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2W40
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CRYSTAL STRUCTURE OF PLASMODIUM FALCIPARUM GLYCEROL KINASE WITH BOUND GLYCEROL
Descriptor:GLYCEROL KINASE, PUTATIVE, 1,2-ETHANEDIOL, ...
Authors:Schnick, C., Polley, S.D., Fivelman, Q.L., Ranford-Cartwright, L., Wilkinson, S.R., Brannigan, J.A., Wilkinson, A.J., Baker, D.A.
Deposit date:2008-11-18
Release date:2008-12-02
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.49 Å)
Cite:Structure and Non-Essential Function of Glycerol Kinase in Plasmodium Falciparum Blood Stages.
Mol.Microbiol., 71, 2009
2W41
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CRYSTAL STRUCTURE OF PLASMODIUM FALCIPARUM GLYCEROL KINASE WITH ADP
Descriptor:GLYCEROL KINASE, PUTATIVE, ADENOSINE-5'-DIPHOSPHATE, ...
Authors:Schnick, C., Polley, S.D., Fivelman, Q.L., Ranford-Cartwright, L., Wilkinson, S.R., Brannigan, J.A., Wilkinson, A.J., Baker, D.A.
Deposit date:2008-11-18
Release date:2008-12-02
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.41 Å)
Cite:Structure and Non-Essential Function of Glycerol Kinase in Plasmodium Falciparum Blood Stages.
Mol.Microbiol., 71, 2009
5DYK
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CRYSTAL STRUCTURE OF THE CGMP-DEPENDENT PROTEIN KINASE PKG FROM PLASMODIUM FALCIPARUM - APO FORM
Descriptor:CGMP-dependent protein kinase, 1,2-ETHANEDIOL, SULFATE ION, ...
Authors:Wernimont, A.K., Tempel, W., He, H., Seitova, A., Hills, T., Neculai, A.M., Baker, D.A., Flueck, C., Kettleborough, C.A., Arrowsmith, C.H., Edwards, A.M., Bountra, C., Hui, R., Hutchinson, A., El Bakkouri, M., Structural Genomics Consortium (SGC)
Deposit date:2015-09-24
Release date:2015-11-04
Last modified:2019-07-03
Method:X-RAY DIFFRACTION (2.45 Å)
Cite:Structures of the cGMP-dependent protein kinase in malaria parasites reveal a unique structural relay mechanism for activation
Proc.Natl.Acad.Sci.USA, 2019
5DYL
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CRYSTAL STRUCTURE OF THE CGMP-DEPENDENT PROTEIN KINASE PKG FROM PLASMODIUM VIVAX - APO FORM
Descriptor:cGMP-dependent protein kinase, putative
Authors:Wernimont, A.K., Tempel, W., He, H., Seitova, A., Hills, T., Neculai, A.M., Baker, D.A., Flueck, C., Kettleborough, C.A., Arrowsmith, C.H., Edwards, A.M., Bountra, C., Hui, R., Hutchinson, A., El Bakkouri, M., Structural Genomics Consortium (SGC)
Deposit date:2015-09-24
Release date:2015-11-04
Last modified:2019-07-03
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Structures of the cGMP-dependent protein kinase in malaria parasites reveal a unique structural relay mechanism for activation
Proc.Natl.Acad.Sci.USA, 2019
5EZR
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CRYSTAL STRUCTURE OF PVX_084705 BOUND TO COMPOUND
Descriptor:cGMP-dependent protein kinase, putative, N-[5-(3-{2-[(cyclopropylmethyl)amino]pyrimidin-4-yl}-7-[(dimethylamino)methyl]-6-methylimidazo[1,2-a]pyridin-2-yl)-2-fluorophenyl]methanesulfonamide, ...
Authors:El Bakkouri, M., Amani, M., Walker, J.R., Osborne, S., Large, J.M., Birchall, K., Bouloc, N., Smiljanic-Hurley, E., Wheldon, M., Harding, D.J., Merritt, A.T., Ansell, K.H., Coombs, P.J., Kettleborough, C.A., Stewart, B.L., Bowyer, P.W., Gutteridge, W.E., Arrowsmith, C.H., Edwards, A.M., Bountra, C., Baker, D.A., Hui, R., Loppnau, P., Structural Genomics Consortium (SGC)
Deposit date:2015-11-26
Release date:2017-05-10
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Crystal Structure of PVX_084705 bound to compound
To Be Published
5FET
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CRYSTAL STRUCTURE OF PVX_084705 IN PRESENCE OF COMPOUND 2
Descriptor:cGMP-dependent protein kinase, putative, 4-[7-[(dimethylamino)methyl]-2-(4-fluorophenyl)imidazo[1,2-a]pyridin-3-yl]pyrimidin-2-amine
Authors:Wernimont, A.K., Tempel, W., Walker, J.R., He, H., Seitova, A., Hills, T., Neculai, A.M., Baker, D.A., Flueck, C., Kettleborough, C.A., Arrowsmith, C.H., Edwards, A.M., Bountra, C., Hui, R., Hutchinson, A., El Bakkouri, M., Structural Genomics Consortium (SGC)
Deposit date:2015-12-17
Release date:2016-01-13
Last modified:2017-11-22
Method:X-RAY DIFFRACTION (3.07 Å)
Cite:Crystal Structure of PVX_084705 in presence of Compound 2
To be published
4OFF
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CRYSTAL STRUCTURE OF APO CARBOXY CGMP BINDING DOMAIN OF PLASMODIUM FALCIPARUM PKG
Descriptor:CGMP-dependent protein kinase, SULFATE ION
Authors:Kim, J.J., Sanabria figueroa, E., Kim, C.
Deposit date:2014-01-14
Release date:2015-01-21
Last modified:2015-02-11
Method:X-RAY DIFFRACTION (1.888 Å)
Cite:Crystal Structures of the Carboxyl cGMP Binding Domain of the Plasmodium falciparum cGMP-dependent Protein Kinase Reveal a Novel Capping Triad Crucial for Merozoite Egress.
Plos Pathog., 11, 2015
4OFG
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CO-CRYSTAL STRUCTURE OF CARBOXY CGMP BINDING DOMAIN OF PLASMODIUM FALCIPARUM PKG WITH CGMP
Descriptor:CGMP-dependent protein kinase, CYCLIC GUANOSINE MONOPHOSPHATE, PENTANE-1,5-DIAMINE, ...
Authors:Kim, J.J., Sanabria figueroa, E., Kim, C.
Deposit date:2014-01-14
Release date:2015-01-21
Last modified:2015-02-11
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystal Structures of the Carboxyl cGMP Binding Domain of the Plasmodium falciparum cGMP-dependent Protein Kinase Reveal a Novel Capping Triad Crucial for Merozoite Egress.
Plos Pathog., 11, 2015
5DZC
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CRYSTAL STRUCTURE OF THE CGMP-DEPENDENT PROTEIN KINASE PKG FROM PLASMODIUM VIVAX - AMPPNP BOUND
Descriptor:cGMP-dependent protein kinase, putative, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, ...
Authors:Walker, J.R., El Bakkouri, M., Loppnau, P., Graslund, S., He, H., Seitova, A., Hutchinson, A., Bountra, C., Edwards, A.M., Arrowsmith, C.H., Hui, R., Amani, M., Structural Genomics Consortium (SGC)
Deposit date:2015-09-25
Release date:2015-10-14
Last modified:2019-07-03
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structures of the cGMP-dependent protein kinase in malaria parasites reveal a unique structural relay mechanism for activation
Proc.Natl.Acad.Sci.USA, 2019
5E16
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CO-CRYSTAL STRUCTURE OF THE N-TERMIAL CGMP BINDING DOMAIN OF PLASMODIUM FALCIPARUM PKG WITH CGMP
Descriptor:CGMP-dependent protein kinase, CYCLIC GUANOSINE MONOPHOSPHATE
Authors:El Bakkouri, M., Walker, J.R., Loppnau, P., Arrowsmith, C.H., Edwards, A.M., Bountra, C., Hui, R., Structural Genomics Consortium (SGC)
Deposit date:2015-09-29
Release date:2015-11-04
Last modified:2019-07-03
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:Structures of the cGMP-dependent protein kinase in malaria parasites reveal a unique structural relay mechanism for activation
Proc.Natl.Acad.Sci.USA, 2019