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2I3W
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BU of 2i3w by Molmil
Measurement of conformational changes accompanying desensitization in an ionotropic glutamate receptor: Structure of S729C mutant
Descriptor: GLUTAMATE RECEPTOR SUBUNIT 2, GLUTAMIC ACID
Authors:Armstrong, N, Jasti, J, Beich-Frandsen, M, Gouaux, E.
Deposit date:2006-08-21
Release date:2006-10-17
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Measurement of Conformational Changes accompanying Desensitization in an Ionotropic Glutamate Receptor.
Cell(Cambridge,Mass.), 127, 2006
2I3V
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BU of 2i3v by Molmil
Measurement of conformational changes accompanying desensitization in an ionotropic glutamate receptor: Structure of G725C mutant
Descriptor: GLUTAMIC ACID, Glutamate receptor 2, ZINC ION
Authors:Armstrong, N, Jasti, J, Beich-Frandsen, M, Gouaux, E.
Deposit date:2006-08-21
Release date:2006-10-17
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Measurement of Conformational Changes accompanying Desensitization in an Ionotropic Glutamate Receptor.
Cell(Cambridge,Mass.), 127, 2006
1P1W
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BU of 1p1w by Molmil
Crystal structure of the GluR2 ligand-binding core (S1S2J) with the L483Y and L650T mutations and in complex with AMPA
Descriptor: (S)-ALPHA-AMINO-3-HYDROXY-5-METHYL-4-ISOXAZOLEPROPIONIC ACID, Glutamate receptor 2 precursor, SULFATE ION
Authors:Armstrong, N, Mayer, M.L, Gouaux, E.
Deposit date:2003-04-14
Release date:2003-06-10
Last modified:2021-10-27
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Tuning activation of the AMPA-sensitive GluR2 ion channel by genetic adjustment of agonist-induced conformational changes.
Proc.Natl.Acad.Sci.USA, 100, 2003
1P1Q
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BU of 1p1q by Molmil
Crystal structure of the GluR2 ligand binding core (S1S2J) L650T mutant in complex with AMPA
Descriptor: (S)-ALPHA-AMINO-3-HYDROXY-5-METHYL-4-ISOXAZOLEPROPIONIC ACID, Glutamate receptor 2, ZINC ION
Authors:Armstrong, N, Mayer, M.L, Gouaux, E.
Deposit date:2003-04-13
Release date:2003-06-10
Last modified:2021-10-27
Method:X-RAY DIFFRACTION (2 Å)
Cite:Tuning activation of the AMPA-sensitive GluR2 ion channel by genetic adjustment of agonist-induced conformational changes.
Proc.Natl.Acad.Sci.USA, 100, 2003
1P1U
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BU of 1p1u by Molmil
Crystal structure of the GluR2 ligand-binding core (S1S2J) L650T mutant in complex with AMPA (ammonium sulfate crystal form)
Descriptor: (S)-ALPHA-AMINO-3-HYDROXY-5-METHYL-4-ISOXAZOLEPROPIONIC ACID, Glutamate receptor 2, SULFATE ION
Authors:Armstrong, N, Mayer, M.L, Gouaux, E.
Deposit date:2003-04-14
Release date:2003-06-10
Last modified:2021-10-27
Method:X-RAY DIFFRACTION (2 Å)
Cite:Tuning activation of the AMPA-sensitive GluR2 ion channel by genetic adjustment of agonist-induced conformational changes.
Proc.Natl.Acad.Sci.USA, 100, 2003
1P1O
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BU of 1p1o by Molmil
Crystal structure of the GluR2 ligand-binding core (S1S2J) mutant L650T in complex with quisqualate
Descriptor: (S)-2-AMINO-3-(3,5-DIOXO-[1,2,4]OXADIAZOLIDIN-2-YL)-PROPIONIC ACID, Glutamate receptor 2, SULFATE ION
Authors:Armstrong, N, Mayer, M.L, Gouaux, E.
Deposit date:2003-04-13
Release date:2003-06-10
Last modified:2021-10-27
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Tuning activation of the AMPA-sensitive GluR2 ion channel by genetic adjustment of agonist-induced conformational changes.
Proc.Natl.Acad.Sci.USA, 100, 2003
1P1N
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BU of 1p1n by Molmil
GluR2 Ligand Binding Core (S1S2J) Mutant L650T in Complex with Kainate
Descriptor: 3-(CARBOXYMETHYL)-4-ISOPROPENYLPROLINE, Glutamate receptor 2
Authors:Armstrong, N, Mayer, M.L, Gouaux, E.
Deposit date:2003-04-13
Release date:2003-06-10
Last modified:2021-10-27
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Tuning activation of the AMPA-sensitive GluR2 ion channel by genetic adjustment of agonist-induced conformational changes.
Proc.Natl.Acad.Sci.USA, 100, 2003
1FTJ
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BU of 1ftj by Molmil
CRYSTAL STRUCTURE OF THE GLUR2 LIGAND BINDING CORE (S1S2J) IN COMPLEX WITH GLUTAMATE AT 1.9 RESOLUTION
Descriptor: GLUTAMATE RECEPTOR SUBUNIT 2, GLUTAMIC ACID, ZINC ION
Authors:Armstrong, N, Gouaux, E.
Deposit date:2000-09-12
Release date:2000-11-01
Last modified:2018-01-31
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Mechanisms for activation and antagonism of an AMPA-sensitive glutamate receptor: crystal structures of the GluR2 ligand binding core.
Neuron, 28, 2000
1FW0
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BU of 1fw0 by Molmil
CRYSTAL STRUCTURE OF THE GLUR2 LIGAND BINDING CORE (S1S2J) IN COMPLEX WITH KAINATE AT 2.0 A RESOLUTION
Descriptor: 3-(CARBOXYMETHYL)-4-ISOPROPENYLPROLINE, GLUTAMATE RECEPTOR SUBUNIT 2
Authors:Armstrong, N, Gouaux, E.
Deposit date:2000-09-20
Release date:2000-11-15
Last modified:2017-08-02
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Mechanisms for activation and antagonism of an AMPA-sensitive glutamate receptor: crystal structures of the GluR2 ligand binding core.
Neuron, 28, 2000
1FTO
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BU of 1fto by Molmil
CRYSTAL STRUCTURE OF THE GLUR2 LIGAND BINDING CORE (S1S2J) IN THE APO STATE AT 2.0 A RESOLUTION
Descriptor: GLUTAMATE RECEPTOR SUBUNIT 2
Authors:Armstrong, N, Gouaux, E.
Deposit date:2000-09-12
Release date:2000-11-01
Last modified:2017-08-02
Method:X-RAY DIFFRACTION (2 Å)
Cite:Mechanisms for activation and antagonism of an AMPA-sensitive glutamate receptor: crystal structures of the GluR2 ligand binding core.
Neuron, 28, 2000
1FTL
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BU of 1ftl by Molmil
CRYSTAL STRUCTURE OF THE GLUR2 LIGAND BINDING CORE (S1S2J) IN COMPLEX WITH THE ANTAGONIST DNQX AT 1.8 A RESOLUTION
Descriptor: 6,7-DINITROQUINOXALINE-2,3-DIONE, GLUTAMATE RECEPTOR SUBUNIT 2, SULFATE ION
Authors:Armstrong, N, Gouaux, E.
Deposit date:2000-09-12
Release date:2000-11-01
Last modified:2017-08-02
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Mechanisms for activation and antagonism of an AMPA-sensitive glutamate receptor: crystal structures of the GluR2 ligand binding core.
Neuron, 28, 2000
1GR2
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BU of 1gr2 by Molmil
STRUCTURE OF A GLUTAMATE RECEPTOR LIGAND BINDING CORE (GLUR2) COMPLEXED WITH KAINATE
Descriptor: 3-(CARBOXYMETHYL)-4-ISOPROPENYLPROLINE, PROTEIN (GLUTAMATE RECEPTOR 2)
Authors:Armstrong, N, Sun, Y, Chen, G.Q, Gouaux, E.
Deposit date:1998-09-17
Release date:1998-12-09
Last modified:2017-08-16
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structure of a glutamate-receptor ligand-binding core in complex with kainate.
Nature, 395, 1998
1FTK
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BU of 1ftk by Molmil
CRYSTAL STRUCTURE OF THE GLUR2 LIGAND BINDING CORE (S1S2I) IN COMPLEX WITH KAINATE AT 1.6 A RESOLUTION
Descriptor: 3-(CARBOXYMETHYL)-4-ISOPROPENYLPROLINE, GLUTAMATE RECEPTOR SUBUNIT 2
Authors:Gouaux, E, Armstrong, N.
Deposit date:2000-09-12
Release date:2000-11-01
Last modified:2017-08-02
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Mechanisms for activation and antagonism of an AMPA-sensitive glutamate receptor: crystal structures of the GluR2 ligand binding core.
Neuron, 28, 2000
1FTM
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BU of 1ftm by Molmil
CRYSTAL STRUCTURE OF THE GLUR2 LIGAND BINDING CORE (S1S2J) IN COMPLEX WITH AMPA AT 1.7 RESOLUTION
Descriptor: (S)-ALPHA-AMINO-3-HYDROXY-5-METHYL-4-ISOXAZOLEPROPIONIC ACID, GLUTAMATE RECEPTOR SUBUNIT 2, ZINC ION
Authors:Gouaux, E, Armstrong, N.
Deposit date:2000-09-12
Release date:2000-11-01
Last modified:2017-08-02
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Mechanisms for activation and antagonism of an AMPA-sensitive glutamate receptor: crystal structures of the GluR2 ligand binding core.
Neuron, 28, 2000
1LB8
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BU of 1lb8 by Molmil
Crystal structure of the Non-desensitizing GluR2 ligand binding core mutant (S1S2J-L483Y) in complex with AMPA at 2.3 resolution
Descriptor: (S)-ALPHA-AMINO-3-HYDROXY-5-METHYL-4-ISOXAZOLEPROPIONIC ACID, Glutamate receptor 2
Authors:Sun, Y, Olson, R, Horning, M, Armstrong, N, Mayer, M, Gouaux, E.
Deposit date:2002-04-02
Release date:2002-06-05
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Mechanism of glutamate receptor desensitization.
Nature, 417, 2002
1LB9
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BU of 1lb9 by Molmil
Crystal structure of the Non-desensitizing GluR2 ligand binding core mutant (S1S2J-L483Y) in complex with antagonist DNQX at 2.3 A resolution
Descriptor: 6,7-DINITROQUINOXALINE-2,3-DIONE, Glutamate receptor 2, SULFATE ION
Authors:Sun, Y, Olson, R, Horning, M, Armstrong, N, Mayer, M, Gouaux, E.
Deposit date:2002-04-02
Release date:2002-06-05
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Mechanism of glutamate receptor desensitization.
Nature, 417, 2002
1LBB
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BU of 1lbb by Molmil
Crystal structure of the GluR2 ligand binding domain mutant (S1S2J-N754D) in complex with kainate at 2.1 A resolution
Descriptor: 3-(CARBOXYMETHYL)-4-ISOPROPENYLPROLINE, Glutamine receptor 2
Authors:Sun, Y, Olson, R, Horning, M, Armstrong, N, Mayer, M, Gouaux, E.
Deposit date:2002-04-02
Release date:2002-06-05
Last modified:2021-10-27
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Mechanism of glutamate receptor desensitization.
Nature, 417, 2002
1LBC
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BU of 1lbc by Molmil
Crystal structure of GluR2 ligand binding core (S1S2J-N775S) in complex with cyclothiazide (CTZ) as well as glutamate at 1.8 A resolution
Descriptor: CYCLOTHIAZIDE, GLUTAMIC ACID, Glutamine Receptor 2, ...
Authors:Sun, Y, Olson, R, Horning, M, Armstrong, N, Mayer, M, Gouaux, E.
Deposit date:2002-04-02
Release date:2002-05-29
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Mechanism of glutamate receptor desensitization.
Nature, 417, 2002
1N0T
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BU of 1n0t by Molmil
X-ray structure of the GluR2 ligand-binding core (S1S2J) in complex with the antagonist (S)-ATPO at 2.1 A resolution.
Descriptor: (S)-2-AMINO-3-(5-TERT-BUTYL-3-(PHOSPHONOMETHOXY)-4-ISOXAZOLYL)PROPIONIC ACID, ACETATE ION, Glutamate receptor 2, ...
Authors:Hogner, A, Greenwood, J.R, Liljefors, T, Lunn, M.-L, Egebjerg, J, Larsen, I.K, Gouaux, E, Kastrup, J.S.
Deposit date:2002-10-15
Release date:2003-03-04
Last modified:2017-08-16
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Competitive antagonism of AMPA receptors by ligands of different classes: crystal structure of ATPO bound to the GluR2 ligand-binding core, in comparison with DNQX.
J.Med.Chem., 46, 2003
3H6W
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BU of 3h6w by Molmil
Crystal structure of the iGluR2 ligand-binding core (S1S2J-N754S) in complex with glutamate and NS5217 at 1.50 A resolution
Descriptor: (3R)-3-cyclopentyl-6-methyl-7-[(4-methylpiperazin-1-yl)sulfonyl]-3,4-dihydro-2H-1,2-benzothiazine 1,1-dioxide, DIMETHYL SULFOXIDE, GLUTAMIC ACID, ...
Authors:Hald, H, Gajhede, M, Kastrup, J.S.
Deposit date:2009-04-24
Release date:2009-07-28
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (1.49 Å)
Cite:Distinct structural features of cyclothiazide are responsible for effects on peak current amplitude and desensitization kinetics at iGluR2.
J.Mol.Biol., 391, 2009
5VRK
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BU of 5vrk by Molmil
Crystal structure of SsoPox AsA6 mutant (F46L-C258A-W263M-I280T) - open form
Descriptor: 1,2-ETHANEDIOL, Aryldialkylphosphatase, COBALT (II) ION, ...
Authors:Hiblot, J, Gotthard, G, Jacquet, P, Daude, D, Bergonzi, C, Chabriere, E, Elias, M.
Deposit date:2017-05-10
Release date:2018-01-10
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:Rational engineering of a native hyperthermostable lactonase into a broad spectrum phosphotriesterase.
Sci Rep, 7, 2017
5W3Z
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BU of 5w3z by Molmil
Crystal structure of SsoPox AsC6 mutant (L72I-Y99F-I122L-L228M-F229S-W263L)
Descriptor: 1,2-ETHANEDIOL, Aryldialkylphosphatase, COBALT (II) ION, ...
Authors:Hiblot, J, Gotthard, G, Jacquet, P, Daude, D, Bergonzi, C, Chabriere, E, Elias, M.
Deposit date:2017-06-08
Release date:2018-01-10
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (2.55 Å)
Cite:Rational engineering of a native hyperthermostable lactonase into a broad spectrum phosphotriesterase.
Sci Rep, 7, 2017
5W3W
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BU of 5w3w by Molmil
Crystal structure of SsoPox AsD6 mutant (V27A-Y97W-L228M-W263M) - open form
Descriptor: 1,2-ETHANEDIOL, Aryldialkylphosphatase, COBALT (II) ION, ...
Authors:Hiblot, J, Gotthard, G, Jacquet, P, Daude, D, Bergonzi, C, Chabriere, E, Elias, M.
Deposit date:2017-06-08
Release date:2018-01-10
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (2.95 Å)
Cite:Rational engineering of a native hyperthermostable lactonase into a broad spectrum phosphotriesterase.
Sci Rep, 7, 2017
5VSA
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BU of 5vsa by Molmil
Crystal structure of SsoPox AsA1 mutant (C258L-I261F-W263A)
Descriptor: Aryldialkylphosphatase, COBALT (II) ION, FE (II) ION, ...
Authors:Hiblot, J, Gotthard, G, Jacquet, P, Daude, D, Bergonzi, C, Chabriere, E, Elias, M.
Deposit date:2017-05-11
Release date:2018-01-10
Last modified:2021-08-18
Method:X-RAY DIFFRACTION (2 Å)
Cite:Rational engineering of a native hyperthermostable lactonase into a broad spectrum phosphotriesterase.
Sci Rep, 7, 2017
5W3U
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BU of 5w3u by Molmil
Crystal structure of SsoPox AsB5 mutant (V27A-I76T-Y97W-Y99F-L130P-L226V)
Descriptor: 1,2-ETHANEDIOL, Aryldialkylphosphatase, COBALT (II) ION, ...
Authors:Hiblot, J, Gotthard, G, Jacquet, P, Daude, D, Bergonzi, C, Chabriere, E, Elias, M.
Deposit date:2017-06-08
Release date:2017-12-20
Last modified:2021-08-18
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Rational engineering of a native hyperthermostable lactonase into a broad spectrum phosphotriesterase.
Sci Rep, 7, 2017

 

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