Loading
PDBj
MenuPDBj@FacebookPDBj@TwitterPDBj@YouTubewwPDB FoundationwwPDB
RCSB PDBPDBeBMRBAdv. SearchSearch help
Search by PDB author
2G12
DownloadVisualize
BU of 2g12 by Molmil
Photolyzed CO L29F Myoglobin: 316ns
Descriptor: CARBON MONOXIDE, Myoglobin, PROTOPORPHYRIN IX CONTAINING FE, ...
Authors:Aranda, R, Levin, E.J, Schotte, F, Anfinrud, P.A, Phillips Jr, G.N.
Deposit date:2006-02-13
Release date:2006-07-04
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Time-dependent atomic coordinates for the dissociation of carbon monoxide from myoglobin.
ACTA CRYSTALLOGR.,SECT.D, 62, 2006
2G11
DownloadVisualize
BU of 2g11 by Molmil
Photolyzed CO L29F Myoglobin: 31.6ns
Descriptor: CARBON MONOXIDE, Myoglobin, PROTOPORPHYRIN IX CONTAINING FE, ...
Authors:Aranda, R, Levin, E.J, Schotte, F, Anfinrud, P.A, Phillips Jr, G.N.
Deposit date:2006-02-13
Release date:2006-07-04
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Time-dependent atomic coordinates for the dissociation of carbon monoxide from myoglobin.
ACTA CRYSTALLOGR.,SECT.D, 62, 2006
2G0R
DownloadVisualize
BU of 2g0r by Molmil
Unphotolyzed CO-bound L29F Myoglobin
Descriptor: CARBON MONOXIDE, Myoglobin, PROTOPORPHYRIN IX CONTAINING FE, ...
Authors:Aranda, R, Levin, E.J, Schotte, F, Anfinrud, P.A, Phillips Jr, G.N.
Deposit date:2006-02-13
Release date:2006-07-04
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Time-dependent atomic coordinates for the dissociation of carbon monoxide from myoglobin.
Acta Crystallogr.,Sect.D, 62, 2006
2G0S
DownloadVisualize
BU of 2g0s by Molmil
Unphotolyzed CO-bound L29F Myoglobin, crystal 2
Descriptor: CARBON MONOXIDE, Myoglobin, PROTOPORPHYRIN IX CONTAINING FE, ...
Authors:Aranda, R, Levin, E.J, Schotte, F, Anfinrud, P.A, Phillips Jr, G.N.
Deposit date:2006-02-13
Release date:2006-07-04
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Time-dependent atomic coordinates for the dissociation of carbon monoxide from myoglobin.
Acta Crystallogr.,Sect.D, 62, 2006
2G0Z
DownloadVisualize
BU of 2g0z by Molmil
Photolyzed CO L29F Myoglobin: 1ns
Descriptor: CARBON MONOXIDE, Myoglobin, PROTOPORPHYRIN IX CONTAINING FE, ...
Authors:Aranda, R, Levin, E.J, Schotte, F, Anfinrud, P.A, Phillips Jr, G.N.
Deposit date:2006-02-13
Release date:2006-07-04
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Time-dependent atomic coordinates for the dissociation of carbon monoxide from myoglobin.
Acta Crystallogr.,Sect.D, 62, 2006
2G0V
DownloadVisualize
BU of 2g0v by Molmil
Photolyzed CO L29F Myoglobin: 100ps
Descriptor: CARBON MONOXIDE, Myoglobin, PROTOPORPHYRIN IX CONTAINING FE, ...
Authors:Aranda, R, Levin, E.J, Schotte, F, Anfinrud, P.A, Phillips Jr, G.N.
Deposit date:2006-02-13
Release date:2006-07-04
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Time-dependent atomic coordinates for the dissociation of carbon monoxide from myoglobin.
Acta Crystallogr.,Sect.D, 62, 2006
2G0X
DownloadVisualize
BU of 2g0x by Molmil
Photolyzed CO L29F Myoglobin: 316ps
Descriptor: CARBON MONOXIDE, Myoglobin, PROTOPORPHYRIN IX CONTAINING FE, ...
Authors:Aranda, R, Levin, E.J, Schotte, F, Anfinrud, P.A, Phillips Jr, G.N.
Deposit date:2006-02-13
Release date:2006-07-04
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Time-dependent atomic coordinates for the dissociation of carbon monoxide from myoglobin.
Acta Crystallogr.,Sect.D, 62, 2006
2G14
DownloadVisualize
BU of 2g14 by Molmil
Photolyzed CO L29F Myoglobin: 3.16us
Descriptor: CARBON MONOXIDE, Myoglobin, PROTOPORPHYRIN IX CONTAINING FE, ...
Authors:Aranda, R, Levin, E.J, Schotte, F, Anfinrud, P.A, Phillips Jr, G.N.
Deposit date:2006-02-13
Release date:2006-07-04
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Time-dependent atomic coordinates for the dissociation of carbon monoxide from myoglobin.
ACTA CRYSTALLOGR.,SECT.D, 62, 2006
2G10
DownloadVisualize
BU of 2g10 by Molmil
Photolyzed CO L29F Myoglobin: 3.16ns
Descriptor: CARBON MONOXIDE, Myoglobin, PROTOPORPHYRIN IX CONTAINING FE, ...
Authors:Aranda, R, Levin, E.J, Schotte, F, Anfinrud, P.A, Phillips Jr, G.N.
Deposit date:2006-02-13
Release date:2006-07-04
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Time-dependent atomic coordinates for the dissociation of carbon monoxide from myoglobin.
Acta Crystallogr.,Sect.D, 62, 2006
3BJ1
DownloadVisualize
BU of 3bj1 by Molmil
met-Perch Hemoglobin at pH 5.7
Descriptor: ACETYL GROUP, PROTOPORPHYRIN IX CONTAINING FE, hemoglobin alpha, ...
Authors:Aranda IV, R, Cai, H, Levin, E.J, Richards, M.P, Phillips Jr, G.N.
Deposit date:2007-12-02
Release date:2008-09-02
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structural analysis of fish versus mammalian hemoglobins: Effect of the heme pocket environment on autooxidation and hemin loss.
Proteins, 75, 2008
3BJ2
DownloadVisualize
BU of 3bj2 by Molmil
met-Perch Hemoglobin at pH 6.3
Descriptor: ACETYL GROUP, PROTOPORPHYRIN IX CONTAINING FE, hemoglobin alpha, ...
Authors:Aranda IV, R, Cai, H, Levin, E.J, Richards, M.P, Phillips Jr, G.N.
Deposit date:2007-12-02
Release date:2008-09-02
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural analysis of fish versus mammalian hemoglobins: Effect of the heme pocket environment on autooxidation and hemin loss.
Proteins, 75, 2008
3BJ3
DownloadVisualize
BU of 3bj3 by Molmil
met-Perch hemoglobin at pH 8.0
Descriptor: ACETYL GROUP, PROTOPORPHYRIN IX CONTAINING FE, hemoglobin alpha, ...
Authors:Aranda IV, R, Cai, H, Levin, E.J, Richards, M.P, Phillips Jr, G.N.
Deposit date:2007-12-02
Release date:2008-09-02
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structural analysis of fish versus mammalian hemoglobins: Effect of the heme pocket environment on autooxidation and hemin loss.
Proteins, 75, 2008
2R1H
DownloadVisualize
BU of 2r1h by Molmil
met-Trout IV hemoglobin at pH 6.3
Descriptor: 1,2-ETHANEDIOL, Hemoglobin subunit alpha-4, Hemoglobin subunit beta-4, ...
Authors:Aranda IV, R, Worley, C.E, Richards, M.P, Phillips Jr, G.N.
Deposit date:2007-08-22
Release date:2008-09-02
Last modified:2013-01-30
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structural analysis of fish versus mammalian hemoglobins: Effect of the heme pocket environment on autooxidation and hemin loss.
Proteins, 75, 2008
2QSS
DownloadVisualize
BU of 2qss by Molmil
Bovine hemoglobin at pH 6.3
Descriptor: CARBON MONOXIDE, Hemoglobin subunit alpha, Hemoglobin subunit beta, ...
Authors:Aranda IV, R, Richards, M.P, Phillips Jr, G.N.
Deposit date:2007-07-31
Release date:2008-09-02
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Structural analysis of fish versus mammalian hemoglobins: Effect of the heme pocket environment on autooxidation and hemin loss.
Proteins, 75, 2008
2QSP
DownloadVisualize
BU of 2qsp by Molmil
Bovine Hemoglobin at pH 5.7
Descriptor: Hemoglobin subunit alpha, Hemoglobin subunit beta, PROTOPORPHYRIN IX CONTAINING FE
Authors:Aranda IV, R, Richards, M.P, Phillips Jr, G.N.
Deposit date:2007-07-31
Release date:2008-09-02
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Structural analysis of fish versus mammalian hemoglobins: Effect of the heme pocket environment on autooxidation and hemin loss.
Proteins, 75, 2008
7UOH
DownloadVisualize
BU of 7uoh by Molmil
PRMT5/MEP50 crystal structure with MTA and an achiral, class 1, non-atropisomeric inhibitor bound
Descriptor: (2M)-2-[(4M)-4-{4-(aminomethyl)-1-oxo-8-[(2R)-oxolan-2-yl]-1,2-dihydrophthalazin-6-yl}-1-methyl-1H-pyrazol-5-yl]-1-benzothiophene-3-carbonitrile, 5'-DEOXY-5'-METHYLTHIOADENOSINE, Methylosome protein 50, ...
Authors:Gunn, R.J, Thomas, N.C, Lawson, J.D, Ivetac, A, Kulyk, S, Smith, C.R, Marx, M.A.
Deposit date:2022-04-12
Release date:2022-08-17
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Design and evaluation of achiral, non-atropisomeric 4-(aminomethyl)phthalazin-1(2H)-one derivatives as novel PRMT5/MTA inhibitors.
Bioorg.Med.Chem., 71, 2022
1JW8
DownloadVisualize
BU of 1jw8 by Molmil
1.3 ANGSTROM RESOLUTION CRYSTAL STRUCTURE OF P6 FORM OF MYOGLOBIN
Descriptor: CARBON MONOXIDE, MYOGLOBIN, PROTOPORPHYRIN IX CONTAINING FE, ...
Authors:Phillips Jr, G.N.
Deposit date:2001-09-03
Release date:2001-10-10
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (1.3 Å)
Cite:Sampling of the native conformational ensemble of myoglobin via structures in different crystalline environments.
Proteins, 70, 2008
8V8I
DownloadVisualize
BU of 8v8i by Molmil
PI3Ka H1047R co-crystal structure with inhibitor in cryptic pocket (compound 5).
Descriptor: (2S)-N~1~-[(4P)-2-tert-butyl-4'-methyl[4,5'-bi-1,3-thiazol]-2'-yl]pyrrolidine-1,2-dicarboxamide, CHLORIDE ION, N-{(3S)-3-(2-methylphenyl)-6-[(oxetan-3-yl)amino]-1-oxo-2,3-dihydro-1H-isoindol-4-yl}-1-benzothiophene-3-carboxamide, ...
Authors:Gunn, R.J, Lawson, J.D.
Deposit date:2023-12-05
Release date:2024-03-20
Last modified:2024-03-27
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Discovery of Pyridopyrimidinones that Selectively Inhibit the H1047R PI3K alpha Mutant Protein.
J.Med.Chem., 2024
8V8U
DownloadVisualize
BU of 8v8u by Molmil
PI3Ka H1047R co-crystal structure with inhibitor in cryptic pocket near H1047R (compound 12).
Descriptor: (2S)-N~1~-{4-methyl-5-[2-(1,1,1-trifluoro-2-methylpropan-2-yl)pyridin-4-yl]-1,3-thiazol-2-yl}pyrrolidine-1,2-dicarboxamide, (3S)-9-[(1R)-1-(2-carboxyanilino)ethyl]-3-cyano-7-methyl-4-oxo-2-(piperidin-1-yl)-3,4-dihydropyrido[1,2-a]pyrimidin-5-ium, Phosphatidylinositol 3-kinase regulatory subunit alpha, ...
Authors:Gunn, R.J, Lawson, J.D.
Deposit date:2023-12-06
Release date:2024-03-20
Last modified:2024-03-27
Method:X-RAY DIFFRACTION (2.93 Å)
Cite:Discovery of Pyridopyrimidinones that Selectively Inhibit the H1047R PI3K alpha Mutant Protein.
J.Med.Chem., 2024
8V8V
DownloadVisualize
BU of 8v8v by Molmil
PI3Ka H1047R co-crystal structure with inhibitor in cryptic pocket near H1047R (compound 7).
Descriptor: (2S)-N~1~-{4-methyl-5-[2-(1,1,1-trifluoro-2-methylpropan-2-yl)pyridin-4-yl]-1,3-thiazol-2-yl}pyrrolidine-1,2-dicarboxamide, 2-[[(1~{R})-1-(7-methyl-4-oxidanylidene-2-piperidin-1-yl-3~{H}-pyrido[1,2-a]pyrimidin-9-yl)ethyl]amino]benzoic acid, Phosphatidylinositol 3-kinase regulatory subunit alpha, ...
Authors:Gunn, R.J, Lawson, J.D.
Deposit date:2023-12-06
Release date:2024-03-20
Last modified:2024-03-27
Method:X-RAY DIFFRACTION (2.61 Å)
Cite:Discovery of Pyridopyrimidinones that Selectively Inhibit the H1047R PI3K alpha Mutant Protein.
J.Med.Chem., 2024
8V8J
DownloadVisualize
BU of 8v8j by Molmil
PI3Ka H1047R co-crystal structure with inhibitors in two cryptic pockets (compounds 4 and 5).
Descriptor: (2S)-N~1~-[(4P)-2-tert-butyl-4'-methyl[4,5'-bi-1,3-thiazol]-2'-yl]pyrrolidine-1,2-dicarboxamide, 2-({(1R)-1-[2-(4,4-dimethylpiperidin-1-yl)-3,6-dimethyl-4-oxo-4H-1-benzopyran-8-yl]ethyl}amino)benzoic acid, N-{(3S)-3-(2-methylphenyl)-6-[(oxetan-3-yl)amino]-1-oxo-2,3-dihydro-1H-isoindol-4-yl}-1-benzothiophene-3-carboxamide, ...
Authors:Gunn, R.J, Lawson, J.D.
Deposit date:2023-12-05
Release date:2024-03-20
Last modified:2024-03-27
Method:X-RAY DIFFRACTION (3.35 Å)
Cite:Discovery of Pyridopyrimidinones that Selectively Inhibit the H1047R PI3K alpha Mutant Protein.
J.Med.Chem., 2024
8V8H
DownloadVisualize
BU of 8v8h by Molmil
PI3Ka H1047R co-crystal structure with inhibitor in cryptic pocket near H1047R (compound 4).
Descriptor: (2S)-N~1~-[(4P)-2-tert-butyl-4'-methyl[4,5'-bi-1,3-thiazol]-2'-yl]pyrrolidine-1,2-dicarboxamide, 2-({(1R)-1-[2-(4,4-dimethylpiperidin-1-yl)-3,6-dimethyl-4-oxo-4H-1-benzopyran-8-yl]ethyl}amino)benzoic acid, Phosphatidylinositol 3-kinase regulatory subunit alpha, ...
Authors:Gunn, R.J, Lawson, J.D.
Deposit date:2023-12-05
Release date:2024-03-20
Last modified:2024-03-27
Method:X-RAY DIFFRACTION (3.58 Å)
Cite:Discovery of Pyridopyrimidinones that Selectively Inhibit the H1047R PI3K alpha Mutant Protein.
J.Med.Chem., 2024
1U7S
DownloadVisualize
BU of 1u7s by Molmil
Crystal structure of Native Sperm Whale myoglobin from low ionic strength enviroment (Form 1)
Descriptor: Myoglobin, PROTOPORPHYRIN IX CONTAINING FE
Authors:Zhang, W, Phillips Jr, G.N.
Deposit date:2004-08-04
Release date:2005-07-19
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:Sampling of the native conformational ensemble of myoglobin via structures in different crystalline environments.
Proteins, 70, 2008
1U7R
DownloadVisualize
BU of 1u7r by Molmil
Crystal structure of Native Sperm Whale myoglobin from low ionic strength enviroment (Form2 )
Descriptor: IMIDAZOLE, Myoglobin, PROTOPORPHYRIN IX CONTAINING FE
Authors:Zhang, W, Phillips Jr, G.N.
Deposit date:2004-08-04
Release date:2005-07-19
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (1.15 Å)
Cite:Sampling of the native conformational ensemble of myoglobin via structures in different crystalline environments.
Proteins, 70, 2008
7S1Q
DownloadVisualize
BU of 7s1q by Molmil
PRMT5/MEP50 crystal structure with MTA and a phthalazinone inhibitor bound (Compound 9)
Descriptor: 5'-DEOXY-5'-METHYLTHIOADENOSINE, Methylosome protein 50, Protein arginine N-methyltransferase 5, ...
Authors:Gunn, R.J, Thomas, N.C, Lawson, J.D, Ivetac, A, Smith, C.R, Kulyk, S, Marx, M.A.
Deposit date:2021-09-02
Release date:2022-01-26
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.78 Å)
Cite:Fragment-Based Discovery of MRTX1719, a Synthetic Lethal Inhibitor of the PRMT5•MTA Complex for the Treatment of MTAP -Deleted Cancers.
J.Med.Chem., 65, 2022

 

12>

217705

PDB entries from 2024-03-27

PDB statisticsPDBj update infoContact PDBjnumon