Author results

1RRX
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CRYSTALLOGRAPHIC EVIDENCE FOR ISOMERIC CHROMOPHORES IN 3-FLUOROTYROSYL-GREEN FLUORESCENT PROTEIN
Descriptor:SIGF1-GFP fusion protein
Authors:Bae, J.H., Paramita Pal, P., Moroder, L., Huber, R., Budisa, N.
Deposit date:2003-12-09
Release date:2004-06-08
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Crystallographic Evidence for Isomeric Chromophores in 3-Fluorotyrosyl-Green Fluorescent Protein.
Chembiochem, 5, 2004
3GQI
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CRYSTAL STRUCTURE OF ACTIVATED RECEPTOR TYROSINE KINASE IN COMPLEX WITH SUBSTRATES
Descriptor:Basic fibroblast growth factor receptor 1, Phospholipase C-gamma-1, DECAVANADATE, ...
Authors:Bae, J.H., Lew, E.D., Yuzawa, S., Tome, F., Lax, I., Schlessinger, J.
Deposit date:2009-03-24
Release date:2009-08-18
Last modified:2017-11-01
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:The selectivity of receptor tyrosine kinase signaling is controlled by a secondary SH2 domain binding site.
Cell(Cambridge,Mass.), 138, 2009
3GQL
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CRYSTAL STRUCTURE OF ACTIVATED RECEPTOR TYROSINE KINASE IN COMPLEX WITH SUBSTRATES
Descriptor:Basic fibroblast growth factor receptor 1, (E)-[4-(3,5-difluorophenyl)-3H-pyrrolo[2,3-b]pyridin-3-ylidene](3-methoxyphenyl)methanol
Authors:Bae, J.H., Lew, E.D., Yuzawa, S., Tome, F., Lax, I., Schlessinger, J.
Deposit date:2009-03-24
Release date:2009-08-18
Last modified:2017-11-01
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:The selectivity of receptor tyrosine kinase signaling is controlled by a secondary SH2 domain binding site.
Cell(Cambridge,Mass.), 138, 2009
3KXX
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STRUCTURE OF THE MUTANT FIBROBLAST GROWTH FACTOR RECEPTOR 1
Descriptor:Basic fibroblast growth factor receptor 1
Authors:Bae, J.H., Boggon, T.J., Tome, F., Mandiyan, V., Lax, I., Schlessinger, J.
Deposit date:2009-12-04
Release date:2010-03-02
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Asymmetric receptor contact is required for tyrosine autophosphorylation of fibroblast growth factor receptor in living cells.
Proc.Natl.Acad.Sci.USA, 107, 2010
3KY2
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CRYSTAL STRUCTURE OF FIBROBLAST GROWTH FACTOR RECEPTOR 1 KINASE DOMAIN
Descriptor:Basic fibroblast growth factor receptor 1, SULFATE ION
Authors:Bae, J.H., Boggon, T.J., Tome, F., Mandiyan, V., Lax, I., Schlessinger, J.
Deposit date:2009-12-04
Release date:2010-03-02
Last modified:2018-03-07
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Asymmetric receptor contact is required for tyrosine autophosphorylation of fibroblast growth factor receptor in living cells.
Proc.Natl.Acad.Sci.USA, 107, 2010
3JS2
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CRYSTAL STRUCTURE OF MINIMAL KINASE DOMAIN OF FIBROBLAST GROWTH FACTOR RECEPTOR 1 IN COMPLEX WITH 5-(2-THIENYL)NICOTINIC ACID
Descriptor:Basic fibroblast growth factor receptor 1, 5-(2-thienyl)nicotinic acid, PHOSPHATE ION
Authors:Bae, J.H., Ravindranathan, K.P., Mandiyan, V., Ekkati, A.R., Schlessinger, J., Jorgensen, W.L.
Deposit date:2009-09-09
Release date:2010-02-23
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Discovery of novel fibroblast growth factor receptor 1 kinase inhibitors by structure-based virtual screening
J.Med.Chem., 53, 2010
1RM9
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PROBING THE ROLE OF TRYPTOPHANS IN AEQUOREA VICTORIA GREEN FLUORESCENT PROTEINS WITH AN EXPANDED GENETIC CODE
Descriptor:avermectin-sensitive chloride channel GluCl beta/cyan fluorescent protein fusion
Authors:Budisa, N., Pal, P.P., Alefelder, S., Birle, P., Krywcun, T., Rubini, M., Wenger, W., Bae, J.H., Steiner, T.
Deposit date:2003-11-27
Release date:2004-06-08
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Probing the role of tryptophans in Aequorea victoria green fluorescent proteins with an expanded genetic code
Biol.Chem., 385, 2004
1RMM
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PROBING THE ROLE OF TRYPTOPHANS IN AEQUOREA VICTORIA GREEN FLUORESCENT PROTEINS WITH AN EXPANDED GENETIC CODE
Descriptor:SIGF1-GFP fusion protein
Authors:Budisa, N., Pal, P.P., Alefelder, S., Birle, P., Krywcun, T., Rubini, M., Wenger, W., Bae, J.H., Steiner, T.
Deposit date:2003-11-28
Release date:2004-06-08
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Probing the role of tryptophans in Aequorea victoria green fluorescent proteins with an expanded genetic code
Biol.Chem., 385, 2004
1RMO
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PROBING THE ROLE OF TRYPTOPHANS IN AEQUOREA VICTORIA GREEN FLUORESCENT PROTEINS WITH AN EXPANDED GENETIC CODE
Descriptor:wunen-nonfunctional GFP fusion protein
Authors:Budisa, N., Pal, P.P., Alefelder, S., Birle, P., Krywcun, T., Rubini, M., Wenger, W., Bae, J.H., Steiner, T.
Deposit date:2003-11-28
Release date:2004-06-08
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Probing the role of tryptophans in Aequorea victoria green fluorescent proteins with an expanded genetic code
Biol.Chem., 385, 2004
1RMP
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PROBING THE ROLE OF TRYPTOPHANS IN AEQUOREA VICTORIA GREEN FLUORESCENT PROTEINS WITH AN EXPANDED GENETIC CODE
Descriptor:SIGF1-GFP fusion protein
Authors:Budisa, N., Pal, P.P., Alefelder, S., Birle, P., Krywcun, T., Rubini, M., Wenger, W., Bae, J.H., Steiner, T.
Deposit date:2003-11-28
Release date:2004-06-08
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3 Å)
Cite:Probing the role of tryptophans in Aequorea victoria green fluorescent proteins with an expanded genetic code
Biol.Chem., 385, 2004
2Q6P
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THE CHEMICAL CONTROL OF PROTEIN FOLDING: ENGINEERING A SUPERFOLDER GREEN FLUORESCENT PROTEIN
Descriptor:Green fluorescent protein mutant 3
Authors:Steiner, T., Hess, P., Bae, J.H., Wiltschi, B., Moroder, L., Budisa, N.
Deposit date:2007-06-05
Release date:2007-06-19
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Synthetic biology of proteins: tuning GFPs folding and stability with fluoroproline.
Plos One, 3, 2008
3B2T
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STRUCTURE OF PHOSPHOTRANSFERASE
Descriptor:Fibroblast growth factor receptor 2, PHOSPHATE ION, 5'-O-[(S)-hydroxy{[(S)-hydroxy(methyl)phosphoryl]oxy}phosphoryl]adenosine
Authors:Lew, E.D., Bae, J.H., Rohmann, E., Wollnik, B., Schlessinger, J.
Deposit date:2007-10-19
Release date:2008-02-26
Last modified:2017-10-25
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structural basis for reduced FGFR2 activity in LADD syndrome: Implications for FGFR autoinhibition and activation.
Proc.Natl.Acad.Sci.Usa, 104, 2007
5Y7W
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CRYSTAL STRUCTURE OF THE NCO-A1 PAS-B DOMAIN WITH YL-2
Descriptor:Nuclear receptor coactivator 1, YL-2 peptide
Authors:Lee, Y.J., Yoon, H.S., Lee, J.H., Bae, J.H., Song, J.Y., Lim, H.S.
Deposit date:2017-08-18
Release date:2017-11-15
Last modified:2017-11-29
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:Targeted Inhibition of the NCOA1/STAT6 Protein-Protein Interaction
J. Am. Chem. Soc., 139, 2017
5Y7X
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HUMAN PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR (PPAR) DELTA IN COMPLEXED WITH A POTENT AND SELECTIVE AGONIST
Descriptor:Peroxisome proliferator-activated receptor delta, 2-[2-methyl-4-[[4-methyl-2-[4-(trifluoromethyl)phenyl]-1,3-selenazol-5-yl]methylsulfanyl]phenoxy]ethanoic acid, POTASSIUM ION, ...
Authors:Kim, H.L., Chin, J.W., Cho, S.J., Song, J.Y., Yoon, H.S., Bae, J.H.
Deposit date:2017-08-18
Release date:2018-08-01
Method:X-RAY DIFFRACTION (1.699 Å)
Cite:Design, synthesis, and the X-ray co-crystal structure of Highly Potent, Selective, and Orally Bioavailable, Novel Peroxisome Proliferator-Activated Receptor delta Agonists
To Be Published
5YSO
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CRYSTAL STRUCTURE OF ESTROGEN RELATED RECEPTOR-3 (ERR-GAMMA) LIGAND BINDING DOMAIN WITH DN200434
Descriptor:Estrogen-related receptor gamma, 4-[5-oxidanyl-2-phenyl-1-[4-(4-propan-2-ylpiperazin-1-yl)phenyl]pent-1-enyl]phenol
Authors:Cho, S.J., Chin, J.W., Yoon, H.S., Jeon, Y.H., Bae, J.H., Song, J.Y.
Deposit date:2017-11-14
Release date:2018-12-26
Method:X-RAY DIFFRACTION (2.501 Å)
Cite:A novel orally active inverse agonist of estrogen-related receptor gamma (ERRg), DN200434, enhances sodium iodide symporter function in mice with anaplastic thyroid cancer
To Be Published
2WSN
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STRUCTURE OF ENHANCED CYAN FLUORESCENT PROTEIN AT PHYSIOLOGICAL PH
Descriptor:GREEN FLUORESCENT PROTEIN
Authors:Lelimousin, M., Noirclerc-Savoye, M., Lazareno-Saez, C., Paetzold, B., Le Vot, S., Chazal, R., Macheboeuf, P., Field, M.J., Bourgeois, D., Royant, A.
Deposit date:2009-09-08
Release date:2009-09-29
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.37 Å)
Cite:Intrinsic Dynamics in Ecfp and Cerulean Control Fluorescence Quantum Yield.
Biochemistry, 48, 2009