Author results

3RQ3
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STRUCTURE OF T-CELL IMMUNORECEPTOR WITH IMMUNOGLOBULIN AND ITIM DOMAINS (TIGIT) IN HEXAGONAL CRYSTAL FORM
Descriptor:T cell immunoreceptor with Ig and ITIM domains, CHLORIDE ION
Authors:Ramagopal, U.A., Rubinstein, R., Guo, H., Samanta, D., Nathenson, S.G., Almo, S.C., New York Structural Genomics Research Consortium (NYSGRC), Atoms-to-Animals: The Immune Function Network (IFN)
Deposit date:2011-04-27
Release date:2011-06-01
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Structure of T-cell immunoreceptor with immunoglobulin and ITIM domains (TIGIT) in hexagonal crystal form
To be published
4G4F
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CRYSTAL STRUCTURE OF GITRL FROM BUSHBABY
Descriptor:Tumor necrosis factor ligand superfamily member 18
Authors:Kumar, P.R., Bhosle, R., Nathenson, S.G., Almo, S.C., New York Structural Genomics Research Consortium (NYSGRC), Atoms-to-Animals: The Immune Function Network (IFN)
Deposit date:2012-07-16
Release date:2012-08-01
Method:X-RAY DIFFRACTION (1.847 Å)
Cite:Crystal structure of GITRL from Otolemur garnettii
to be published
4JJH
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CRYSTAL STRUCTURE OF THE D1 DOMAIN FROM HUMAN NECTIN-4 EXTRACELLULAR FRAGMENT [PSI-NYSGRC-005624]
Descriptor:Poliovirus receptor-related protein 4, 1,2-ETHANEDIOL
Authors:Kumar, P.R., Bonanno, J., Ahmed, M., Banu, R., Bhosle, R., Calarese, D., Celikigil, A., Chamala, S., Chan, M.K., Chowdhury, S., Fiser, A., Garforth, S., Glenn, A.S., Hillerich, B., Khafizov, K., Love, J., Patel, H., Seidel, R., Stead, M., Toro, R., Nathenson, S.G., Almo, S.C., New York Structural Genomics Research Consortium (NYSGRC), Atoms-to-Animals: The Immune Function Network (IFN)
Deposit date:2013-03-07
Release date:2013-03-27
Last modified:2017-11-15
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:Crystal structure of the D1 domain of human Nectin-4 extracellular fragment [NYSGRC-005624]
to be published
4NOB
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CRYSTAL STRUCTURE OF THE 1ST IG DOMAIN FROM MOUSE POLYMERIC IMMUNOGLOBULIN RECEPTOR [PSI-NYSGRC-006220]
Descriptor:Polymeric immunoglobulin receptor, N-ACETYL-D-GLUCOSAMINE, MAGNESIUM ION, ...
Authors:Kumar, P.R., Banu, R., Bhosle, R., Calarese, D.A., Celikgil, A., Chamala, S., Chan, M.K., Chowdhury, S., Fiser, A., Garforth, S.J., Glenn, A.S., Hillerich, B., Khafizov, K., Attonito, J., Love, J.D., Patel, H., Patel, R., Seidel, R.D., Smith, B., Stead, M., Casadevall, A., Almo, S.C., New York Structural Genomics Research Consortium (NYSGRC), Atoms-to-Animals: The Immune Function Network (IFN)
Deposit date:2013-11-19
Release date:2013-12-04
Method:X-RAY DIFFRACTION (1.51 Å)
Cite:Crystal structure of the 1st Ig domain from mouse Polymeric Immunoglobulin receptor
to be published
4NOF
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CRYSTAL STRUCTURE OF THE SECOND IG DOMAIN FROM MOUSE POLYMERIC IMMUNOGLOBULIN RECEPTOR [PSI-NYSGRC-006220]
Descriptor:Polymeric immunoglobulin receptor, N-ACETYL-D-GLUCOSAMINE, GLYCEROL
Authors:Sampathkumar, P., Kumar, P.R., Ahmed, M., Banu, R., Bhosle, R., Calarese, D.A., Celikgil, A., Chamala, S., Chan, M.K., Chowdhury, S., Fiser, A., Garforth, S.J., Glenn, A.S., Hillerich, B., Khafizov, K., Attonito, J., Love, J.D., Patel, H., Patel, R., Seidel, R.D., Smith, B., Stead, M., Casadevall, A., Almo, S.C., New York Structural Genomics Research Consortium (NYSGRC), Atoms-to-Animals: The Immune Function Network (IFN)
Deposit date:2013-11-19
Release date:2013-12-04
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:Crystal structure of the second Ig domain from mouse Polymeric Immunoglobulin receptor
to be published
3RBG
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CRYSTAL STRUCTURE ANALYSIS OF CLASS-I MHC RESTRICTED T-CELL ASSOCIATED MOLECULE
Descriptor:Cytotoxic and regulatory T-cell molecule, PHOSPHATE ION
Authors:Rubinstein, R., Ramagopal, U.A., Toro, R., Nathenson, S.G., Fiser, A., Almo, S.C., New York Structural Genomics Research Consortium (NYSGRC), Atoms-to-Animals: The Immune Function Network (IFN)
Deposit date:2011-03-29
Release date:2011-05-25
Last modified:2017-10-25
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Functional classification of immune regulatory proteins.
Structure, 21, 2013
4FHQ
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CRYSTAL STRUCTURE OF HVEM
Descriptor:Tumor necrosis factor receptor superfamily member 14
Authors:Liu, W., Zhan, C., Patskovsky, Y., Bhosle, R.C., Nathenson, S.G., Almo, S.C., Atoms-to-Animals: The Immune Function Network (IFN), New York Structural Genomics Research Consortium (NYSGRC)
Deposit date:2012-06-06
Release date:2012-07-18
Last modified:2015-09-16
Method:X-RAY DIFFRACTION (2.251 Å)
Cite:Increased Heterologous Protein Expression in Drosophila S2 Cells for Massive Production of Immune Ligands/Receptors and Structural Analysis of Human HVEM.
Mol Biotechnol, 57, 2015
4GOS
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CRYSTAL STRUCTURE OF HUMAN B7-H4 IGV-LIKE DOMAIN
Descriptor:V-set domain-containing T-cell activation inhibitor 1, N-ACETYL-D-GLUCOSAMINE, BETA-D-MANNOSE, ...
Authors:Vigdorovich, V., Ramagopal, U., Bhosle, R., Toro, R., Nathenson, S.G., Almo, S.C., New York Structural Genomics Research Consortium (NYSGRC), Atoms-to-Animals: The Immune Function Network (IFN)
Deposit date:2012-08-20
Release date:2012-09-12
Last modified:2016-11-16
Method:X-RAY DIFFRACTION (1.59 Å)
Cite:Structure and cancer immunotherapy of the B7 family member B7x.
Cell Rep, 9, 2014
4KKN
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CRYSTAL STRUCTURE OF BOVINE CTLA-4, PSI-NYSGRC-012704
Descriptor:Cytotoxic T-lymphocyte associated protein 4, N-ACETYL-D-GLUCOSAMINE, BETA-D-MANNOSE, ...
Authors:Kumar, P.R., Ahmed, M., Banu, R., Bhosle, R., Bonanno, J., Calarese, D.A., Celikgil, A., Chamala, S., Chan, M.K., Chowdhury, S., Fiser, A., Garforth, S.J., Scott Glenn, A., Hammonds, J., Hillerich, B., Khafizov, K., Lafleur, J., Attonito, J., Love, J.D., Patel, H., Patel, R., Seidel, R.D., Smith, B., Stead, M., Toro, R., Casadevall, A., Almo, S.C., New York Structural Genomics Research Consortium (NYSGRC), Atoms-to-Animals: The Immune Function Network (IFN)
Deposit date:2013-05-06
Release date:2013-06-12
Last modified:2017-11-15
Method:X-RAY DIFFRACTION (2.253 Å)
Cite:Crystal structure of bovine CTLA-4, PSI-NYSGRC-012704
to be published
4N8P
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CRYSTAL STRUCTURE OF A STRAND SWAPPED CTLA-4 FROM DUCKBILL PLATYPUS [PSI-NYSGRC-012711]
Descriptor:Uncharacterized protein, GLYCEROL, N-ACETYL-D-GLUCOSAMINE
Authors:Kumar, P.R., Banu, R., Bhosle, R., Calarese, D.A., Celikgil, A., Chamala, S., Chan, M.K., Chowdhury, S., Fiser, A., Garforth, S.J., Glenn, A.S., Hillerich, B., Khafizov, K., Attonito, J., Love, J.D., Patel, H., Patel, R., Seidel, R.D., Smith, B., Stead, M., Toro, R., Casadevall, A., Almo, S.C., New York Structural Genomics Research Consortium (NYSGRC), Atoms-to-Animals: The Immune Function Network (IFN)
Deposit date:2013-10-17
Release date:2013-10-30
Method:X-RAY DIFFRACTION (2.299 Å)
Cite:Crystal structure of a strand swapped CTLA-4 from Duckbill Platypus [PSI-NYSGRC-012711]
to be published
4RSU
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CRYSTAL STRUCTURE OF THE LIGHT AND HVEM COMPLEX
Descriptor:Tumor necrosis factor ligand superfamily member 14, soluble form, Tumor necrosis factor receptor superfamily member 14, ...
Authors:Liu, W., Ramagoal, U.A., Himmel, D., Bonanno, J.B., Nathenson, S.G., Almo, S.C., Atoms-to-Animals: The Immune Function Network (IFN), New York Structural Genomics Research Consortium (NYSGRC)
Deposit date:2014-11-11
Release date:2015-02-04
Last modified:2015-02-11
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Crystal Structure of the Light and Hvem Complex
To be Published
3R0N
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CRYSTAL STRUCTURE OF THE IMMUNOGLOBULIN VARIABLE DOMAIN OF NECTIN-2
Descriptor:Poliovirus receptor-related protein 2, MAGNESIUM ION, CHLORIDE ION
Authors:Ramagopal, U.A., Samanta, D., Nathenson, S.G., Almo, S.C., New York Structural Genomics Research Consortium (NYSGRC), Atoms-to-Animals: The Immune Function Network (IFN)
Deposit date:2011-03-08
Release date:2011-04-27
Last modified:2012-11-07
Method:X-RAY DIFFRACTION (1.3 Å)
Cite:Structure of Nectin-2 reveals determinants of homophilic and heterophilic interactions that control cell-cell adhesion.
Proc.Natl.Acad.Sci.USA, 109, 2012
4DB5
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CRYSTAL STRUCTURE OF RABBIT GITRL
Descriptor:Tumor necrosis factor ligand superfamily member 18, 2-[3-(2-HYDROXY-1,1-DIHYDROXYMETHYL-ETHYLAMINO)-PROPYLAMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL
Authors:Kumar, P.R., Bhosle, R., Gizzi, A., Scott Glenn, A., Chowhury, S., Hillerich, B., Seidel, R., Nathenson, S.G., Almo, S.C., New York Structural Genomics Research Consortium (NYSGRC), Atoms-to-Animals: The Immune Function Network (IFN)
Deposit date:2012-01-13
Release date:2012-03-21
Last modified:2012-06-06
Method:X-RAY DIFFRACTION (1.522 Å)
Cite:Crystal structure of GITRL from Oryctolagus cuniculus
to be published
4E4S
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CRYSTAL STRUCTURE OF PIKA GITRL
Descriptor:Tumor necrosis factor ligand superfamily member 18, GLYCEROL, MAGNESIUM ION
Authors:Kumar, P.R., Bhosle, R., Bonanno, J., Chowdhury, S., Gizzi, A., Glen, S., Hillerich, B., Hammonds, J., Seidel, R., Toro, R., Nathenson, S.G., Almo, S.C., New York Structural Genomics Research Consortium (NYSGRC), Atoms-to-Animals: The Immune Function Network (IFN)
Deposit date:2012-03-13
Release date:2012-03-21
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Crystal structure of GITRL from Ochotona princeps
to be published
4ESK
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CRYSTAL STRUCTURE OF A STRAND-SWAPPED DIMER OF MOUSE LEUKOCYTE-ASSOCIATED IMMUNOGLOBULIN-LIKE RECEPTOR 1 (NYSGRC-006047)IG-LIKE DOMAIN
Descriptor:Leukocyte-associated immunoglobulin-like receptor 1, GLYCEROL, POTASSIUM ION, ...
Authors:Sampathkumar, P., Almo, S.C., New York Structural Genomics Research Consortium (NYSGRC), Atoms-to-Animals: The Immune Function Network (IFN)
Deposit date:2012-04-23
Release date:2012-05-02
Method:X-RAY DIFFRACTION (1.762 Å)
Cite:Crystal structure of a strand-swapped dimer of Mouse Leukocyte-associated immunoglobulin-like receptor 1 IG-like domain
to be published
4ETY
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CRYSTAL STRUCTURE OF A STRAND-SWAPPED DIMER OF MOUSE LEUKOCYTE-ASSOCIATED IMMUNOGLOBULIN-LIKE RECEPTOR 1 (NYSGRC-006047) EXTRA CELLULAR DOMAIN
Descriptor:Leukocyte-associated immunoglobulin-like receptor 1, 1,2-ETHANEDIOL
Authors:Sampathkumar, P., Almo, S.C., New York Structural Genomics Research Consortium (NYSGRC), Atoms-to-Animals: The Immune Function Network (IFN)
Deposit date:2012-04-24
Release date:2012-06-06
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Crystal structure of a strand-swapped dimer of Mouse Leukocyte-associated immunoglobulin-like receptor 1 Extra Cellular Domain
to be published
4HZA
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CRYSTAL STRUCTURE OF THE IMMUNOGLOBULIN VARIABLE DOMAIN OF NECTIN-2 IN MONOCLINIC FORM
Descriptor:Poliovirus receptor-related protein 2
Authors:Ramagopal, U.A., Samanta, D., Nathenson, S.G., Almo, S.C., New York Structural Genomics Research Consortium (NYSGRC), Atoms-to-Animals: The Immune Function Network (IFN)
Deposit date:2012-11-14
Release date:2013-01-30
Last modified:2013-02-06
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Crystal Structure of the Immunoglobulin variable domain of Nectin-2 in monoclinic form
To be published
4I0K
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CRYSTAL STRUCTURE OF MURINE B7-H3 EXTRACELLULAR DOMAIN
Descriptor:CD276 antigen, N-ACETYL-D-GLUCOSAMINE, BETA-D-MANNOSE, ...
Authors:Vigdorovich, V., Ramagopal, U., Bonanno, J.B., Toro, R., Nathenson, S.G., Almo, S.C., New York Structural Genomics Research Consortium (NYSGRC), Atoms-to-Animals: The Immune Function Network (IFN)
Deposit date:2012-11-16
Release date:2012-12-05
Last modified:2016-11-16
Method:X-RAY DIFFRACTION (2.97 Å)
Cite:Structure and T cell inhibition properties of B7 family member, B7-H3.
Structure, 21, 2013
4J6G
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CRYSTAL STRUCTURE OF LIGHT AND DCR3 COMPLEX
Descriptor:Tumor necrosis factor ligand superfamily member 14, Tumor necrosis factor receptor superfamily member 6B, CHLORIDE ION, ...
Authors:Liu, W., Zhan, C., Bonanno, J.B., Bhosle, R.C., Nathenson, S.G., Almo, S.C., Atoms-to-Animals: The Immune Function Network (IFN), New York Structural Genomics Research Consortium (NYSGRC)
Deposit date:2013-02-11
Release date:2013-03-13
Last modified:2014-12-31
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Mechanistic basis for functional promiscuity in the TNF and TNF receptor superfamilies: structure of the LIGHT:DcR3 assembly.
Structure, 22, 2014
4KGQ
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CRYSTAL STRUCTURE OF A HUMAN LIGHT LOOP MUTANT IN COMPLEX WITH DCR3
Descriptor:Tumor necrosis factor receptor superfamily member 6B, Tumor necrosis factor ligand superfamily member 14, MAGNESIUM ION, ...
Authors:Liu, W., Zhan, C., Bonanno, J.B., Sampathkumar, P., Toro, R., Nathenson, S.G., Almo, S.C., New York Structural Genomics Research Consortium (NYSGRC), Atoms-to-Animals: The Immune Function Network (IFN)
Deposit date:2013-04-29
Release date:2013-07-10
Last modified:2014-12-24
Method:X-RAY DIFFRACTION (2.27 Å)
Cite:Mechanistic basis for functional promiscuity in the TNF and TNF receptor superfamilies: structure of the LIGHT:DcR3 assembly.
Structure, 22, 2014
4MSV
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CRYSTAL STRUCTURE OF FASL AND DCR3 COMPLEX
Descriptor:Tumor necrosis factor receptor superfamily member 6B, Tumor necrosis factor ligand superfamily member 6, MAGNESIUM ION, ...
Authors:Liu, W., Ramagopal, U.A., Zhan, C., Bonanno, J.B., Bhosle, R.C., Nathenson, S.G., Almo, S.C., Atoms-to-Animals: The Immune Function Network (IFN), New York Structural Genomics Research Consortium (NYSGRC)
Deposit date:2013-09-18
Release date:2013-11-27
Last modified:2016-11-16
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Crystal Structure of the Complex of Human FasL and Its Decoy Receptor DcR3.
Structure, 24, 2016
4EN0
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CRYSTAL STRUCTURE OF LIGHT
Descriptor:Tumor necrosis factor ligand superfamily member 14, PHOSPHATE ION, GLYCEROL, ...
Authors:Zhan, C., Liu, W., Patskovsky, Y., Ramagopal, U.A., Bonanno, J.B., Nathenson, S.G., Almo, S.C., New York Structural Genomics Research Consortium (NYSGRC), Atoms-to-Animals: The Immune Function Network (IFN)
Deposit date:2012-04-12
Release date:2012-05-09
Last modified:2014-12-31
Method:X-RAY DIFFRACTION (2.59 Å)
Cite:Mechanistic basis for functional promiscuity in the TNF and TNF receptor superfamilies: structure of the LIGHT:DcR3 assembly.
Structure, 22, 2014
4ETO
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STRUCTURE OF S100A4 IN COMPLEX WITH NON-MUSCLE MYOSIN-IIA PEPTIDE
Descriptor:Protein S100-A4, Myosin-9, CALCIUM ION
Authors:Ramagopal, U.A., Dulyaninova, N.G., Kumar, P.R., Almo, S.C., Bresnick, A.R., New York Structural Genomics Research Consortium (NYSGRC), Atoms-to-Animals: The Immune Function Network (IFN)
Deposit date:2012-04-24
Release date:2012-07-11
Last modified:2012-07-18
Method:X-RAY DIFFRACTION (1.54 Å)
Cite:Structure of S100A4 with bound peptide P
To be Published
4HWN
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CRYSTAL STRUCTURE OF THE SECOND IG-C2 DOMAIN OF HUMAN FC-RECEPTOR LIKE A (FCRLA), ISOFORM 9 [NYSGRC-005836]
Descriptor:Fc receptor-like A
Authors:Kumar, P.R., Ahmed, M., Bhosle, R., Calarese, D., Celikigil, A., Chan, M.K., Fiser, A., Garforth, S., Glenn, A.S., Hillerich, B., Khafizov, K., Love, J., Patel, H., Rubinstein, R., Seidel, R., Stead, M., Toro, R., Nathenson, S.G., Almo, S.C., New York Structural Genomics Research Consortium (NYSGRC), Atoms-to-Animals: The Immune Function Network (IFN)
Deposit date:2012-11-08
Release date:2012-11-21
Method:X-RAY DIFFRACTION (2.006 Å)
Cite:Crystal structure of the second Ig-C2 domain of the human Fc-receptor like A, Isoform 9 [NYSGRC-005836]
to be published
4HWU
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CRYSTAL STRUCTURE OF THE IG-C2 TYPE 1 DOMAIN FROM MOUSE FIBROBLAST GROWTH FACTOR RECEPTOR 2 (FGFR2) [NYSGRC-005912]
Descriptor:Fibroblast growth factor receptor 2
Authors:Kumar, P.R., Ahmed, M., Banu, R., Bhosle, R., Calarese, D., Celikigil, A., Chamala, S., Chan, M.K., Chowdhury, S., Fiser, A., Garforth, S., Glenn, A.S., Hillerich, B., Khafizov, K., Love, J., Patel, H., Rubinstein, R., Seidel, R., Stead, M., Toro, R., Nathenson, S.G., Almo, S.C., New York Structural Genomics Research Consortium (NYSGRC), Atoms-to-Animals: The Immune Function Network (IFN)
Deposit date:2012-11-08
Release date:2012-11-21
Method:X-RAY DIFFRACTION (2.903 Å)
Cite:Crystal structure of the Ig-C2 type 1 domain from mouse FGFR2 [NYSGRC-005912]
to be published
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