Author results

1J1B
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BINARY COMPLEX STRUCTURE OF HUMAN TAU PROTEIN KINASE I WITH AMPPNP
Descriptor:Glycogen synthase kinase-3 beta, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER
Authors:Aoki, M., Yokota, T., Sugiura, I., Sasaki, C., Hasegawa, T., Okumura, C., Kohno, T., Sugio, S., Matsuzaki, T.
Deposit date:2002-12-03
Release date:2003-12-03
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structural insight into nucleotide recognition in tau-protein kinase I/glycogen synthase kinase 3 beta.
Acta Crystallogr.,Sect.D, 60, 2004
1J1C
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BINARY COMPLEX STRUCTURE OF HUMAN TAU PROTEIN KINASE I WITH ADP
Descriptor:Glycogen synthase kinase-3 beta, MAGNESIUM ION, ADENOSINE-5'-DIPHOSPHATE
Authors:Aoki, M., Yokota, T., Sugiura, I., Sasaki, C., Hasegawa, T., Okumura, C., Kohno, T., Sugio, S., Matsuzaki, T.
Deposit date:2002-12-03
Release date:2003-12-03
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structural insight into nucleotide recognition in tau-protein kinase I/glycogen synthase kinase 3 beta.
Acta Crystallogr.,Sect.D, 60, 2004
5COK
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X-RAY CRYSTAL STRUCTURE OF WILD TYPE HIV-1 PROTEASE IN COMPLEX WITH GRL-0476
Descriptor:HIV-1 protease, (3aS,4S,7aR)-hexahydro-4H-furo[2,3-b]pyran-4-yl [(2S,3R)-3-hydroxy-4-{[(4-methoxyphenyl)sulfonyl](2-methylpropyl)amino}-1-phenylbutan-2-yl]carbamate
Authors:Yedidi, R.S., Hayashi, H., Aoki, M., Das, D., Ghosh, A.K., Mitsuya, H.
Deposit date:2015-07-20
Release date:2016-01-13
Last modified:2017-09-27
Method:X-RAY DIFFRACTION (1.801 Å)
Cite:C-5-Modified Tetrahydropyrano-Tetrahydofuran-Derived Protease Inhibitors (PIs) Exert Potent Inhibition of the Replication of HIV-1 Variants Highly Resistant to Various PIs, including Darunavir.
J.Virol., 90, 2015
5CON
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X-RAY CRYSTAL STRUCTURE OF WILD TYPE HIV-1 PROTEASE IN COMPLEX WITH GRL-015
Descriptor:HIV-1 protease, (3R,3aS,4S,7aS)-3-hydroxyhexahydro-4H-furo[2,3-b]pyran-4-yl [(2S,3R)-3-hydroxy-4-{[(4-methoxyphenyl)sulfonyl](2-methylpropyl)amino}-1-phenylbutan-2-yl]carbamate
Authors:Yedidi, R.S., Hayashi, H., Aoki, M., Das, D., Ghosh, A.K., Mitsuya, H.
Deposit date:2015-07-20
Release date:2016-01-13
Last modified:2017-09-27
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:C-5-Modified Tetrahydropyrano-Tetrahydofuran-Derived Protease Inhibitors (PIs) Exert Potent Inhibition of the Replication of HIV-1 Variants Highly Resistant to Various PIs, including Darunavir.
J.Virol., 90, 2015
5COO
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X-RAY CRYSTAL STRUCTURE OF WILD TYPE HIV-1 PROTEASE IN COMPLEX WITH GRL-085
Descriptor:HIV-1 protease, (3R,3aS,4S,7aS)-3-hydroxyhexahydro-4H-furo[2,3-b]pyran-4-yl [(2S,3R)-3-hydroxy-1-(4-methoxyphenyl)-4-{[(4-methoxyphenyl)sulfonyl](2-methylpropyl)amino}butan-2-yl]carbamate
Authors:Yedidi, R.S., Hayashi, H., Aoki, M., Das, D., Ghosh, A.K., Mitsuya, H.
Deposit date:2015-07-20
Release date:2016-01-13
Last modified:2017-09-27
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:C-5-Modified Tetrahydropyrano-Tetrahydofuran-Derived Protease Inhibitors (PIs) Exert Potent Inhibition of the Replication of HIV-1 Variants Highly Resistant to Various PIs, including Darunavir.
J.Virol., 90, 2015
5COP
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X-RAY CRYSTAL STRUCTURE OF WILD TYPE HIV-1 PROTEASE IN COMPLEX WITH GRL-097
Descriptor:HIV-1 protease, (3R,3aS,4S,7aS)-3-hydroxyhexahydro-4H-furo[2,3-b]pyran-4-yl [(2S,3R)-4-{[(4-aminophenyl)sulfonyl](2-methylpropyl)amino}-3-hydroxy-1-(4-methoxyphenyl)butan-2-yl]carbamate
Authors:Yedidi, R.S., Hayashi, H., Aoki, M., Das, D., Ghosh, A.K., Mitsuya, H.
Deposit date:2015-07-20
Release date:2016-01-13
Last modified:2017-09-27
Method:X-RAY DIFFRACTION (2 Å)
Cite:C-5-Modified Tetrahydropyrano-Tetrahydofuran-Derived Protease Inhibitors (PIs) Exert Potent Inhibition of the Replication of HIV-1 Variants Highly Resistant to Various PIs, including Darunavir.
J.Virol., 90, 2015
5TYR
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X-RAY CRYSTAL STRUCTURE OF WILD TYPE HIV-1 PROTEASE IN COMPLEX WITH GRL-121
Descriptor:Protease, (3S,3aR,5R,7aS,8S)-hexahydro-4H-3,5-methanofuro[2,3-b]pyran-8-yl {(2S,3R)-4-[{[2-(cyclopropylamino)-1,3-benzothiazol-6-yl]sulfonyl}(2-methylpropyl)amino]-3-hydroxy-1-phenylbutan-2-yl}carbamate
Authors:Yedidi, R.S., Hayashi, H., Aoki, M., Das, D., Ghosh, A.K., Mitsuya, H.
Deposit date:2016-11-21
Release date:2017-10-18
Last modified:2017-11-01
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:A novel central nervous system-penetrating protease inhibitor overcomes human immunodeficiency virus 1 resistance with unprecedented aM to pM potency.
Elife, 6, 2017
5TYS
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X-RAY CRYSTAL STRUCTURE OF WILD TYPE HIV-1 PROTEASE IN COMPLEX WITH GRL-142
Descriptor:Protease, (3S,3aR,5R,7aS,8S)-hexahydro-4H-3,5-methanofuro[2,3-b]pyran-8-yl [(2S,3R)-4-[{[2-(cyclopropylamino)-1,3-benzothiazol-6-yl]sulfonyl}(2-methylpropyl)amino]-1-(3,5-difluorophenyl)-3-hydroxybutan-2-yl]carbamate
Authors:Yedidi, R.S., Hayashi, H., Aoki, M., Das, D., Ghosh, A.K., Mitsuya, H.
Deposit date:2016-11-21
Release date:2017-10-18
Last modified:2017-11-01
Method:X-RAY DIFFRACTION (2.007 Å)
Cite:A novel central nervous system-penetrating protease inhibitor overcomes human immunodeficiency virus 1 resistance with unprecedented aM to pM potency.
Elife, 6, 2017
1VDY
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NMR STRUCTURE OF THE HYPOTHETICAL ENTH-VHS DOMAIN AT3G16270 FROM ARABIDOPSIS THALIANA
Descriptor:hypothetical protein (RAFL09-17-B18)
Authors:Lopez-Mendez, B., Pantoja-Uceda, D., Tomizawa, T., Koshiba, S., Kigawa, T., Shirouzu, M., Terada, T., Inoue, M., Yabuki, T., Aoki, M., Seki, E., Matsuda, T., Hirota, H., Yoshida, M., Tanaka, A., Osanai, T., Seki, M., Shinozaki, K., Yokoyama, S., Guntert, P., RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:2004-03-25
Release date:2005-05-03
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Solution structure of the hypothetical ENTH-VHS domain AT3G16270 from arabidopsis thaliana
To be Published
1UF4
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CRYSTAL STRUCTURE OF C171A/V236A MUTANT OF N-CARBAMYL-D-AMINO ACID AMIDOHYDROLASE
Descriptor:N-carbamyl-D-amino acid amidohydrolase
Authors:Hashimoto, H., Aoki, M., Shimizu, T., Nakai, T., Morikawa, H., Ikenaka, Y., Takahashi, S., Sato, M.
Deposit date:2003-05-23
Release date:2004-06-08
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:Crystal structure of C171A/V236A Mutant of N-carbamyl-D-amino acid
To be published
1UF5
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CRYSTAL STRUCTURE OF C171A/V236A MUTANT OF N-CARBAMYL-D-AMINO ACID AMIDOHYDROLASE COMPLEXED WITH N-CARBAMYL-D-METHIONINE
Descriptor:N-carbamyl-D-amino acid amidohydrolase, 4-METHYLSULFANYL-2-UREIDO-BUTYRIC ACID, 1,2-ETHANEDIOL
Authors:Hashimoto, H., Aoki, M., Shimizu, T., Nakai, T., Morikawa, H., Ikenaka, Y., Takahashi, S., Sato, M.
Deposit date:2003-05-23
Release date:2004-06-08
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Crystal structure of C171A/V236A mutant of N-carbamyl-D-amino acid amidohydrolase
To be published
1UF7
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CRYSTAL STRUCTURE OF C171A/V236A MUTANT OF N-CARBAMYL-D-AMINO ACID AMIDOHYDROLASE COMPLEXED WITH N-CARBAMYL-D-VALINE
Descriptor:N-carbamyl-D-amino acid amidohydrolase, 3-METHYL-2-UREIDO-BUTYRIC ACID
Authors:Hashimoto, H., Aoki, M., Shimizu, T., Nakai, T., Morikawa, H., Ikenaka, Y., Takahashi, S., Sato, M.
Deposit date:2003-05-26
Release date:2004-06-08
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Crystal structure of C171A/V236A Mutant of N-carbamyl-D-amino acid amidohydrolase
To be published
1UF8
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CRYSTAL STRUCTURE OF C171A/V236A MUTANT OF N-CARBAMYL-D-AMINO ACID AMIDOHYDROLASE COMPLEXED WITH N-CARBAMYL-D-PHENYLALANINE
Descriptor:N-carbamyl-D-amino acid amidohydrolase, D-[(AMINO)CARBONYL]PHENYLALANINE
Authors:Hashimoto, H., Aoki, M., Shimizu, T., Nakai, T., Morikawa, H., Ikenaka, Y., Takahashi, S., Sato, M.
Deposit date:2003-05-26
Release date:2004-06-08
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Crystal structure of C171A/V236A Mutant of N-carbamyl-D-amino acid amidohydrolase
To be published
1UFN
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SOLUTION STRUCTURE OF THE SAND DOMAIN OF THE PUTATIVE NUCLEAR PROTEIN HOMOLOG (5830484A20RIK)
Descriptor:putative nuclear protein homolog 5830484A20Rik
Authors:Tochio, N., Kobayashi, N., Koshiba, S., Kigawa, T., Inoue, M., Shirouzu, M., Terada, T., Yabuki, T., Aoki, M., Seki, E., Matsuda, T., Hirota, H., Yoshida, M., Tanaka, A., Osanai, T., Matsuo, Y., Arakawa, T., Carninci, P., Kawai, J., Hayashizaki, Y., Yokoyama, S., RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:2003-06-02
Release date:2004-06-22
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Solution structure of the SAND domain of the putative nuclear protein homolog (5830484A20Rik)
To be Published
1UFW
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SOLUTION STRUCTURE OF RNP DOMAIN IN SYNAPTOJANIN 2
Descriptor:Synaptojanin 2
Authors:He, F., Muto, Y., Ushikoshi, R., Shirouzu, M., Terada, T., Kigawa, T., Inoue, M., Yabuki, T., Aoki, M., Seki, E., Matsuda, T., Hirota, H., Yoshida, M., Kobayashi, N., Tanaka, A., Osanai, T., Matsuo, Y., Ohara, O., Nagase, T., Kikuno, R., Nakayama, M., Yokoyama, S., RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:2003-06-10
Release date:2003-12-10
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Solution structure of RNP domain in Synaptojanin 2
To be Published
1UFX
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SOLUTION STRUCTURE OF THE THIRD PDZ DOMAIN OF HUMAN KIAA1526 PROTEIN
Descriptor:KIAA1526 protein
Authors:Tochio, N., Kobayashi, N., Koshiba, S., Kigawa, T., Inoue, M., Shirouzu, M., Terada, T., Yabuki, T., Aoki, M., Seki, E., Matsuda, T., Hirota, H., Yoshida, M., Tanaka, A., Osanai, T., Matsuo, Y., Ohara, O., Nagase, T., Kikuno, R., Nakayama, M., Yokoyama, S., RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:2003-06-10
Release date:2003-12-10
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Solution structure of the third PDZ domain of human KIAA1526 protein
To be Published
1UFZ
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SOLUTION STRUCTURE OF HBS1-LIKE DOMAIN IN HYPOTHETICAL PROTEIN BAB28515
Descriptor:Hypothetical protein BAB28515
Authors:He, F., Muto, Y., Hayami, N., Shirouzu, M., Terada, T., Kigawa, T., Inoue, M., Yabuki, T., Aoki, M., Seki, E., Matsuda, T., Hirota, H., Yoshida, M., Kobayashi, N., Tanaka, A., Osanai, T., Matsuo, Y., Hayashizaki, Y., Yokoyama, S., RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:2003-06-11
Release date:2004-08-03
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Solution structure of HBS1-like domain in hypothetical protein BAB28515
To be Published
1UG0
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SOLUTION STRUCTURE OF SURP DOMAIN IN BAB30904
Descriptor:splicing factor 4
Authors:He, F., Muto, Y., Ushikoshi, R., Koshiba, S., Shirouzu, M., Terada, T., Kigawa, T., Inoue, M., Yabuki, T., Aoki, M., Seki, E., Matsuda, T., Hirota, H., Yoshida, M., Kobayashi, N., Tanaka, A., Osanai, T., Matsuo, Y., Hayashizaki, Y., Yokoyama, S., RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:2003-06-11
Release date:2004-08-03
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Solution structure of SURP domain in BAB30904
To be Published
1UG1
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SH3 DOMAIN OF HYPOTHETICAL PROTEIN BAA76854.1
Descriptor:KIAA1010 protein
Authors:Nagata, T., Muto, Y., Kamewari, Y., Shirouzu, M., Terada, T., Kigawa, T., Inoue, M., Yabuki, T., Aoki, M., Seki, E., Matsuda, T., Hirota, H., Yoshida, M., Kobayashi, N., Tanaka, A., Osanai, T., Matsuo, Y., Ohara, O., Nagase, T., Kikuno, R., Nakayama, M., Yokoyama, S., RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:2003-06-11
Release date:2003-12-11
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:NMR structure of SH3 domain of Hypothetical protein BAA76854.1
To be Published
1UG2
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SOLUTION STRUCTURE OF MOUSE HYPOTHETICAL GENE (2610100B20RIK) PRODUCT HOMOLOGOUS TO MYB DNA-BINDING DOMAIN
Descriptor:2610100B20Rik gene product
Authors:Zhao, C., Kigawa, T., Tochio, N., Koshiba, S., Inoue, M., Shirouzu, M., Terada, T., Yabuki, T., Aoki, M., Seki, E., Matsuda, T., Tanaka, A., Osanai, T., Arakawa, T., Carninci, P., Kawai, J., Hayashizaki, Y., Yokoyama, S., RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:2003-06-11
Release date:2004-06-22
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Solution Structure of Mouse Hypothetical Gene (2610100B20Rik) Product Homologous to Myb DNA-binding Domain
To be Published
1UG7
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SOLUTION STRUCTURE OF FOUR HELICAL UP-AND-DOWN BUNDLE DOMAIN OF THE HYPOTHETICAL PROTEIN 2610208M17RIK SIMILAR TO THE PROTEIN FLJ12806
Descriptor:2610208M17Rik protein
Authors:Li, H., Kigawa, T., Tomizawa, T., Koshiba, S., Inoue, M., Shirouzu, M., Terada, M., Yabuki, T., Aoki, M., Seki, E., Matsuda, T., Hirota, H., Yoshida, M., Tanaka, A., Osanai, T., Arakawa, T., Carninci, P., Kawai, J., Hayashizaki, Y., Yokoyama, S., RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:2003-06-13
Release date:2004-08-17
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Solution structure of four helical up-and-down bundle domain of the hypothetical protein 2610208M17Rik similar to the protein FLJ12806
To be Published
1UG8
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NMR STRUCTURE OF THE R3H DOMAIN FROM POLY(A)-SPECIFIC RIBONUCLEASE
Descriptor:Poly(A)-specific Ribonuclease
Authors:Nagata, T., Muto, Y., Hayami, N., Uda, H., Shirouzu, M., Terada, T., Kigawa, T., Inoue, M., Yabuki, T., Aoki, M., Seki, E., Matsuda, T., Hirota, H., Yoshida, M., Kobayashi, N., Tanaka, A., Osanai, T., Matsuo, Y., Arakawa, T., Carninci, P., Kawai, J., Hayashizaki, Y., Yokoyama, S., RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:2003-06-15
Release date:2004-08-17
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:NMR structure of the R3H domain from Poly(A)-specific Ribonuclease
To be Published
1UGJ
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SOLUTION STRUCTURE OF A MURINE HYPOTHETICAL PROTEIN FROM RIKEN CDNA 2310057J16
Descriptor:RIKEN cDNA 2310057J16 protein
Authors:Nagashima, T., Hayashi, F., Shirouzu, M., Terada, T., Kigawa, T., Inoue, M., Yabuki, T., Aoki, M., Seki, E., Matsuda, T., Hirota, H., Yoshida, M., Tanaka, A., Osanai, T., Arakawa, T., Carninci, P., Kawai, J., Hayashizaki, Y., Yokoyama, S., RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:2003-06-16
Release date:2004-08-03
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Solution structure of a murine hypothetical protein from RIKEN cDNA 2310057J16
To be Published
1UGK
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SOLUTION STRUCTURE OF THE FIRST C2 DOMAIN OF SYNAPTOTAGMIN IV FROM HUMAN FETAL BRAIN (KIAA1342)
Descriptor:Synaptotagmin IV
Authors:Nagashima, T., Hayashi, F., Shirouzu, M., Terada, T., Kigawa, T., Inoue, M., Yabuki, T., Aoki, M., Seki, E., Matsuda, T., Hirota, H., Yoshida, M., Tanaka, A., Osanai, T., Matsuo, Y., Ohara, O., Nagase, T., Kikuno, R., Nakayama, M., Yokoyama, S., RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:2003-06-16
Release date:2003-12-16
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Solution structure of the first C2 domain of synaptotagmin IV from human fetal brain (KIAA1342)
To be Published
1UGV
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SOLUTION STRUCTURE OF THE SH3 DOMAIN OF HUMAN OLYGOPHREIN-1 LIKE PROTEIN (KIAA0621)
Descriptor:Olygophrenin-1 like protein
Authors:Inoue, K., Hayashi, F., Shirouzu, M., Terada, T., Kigawa, T., Inoue, M., Yabuki, T., Aoki, M., Seki, E., Matsuda, T., Hirota, H., Yoshida, M., Tanaka, A., Osanai, T., Matsuo, Y., Ohara, O., Nagase, T., Kikuno, R., Nakayama, M., Yokoyama, S., RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:2003-06-20
Release date:2003-12-20
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Solution structure of the SH3 domain of human olygophrein-1 like protein (KIAA0621)
To be Published