1NP8
| 18-k C-terminally trunucated small subunit of calpain | Descriptor: | CADMIUM ION, Calcium-dependent protease, small subunit | Authors: | Leinala, E.K, Arthur, J.S, Grochulski, P, Davies, P.L, Elce, J.S, Jia, Z. | Deposit date: | 2003-01-17 | Release date: | 2003-11-18 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | A second binding site revealed by C-terminal truncation of calpain small subunit, a penta-EF-hand protein PROTEINS: STRUCT.,FUNCT.,GENET., 53, 2003
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1AJ5
| CALPAIN DOMAIN VI APO | Descriptor: | CALPAIN | Authors: | Cygler, M, Grochulski, P, Blanchard, H. | Deposit date: | 1997-05-15 | Release date: | 1998-05-20 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Structure of a calpain Ca(2+)-binding domain reveals a novel EF-hand and Ca(2+)-induced conformational changes. Nat.Struct.Biol., 4, 1997
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1DVI
| CALPAIN DOMAIN VI WITH CALCIUM BOUND | Descriptor: | CALCIUM ION, CALPAIN | Authors: | Cygler, M, Blanchard, H, Grochulski, P. | Deposit date: | 1997-05-15 | Release date: | 1998-05-27 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Structure of a calpain Ca(2+)-binding domain reveals a novel EF-hand and Ca(2+)-induced conformational changes. Nat.Struct.Biol., 4, 1997
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4Z16
| Crystal Structure of the Jak3 Kinase Domain Covalently Bound to N-(3-(((5-chloro-2-((2-methoxy-4-(4-methylpiperazin-1-yl)phenyl)amino)pyrimidin-4-yl)amino)methyl)phenyl)acrylamide | Descriptor: | N-(3-{[(5-chloro-2-{[2-methoxy-4-(4-methylpiperazin-1-yl)phenyl]amino}pyrimidin-4-yl)amino]methyl}phenyl)prop-2-enamide, Tyrosine-protein kinase JAK3 | Authors: | McNally, R, Tan, L, Gray, N.S, Eck, M.J. | Deposit date: | 2015-03-26 | Release date: | 2016-02-10 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (2.9 Å) | Cite: | Development of Selective Covalent Janus Kinase 3 Inhibitors. J.Med.Chem., 58, 2015
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