4DVB
| The crystal structure of the Fab fragment of pro-uPA antibody mAb-112 | Descriptor: | Fab fragment of pro-uPA antibody mAb-112, SULFATE ION, TETRAETHYLENE GLYCOL | Authors: | Jiang, L, Botkjaer, K.A, Andersen, L.M, Yuan, C, Andreasen, P.A, Huang, M. | Deposit date: | 2012-02-23 | Release date: | 2013-01-16 | Method: | X-RAY DIFFRACTION (1.93 Å) | Cite: | Rezymogenation of active urokinase induced by an inhibitory antibody. Biochem.J., 449, 2013
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4DVA
| The crystal structure of human urokinase-type plasminogen activator catalytic domain | Descriptor: | HEXAETHYLENE GLYCOL, SULFATE ION, Urokinase-type plasminogen activator | Authors: | Jiang, L, Botkjaer, K.A, Andersen, L.M, Yuan, C, Andreasen, P.A, Huang, M. | Deposit date: | 2012-02-23 | Release date: | 2013-01-16 | Method: | X-RAY DIFFRACTION (1.94 Å) | Cite: | Rezymogenation of active urokinase induced by an inhibitory antibody Biochem.J., 449, 2013
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4DW2
| The crystal structure of uPA in complex with the Fab fragment of mAb-112 | Descriptor: | Fab fragment of pro-uPA antibody mAb-112, SULFATE ION, Urokinase-type plasminogen activator | Authors: | Jiang, L, Botkjaer, K.A, Andersen, L.M, Yuan, C, Andreasen, P.A, Huang, M. | Deposit date: | 2012-02-24 | Release date: | 2013-01-16 | Method: | X-RAY DIFFRACTION (2.97 Å) | Cite: | Rezymogenation of active urokinase induced by an inhibitory antibody. Biochem.J., 449, 2013
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7AHV
| Anti-FIXa Fab of mim8 in complex with human FIXa | Descriptor: | CALCIUM ION, Coagulation factor IX, L-alpha-glutamyl-N-{(1S)-4-{[amino(iminio)methyl]amino}-1-[(1S)-2-chloro-1-hydroxyethyl]butyl}glycinamide, ... | Authors: | Johansson, E. | Deposit date: | 2020-09-25 | Release date: | 2021-07-07 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (3.11 Å) | Cite: | A factor VIIIa-mimetic bispecific antibody, Mim8, ameliorates bleeding upon severe vascular challenge in hemophilia A mice. Blood, 138, 2021
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7AHU
| Anti-FX Fab of mim8 in complex with human FXa | Descriptor: | Anti-FX Fab of mim8 heavy chain, Anti-FX Fab of mim8 light chain, CALCIUM ION, ... | Authors: | Johansson, E. | Deposit date: | 2020-09-25 | Release date: | 2021-07-07 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | A factor VIIIa-mimetic bispecific antibody, Mim8, ameliorates bleeding upon severe vascular challenge in hemophilia A mice. Blood, 138, 2021
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