Author results

2V4M
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THE ISOMERASE DOMAIN OF HUMAN GLUTAMINE-FRUCTOSE-6-PHOSPHATE TRANSAMINASE 1 (GFPT1) IN COMPLEX WITH FRUCTOSE 6-PHOSPHATE
Descriptor:GLUCOSAMINE--FRUCTOSE-6-PHOSPHATE AMINOTRANSFERASE [ISOMERIZING] 1, FRUCTOSE -6-PHOSPHATE, CHLORIDE ION
Authors:Moche, M., Lehtio, L., Andersson, J., Arrowsmith, C.H., Berglund, H., Collins, R., Dahlgren, L.G., Edwards, A.M., Flodin, S., Flores, A., Graslund, S., Hammarstrom, M., Johansson, A., Johansson, I., Karlberg, T., Kotenyova, T., Nilsson, M.E., Nyman, T., Persson, C., Sagemark, J., Svensson, S., Schueler, H., Thorsell, A.G., Tresaugues, L., Uppenberg, J., Van Den Berg, S., Welin, M., Wisniewska, M., Weigelt, J., Nordlund, P., Wikstrom, M.
Deposit date:2008-09-26
Release date:2008-10-07
Last modified:2018-01-17
Method:X-RAY DIFFRACTION (2.29 Å)
Cite:The Isomerase Domain of Human Gfpt1 in Complex with Fructose 6-Phosphate
To be Published
2V4U
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HUMAN CTP SYNTHETASE 2 - GLUTAMINASE DOMAIN IN COMPLEX WITH 5-OXO-L- NORLEUCINE
Descriptor:CTP SYNTHASE 2
Authors:Welin, M., Moche, M., Andersson, J., Arrowsmith, C.H., Berglund, H., Collins, R., Dahlgren, L.G., Edwards, A.M., Flodin, S., Flores, A., Graslund, S., Hammarstrom, M., Johansson, A., Johansson, I., Karlberg, T., Kotenyova, T., Lehtio, L., Nilsson, M.E., Nyman, T., Olesen, K., Persson, C., Sagemark, J., Schueler, H., Thorsell, A.G., Tresaugues, L., Van Den Berg, S., Wisniewska, M., Weigelt, J., Wikstrom, M., Nordlund, P.
Deposit date:2008-09-29
Release date:2008-10-07
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Human Ctp Synthetase 2 - Glutaminase Domain in Complex with 5-Oxo-L-Norleucine
To be Published
2VR2
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HUMAN DIHYDROPYRIMIDINASE
Descriptor:DIHYDROPYRIMIDINASE, ZINC ION, CHLORIDE ION
Authors:Welin, M., Karlberg, T., Andersson, J., Arrowsmith, C.H., Berglund, H., Busam, R.D., Collins, R., Dahlgren, L.G., Edwards, A.M., Flodin, S., Flores, A., Graslund, S., Hammarstrom, M., Herman, M.D., Johansson, I., Kallas, A., Kotenyova, T., Lehtio, L., Moche, M., Nilsson, M.E., Nyman, T., Persson, C., Sagemark, J., Svensson, L., Thorsell, A.G., Tresaugues, L., Van Den Berg, S., Weigelt, J., Wikstrom, M., Nordlund, P., Structural Genomics Consortium (SGC)
Deposit date:2008-03-25
Release date:2008-04-01
Last modified:2015-05-06
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:The Crystal Structure of Human Dihydropyrimidinase
To be Published
3D8B
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CRYSTAL STRUCTURE OF HUMAN FIDGETIN-LIKE PROTEIN 1 IN COMPLEX WITH ADP
Descriptor:Fidgetin-like protein 1, ADENOSINE-5'-DIPHOSPHATE
Authors:Karlberg, T., Wisniewska, M., Andersson, J., Arrowsmith, C.H., Berglund, H., Busam, R.D., Collins, R., Dahlgren, L.G., Edwards, A.M., Flodin, S., Flores, A., Graslund, S., Hammarstrom, M., Johansson, A., Johansson, I., Kallas, A., Kotenyova, T., Lehtio, L., Moche, M., Nilsson, M.E., Nordlund, P., Nyman, T., Olesen, K., Persson, C., Sagemark, J., Thorsell, A.G., Tresaugues, L., Van Den Berg, S., Welin, M., Wikstrom, M., Schuler, H., Structural Genomics Consortium (SGC)
Deposit date:2008-05-23
Release date:2008-08-26
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Human fidgetin-like protein 1.
To be Published
3DH1
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CRYSTAL STRUCTURE OF HUMAN TRNA-SPECIFIC ADENOSINE-34 DEAMINASE SUBUNIT ADAT2
Descriptor:tRNA-specific adenosine deaminase 2, ZINC ION
Authors:Welin, M., Tresaugues, L., Andersson, J., Arrowsmith, C.H., Berglund, H., Collins, R., Dahlgren, L.G., Edwards, A.M., Flodin, S., Flores, A., Graslund, S., Hammarstrom, M., Johansson, A., Johansson, I., Karlberg, T., Kotenyova, T., Lehtio, L., Moche, M., Nilsson, M.E., Nyman, T., Olesen, K., Persson, C., Sagemark, J., Schueler, H., Thorsell, A.G., van der Berg, S., Wisniewska, M., Wikstrom, M., Nordlund, P., Structural Genomics Consortium (SGC)
Deposit date:2008-06-16
Release date:2008-09-09
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Crystal structure of human tRNA-specific adenosine-34 deaminase subunit ADAT2.
To be Published
3DYD
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HUMAN TYROSINE AMINOTRANSFERASE
Descriptor:Tyrosine aminotransferase, PYRIDOXAL-5'-PHOSPHATE
Authors:Karlberg, T., Moche, M., Andersson, J., Arrowsmith, C.H., Berglund, H., Collins, R., Dahlgren, L.G., Edwards, A.M., Flodin, S., Flores, A., Graslund, S., Hammarstrom, M., Johansson, A., Johansson, I., Kotenyova, T., Lehtio, L., Nilsson, M.E., Nordlund, P., Nyman, T., Olesen, K., Persson, C., Sagemark, J., Thorsell, A.G., Tresaugues, L., Van Den Berg, S., Weigelt, J., Welin, M., Wikstrom, M., Wisniewska, M., Schuler, H., Structural Genomics Consortium (SGC)
Deposit date:2008-07-27
Release date:2008-08-19
Last modified:2018-01-24
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Human Tyrosine Aminotransferase
To be Published
3E77
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HUMAN PHOSPHOSERINE AMINOTRANSFERASE IN COMPLEX WITH PLP
Descriptor:Phosphoserine aminotransferase, PYRIDOXAL-5'-PHOSPHATE, GLYCEROL
Authors:Lehtio, L., Karlberg, T., Andersson, J., Arrowsmith, C.H., Berglund, H., Bountra, C., Collins, R., Dahlgren, L.G., Edwards, A.M., Flodin, S., Flores, A., Graslund, S., Hammarstrom, M., Johansson, A., Johansson, I., Kotenyova, T., Moche, M., Nilsson, M.E., Nordlund, P., Nyman, T., Olesen, K., Persson, C., Sagemark, J., Thorsell, S.G., Tresaugues, L., Van Den Berg, S., Welin, M., Wikstrom, M., Wisniewska, M., Weigelt, J., Schueler, H., Structural Genomics Consortium (SGC)
Deposit date:2008-08-18
Release date:2008-08-26
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Human phosphoserine aminotransferase in complex with PLP
TO BE PUBLISHED
3EC8
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THE CRYSTAL STRUCTURE OF THE RA DOMAIN OF FLJ10324 (RADIL)
Descriptor:Putative uncharacterized protein FLJ10324, CHLORIDE ION, LEAD (II) ION, ...
Authors:Wisniewska, M., Lehtio, L., Andersson, J., Arrowsmith, C.H., Collins, R., Dahlgren, L.G., Edwards, A.M., Flodin, S., Flores, A., Graslund, S., Hammarstrom, M., Johansson, A., Johansson, I., Karlberg, T., Kotenyova, T., Moche, M., Nilsson, M.E., Nordlund, P., Nyman, T., Olesen, K., Persson, C., Sagemark, J., Schueler, H., Thorsell, A.G., Tresaugues, L., van den Berg, S., Weigelt, J., Welin, M., Wikstrom, M., Berglund, H., Structural Genomics Consortium (SGC)
Deposit date:2008-08-29
Release date:2008-09-30
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:The crystal structure of the RA domain of FLJ10324 (RADIL)
to be published
3ELB
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HUMAN CTP: PHOSPHOETHANOLAMINE CYTIDYLYLTRANSFERASE IN COMPLEX WITH CMP
Descriptor:Ethanolamine-phosphate cytidylyltransferase, CYTIDINE-5'-MONOPHOSPHATE, GLYCEROL
Authors:Karlberg, T., Welin, M., Andersson, J., Arrowsmith, C.H., Berglund, H., Bountra, C., Collins, R., Dahlgren, L.G., Edwards, A.M., Flodin, S., Flores, A., Graslund, S., Hammarstrom, M., Johansson, A., Johansson, I., Kotenyova, T., Lehtio, L., Moche, M., Nilsson, M.E., Nordlund, P., Nyman, T., Persson, C., Sagemark, J., Thorsell, A.G., Tresaugues, L., Van Den Berg, S., Weigelt, J., Wikstrom, M., Wisniewska, M., Schuler, H., Structural Genomics Consortium (SGC)
Deposit date:2008-09-22
Release date:2008-10-21
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Human CTP:Phosphoethanolamine Cytidylyltransferase
To be Published
3EQ5
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CRYSTAL STRUCTURE OF FRAGMENT 137 TO 238 OF THE HUMAN SKI-LIKE PROTEIN
Descriptor:Ski-like protein
Authors:Tresaugues, L., Wisniewska, M., Andersson, J., Arrowsmith, C.H., Berglund, H., Bountra, C., Collins, R., Dahlgren, L.G., Edwards, A.M., Flodin, S., Flores, A., Graslund, S., Hammarstrom, M., Johansson, A., Johansson, I., Karlberg, T., Kotenyova, T., Lehtio, L., Moche, M., Nilsson, M.E., Nyman, T., Olesen, K., Persson, C., Sagemark, J., Schueler, H., Thorsell, A.G., Van Den Berg, S., Welin, M., Wikstrom, M., Weigelt, J., Nordlund, P., Structural Genomics Consortium (SGC)
Deposit date:2008-09-30
Release date:2009-01-27
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.45 Å)
Cite:Crystal structure of fragment 137 to 238 of the human Ski-like protein.
To be Published
3F0W
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HUMAN NUMB-LIKE PROTEIN, PHOSPHOTYROSINE INTERACTION DOMAIN
Descriptor:Numb-like protein, SULFATE ION, CHLORIDE ION
Authors:Lehtio, L., Moche, M., Andersson, J., Arrowsmith, C.H., Berglund, H., Bountra, C., D Busam, R., Collins, R., Dahlgren, L.G., Edwards, A.M., Flodin, S., Flores, A., Graslund, S., Hammarstrom, M., Johansson, A., Johansson, I., Karlberg, T., Kotenyova, T., Nilsson, M.E., Nyman, T., Persson, C., Sagemark, J., Schueler, H., Thorsell, A.G., Tresaugues, L., Van Den Berg, S., Weigelt, J., Welin, M., Wikstrom, M., Wisniewska, M., Nordlund, P., Structural Genomics Consortium (SGC)
Deposit date:2008-10-27
Release date:2008-11-04
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Human NUMB-like protein, phosphotyrosine interaction domain
To be Published
1H78
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STRUCTURAL BASIS FOR ALLOSTERIC SUBSTRATE SPECIFICITY REGULATION IN CLASS III RIBONUCLEOTIDE REDUCTASES: NRDD IN COMPLEX WITH DCTP.
Descriptor:ANAEROBIC RIBONUCLEOTIDE-TRIPHOSPHATE REDUCTASE LARGE CHAIN, 2'-DEOXYCYTIDINE-5'-TRIPHOSPHATE, MAGNESIUM ION
Authors:Larsson, K.-M., Andersson, J., Sjoeberg, B.-M., Nordlund, P., Logan, D.T.
Deposit date:2001-07-04
Release date:2002-07-04
Last modified:2018-10-24
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structural Basis for Allosteric Substrate Specificty Regulation in Anaerobic Ribonucleotide Reductase
Structure, 9, 2001
1H79
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STRUCTURAL BASIS FOR ALLOSTERIC SUBSTRATE SPECIFICITY REGULATION IN CLASS III RIBONUCLEOTIDE REDUCTASES: NRDD IN COMPLEX WITH DTTP
Descriptor:ANAEROBIC RIBONUCLEOTIDE-TRIPHOSPHATE REDUCTASE LARGE CHAIN, THYMIDINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ...
Authors:Larsson, K.-M., Andersson, J., Sjoeberg, B.-M., Nordlund, P., Logan, D.T.
Deposit date:2001-07-04
Release date:2002-03-28
Last modified:2018-10-24
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Structural Basis for Allosteric Substrate Specificty Regulation in Anaerobic Ribonucleotide Reductase
Structure, 9, 2001
1H7A
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STRUCTURAL BASIS FOR ALLOSTERIC SUBSTRATE SPECIFICITY REGULATION IN CLASS III RIBONUCLEOTIDE REDUCTASES: NRDD IN COMPLEX WITH DATP
Descriptor:ANAEROBIC RIBONUCLEOTIDE-TRIPHOSPHATE REDUCTASE LARGE CHAIN, 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, FE (II) ION, ...
Authors:Larsson, K.-M., Andersson, J., Sjoeberg, B.-M., Nordlund, P., Logan, D.T.
Deposit date:2001-07-04
Release date:2002-03-28
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.75 Å)
Cite:Structural Basis for Allosteric Substrate Specificty Regulation in Anaerobic Ribonucleotide Reductase
Structure, 9, 2001
1H7B
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STRUCTURAL BASIS FOR ALLOSTERIC SUBSTRATE SPECIFICITY REGULATION IN CLASS III RIBONUCLEOTIDE REDUCTASES, NATIVE NRDD
Descriptor:ANAEROBIC RIBONUCLEOTIDE-TRIPHOSPHATE REDUCTASE LARGE CHAIN, PHOSPHATE ION
Authors:Larsson, K.-M., Andersson, J., Sjoeberg, B.-M., Nordlund, P., Logan, D.T.
Deposit date:2001-07-04
Release date:2002-03-28
Last modified:2018-01-17
Method:X-RAY DIFFRACTION (2.45 Å)
Cite:Structural Basis for Allosteric Substrate Specificty Regulation in Anaerobic Ribonucleotide Reductase
Structure, 9, 2001
1HK8
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STRUCTURAL BASIS FOR ALLOSTERIC SUBSTRATE SPECIFICITY REGULATION IN CLASS III RIBONUCLEOTIDE REDUCTASES: NRDD IN COMPLEX WITH DGTP
Descriptor:ANAEROBIC RIBONUCLEOTIDE-TRIPHOSPHATE REDUCTASE, 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, ZINC ION, ...
Authors:Larsson, K.-M., Andersson, J., Sjoeberg, B.-M., Nordlund, P., Logan, D.T.
Deposit date:2003-03-06
Release date:2003-03-27
Last modified:2018-04-18
Method:X-RAY DIFFRACTION (2.45 Å)
Cite:A Metal-Binding Site in the Catalytic Subunit of Anaerobic Ribonucleotide Reductase.
Proc.Natl.Acad.Sci.USA, 100, 2003
2VUX
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HUMAN RIBONUCLEOTIDE REDUCTASE, SUBUNIT M2 B
Descriptor:RIBONUCLEOSIDE-DIPHOSPHATE REDUCTASE SUBUNIT M2 B, FE (III) ION
Authors:Welin, M., Moche, M., Andersson, J., Arrowsmith, C.H., Berglund, H., Busam, R.D., Collins, R., Dahlgren, L.G., Edwards, A.M., Flodin, S., Flores, A., Graslund, S., Hammarstrom, M., Herman, M.D., Johansson, A., Johansson, I., Kallas, A., Karlberg, T., Kotenyova, T., Lehtio, L., Nilsson, M.E., Nyman, T., Persson, C., Sagemark, J., Schueler, H., Svensson, L., Thorsell, A.G., Tresaugues, L., van Den Berg, S., Weigelt, J., Wikstrom, M., Nordlund, P., Structural Genomics Consortium (SGC)
Deposit date:2008-05-31
Release date:2008-07-15
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Human Ribonucleotide Reductase, Subunit M2 B
To be Published
3EWS
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HUMAN DEAD-BOX RNA-HELICASE DDX19 IN COMPLEX WITH ADP
Descriptor:ATP-dependent RNA helicase DDX19B, ADENOSINE-5'-DIPHOSPHATE
Authors:Lehtio, l., Karlberg, t., Andersson, j., Arrowsmith, c.h., Berglund, h., Bountra, c., Collins, r., Dahlgren, l.g., Edwards, a.m., Flodin, s., Flores, a., Graslund, s., Hammarstrom, m., Johansson, a., Johansson, i., Kotenyova, t., Moche, m., Nilsson, m.e., Nordlund, p., Nyman, t., Olesen, k., Persson, c., Sagemark, j., Thorsell, a.g., Tresaugues, l., Van den berg, s., Weigelt, j., Welin, m., Wikstrom, m., Wisniewska, m., Schueler, h., Structural Genomics Consortium (SGC)
Deposit date:2008-10-16
Release date:2008-11-04
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:The DEXD/H-box RNA Helicase DDX19 Is Regulated by an {alpha}-Helical Switch.
J.Biol.Chem., 284, 2009
3CZD
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CRYSTAL STRUCTURE OF HUMAN GLUTAMINASE IN COMPLEX WITH L-GLUTAMATE
Descriptor:Glutaminase kidney isoform, SULFATE ION, GLUTAMIC ACID, ...
Authors:Karlberg, T., Welin, M., Andersson, J., Arrowsmith, C.H., Berglund, H., Busam, R.D., Collins, R., Dahlgren, L.G., Edwards, A.M., Flodin, S., Flores, A., Graslund, S., Hammarstrom, M., Johansson, A., Johansson, I., Kallas, A., Kotenyova, T., Lehtio, L., Moche, M., Nilsson, M.E., Nordlund, P., Nyman, T., Persson, C., Sagemark, J., Svensson, L., Thorsell, A.G., Tresaugues, L., Van Den Berg, S., Wikstrom, M., Schuler, H., Structural Genomics Consortium (SGC)
Deposit date:2008-04-29
Release date:2008-07-01
Last modified:2018-03-07
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Structural basis for the allosteric inhibitory mechanism of human kidney-type glutaminase (KGA) and its regulation by Raf-Mek-Erk signaling in cancer cell metabolism.
Proc.Natl.Acad.Sci.USA, 109, 2012
2VXO
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HUMAN GMP SYNTHETASE IN COMPLEX WITH XMP
Descriptor:GMP SYNTHASE [GLUTAMINE-HYDROLYZING], XANTHOSINE-5'-MONOPHOSPHATE, SULFATE ION
Authors:Welin, M., Lehtio, L., Andersson, J., Arrowsmith, C.H., Berglund, H., Collins, R., Dahlgren, L.G., Edwards, A.M., Flodin, S., Flores, A., Graslund, S., Hammarstrom, M., Johansson, A., Johansson, I., Karlberg, T., Kotenyova, T., Moche, M., Nilsson, M.E., Nyman, T., Olesen, K., Persson, C., Sagemark, J., Schueler, H., Thorsell, A.G., Tresaugues, L., Van Den Berg, S., Wisniewska, M., Wikstrom, M., Nordlund, P.
Deposit date:2008-07-08
Release date:2008-08-12
Last modified:2013-11-13
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Substrate Specificity and Oligomerization of Human Gmp Synthetase
J.Mol.Biol., 425, 2013
3DKP
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HUMAN DEAD-BOX RNA-HELICASE DDX52, CONSERVED DOMAIN I IN COMPLEX WITH ADP
Descriptor:Probable ATP-dependent RNA helicase DDX52, MAGNESIUM ION, ADENOSINE-5'-DIPHOSPHATE, ...
Authors:Lehtio, L., Karlberg, T., Andersson, J., Arrowsmith, C.H., Berglund, H., Collins, R., Dahlgren, L.G., Edwards, A.M., Flodin, S., Flores, A., Graslund, S., Hammarstrom, M., Johansson, A., Johansson, I., Kotenyova, T., Moche, M., Nilsson, M.E., Nordlund, P., Nyman, T., Olesen, K., Persson, C., Sagemark, J., Thorsell, A.G., Tresaugues, L., van den Berg, S., Welin, M., Wisniewska, M., Wikstrom, M., Schueler, H., Structural Genomics Consortium (SGC)
Deposit date:2008-06-25
Release date:2008-08-12
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Comparative Structural Analysis of Human DEAD-Box RNA Helicases.
Plos One, 5, 2010
5LFS
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LAMBDA-[RU(BPY)2(DPPZ)]2+ BOUND TO BROMINATED DNA
Descriptor:DNA (5'-D(*GP*CP*CP*G)-3'), DNA (5'-D(*(CBR)P*GP*GP*C)-3'), BARIUM ION, ...
Authors:Hall, J.P., Cardin, C.J.
Deposit date:2016-07-04
Release date:2017-02-15
Last modified:2017-08-30
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Guanine Can Direct Binding Specificity of Ru-dipyridophenazine (dppz) Complexes to DNA through Steric Effects.
Chemistry, 23, 2017
5LFW
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LAMBDA-[RU(PHEN)2(DPPZ)]2+ BOUND TO A SHORT SUBSTITUTED DNA SEQUENCE
Descriptor:DNA (5'-D(*GP*CP*CP*G)-3'), DNA (5'-D(*(CBR)P*GP*GP*C)-3'), BARIUM ION, ...
Authors:Hall, J.P., Cardin, C.J.
Deposit date:2016-07-04
Release date:2017-02-15
Last modified:2017-08-30
Method:X-RAY DIFFRACTION (1.28 Å)
Cite:Guanine Can Direct Binding Specificity of Ru-dipyridophenazine (dppz) Complexes to DNA through Steric Effects.
Chemistry, 23, 2017
5LFX
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LAMBDA-[RU(PHEN)2(DPPZ-11,12-ME)]2+ BOUND TO A SHORT SUBSTITUTED DNA SEQUENCE
Descriptor:DNA (5'-D(*GP*CP*CP*G)-3'), DNA (5'-D(*(CBR)P*GP*GP*C)-3'), BARIUM ION, ...
Authors:Hall, J.P., Cardin, C.J.
Deposit date:2016-07-04
Release date:2017-02-15
Last modified:2017-08-30
Method:X-RAY DIFFRACTION (1.56 Å)
Cite:Guanine Can Direct Binding Specificity of Ru-dipyridophenazine (dppz) Complexes to DNA through Steric Effects.
Chemistry, 23, 2017