Author results

5FN2
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CRYO-EM STRUCTURE OF GAMMA SECRETASE IN COMPLEX WITH A DRUG DAPT
Descriptor:NICASTRIN, PRESENILIN-1, GAMMA-SECRETASE SUBUNIT APH-1A, ...
Authors:Bai, X.C., Rajendra, E., Yang, G.H., Shi, Y.G., Scheres, S.H.W.
Deposit date:2015-11-10
Release date:2015-12-16
Last modified:2016-12-21
Method:ELECTRON MICROSCOPY (4.2 Å)
Cite:Sampling the conformational space of the catalytic subunit of human gamma-secretase.
Elife, 4, 2015
5FN3
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CRYO-EM STRUCTURE OF GAMMA SECRETASE IN CLASS 1 OF THE APO- STATE ENSEMBLE
Descriptor:NICASTRIN, PRESENILIN-1, GAMMA-SECRETASE SUBUNIT APH-1A, ...
Authors:Bai, X.C., Rajendra, E., Yang, G.H., Shi, Y.G., Scheres, S.H.W.
Deposit date:2015-11-10
Release date:2015-12-16
Last modified:2016-12-21
Method:ELECTRON MICROSCOPY (4.1 Å)
Cite:Sampling the conformational space of the catalytic subunit of human gamma-secretase.
Elife, 4, 2015
5FN4
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CRYO-EM STRUCTURE OF GAMMA SECRETASE IN CLASS 2 OF THE APO- STATE ENSEMBLE
Descriptor:NICASTRIN, PRESENILIN-1, GAMMA-SECRETASE SUBUNIT APH-1A, ...
Authors:Bai, X.C., Rajendra, E., Yang, G.H., Shi, Y.G., Scheres, S.H.W.
Deposit date:2015-11-10
Release date:2015-12-16
Last modified:2016-12-21
Method:ELECTRON MICROSCOPY (4 Å)
Cite:Sampling the conformational space of the catalytic subunit of human gamma-secretase.
Elife, 4, 2015
5FN5
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CRYO-EM STRUCTURE OF GAMMA SECRETASE IN CLASS 3 OF THE APO- STATE ENSEMBLE
Descriptor:NICASTRIN, PRESENILIN-1, GAMMA-SECRETASE SUBUNIT APH-1A, ...
Authors:Bai, X.C., Rajendra, E., Yang, G.H., Shi, Y.G., Scheres, S.H.W.
Deposit date:2015-11-10
Release date:2015-12-16
Last modified:2016-12-21
Method:ELECTRON MICROSCOPY (4.3 Å)
Cite:Sampling the conformational space of the catalytic subunit of human gamma-secretase.
Elife, 4, 2015
5GKY
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STRUCTURE OF RYR1 IN A CLOSED STATE (C1 CONFORMER)
Descriptor:Ryanodine receptor 1, Peptidyl-prolyl cis-trans isomerase FKBP1A, ZINC ION
Authors:Bai, X.C., Yan, Z., Wu, J.P., Yan, N.
Deposit date:2016-07-07
Release date:2016-08-24
Last modified:2016-09-21
Method:ELECTRON MICROSCOPY (3.8 Å)
Cite:The Central domain of RyR1 is the transducer for long-range allosteric gating of channel opening
Cell Res., 26, 2016
5GKZ
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STRUCTURE OF RYR1 IN A CLOSED STATE (C3 CONFORMER)
Descriptor:Ryanodine receptor 1, Peptidyl-prolyl cis-trans isomerase FKBP1A, ZINC ION
Authors:Bai, X.C., Yan, Z., Wu, J.P., Yan, N.
Deposit date:2016-07-07
Release date:2016-08-24
Last modified:2016-09-21
Method:ELECTRON MICROSCOPY (4 Å)
Cite:The Central domain of RyR1 is the transducer for long-range allosteric gating of channel opening
Cell Res., 26, 2016
5GL0
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STRUCTURE OF RYR1 IN A CLOSED STATE (C4 CONFORMER)
Descriptor:Ryanodine receptor 1, Peptidyl-prolyl cis-trans isomerase FKBP1A, ZINC ION
Authors:Bai, X.C., Yan, Z., Wu, J.P., Yan, N.
Deposit date:2016-07-07
Release date:2016-08-24
Last modified:2016-09-21
Method:ELECTRON MICROSCOPY (4.2 Å)
Cite:The Central domain of RyR1 is the transducer for long-range allosteric gating of channel opening
Cell Res., 26, 2016
5GL1
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STRUCTURE OF RYR1 IN AN OPEN STATE
Descriptor:Ryanodine receptor 1, Peptidyl-prolyl cis-trans isomerase FKBP1A, ZINC ION
Authors:Bai, X.C., Yan, Z., Wu, J.P., Yan, N.
Deposit date:2016-07-07
Release date:2016-08-24
Last modified:2016-09-21
Method:ELECTRON MICROSCOPY (5.7 Å)
Cite:The Central domain of RyR1 is the transducer for long-range allosteric gating of channel opening
Cell Res., 26, 2016
5GAM
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FOOT REGION OF THE YEAST SPLICEOSOMAL U4/U6.U5 TRI-SNRNP
Descriptor:U5 snRNA, Pre-mRNA-splicing factor 8, Pre-mRNA-splicing factor SNU114, ...
Authors:Nguyen, T.H.D., Galej, W.P., Bai, X.C., Oubridge, C., Scheres, S.H.W., Newman, A.J., Nagai, K.
Deposit date:2015-12-15
Release date:2016-02-03
Last modified:2017-08-30
Method:ELECTRON MICROSCOPY (3.7 Å)
Cite:Cryo-EM structure of the yeast U4/U6.U5 tri-snRNP at 3.7 Angstrom resolution
Nature, 530, 2016
5GAN
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THE OVERALL STRUCTURE OF THE YEAST SPLICEOSOMAL U4/U6.U5 TRI-SNRNP AT 3.7 ANGSTROM
Descriptor:U4 snRNA, U6 snRNA, Pre-mRNA-splicing factor 8, ...
Authors:Nguyen, T.H.D., Galej, W.P., Bai, X.C., Oubridge, C., Scheres, S.H.W., Newman, A.J., Nagai, K.
Deposit date:2015-12-15
Release date:2016-01-27
Last modified:2019-02-20
Method:ELECTRON MICROSCOPY (3.6 Å)
Cite:Cryo-EM structure of the yeast U4/U6.U5 tri-snRNP at 3.7 angstrom resolution.
Nature, 530, 2016
5GAO
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HEAD REGION OF THE YEAST SPLICEOSOMAL U4/U6.U5 TRI-SNRNP
Descriptor:Small nuclear ribonucleoprotein-associated protein B, Small nuclear ribonucleoprotein Sm D1, Small nuclear ribonucleoprotein Sm D2, ...
Authors:Nguyen, T.H.D., Galej, W.P., Bai, X.C., Oubridge, C., Scheres, S.H.W., Newman, A.J., Nagai, K.
Deposit date:2015-12-15
Release date:2016-01-27
Last modified:2018-10-03
Method:ELECTRON MICROSCOPY (3.6 Å)
Cite:Cryo-EM structure of the yeast U4/U6.U5 tri-snRNP at 3.7 angstrom resolution.
Nature, 530, 2016
3J6B
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STRUCTURE OF THE YEAST MITOCHONDRIAL LARGE RIBOSOMAL SUBUNIT
Descriptor:21S ribosomal RNA, 54S ribosomal protein RML2, mitochondrial, ...
Authors:Amunts, A., Brown, A., Bai, X.C., Llacer, J.L., Hussain, T., Emsley, P., Long, F., Murshudov, G., Scheres, S.H.W., Ramakrishnan, V.
Deposit date:2014-01-22
Release date:2014-04-09
Last modified:2018-07-18
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:Structure of the yeast mitochondrial large ribosomal subunit.
Science, 343, 2014
3J79
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CRYO-EM STRUCTURE OF THE PLASMODIUM FALCIPARUM 80S RIBOSOME BOUND TO THE ANTI-PROTOZOAN DRUG EMETINE, LARGE SUBUNIT
Descriptor:28S ribosomal RNA, 5S ribosomal RNA, 5.8S ribosomal RNA, ...
Authors:Wong, W., Bai, X.C., Brown, A., Fernandez, I.S., Hanssen, E., Condron, M., Tan, Y.H., Baum, J., Scheres, S.H.W.
Deposit date:2014-06-02
Release date:2014-07-16
Last modified:2018-07-18
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:Cryo-EM structure of the Plasmodium falciparum 80S ribosome bound to the anti-protozoan drug emetine.
Elife, 3, 2014
3J7A
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CRYO-EM STRUCTURE OF THE PLASMODIUM FALCIPARUM 80S RIBOSOME BOUND TO THE ANTI-PROTOZOAN DRUG EMETINE, SMALL SUBUNIT
Descriptor:18S ribosomal RNA, 40S ribosomal protein eS1, 40S ribosomal protein uS2, ...
Authors:Wong, W., Bai, X.C., Brown, A., Fernandez, I.S., Hanssen, E., Condron, M., Tan, Y.H., Baum, J., Scheres, S.H.W.
Deposit date:2014-06-03
Release date:2014-07-16
Last modified:2018-07-18
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:Cryo-EM structure of the Plasmodium falciparum 80S ribosome bound to the anti-protozoan drug emetine.
Elife, 3, 2014
3J7Y
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STRUCTURE OF THE LARGE RIBOSOMAL SUBUNIT FROM HUMAN MITOCHONDRIA
Descriptor:16S rRNA, mt-tRNAVal, uL2, ...
Authors:Brown, A., Amunts, A., Bai, X.C., Sugimoto, Y., Edwards, P.C., Murshudov, G., Scheres, S.H.W., Ramakrishnan, V.
Deposit date:2014-08-26
Release date:2014-10-15
Last modified:2018-07-18
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:Structure of the large ribosomal subunit from human mitochondria.
Science, 346, 2014
4V8Y
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CRYO-EM RECONSTRUCTION OF THE 80S-EIF5B-MET-ITRNAMET EUKARYOTIC TRANSLATION INITIATION COMPLEX
Descriptor:40S RIBOSOMAL PROTEIN S26-A, 40S RIBOSOMAL PROTEIN S27-A, 40S RIBOSOMAL PROTEIN S28-A, ...
Authors:Fernandez, I.S., Bai, X.C., Hussain, T., Kelley, A.C., Lorsch, J.R., Ramakrishnan, V., Scheres, S.H.W.
Deposit date:2013-07-20
Release date:2014-07-09
Last modified:2018-04-18
Method:ELECTRON MICROSCOPY (4.3 Å)
Cite:Molecular architecture of a eukaryotic translational initiation complex.
Science, 342, 2013
4V8Z
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CRYO-EM RECONSTRUCTION OF THE 80S-EIF5B-MET-ITRNAMET EUKARYOTIC TRANSLATION INITIATION COMPLEX
Descriptor:40S RIBOSOMAL PROTEIN S26-A, 40S RIBOSOMAL PROTEIN S27-A, 40S RIBOSOMAL PROTEIN S28-A, ...
Authors:Fernandez, I.S., Bai, X.C., Hussain, T., Kelley, A.C., Lorsch, J.R., Ramakrishnan, V., Scheres, S.H.W.
Deposit date:2013-07-20
Release date:2014-07-09
Last modified:2018-04-18
Method:ELECTRON MICROSCOPY (6.6 Å)
Cite:Molecular architecture of a eukaryotic translational initiation complex.
Science, 342, 2013
5G5P
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STRUCTURE OF THE SACCHAROMYCES CEREVISIAE TREX-2 COMPLEX
Descriptor:NUCLEAR MRNA EXPORT PROTEIN SAC3, NUCLEAR MRNA EXPORT PROTEIN THP1, 26S PROTEASOME COMPLEX SUBUNIT SEM1
Authors:Aibara, S., Bai, X.C., Stewart, M.
Deposit date:2016-05-26
Release date:2016-11-23
Last modified:2018-07-18
Method:ELECTRON MICROSCOPY (5.3 Å)
Cite:The Sac3 Tpr-Like Region in the Saccharomyces Cerevisiae Trex-2 Complex is More Extensive But Independent of the Cid Region
J.Struct.Biol., 195, 2016
5GAP
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BODY REGION OF THE U4/U6.U5 TRI-SNRNP
Descriptor:U4 snRNA, 5' region, nucleotides 1-67, ...
Authors:Nguyen, T.H.D., Galej, W.P., Oubridge, C., Bai, X.C., Newman, A., Scheres, S., Nagai, K.
Deposit date:2015-12-15
Release date:2016-01-27
Last modified:2017-08-30
Method:ELECTRON MICROSCOPY (3.6 Å)
Cite:Cryo-EM structure of the yeast U4/U6.U5 tri-snRNP at 3.7 angstrom resolution.
Nature, 530, 2016
5MZ6
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CRYO-EM STRUCTURE OF A SEPARASE-SECURIN COMPLEX FROM CAENORHABDITIS ELEGANS AT 3.8 A RESOLUTION
Descriptor:SEParase, Interactor of FizzY protein
Authors:Boland, A., Martin, T.G., Zhang, Z., Yang, J., Bai, X.C., Chang, L., Scheres, S.H.W., Barford, D.
Deposit date:2017-01-31
Release date:2017-03-08
Last modified:2017-08-30
Method:ELECTRON MICROSCOPY (3.8 Å)
Cite:Cryo-EM structure of a metazoan separase-securin complex at near-atomic resolution.
Nat. Struct. Mol. Biol., 24, 2017
5OOL
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STRUCTURE OF A NATIVE ASSEMBLY INTERMEDIATE OF THE HUMAN MITOCHONDRIAL RIBOSOME WITH UNFOLDED INTERFACIAL RRNA
Descriptor:16S ribosomal RNA, mitochondrial tRNAVal, 39S ribosomal protein L2, ...
Authors:Brown, A., Rathore, S., Kimanius, D., Aibara, S., Bai, X.C., Rorbach, J., Amunts, A., Ramakrishnan, V.
Deposit date:2017-08-08
Release date:2017-09-13
Last modified:2019-02-20
Method:ELECTRON MICROSCOPY (3.06 Å)
Cite:Structures of the human mitochondrial ribosome in native states of assembly.
Nat. Struct. Mol. Biol., 24, 2017
5OOM
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STRUCTURE OF A NATIVE ASSEMBLY INTERMEDIATE OF THE HUMAN MITOCHONDRIAL RIBOSOME WITH UNFOLDED INTERFACIAL RRNA
Descriptor:16S ribosomal RNA, mitochondrial tRNAVal, 39S ribosomal protein L2, ...
Authors:Brown, A., Rathore, S., Kimanius, D., Aibara, S., Bai, X.C., Rorbach, J., Amunts, A., Ramakrishnan, V.
Deposit date:2017-08-08
Release date:2017-09-13
Last modified:2018-01-31
Method:ELECTRON MICROSCOPY (3.03 Å)
Cite:Structures of the human mitochondrial ribosome in native states of assembly.
Nat. Struct. Mol. Biol., 24, 2017
6D7W
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CRYO-EM STRUCTURE OF THE MITOCHONDRIAL CALCIUM UNIPORTER FROM N. FISCHERI AT 3.8 ANGSTROM RESOLUTION
Descriptor:Mitochondrial calcium uniporter, CALCIUM ION
Authors:Nguyen, N.X., Armache, J.P., Cheng, Y., Bai, X.C.
Deposit date:2018-04-25
Release date:2018-07-11
Last modified:2018-08-01
Method:ELECTRON MICROSCOPY (3.8 Å)
Cite:Cryo-EM structure of a fungal mitochondrial calcium uniporter.
Nature, 559, 2018
6D80
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CRYO-EM STRUCTURE OF THE MITOCHONDRIAL CALCIUM UNIPORTER FROM N. FISCHERI BOUND TO SAPOSIN
Descriptor:Saposin A, Mitochondrial calcium uniporter, CALCIUM ION
Authors:Nguyen, N.X., Armache, J.P., Cheng, Y., Bai, X.C.
Deposit date:2018-04-25
Release date:2018-07-11
Last modified:2018-08-01
Method:ELECTRON MICROSCOPY (5 Å)
Cite:Cryo-EM structure of a fungal mitochondrial calcium uniporter.
Nature, 559, 2018
4V5X
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THE CRYO-EM STRUCTURE OF A 3D DNA-ORIGAMI OBJECT
Descriptor:SCAFFOLD STRAND, STAPLE STRAND
Authors:Bai, X.C., Martin, T.G., Scheres, S.H.W., Dietz, H.
Deposit date:2012-10-09
Release date:2014-07-09
Last modified:2017-08-02
Method:ELECTRON MICROSCOPY (11.5 Å)
Cite:Cryo-Em Structure of a 3D DNA-Origami Object.
Proc.Natl.Acad.Sci.USA, 109, 2012
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