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Crystal structure of apo-acyl carrier protein from Leishmania major
Descriptor:	Acyl carrier protein
Authors:	Arya, R, Sharma, B, Makde, R.D, Kundu, S.
Deposit date:	2018-05-16
Release date:	2019-01-16
Last modified:	2023-11-22
Method:	X-RAY DIFFRACTION (2 Å)
Cite:	A conformational switch from a closed apo- to an open holo-form equips the acyl carrier protein for acyl chain accommodation. Biochim Biophys Acta Proteins Proteom, 1867, 2018

Crystal structure of the S37A mutant of apo-acyl carrier protein from Leishmania major
Descriptor:	Acyl carrier protein
Authors:	Sharma, B, Arya, R, Kundu, S, Makde, R.D.
Deposit date:	2018-05-16
Release date:	2019-01-16
Last modified:	2023-11-22
Method:	X-RAY DIFFRACTION (2 Å)
Cite:	A conformational switch from a closed apo- to an open holo-form equips the acyl carrier protein for acyl chain accommodation. Biochim Biophys Acta Proteins Proteom, 1867, 2018

Human ERAP1 bound to phosphinic pseudotripeptide inhibitor DG013
Descriptor:	2-acetamido-2-deoxy-beta-D-glucopyranose, Endoplasmic reticulum aminopeptidase 1, Nalpha-[(2S)-2-{[[(1R)-1-amino-3-phenylpropyl](hydroxy)phosphoryl]methyl}-4-methylpentanoyl]-L-tryptophanamide, ...
Authors:	Maben, Z, Stern, L.J.
Deposit date:	2018-08-22
Release date:	2019-12-18
Last modified:	2023-10-11
Method:	X-RAY DIFFRACTION (3.31 Å)
Cite:	Conformational dynamics linked to domain closure and substrate binding explain the ERAP1 allosteric regulation mechanism. Nat Commun, 12, 2021

ERAP1 in the open conformation bound to 10mer phosphinic inhibitor DG014
Descriptor:	2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Endoplasmic reticulum aminopeptidase 1, Phosphinic inhibitor DG014, ...
Authors:	Stern, L.J, Maben, Z.
Deposit date:	2018-09-14
Release date:	2019-12-18
Last modified:	2023-10-11
Method:	X-RAY DIFFRACTION (2.92 Å)
Cite:	Conformational dynamics linked to domain closure and substrate binding explain the ERAP1 allosteric regulation mechanism. Nat Commun, 12, 2021