Author results

8PRK
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THE R78K AND D117E ACTIVE SITE VARIANTS OF SACCHAROMYCES CEREVISIAE SOLUBLE INORGANIC PYROPHOSPHATASE: STRUCTURAL STUDIES AND MECHANISTIC IMPLICATIONS
Descriptor:PROTEIN (INORGANIC PYROPHOSPHATASE), MANGANESE (II) ION, PHOSPHATE ION
Authors:Tuominen, V., Heikinheimo, P., Kajander, T., Torkkel, T., Hyytia, T., Kapyla, J., Lahti, R., Cooperman, B.S., Goldman, A.
Deposit date:1998-09-16
Release date:1998-12-23
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:The R78K and D117E active-site variants of Saccharomyces cerevisiae soluble inorganic pyrophosphatase: structural studies and mechanistic implications.
J.Mol.Biol., 284, 1998
1F2I
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COCRYSTAL STRUCTURE OF SELECTED ZINC FINGER DIMER BOUND TO DNA
Descriptor:5'-D(*AP*TP*GP*GP*GP*CP*GP*CP*GP*CP*CP*CP*AP*T)-3', FUSION OF N-TERMINAL 17-MER PEPTIDE EXTENSION TO ZIF12, ZINC ION
Authors:Wang, B.S., Grant, R.A., Pabo, C.O.
Deposit date:2000-05-25
Release date:2001-09-14
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.35 Å)
Cite:Selected peptide extension contacts hydrophobic patch on neighboring zinc finger and mediates dimerization on DNA.
Nat.Struct.Biol., 8, 2001
1FOJ
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BOVINE ENDOTHELIAL NITRIC OXIDE SYNTHASE HEME DOMAIN COMPLEXED WITH 7-NITROINDAZOLE-2-CARBOXAMIDINE (H4B PRESENT)
Descriptor:NITRIC-OXIDE SYNTHASE, CACODYLATE ION, ACETATE ION, ...
Authors:Raman, C.S., Li, H., Martasek, P., Masters, B.S., Poulos, T.L.
Deposit date:2000-08-28
Release date:2001-11-16
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Crystal structure of nitric oxide synthase bound to nitro indazole reveals a novel inactivation mechanism
Biochemistry, 40, 2001
1FOL
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REDUCED BOVINE ENDOTHELIAL NITRIC OXIDE SYNTHASE HEME DOMAIN COMPLEXED WITH L-ARG(H4B-FREE)
Descriptor:NITRIC-OXIDE SYNTHASE, CACODYLATE ION, ACETATE ION, ...
Authors:Raman, C.S., Li, H., Martasek, P., Masters, B.S., Poulos, T.L.
Deposit date:2000-08-28
Release date:2001-07-20
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Crystallographic studies on endothelial nitric oxide synthase complexed with nitric oxide and mechanism-based inhibitors
Biochemistry, 40, 2001
1H9P
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CRYSTAL STRUCTURE OF DIOCLEA GUIANENSIS SEED LECTIN
Descriptor:LECTIN ALPHA CHAIN, CADMIUM ION, MANGANESE (II) ION
Authors:Romero, A., Wah, D.A., Gallego Del sol, F., Cavada, B.S., Ramos, M.V., Grangeiro, T.B., Sampaio, A.H., Calvete, J.J.
Deposit date:2001-03-16
Release date:2001-03-23
Last modified:2014-02-05
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystal Structure of Native and Cd/Cd-Substituted Dioclea Guianensis Seed Lectin. A Novel Manganese-Binding Site and Structural Basis of Dimer-Tetramer Association
J.Mol.Biol., 310, 2001
1H9W
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NATIVE DIOCLEA GUIANENSIS SEED LECTIN
Descriptor:SEED LECTIN, MANGANESE (II) ION, CALCIUM ION
Authors:Romero, A., Wah, D.A., Sol, F.G.D., Cavada, B.S., Ramos, M.V., Grangeiro, T.B., Sampaio, A.H., Calvete, J.J.
Deposit date:2001-03-22
Release date:2001-03-23
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystal Structure of Native and Cd/Cd-Substituted Dioclea Guianensis Seed Lectin. A Novel Manganese-Binding Site and Structural Basis of Dimer-Tetramer Association
J.Mol.Biol., 310, 2001
1HY9
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COCAINE AND AMPHETAMINE REGULATED TRANSCRIPT
Descriptor:COCAINE AND AMPHETAMINE REGULATED TRANSCRIPT PROTEIN
Authors:Ludvigsen, S., Thim, L., Blom, A.M., Wulff, B.S.
Deposit date:2001-01-18
Release date:2001-08-29
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Solution structure of the satiety factor, CART, reveals new functionality of a well-known fold.
Biochemistry, 40, 2001
1L2I
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HUMAN ESTROGEN RECEPTOR ALPHA LIGAND-BINDING DOMAIN IN COMPLEX WITH (R,R)-5,11-CIS-DIETHYL-5,6,11,12-TETRAHYDROCHRYSENE-2,8-DIOL AND A GLUCOCORTICOID RECEPTOR INTERACTING PROTEIN 1 NR BOX II PEPTIDE
Descriptor:ESTROGEN RECEPTOR, GLUCOCORTICOID RECEPTOR-INTERACTING PROTEIN 1, CHLORIDE ION, ...
Authors:Shiau, A.K., Barstad, D., Radek, J.T., Meyers, M.J., Nettles, K.W., Katzenellenbogen, B.S., Katzenellenbogen, J.A., Agard, D.A., Greene, G.L.
Deposit date:2002-02-21
Release date:2002-05-01
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Structural characterization of a subtype-selective ligand reveals a novel mode of estrogen receptor antagonism.
Nat.Struct.Biol., 9, 2002
1L2J
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HUMAN ESTROGEN RECEPTOR BETA LIGAND-BINDING DOMAIN IN COMPLEX WITH (R,R)-5,11-CIS-DIETHYL-5,6,11,12-TETRAHYDROCHRYSENE-2,8-DIOL
Descriptor:ESTROGEN RECEPTOR BETA, (R,R)-5,11-CIS-DIETHYL-5,6,11,12-TETRAHYDROCHRYSENE-2,8-DIOL
Authors:Shiau, A.K., Barstad, D., Radek, J.T., Meyers, M.J., Nettles, K.W., Katzenellenbogen, B.S., Katzenellenbogen, J.A., Agard, D.A., Greene, G.L.
Deposit date:2002-02-21
Release date:2002-05-01
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.95 Å)
Cite:Structural characterization of a subtype-selective ligand reveals a novel mode of estrogen receptor antagonism.
Nat.Struct.Biol., 9, 2002
1WB7
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IRON SUPEROXIDE DISMUTASE (FE-SOD) FROM THE HYPERTHERMOPHILE SULFOLOBUS SOLFATARICUS. CRYSTAL STRUCTURE OF THE Y41F MUTANT.
Descriptor:SUPEROXIDE DISMUTASE [FE], FE (III) ION
Authors:Gogliettino, M.A., Tanfani, F., Scire, A., Ursby, T., Adinolfi, B.S., Cacciamani, T., De Vendittis, E.
Deposit date:2004-10-31
Release date:2004-11-08
Last modified:2018-01-17
Method:X-RAY DIFFRACTION (2.24 Å)
Cite:The Role of Tyr41 and His155 in the Functional Properties of Superoxide Dismutase from the Archaeon Sulfolobus Solfataricus
Biochemistry, 43, 2004
2BR6
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CRYSTAL STRUCTURE OF QUORUM-QUENCHING N-ACYL HOMOSERINE LACTONE LACTONASE
Descriptor:AIIA-LIKE PROTEIN, ZINC ION, GLYCEROL, ...
Authors:Kim, M.H., Choi, W.C., Kang, H.O., Kang, B.S., Kim, K.J., Derewenda, Z.S., Lee, J.K., Oh, T.K., Lee, C.H.
Deposit date:2005-05-03
Release date:2005-12-07
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:The Molecular Structure and Catalytic Mechanism of a Quorum-Quenching N-Acyl-L-Homoserine Lactone Hydrolase.
Proc.Natl.Acad.Sci.USA, 102, 2005
2BTN
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CRYSTAL STRUCTURE AND CATALYTIC MECHANISM OF THE QUORUM-QUENCHING N- ACYL HOMOSERINE LACTONE HYDROLASE
Descriptor:AIIA-LIKE PROTEIN, ZINC ION, GLYCEROL
Authors:Kim, M.H., Choi, W.C., Kang, H.O., Lee, J.S., Kang, B.S., Kim, K.J., Derewenda, Z.S., Oh, T.K., Lee, C.H., Lee, J.K.
Deposit date:2005-06-03
Release date:2005-12-07
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:The Molecular Structure and Catalytic Mechanism of a Quorum-Quenching N-Acyl-L-Homoserine Lactone Hydrolase.
Proc.Natl.Acad.Sci.USA, 102, 2005
5KAY
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STRUCTURE OF SPELTER BOUND TO ZN2+
Descriptor:Spelter, ZINC ION, SODIUM ION
Authors:Guffy, S.L., Der, B.S., Kuhlman, B.
Deposit date:2016-06-02
Release date:2016-08-03
Last modified:2017-09-06
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Probing the minimal determinants of zinc binding with computational protein design.
Protein Eng.Des.Sel., 29, 2016
117E
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THE R78K AND D117E ACTIVE SITE VARIANTS OF SACCHAROMYCES CEREVISIAE SOLUBLE INORGANIC PYROPHOSPHATASE: STRUCTURAL STUDIES AND MECHANISTIC IMPLICATIONS
Descriptor:PROTEIN (INORGANIC PYROPHOSPHATASE), MANGANESE (II) ION, PHOSPHATE ION
Authors:Tuominen, V., Heikinheimo, P., Kajander, T., Torkkel, T., Hyytia, T., Kapyla, J., Lahti, R., Cooperman, B.S., Goldman, A.
Deposit date:1998-09-15
Release date:1998-12-23
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:The R78K and D117E active-site variants of Saccharomyces cerevisiae soluble inorganic pyrophosphatase: structural studies and mechanistic implications.
J.Mol.Biol., 284, 1998
1AFT
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SMALL SUBUNIT C-TERMINAL INHIBITORY PEPTIDE OF MOUSE RIBONUCLEOTIDE REDUCTASE AS BOUND TO THE LARGE SUBUNIT, NMR, 26 STRUCTURES
Descriptor:RIBONUCLEOSIDE-DIPHOSPHATE REDUCTASE
Authors:Laub, P.B., Fisher, A.L., Furst, G.T., Barwis, B.A., Hamann, C.S., Cooperman, B.S.
Deposit date:1997-03-13
Release date:1997-05-15
Last modified:2017-11-29
Method:SOLUTION NMR
Cite:NMR structure of an inhibitory R2 C-terminal peptide bound to mouse ribonucleotide reductase R1 subunit.
Nat.Struct.Biol., 2, 1995
1AIS
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TATA-BINDING PROTEIN/TRANSCRIPTION FACTOR (II)B/TATA-BOX COMPLEX FROM PYROCOCCUS WOESEI
Descriptor:DNA (5'-D(*AP*AP*CP*TP*TP*AP*CP*TP*TP*TP*(5IU)P*(5IU)P*AP*AP*AP*GP*C)-3'), DNA (5'-D(*GP*CP*TP*TP*TP*AP*AP*AP*AP*AP*GP*TP*AP*AP*GP*TP*T )-3'), PROTEIN (TATA-BINDING PROTEIN), ...
Authors:Kosa, P.F., Ghosh, G., Dedecker, B.S., Sigler, P.B.
Deposit date:1997-04-24
Release date:1997-07-07
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:The 2.1-A crystal structure of an archaeal preinitiation complex: TATA-box-binding protein/transcription factor (II)B core/TATA-box.
Proc.Natl.Acad.Sci.USA, 94, 1997
1AZD
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CONCANAVALIN FROM CANAVALIA BRASILIENSIS
Descriptor:CONBR, CALCIUM ION, MANGANESE (II) ION
Authors:Sanz-Aparicio, J., Hermoso, J., Grangeiro, T.B., Calvete, J.J., Cavada, B.S.
Deposit date:1997-11-16
Release date:1998-04-29
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3 Å)
Cite:The crystal structure of Canavalia brasiliensis lectin suggests a correlation between its quaternary conformation and its distinct biological properties from Concanavalin A.
FEBS Lett., 405, 1997
1AZP
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HYPERTHERMOPHILE CHROMOSOMAL PROTEIN SAC7D BOUND WITH KINKED DNA DUPLEX
Descriptor:DNA (5'-D(*GP*CP*GP*AP*TP*CP*GP*C)-3'), PROTEIN (HYPERTHERMOPHILE CHROMOSOMAL PROTEIN SAC7D)
Authors:Robinson, H., Gao, Y.-G., Mccrary, B.S., Edmondson, S.P., Shriver, J.W., Wang, A.H.-J.
Deposit date:1997-11-19
Release date:1999-01-13
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:The hyperthermophile chromosomal protein Sac7d sharply kinks DNA.
Nature, 392, 1998
1AZQ
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HYPERTHERMOPHILE CHROMOSOMAL PROTEIN SAC7D BOUND WITH KINKED DNA DUPLEX
Descriptor:DNA (5'-D(*GP*TP*AP*AP*TP*TP*AP*C)-3'), PROTEIN (HYPERTHERMOPHILE CHROMOSOMAL PROTEIN SAC7D)
Authors:Robinson, H., Gao, Y.-G., Mccrary, B.S., Edmondson, S.P., Shriver, J.W., Wang, A.H.-J.
Deposit date:1997-11-20
Release date:1999-01-13
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.94 Å)
Cite:The hyperthermophile chromosomal protein Sac7d sharply kinks DNA.
Nature, 392, 1998
1BNZ
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SSO7D HYPERTHERMOPHILE PROTEIN/DNA COMPLEX
Descriptor:5'-D(*GP*TP*AP*AP*TP*TP*AP*C)-3', DNA-BINDING PROTEIN 7A
Authors:Gao, Y.-G., Su, S.-Y., Robinson, H., Padmanabhan, S., Lim, L., Mccrary, B.S., Edmondos, S.P., Shrive, J.W., Wang, A.H.-J.
Deposit date:1998-07-31
Release date:1998-11-11
Last modified:2017-10-04
Method:X-RAY DIFFRACTION (2 Å)
Cite:The crystal structure of the hyperthermophile chromosomal protein Sso7d bound to DNA.
Nat.Struct.Biol., 5, 1998
1BXL
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STRUCTURE OF BCL-XL/BAK PEPTIDE COMPLEX, NMR, MINIMIZED AVERAGE STRUCTURE
Descriptor:BCL-XL, BAK PEPTIDE
Authors:Sattler, M., Liang, H., Nettesheim, D., Meadows, R.P., Harlan, J.E., Eberstadt, M., Yoon, H., Shuker, S.B., Chang, B.S., Minn, A.J., Thompson, C.B., Fesik, S.W.
Deposit date:1996-10-16
Release date:1997-10-29
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Structure of Bcl-xL-Bak peptide complex: recognition between regulators of apoptosis.
Science, 275, 1997
1CV9
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NMR STUDY OF ITAM PEPTIDE SUBSTRATE
Descriptor:IG-ALPHA ITAM PEPTIDE
Authors:Gaul, B.S., Harrison, M.L., Geahlen, R.L., Post, C.B.
Deposit date:1999-08-23
Release date:1999-08-31
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Substrate recognition by the Lyn protein-tyrosine kinase. NMR structure of the immunoreceptor tyrosine-based activation motif signaling region of the B cell antigen receptor.
J.Biol.Chem., 275, 2000
1DMJ
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BOVINE ENDOTHELIAL NITRIC OXIDE SYNTHASE HEME DOMAIN COMPLEXED WITH 5,6-CYCLIC-TETRAHYDROPTERIDINE
Descriptor:NITRIC OXIDE SYNTHASE, ACETATE ION, CACODYLATE ION, ...
Authors:Kotsonis, P., Frohlich, L.G., Raman, C.S., Li, H., Berg, M., Gerwig, R., Groehn, V., Kang, Y., Al-Masoudi, N., Taghavi-Moghadam, S., Mohr, D., Munch, U., Schnabel, J., Martasek, P., Masters, B.S., Strobel, H., Poulos, T., Matter, H., Pfleiderer, W., Schmidt, H.H.
Deposit date:1999-12-14
Release date:2000-12-20
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.35 Å)
Cite:Structural basis for pterin antagonism in nitric-oxide synthase. Development of novel 4-oxo-pteridine antagonists of (6R)-5,6,7,8-tetrahydrobiopterin
J.Biol.Chem., 276, 2001
1DMK
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BOVINE ENDOTHELIAL NITRIC OXIDE SYNTHASE HEME DOMAIN COMPLEXED WITH 4-AMINO-6-PHENYL-TETRAHYDROPTERIDINE
Descriptor:NITRIC OXIDE SYNTHASE, ACETATE ION, CACODYLATE ION, ...
Authors:Kotsonis, P., Frohlich, L.G., Raman, C.S., Li, H., Berg, M., Gerwig, R., Groehn, V., Kang, Y., Al-Masoudi, N., Taghavi-Moghadam, S., Mohr, D., Munch, U., Schnabel, J., Martasek, P., Masters, B.S., Strobel, H., Poulos, T., Matter, H., Pfleiderer, W., Schmidt, H.H.
Deposit date:1999-12-14
Release date:2000-12-20
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structural basis for pterin antagonism in nitric-oxide synthase. Development of novel 4-oxo-pteridine antagonists of (6R)-5,6,7,8-tetrahydrobiopterin
J.Biol.Chem., 276, 2001
1E6A
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FLUORIDE-INHIBITED SUBSTRATE COMPLEX OF SACCHAROMYCES CEREVISIAE INORGANIC PYROPHOSPHATASE
Descriptor:INORGANIC PYROPHOSPHATASE, MANGANESE (II) ION, PYROPHOSPHATE 2-, ...
Authors:Heikinheimo, P., Tuominen, V., Ahonen, A.-K., Teplyakov, A., Cooperman, B.S., Baykov, A.A., Lahti, R., Goldman, A.
Deposit date:2000-08-09
Release date:2001-03-19
Last modified:2018-12-12
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Toward a quantum-mechanical description of metal-assisted phosphoryl transfer in pyrophosphatase.
Proc. Natl. Acad. Sci. U.S.A., 98, 2001