Author results

1LHW
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CRYSTAL STRUCTURE OF THE N-TERMINAL LG-DOMAIN OF SHBG IN COMPLEX WITH 2-METHOXYESTRADIOL
Descriptor:SEX HORMONE-BINDING GLOBULIN, CALCIUM ION, 1,3,5(10)-ESTRATRIEN-2,3,17-BETA-TRIOL 2-METHYL ETHER, ...
Authors:Avvakumov, G.V., Grishkovskaya, I., Muller, Y.A., Hammond, G.L.
Deposit date:2002-04-17
Release date:2002-10-23
Last modified:2017-10-11
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Crystal structure of human sex hormone-binding globulin in complex with 2-methoxyestradiol reveals the molecular basis for high affinity interactions with C-2 derivatives of estradiol.
J.Biol.Chem., 277, 2002
2A9U
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STRUCTURE OF THE N-TERMINAL DOMAIN OF HUMAN UBIQUITIN CARBOXYL-TERMINAL HYDROLASE 8 (USP8)
Descriptor:Ubiquitin carboxyl-terminal hydrolase 8
Authors:Walker, J.R., Avvakumov, G.V., Xue, S., Newman, E.M., Mackenzie, F., Weigelt, J., Sundstrom, M., Arrowsmith, C., Edwards, E., Bochkarev, A., Dhe-Paganon, S., Structural Genomics Consortium (SGC)
Deposit date:2005-07-12
Release date:2005-08-16
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Amino-terminal Dimerization, NRDP1-Rhodanese Interaction, and Inhibited Catalytic Domain Conformation of the Ubiquitin-specific Protease 8 (USP8).
J.Biol.Chem., 281, 2006
2FZP
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CRYSTAL STRUCTURE OF THE USP8 INTERACTION DOMAIN OF HUMAN NRDP1
Descriptor:ring finger protein 41 isoform 1
Authors:Walker, J.R., Avvakumov, G.V., Xue, S., Newman, E.M., Butler-Cole, C., Finerty Jr., P.J., Weigelt, J., Sundstrom, M., Arrowsmith, C., Edwards, A., Bochkarev, A., Dhe-Paganon, S., Structural Genomics Consortium (SGC)
Deposit date:2006-02-10
Release date:2006-03-28
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.87 Å)
Cite:Amino-terminal Dimerization, NRDP1-Rhodanese Interaction, and Inhibited Catalytic Domain Conformation of the Ubiquitin-specific Protease 8 (USP8).
J.Biol.Chem., 281, 2006
2GFO
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STRUCTURE OF THE CATALYTIC DOMAIN OF HUMAN UBIQUITIN CARBOXYL-TERMINAL HYDROLASE 8
Descriptor:Ubiquitin carboxyl-terminal hydrolase 8, ZINC ION
Authors:Walker, J.R., Avvakumov, G.V., Xue, S., Newman, E.M., Finerty Jr., P.J., Butler-Cole, C., Weigelt, J., Sundstrom, M., Arrowsmith, C., Edwards, A., Bochkarev, A., Dhe-Paganon, S., Structural Genomics Consortium (SGC)
Deposit date:2006-03-22
Release date:2006-04-04
Last modified:2018-01-24
Method:X-RAY DIFFRACTION (2 Å)
Cite:Amino-terminal Dimerization, NRDP1-Rhodanese Interaction, and Inhibited Catalytic Domain Conformation of the Ubiquitin-specific Protease 8 (USP8).
J.Biol.Chem., 281, 2006
2GWF
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STRUCTURE OF A USP8-NRDP1 COMPLEX
Descriptor:Ubiquitin carboxyl-terminal hydrolase 8, RING finger protein 41
Authors:Walker, J.R., Avvakumov, G.V., Xue, S., Newman, E.M., Butler-Cole, C., Finerty Jr., P.J., Weigelt, J., Sundstrom, M., Arrowsmith, C.H., Edwards, A.M., Bochkarev, A., Dhe-Paganon, S., Structural Genomics Consortium (SGC)
Deposit date:2006-05-04
Release date:2006-06-06
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Amino-terminal Dimerization, NRDP1-Rhodanese Interaction, and Inhibited Catalytic Domain Conformation of the Ubiquitin-specific Protease 8 (USP8).
J.Biol.Chem., 281, 2006
2I6T
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ORTHORHOMBIC STRUCTURE OF THE LDH DOMAIN OF HUMAN UBIQUITIN-CONJUGATING ENZYME E2-LIKE ISOFORM A
Descriptor:UBIQUITIN-CONJUGATING ENZYME E2-LIKE ISOFORM A, SULFATE ION, GLYCEROL
Authors:Walker, J.R., Avvakumov, G.V., Xue, S., Newman, E.M., Finerty Jr., P.J., Butler-Cole, C., Tempel, W., Weigelt, J., Sundstrom, M., Arrowsmith, C.H., Edwards, A.M., Bochkarev, A., Dhe-Paganon, S.
Deposit date:2006-08-29
Release date:2006-10-24
Last modified:2017-10-18
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structural Investigation into the L-lactate Dehydrogenase Domain of Human Ubiquitin-conjugating Enzyme E2-like Isoform A
To be Published
2IBI
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COVALENT UBIQUITIN-USP2 COMPLEX
Descriptor:Ubiquitin carboxyl-terminal hydrolase 2, Ubiquitin, ZINC ION, ...
Authors:Walker, J.R., Avvakumov, G.V., Bernstein, G., Xue, S., Finerty Jr., P.J., MacKenzie, F., Weigelt, J., Sundstrom, M., Arrowsmith, C.H., Edwards, A.M., Bochkarev, A., Dhe-Paganon, S., Structural Genomics Consortium (SGC)
Deposit date:2006-09-11
Release date:2006-10-24
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Covalent Ubiquitin-USP2 Complex
To be Published
3BI7
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CRYSTAL STRUCTURE OF THE SRA DOMAIN OF E3 UBIQUITIN-PROTEIN LIGASE UHRF1
Descriptor:E3 ubiquitin-protein ligase UHRF1, SULFATE ION, 1,2-ETHANEDIOL, ...
Authors:Walker, J.R., Avvakumov, G.V., Xue, S., Li, Y., Weigelt, J., Arrowsmith, C.H., Edwards, A.M., Bochkarev, A., Dhe-Paganon, S., Structural Genomics Consortium (SGC)
Deposit date:2007-11-30
Release date:2007-12-18
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Structural basis for recognition of hemi-methylated DNA by the SRA domain of human UHRF1.
Nature, 455, 2008
3CLZ
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THE SET AND RING ASSOCIATED (SRA) DOMAIN OF UHRF1 BOUND TO METHYLATED DNA
Descriptor:E3 ubiquitin-protein ligase UHRF1, 5'-D(*DGP*DGP*DGP*DCP*DCP*(5CM)P*DGP*DCP*DAP*DGP*DGP*DG)-3', 5'-D(*DCP*DCP*DCP*DTP*DGP*DCP*DGP*DGP*DGP*DCP*DCP*DC)-3'
Authors:Walker, J.R., Avvakumov, G.V., Xue, S., Dong, A., Li, Y., Bountra, C., Weigelt, J., Arrowsmith, C.H., Edwards, A.M., Bochkarev, A., Dhe-Paganon, S., Structural Genomics Consortium (SGC)
Deposit date:2008-03-20
Release date:2008-04-29
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structural basis for recognition of hemi-methylated DNA by the SRA domain of human UHRF1.
Nature, 455, 2008
1D2S
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CRYSTAL STRUCTURE OF THE N-TERMINAL LAMININ G-LIKE DOMAIN OF SHBG IN COMPLEX WITH DIHYDROTESTOSTERONE
Descriptor:SEX HORMONE-BINDING GLOBULIN, CALCIUM ION, 5-ALPHA-DIHYDROTESTOSTERONE
Authors:Grishkovskaya, I., Avvakumov, G.V., Sklenar, G., Dales, D., Hammond, G.L., Muller, Y.A.
Deposit date:1999-09-28
Release date:2000-06-28
Last modified:2018-01-31
Method:X-RAY DIFFRACTION (1.55 Å)
Cite:Crystal structure of human sex hormone-binding globulin: steroid transport by a laminin G-like domain.
EMBO J., 19, 2000
1KDK
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THE STRUCTURE OF THE N-TERMINAL LG DOMAIN OF SHBG IN CRYSTALS SOAKED WITH EDTA
Descriptor:Sex Hormone-Binding Globulin, 5-ALPHA-DIHYDROTESTOSTERONE
Authors:Grishkovskaya, I., Avvakumov, G.V., Hammond, G.L., Muller, Y.A.
Deposit date:2001-11-13
Release date:2002-05-15
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Resolution of a disordered region at the entrance of the human sex hormone-binding globulin steroid-binding site.
J.Mol.Biol., 318, 2002
1KDM
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THE CRYSTAL STRUCTURE OF THE HUMAN SEX HORMONE-BINDING GLOBULIN (TETRAGONAL CRYSTAL FORM)
Descriptor:sex hormone-binding globulin, CALCIUM ION, 5-ALPHA-DIHYDROTESTOSTERONE
Authors:Grishkovskaya, I., Avvakumov, G.V., Hammond, G.L., Muller, Y.A.
Deposit date:2001-11-13
Release date:2002-05-15
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.35 Å)
Cite:Resolution of a disordered region at the entrance of the human sex hormone-binding globulin steroid-binding site.
J.Mol.Biol., 318, 2002
1LHN
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CRYSTAL STRUCTURE OF THE N-TERMINAL LG-DOMAIN OF SHBG IN COMPLEX WITH 5ALPHA-ANDROSTANE-3BETA,17ALPHA-DIOL
Descriptor:SEX HORMONE-BINDING GLOBULIN, CALCIUM ION, ZINC ION, ...
Authors:Grishkovskaya, I., Avvakumov, G.V., Hammond, G.L., Catalano, M.G., Muller, Y.A.
Deposit date:2002-04-17
Release date:2002-10-23
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Steroid Ligands Bind Human Sex Hormone-binding Globulin in Specific Orientations and Produce Distinct Changes in Protein Conformation
J.Biol.Chem., 277, 2002
1LHO
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CRYSTAL STRUCTURE OF THE N-TERMINAL LG-DOMAIN OF SHBG IN COMPLEX WITH 5ALPHA-ANDROSTANE-3BETA,17BETA-DIOL
Descriptor:SEX HORMONE-BINDING GLOBULIN, CALCIUM ION, 5-ALPHA-ANDROSTANE-3-BETA,17BETA-DIOL
Authors:Grishkovskaya, I., Avvakumov, G.V., Hammond, G.L., Catalano, M.G., Muller, Y.A.
Deposit date:2002-04-17
Release date:2002-10-23
Last modified:2017-10-11
Method:X-RAY DIFFRACTION (2 Å)
Cite:Steroid Ligands Bind Human Sex Hormone-binding Globulin in Specific Orientations and Produce Distinct Changes in Protein Conformation
J.Biol.Chem., 277, 2002
1LHU
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CRYSTAL STRUCTURE OF THE N-TERMINAL LG-DOMAIN OF SHBG IN COMPLEX WITH ESTRADIOL
Descriptor:SEX HORMONE-BINDING GLOBULIN, CALCIUM ION, ESTRADIOL
Authors:Grishkovskaya, I., Avvakumov, G.V., Hammond, G.L., Catalano, M.G., Muller, Y.A.
Deposit date:2002-04-17
Release date:2002-10-23
Last modified:2017-10-11
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Steroid Ligands Bind Human Sex Hormone-binding Globulin in Specific Orientations and Produce Distinct Changes in Protein Conformation
J.Biol.Chem., 277, 2002
1LHV
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CRYSTAL STRUCTURE OF THE N-TERMINAL LG-DOMAIN OF SHBG IN COMPLEX WITH NORGESTREL
Descriptor:SEX HORMONE-BINDING GLOBULIN, CALCIUM ION, ZINC ION, ...
Authors:Grishkovskaya, I., Avvakumov, G.V., Hammond, G.L., Catalano, M.G., Muller, Y.A.
Deposit date:2002-04-17
Release date:2002-10-23
Last modified:2017-10-11
Method:X-RAY DIFFRACTION (2 Å)
Cite:Steroid Ligands Bind Human Sex Hormone-binding Globulin in Specific Orientations and Produce Distinct Changes in Protein Conformation
J.Biol.Chem., 277, 2002
1Y6L
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HUMAN UBIQUITIN CONJUGATING ENZYME E2E2
Descriptor:Ubiquitin-conjugating enzyme E2E2
Authors:Walker, J.R., Avvakumov, G.V., Newman, E.M., Mackenzie, F., Kozieradzki, I., Bochkarev, A., Sundstrom, M., Arrowsmith, C., Edwards, A., Dhe-Paganon, S., Structural Genomics Consortium (SGC)
Deposit date:2004-12-06
Release date:2005-01-11
Last modified:2012-11-28
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:A human ubiquitin conjugating enzyme (E2)-HECT E3 ligase structure-function screen.
Mol Cell Proteomics, 11, 2012
1YH2
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UBIQUITIN-CONJUGATING ENZYME HSPC150
Descriptor:HSPC150 protein similar to ubiquitin-conjugating enzyme
Authors:Walker, J.R., Avvakumov, G.V., Newman, E.M., Mackenzie, F., Kozieradzki, I., Sundstrom, M., Arrowsmith, C., Edwards, A., Bochkarev, A., Dhe-paganon, S., Structural Genomics Consortium (SGC)
Deposit date:2005-01-06
Release date:2005-02-15
Last modified:2012-11-28
Method:X-RAY DIFFRACTION (2 Å)
Cite:A human ubiquitin conjugating enzyme (E2)-HECT E3 ligase structure-function screen.
Mol Cell Proteomics, 11, 2012
1YLA
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UBIQUITIN-CONJUGATING ENZYME E2-25 KDA (HUNTINGTON INTERACTING PROTEIN 2)
Descriptor:Ubiquitin-conjugating enzyme E2-25 kDa
Authors:Choe, J., Avvakumov, G.V., Newman, E.M., Mackenzie, F., Kozieradzki, I., Bochkarev, A., Sundstrom, M., Arrowsmith, C., Edwards, A., Dhe-paganon, S., Structural Genomics Consortium (SGC)
Deposit date:2005-01-19
Release date:2005-02-01
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Structural basis of E2-25K/UBB+1 interaction leading to proteasome inhibition and neurotoxicity
J.Biol.Chem., 285, 2010
1YQB
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HUMAN UBIQUILIN 3
Descriptor:Ubiquilin 3
Authors:Walker, J.R., Xue, S., Avvakumov, G.V., Newman, E.M., Mackenzie, F., Sundstrom, M., Arrowsmith, C., Edwards, A., Bochkarev, A., Dhe-Paganon, S., Structural Genomics Consortium (SGC)
Deposit date:2005-02-01
Release date:2005-02-08
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:The Ubiquitin-like domain of Human Ubiquilin 3
To be Published
1YRV
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NOVEL UBIQUITIN-CONJUGATING ENZYME
Descriptor:ubiquitin-conjugating ligase MGC351130
Authors:Walker, J.R., Choe, J., Avvakumov, G.V., Newman, E.M., MacKenzie, F., Sundstrom, M., Arrowsmith, C., Edwards, A., Bochkarev, A., Dhe-Paganon, S., Structural Genomics Consortium (SGC)
Deposit date:2005-02-04
Release date:2005-03-22
Last modified:2012-11-28
Method:X-RAY DIFFRACTION (2.18 Å)
Cite:A human ubiquitin conjugating enzyme (E2)-HECT E3 ligase structure-function screen.
Mol Cell Proteomics, 11, 2012
1Z6U
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NP95-LIKE RING FINGER PROTEIN ISOFORM B [HOMO SAPIENS]
Descriptor:Np95-like ring finger protein isoform b, ZINC ION
Authors:Walker, J.R., Avvakumov, G.V., Xue, S., Newman, E.M., Mackenzie, F., Sundstrom, M., Arrowsmith, C., Edwards, A., Bochkarev, A., Dhe-Paganon, S., Structural Genomics Consortium (SGC)
Deposit date:2005-03-23
Release date:2005-05-03
Last modified:2017-10-11
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:2.1 Angstrom Crystal Structure of the Human Ubiquitin Liagse NIRF
To be Published
1ZDN
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UBIQUITIN-CONJUGATING ENZYME E2S
Descriptor:Ubiquitin-conjugating enzyme E2S, SODIUM ION
Authors:Walker, J.R., Avvakumov, G.V., Xue, S., Newman, E.M., Mackenzie, F., Sundstrom, M., Arrowsmith, C., Edwards, A., Bochkarev, A., Dhe-Paganon, S., Structural Genomics Consortium (SGC)
Deposit date:2005-04-14
Release date:2005-05-03
Last modified:2012-11-28
Method:X-RAY DIFFRACTION (1.93 Å)
Cite:A human ubiquitin conjugating enzyme (E2)-HECT E3 ligase structure-function screen.
Mol Cell Proteomics, 11, 2012
1ZKH
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SOLUTION STRUCTURE OF A HUMAN UBIQUITIN-LIKE DOMAIN IN SF3A1
Descriptor:Splicing factor 3 subunit 1
Authors:Lukin, J.A., Dhe-Paganon, S., Guido, V., Lemak, A., Avvakumov, G.V., Xue, S., Newman, E.M., Mackenzie, F., Sundstrom, M., Edwards, A., Arrowsmith, C.H., Structural Genomics Consortium (SGC)
Deposit date:2005-05-02
Release date:2005-05-10
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Solution structure of a human ubiquitin-like domain in SF3A1
To be Published
1ZUO
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STRUCTURE OF HUMAN UBIQUITIN-CONJUGATING ENZYME (UBCI) INVOLVED IN EMBRYO ATTACHMENT AND IMPLANTATION
Descriptor:Hypothetical protein LOC92912, BETA-MERCAPTOETHANOL
Authors:Walker, J.R., Avvakumov, G.V., Cui, H., Newman, E.M., Mackenzie, F., Sundstrom, M., Arrowsmith, C., Edwards, A., Bochkarev, A., Dhe-Paganon, S., Structural Genomics Consortium (SGC)
Deposit date:2005-05-31
Release date:2005-07-05
Last modified:2012-11-28
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:A human ubiquitin conjugating enzyme (E2)-HECT E3 ligase structure-function screen.
Mol Cell Proteomics, 11, 2012
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