Author results

1WAB
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PLATELET-ACTIVATING FACTOR ACETYLHYDROLASE
Descriptor:PLATELET-ACTIVATING FACTOR ACETYLHYDROLASE, ACETATE ION
Authors:Ho, Y.S., Swenson, L., Derewenda, U., Serre, L., Wei, Y., Dauter, Z., Hattori, M., Aoki, J., Arai, H., Adachi, T., Inoue, K., Derewenda, Z.S.
Deposit date:1996-10-30
Release date:1997-11-12
Last modified:2011-11-16
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Brain acetylhydrolase that inactivates platelet-activating factor is a G-protein-like trimer.
Nature, 385, 1997
1JFR
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CRYSTAL STRUCTURE OF THE STREPTOMYCES EXFOLIATUS LIPASE AT 1.9A RESOLUTION: A MODEL FOR A FAMILY OF PLATELET-ACTIVATING FACTOR ACETYLHYDROLASES
Descriptor:LIPASE
Authors:Wei, Y., Derewenda, Z.S.
Deposit date:1997-07-11
Release date:1998-07-15
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structure of a microbial homologue of mammalian platelet-activating factor acetylhydrolases: Streptomyces exfoliatus lipase at 1.9 A resolution.
Structure, 6, 1998
1BWP
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PROBING THE SUBSTRATE SPECIFICITY OF THE INTRACELLULAR BRAIN PLATELET-ACTIVATING FACTOR ACETYLHYDROLASE
Descriptor:PLATELET-ACTIVATING FACTOR ACETYLHYDROLASE
Authors:Ho, Y.S., Sheffield, P.J., Masuyama, J., Arai, H., Li, J., Aoki, J., Inoue, K., Derewenda, U., Derewenda, Z.
Deposit date:1998-09-27
Release date:1999-05-18
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Probing the Substrate Specificity of the Intracellular Brain Platelet-Activating Factor Acetylhydrolase
Protein Eng., 12, 1999
1BWQ
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PROBING THE SUBSTRATE SPECIFICITY OF THE INTRACELLULAR BRAIN PLATELET-ACTIVATING FACTOR ACETYLHYDROLASE
Descriptor:PLATELET-ACTIVATING FACTOR ACETYLHYDROLASE
Authors:Ho, Y.S., Sheffield, P.J., Masuyama, J., Arai, H., Li, J., Aoki, J., Inoue, K., Derewenda, U., Derewenda, Z.
Deposit date:1998-09-27
Release date:1999-05-18
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Probing the Substrate Specificity of the Intracellular Brain Platelet-Activating Factor Acetylhydrolase
Protein Eng., 12, 1999
1BWR
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PROBING THE SUBSTRATE SPECIFICITY OF THE INTRACELLULAR BRAIN PLATELET-ACTIVATING FACTOR ACETYLHYDROLASE
Descriptor:PLATELET-ACTIVATING FACTOR ACETYLHYDROLASE
Authors:Ho, Y.S., Sheffield, P.J., Masuyama, J., Arai, H., Li, J., Aoki, J., Inoue, K., Derewenda, U., Derewenda, Z.
Deposit date:1998-09-27
Release date:1999-05-18
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Probing the Substrate Specificity of the Intracellular Brain Platelet-Activating Factor Acetylhydrolase
Protein Eng., 12, 1999
1ES9
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X-RAY CRYSTAL STRUCTURE OF R22K MUTANT OF THE MAMMALIAN BRAIN PLATELET-ACTIVATING FACTOR ACETYLHYDROLASES (PAF-AH)
Descriptor:PLATELET-ACTIVATING FACTOR ACETYLHYDROLASE IB GAMMA SUBUNIT
Authors:McMullen, T.W.P., Li, J., Sheffield, P.J., Aoki, J., Martin, T.W., Arai, H., Inoue, K., Derewenda, Z.S.
Deposit date:2000-04-07
Release date:2000-05-31
Last modified:2018-01-31
Method:X-RAY DIFFRACTION (1.3 Å)
Cite:The functional implications of the dimerization of the catalytic subunits of the mammalian brain platelet-activating factor acetylhydrolase (Ib).
Protein Eng., 13, 2000
1FXW
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CRYSTAL STRUCTURE OF THE RECOMBINANT ALPHA1/ALPHA2 CATALYTIC HETERODIMER OF BOVINE BRAIN PLATELET-ACTIVATING FACTOR ACETYLHYDROLASE IB.
Descriptor:PLATELET-ACTIVATING FACTOR ACETYLHYDROLASE IB GAMMA SUBUNIT, PLATELET-ACTIVATING FACTOR ACETYLHYDROLASE IB BETA SUBUNIT, CALCIUM ION
Authors:Derewenda, Z., Li, J.
Deposit date:2000-09-27
Release date:2001-12-12
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Preparation and crystal structure of the recombinant alpha(1)/alpha(2) catalytic heterodimer of bovine brain platelet-activating factor acetylhydrolase Ib.
Protein Eng., 14, 2001
3DT6
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CRYSTAL STRUCTURE OF BOVIN BRAIN PLATELET ACTIVATING FACTOR ACETYLHYDROLASE COVALENTLY INHIBITED BY PARAOXON
Descriptor:Brain Platelet-activating factor acetylhydrolase IB subunit alpha, DIETHYL PHOSPHONATE
Authors:Epstein, T.M., Samanta, U., Bahnson, B.J.
Deposit date:2008-07-14
Release date:2009-05-12
Last modified:2017-10-25
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Crystal structures of brain group-VIII phospholipase A2 in nonaged complexes with the organophosphorus nerve agents soman and sarin.
Biochemistry, 48, 2009
3DT8
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CRYSTAL STRUCTURE OF BOVIN BRAIN PLATELET ACTIVATING FACTOR ACETYLHYDROLASE COVALENTLY INHIBITED BY SARIN
Descriptor:Brain Platelet-activating factor acetylhydrolase IB subunit alpha
Authors:Epstein, T.M., Samanta, U., Bahnson, B.J.
Deposit date:2008-07-14
Release date:2009-05-12
Last modified:2017-10-25
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Crystal structures of brain group-VIII phospholipase A2 in nonaged complexes with the organophosphorus nerve agents soman and sarin.
Biochemistry, 48, 2009
3DT9
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CRYSTAL STRUCTURE OF BOVIN BRAIN PLATELET ACTIVATING FACTOR ACETYLHYDROLASE COVALENTLY INHIBITED BY SOMAN
Descriptor:Brain Platelet-activating factor acetylhydrolase IB subunit alpha, (1R)-1,2,2-TRIMETHYLPROPYL (R)-METHYLPHOSPHINATE
Authors:Epstein, T.M., Samanta, U., Bahnson, B.J.
Deposit date:2008-07-14
Release date:2009-05-12
Last modified:2017-10-25
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Crystal structures of brain group-VIII phospholipase A2 in nonaged complexes with the organophosphorus nerve agents soman and sarin.
Biochemistry, 48, 2009
3NKM
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CRYSTAL STRUCTURE OF MOUSE AUTOTAXIN
Descriptor:Ectonucleotide pyrophosphatase/phosphodiesterase family member 2, N-ACETYL-D-GLUCOSAMINE, BETA-D-MANNOSE, ...
Authors:Nishimasu, H., Ishitani, R., Mihara, E., Takagi, J., Aoki, J., Nureki, O.
Deposit date:2010-06-20
Release date:2011-01-19
Last modified:2017-11-08
Method:X-RAY DIFFRACTION (2.002 Å)
Cite:Crystal structure of autotaxin and insight into GPCR activation by lipid mediators
Nat.Struct.Mol.Biol., 18, 2011
3NKN
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CRYSTAL STRUCTURE OF MOUSE AUTOTAXIN IN COMPLEX WITH 14:0-LPA
Descriptor:Ectonucleotide pyrophosphatase/phosphodiesterase family member 2, N-ACETYL-D-GLUCOSAMINE, BETA-D-MANNOSE, ...
Authors:Nishimasu, H., Ishitani, R., Mihara, E., Takagi, J., Aoki, J., Nureki, O.
Deposit date:2010-06-20
Release date:2011-01-19
Last modified:2017-11-08
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Crystal structure of autotaxin and insight into GPCR activation by lipid mediators
Nat.Struct.Mol.Biol., 18, 2011
3NKO
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CRYSTAL STRUCTURE OF MOUSE AUTOTAXIN IN COMPLEX WITH 16:0-LPA
Descriptor:Ectonucleotide pyrophosphatase/phosphodiesterase family member 2, N-ACETYL-D-GLUCOSAMINE, BETA-D-MANNOSE, ...
Authors:Nishimasu, H., Ishitani, R., Mihara, E., Takagi, J., Aoki, J., Nureki, O.
Deposit date:2010-06-20
Release date:2011-01-19
Last modified:2017-11-08
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Crystal structure of autotaxin and insight into GPCR activation by lipid mediators
Nat.Struct.Mol.Biol., 18, 2011
3NKP
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CRYSTAL STRUCTURE OF MOUSE AUTOTAXIN IN COMPLEX WITH 18:1-LPA
Descriptor:Ectonucleotide pyrophosphatase/phosphodiesterase family member 2, N-ACETYL-D-GLUCOSAMINE, BETA-D-MANNOSE, ...
Authors:Nishimasu, H., Ishitani, R., Mihara, E., Takagi, J., Aoki, J., Nureki, O.
Deposit date:2010-06-20
Release date:2011-01-19
Last modified:2017-11-08
Method:X-RAY DIFFRACTION (1.751 Å)
Cite:Crystal structure of autotaxin and insight into GPCR activation by lipid mediators
Nat.Struct.Mol.Biol., 18, 2011
3NKQ
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CRYSTAL STRUCTURE OF MOUSE AUTOTAXIN IN COMPLEX WITH 18:3-LPA
Descriptor:Ectonucleotide pyrophosphatase/phosphodiesterase family member 2, N-ACETYL-D-GLUCOSAMINE, BETA-D-MANNOSE, ...
Authors:Nishimasu, H., Ishitani, R., Mihara, E., Takagi, J., Aoki, J., Nureki, O.
Deposit date:2010-06-20
Release date:2011-01-19
Last modified:2017-11-08
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Crystal structure of autotaxin and insight into GPCR activation by lipid mediators
Nat.Struct.Mol.Biol., 18, 2011
3NKR
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CRYSTAL STRUCTURE OF MOUSE AUTOTAXIN IN COMPLEX WITH 22:6-LPA
Descriptor:Ectonucleotide pyrophosphatase/phosphodiesterase family member 2, N-ACETYL-D-GLUCOSAMINE, BETA-D-MANNOSE, ...
Authors:Nishimasu, H., Ishitani, R., Mihara, E., Takagi, J., Aoki, J., Nureki, O.
Deposit date:2010-06-20
Release date:2011-01-19
Last modified:2017-11-08
Method:X-RAY DIFFRACTION (1.704 Å)
Cite:Crystal structure of autotaxin and insight into GPCR activation by lipid mediators
Nat.Struct.Mol.Biol., 18, 2011
4GEL
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CRYSTAL STRUCTURE OF ZUCCHINI
Descriptor:Mitochondrial cardiolipin hydrolase, ZINC ION, PHOSPHATE ION, ...
Authors:Nishimasu, H., Fukuhara, S., Ishitani, R., Nureki, O.
Deposit date:2012-08-02
Release date:2012-10-17
Last modified:2017-11-15
Method:X-RAY DIFFRACTION (1.756 Å)
Cite:Structure and function of Zucchini endoribonuclease in piRNA biogenesis
Nature, 491, 2012
4GEM
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CRYSTAL STRUCTURE OF ZUCCHINI (K171A)
Descriptor:Mitochondrial cardiolipin hydrolase, ZINC ION, 1,2-ETHANEDIOL
Authors:Nishimasu, H., Fukuhara, S., Ishitani, R., Nureki, O.
Deposit date:2012-08-02
Release date:2012-10-17
Last modified:2017-11-15
Method:X-RAY DIFFRACTION (2.206 Å)
Cite:Structure and function of Zucchini endoribonuclease in piRNA biogenesis
Nature, 491, 2012
4GEN
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CRYSTAL STRUCTURE OF ZUCCHINI (MONOMER)
Descriptor:Mitochondrial cardiolipin hydrolase, CHLORIDE ION
Authors:Nishimasu, H., Fukuhara, S., Ishitani, R., Nureki, O.
Deposit date:2012-08-02
Release date:2012-10-17
Last modified:2017-11-15
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structure and function of Zucchini endoribonuclease in piRNA biogenesis
Nature, 491, 2012
4GTW
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CRYSTAL STRUCTURE OF MOUSE ENPP1 IN COMPLEX WITH AMP
Descriptor:Ectonucleotide pyrophosphatase/phosphodiesterase family member 2, Alkaline phosphodiesterase I, N-ACETYL-D-GLUCOSAMINE, ...
Authors:Kato, K., Nishimasu, H., Ishitani, R., Nureki, O.
Deposit date:2012-08-29
Release date:2012-11-07
Last modified:2018-06-20
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Crystal structure of Enpp1, an extracellular glycoprotein involved in bone mineralization and insulin signaling.
Proc.Natl.Acad.Sci.USA, 109, 2012
4GTX
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CRYSTAL STRUCTURE OF MOUSE ENPP1 IN COMPLEX WITH TMP
Descriptor:Ectonucleotide pyrophosphatase/phosphodiesterase family member 2, Alkaline phosphodiesterase I, N-ACETYL-D-GLUCOSAMINE, ...
Authors:Kato, K., Nishimasu, H., Ishitani, R., Nureki, O.
Deposit date:2012-08-29
Release date:2012-11-07
Last modified:2018-06-20
Method:X-RAY DIFFRACTION (3.201 Å)
Cite:Crystal structure of Enpp1, an extracellular glycoprotein involved in bone mineralization and insulin signaling.
Proc.Natl.Acad.Sci.USA, 109, 2012
4GTY
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CRYSTAL STRUCTURE OF MOUSE ENPP1 IN COMPLEX WITH GMP
Descriptor:Ectonucleotide pyrophosphatase/phosphodiesterase family member 2, Alkaline phosphodiesterase I, N-ACETYL-D-GLUCOSAMINE, ...
Authors:Kato, K., Nishimasu, H., Ishitani, R., Nureki, O.
Deposit date:2012-08-29
Release date:2012-11-07
Last modified:2018-06-20
Method:X-RAY DIFFRACTION (3.19 Å)
Cite:Crystal structure of Enpp1, an extracellular glycoprotein involved in bone mineralization and insulin signaling.
Proc.Natl.Acad.Sci.USA, 109, 2012
4GTZ
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CRYSTAL STRUCTURE OF MOUSE ENPP1 IN COMPLEX WITH CMP
Descriptor:Ectonucleotide pyrophosphatase/phosphodiesterase family member 2, Alkaline phosphodiesterase I, N-ACETYL-D-GLUCOSAMINE, ...
Authors:Kato, K., Nishimasu, H., Ishitani, R., Nureki, O.
Deposit date:2012-08-29
Release date:2012-11-07
Last modified:2018-06-20
Method:X-RAY DIFFRACTION (3.191 Å)
Cite:Crystal structure of Enpp1, an extracellular glycoprotein involved in bone mineralization and insulin signaling.
Proc.Natl.Acad.Sci.USA, 109, 2012
3WAV
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CRYSTAL STRUCTURE OF AUTOTAXIN IN COMPLEX WITH COMPOUND 10
Descriptor:Ectonucleotide pyrophosphatase/phosphodiesterase family member 2, N-ACETYL-D-GLUCOSAMINE, BETA-D-MANNOSE, ...
Authors:Nishimasu, H., Ishitani, R., Nureki, O.
Deposit date:2013-05-09
Release date:2013-07-31
Last modified:2013-10-16
Method:X-RAY DIFFRACTION (1.797 Å)
Cite:Screening and X-ray Crystal Structure-based Optimization of Autotaxin (ENPP2) Inhibitors, Using a Newly Developed Fluorescence Probe
Acs Chem.Biol., 8, 2013
3WAW
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CRYSTAL STRUCTURE OF AUTOTAXIN IN COMPLEX WITH 2BOA
Descriptor:Ectonucleotide pyrophosphatase/phosphodiesterase family member 2, N-ACETYL-D-GLUCOSAMINE, BETA-D-MANNOSE, ...
Authors:Nishimasu, H., Ishitani, R., Nureki, O.
Deposit date:2013-05-09
Release date:2013-07-31
Last modified:2013-10-16
Method:X-RAY DIFFRACTION (1.954 Å)
Cite:Screening and X-ray Crystal Structure-based Optimization of Autotaxin (ENPP2) Inhibitors, Using a Newly Developed Fluorescence Probe
Acs Chem.Biol., 8, 2013
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