-30
Release date:2008-02-19
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Functional anatomy of phospholipid binding and regulation of phosphoinositide homeostasis by proteins of the sec14 superfamily
Mol.Cell, 29, 2008
3B7N
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BU of 3b7n by Molmil
Crystal Structure of Yeast Sec14 Homolog Sfh1 in Complex with Phosphatidylinositol
Descriptor: (1R)-2-{[(S)-hydroxy{[(1S,2R,3R,4S,5S,6R)-2,3,4,5,6-pentahydroxycyclohexyl]oxy}phosphoryl]oxy}-1-[(octadecanoyloxy)methyl]ethyl (9Z)-octadec-9-enoate, ACETATE ION, PHOSPHATE ION, ...
Authors:Ortlund, E.A, Schaaf, G, Redinbo, M.R, Bankaitis, V.
Deposit date:2007-10-31
Release date:2008-02-19
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (1.86 Å)
Cite:Functional anatomy of phospholipid binding and regulation of phosphoinositide homeostasis by proteins of the sec14 superfamily
Mol.Cell, 29, 2008
3B7Z
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Crystal Structure of Yeast Sec14 Homolog Sfh1 in Complex with Phosphatidylcholine or Phosphatidylinositol
Descriptor: (1R)-2-{[(S)-hydroxy{[(1S,2R,3R,4S,5S,6R)-2,3,4,5,6-pentahydroxycyclohexyl]oxy}phosphoryl]oxy}-1-[(octadecanoyloxy)methyl]ethyl (9Z)-octadec-9-enoate, (4S,7R)-4-HYDROXY-N,N,N-TRIMETHYL-9-OXO-7-[(PALMITOYLOXY)METHYL]-3,5,8-TRIOXA-4-PHOSPHAHEXACOSAN-1-AMINIUM 4-OXIDE, Uncharacterized protein YKL091C
Authors:Ortlund, E.A, Schaaf, G, Redinbo, M.R, Bankaitis, V.
Deposit date:2007-10-31
Release date:2008-02-19
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2.03 Å)
Cite:Functional anatomy of phospholipid binding and regulation of phosphoinositide homeostasis by proteins of the sec14 superfamily
Mol.Cell, 29, 2008
6F0E
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BU of 6f0e by Molmil
Structure of yeast Sec14p with a picolinamide compound
Descriptor: SEC14 cytosolic factor, ~{N}-(1,3-benzodioxol-5-ylmethyl)-5-bromanyl-3-fluoranyl-pyridine-2-carboxamide
Authors:Hong, Z, Johnen, P, Schaaf, G, Bono, F.
Deposit date:2017-11-20
Release date:2018-01-17
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Target Identification and Mechanism of Action of Picolinamide and Benzamide Chemotypes with Antifungal Properties.
Cell Chem Biol, 25, 2018

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