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7LHE
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BU of 7lhe by Molmil
Structure of full-length IP3R1 channel reconstituted into lipid nanodisc in the apo-state
Descriptor: (9R,11S)-9-({[(1S)-1-HYDROXYHEXADECYL]OXY}METHYL)-2,2-DIMETHYL-5,7,10-TRIOXA-2LAMBDA~5~-AZA-6LAMBDA~5~-PHOSPHAOCTACOSANE-6,6,11-TRIOL, Inositol 1,4,5-trisphosphate receptor type 1, ZINC ION
Authors:Baker, M.R, Fan, G, Baker, M.L, Serysheva, I.I.
Deposit date:2021-01-22
Release date:2021-06-02
Last modified:2024-03-06
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:Cryo-EM structure of type 1 IP3R channel in a lipid bilayer
Commun Biol, 4, 2021
7LHF
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BU of 7lhf by Molmil
Structure of full-length IP3R1 channel solubilized in LNMG & lipid in the apo-state
Descriptor: (9R,11S)-9-({[(1S)-1-HYDROXYHEXADECYL]OXY}METHYL)-2,2-DIMETHYL-5,7,10-TRIOXA-2LAMBDA~5~-AZA-6LAMBDA~5~-PHOSPHAOCTACOSANE-6,6,11-TRIOL, Inositol 1,4,5-trisphosphate receptor type 1, ZINC ION
Authors:Baker, M.R, Fan, G, Baker, M.L, Serysheva, I.I.
Deposit date:2021-01-22
Release date:2021-06-02
Last modified:2024-03-06
Method:ELECTRON MICROSCOPY (2.96 Å)
Cite:Cryo-EM structure of type 1 IP3R channel in a lipid bilayer
Commun Biol, 4, 2021
8EAR
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BU of 8ear by Molmil
Structure of the full-length IP3R1 channel determined in the presence of Calcium/IP3/ATP
Descriptor: (9R,11S)-9-({[(1S)-1-HYDROXYHEXADECYL]OXY}METHYL)-2,2-DIMETHYL-5,7,10-TRIOXA-2LAMBDA~5~-AZA-6LAMBDA~5~-PHOSPHAOCTACOSANE-6,6,11-TRIOL, ADENOSINE-5'-TRIPHOSPHATE, CALCIUM ION, ...
Authors:Fan, G, Baker, M.R, Terry, L.E, Arige, V, Chen, M, Seryshev, A.B, Baker, M.L, Ludtke, S.J, Yule, D.I, Serysheva, I.I.
Deposit date:2022-08-29
Release date:2022-11-23
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:Conformational motions and ligand-binding underlying gating and regulation in IP 3 R channel.
Nat Commun, 13, 2022
8EAQ
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BU of 8eaq by Molmil
Structure of the full-length IP3R1 channel determined at high Ca2+
Descriptor: (9R,11S)-9-({[(1S)-1-HYDROXYHEXADECYL]OXY}METHYL)-2,2-DIMETHYL-5,7,10-TRIOXA-2LAMBDA~5~-AZA-6LAMBDA~5~-PHOSPHAOCTACOSANE-6,6,11-TRIOL, CALCIUM ION, Inositol 1,4,5-trisphosphate receptor type 1, ...
Authors:Fan, G, Baker, M.R, Terry, L.E, Arige, V, Chen, M, Seryshev, A.B, Baker, M.L, Ludtke, S.J, Yule, D.I, Serysheva, I.I.
Deposit date:2022-08-29
Release date:2022-11-23
Method:ELECTRON MICROSCOPY (3.26 Å)
Cite:Conformational motions and ligand-binding underlying gating and regulation in IP 3 R channel.
Nat Commun, 13, 2022
6MU2
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BU of 6mu2 by Molmil
Structure of full-length IP3R1 channel in the Apo-state
Descriptor: Inositol 1,4,5-trisphosphate receptor type 1
Authors:Serysheva, I.I, Fan, G, Baker, M.R, Wang, Z, Seryshev, A, Ludtke, S.J, Baker, M.L.
Deposit date:2018-10-22
Release date:2018-12-05
Last modified:2019-11-27
Method:ELECTRON MICROSCOPY (3.9 Å)
Cite:Cryo-EM reveals ligand induced allostery underlying InsP3R channel gating.
Cell Res., 28, 2018
6MU1
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BU of 6mu1 by Molmil
Structure of full-length IP3R1 channel bound with Adenophostin A
Descriptor: Adenophostin A, Inositol 1,4,5-trisphosphate receptor type 1
Authors:Serysheva, I.I, Fan, G, Baker, M.R, Wang, Z, Seryshev, A, Ludtke, S.J, Baker, M.L.
Deposit date:2018-10-22
Release date:2018-12-05
Last modified:2019-11-27
Method:ELECTRON MICROSCOPY (4.1 Å)
Cite:Cryo-EM reveals ligand induced allostery underlying InsP3R channel gating.
Cell Res., 28, 2018
3JAV
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BU of 3jav by Molmil
Structure of full-length IP3R1 channel in the apo-state determined by single particle cryo-EM
Descriptor: Inositol 1,4,5-trisphosphate receptor type 1
Authors:Fan, G, Baker, M.L, Wang, Z, Baker, M.R, Sinyagovskiy, P.A, Chiu, W, Ludtke, S.J, Serysheva, I.I.
Deposit date:2015-06-30
Release date:2015-10-07
Last modified:2024-02-21
Method:ELECTRON MICROSCOPY (4.7 Å)
Cite:Gating machinery of InsP3R channels revealed by electron cryomicroscopy.
Nature, 527, 2015
3G43
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BU of 3g43 by Molmil
Crystal structure of the calmodulin-bound Cav1.2 C-terminal regulatory domain dimer
Descriptor: CALCIUM ION, Calmodulin, Voltage-dependent L-type calcium channel subunit alpha-1C
Authors:Fallon, J.L, Quiocho, F.A.
Deposit date:2009-02-03
Release date:2009-03-03
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Crystal structure of dimeric cardiac L-type calcium channel regulatory domains bridged by Ca2+{middle dot}calmodulins.
Proc.Natl.Acad.Sci.USA, 106, 2009

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