Author results

2PK2
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CYCLIN BOX STRUCTURE OF THE P-TEFB SUBUNIT CYCLIN T1 DERIVED FROM A FUSION COMPLEX WITH EIAV TAT
Descriptor:Cyclin-T1, Protein Tat
Authors:Anand, K., Schulte, A., Fujinaga, K., Scheffzek, K., Geyer, M.
Deposit date:2007-04-17
Release date:2007-07-03
Last modified:2017-07-26
Method:X-RAY DIFFRACTION (2.67 Å)
Cite:Cyclin Box Structure of the P-TEFb Subunit Cyclin T1 Derived from a Fusion Complex with EIAV Tat.
J.Mol.Biol., 370, 2007
2W2H
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STRUCTURAL BASIS OF TRANSCRIPTION ACTIVATION BY THE CYCLIN T1-TAT-TAR RNA COMPLEX FROM EIAV
Descriptor:CYCLIN-T1, PROTEIN TAT, 5'-R(*GP*CP*UP*CP*AP*GP*AP*UP*CP*UP *GP*CP*GP*GP*UP*CP*UP*GP*AP*GP*C)-3', ...
Authors:Anand, K., Geyer, M.
Deposit date:2008-10-30
Release date:2008-12-09
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3.25 Å)
Cite:Structural Insights Into the Cyclin T1-Tat-Tar RNA Transcription Activation Complex from Eiav.
Nat.Struct.Mol.Biol., 15, 2008
4A6F
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CRYSTAL STRUCTURE OF SLM1-PH DOMAIN IN COMPLEX WITH PHOSPHOSERINE
Descriptor:PHOSPHATIDYLINOSITOL 4,5-BISPHOSPHATE-BINDING PROTEIN SLM1, PHOSPHATE ION, PHOSPHOSERINE
Authors:Anand, K., Maeda, K., Gavin, A.C.
Deposit date:2011-11-02
Release date:2012-06-13
Last modified:2013-02-06
Method:X-RAY DIFFRACTION (1.68 Å)
Cite:Structural Analyses of Slm1-Ph Domain Demonstrate Ligand Binding in the Non-Canonical Site
Plos One, 7, 2012
4A6H
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CRYSTAL STRUCTURE OF SLM1-PH DOMAIN IN COMPLEX WITH INOSITOL-4- PHOSPHATE
Descriptor:PHOSPHATIDYLINOSITOL 4,5-BISPHOSPHATE-BINDING PROTEIN SLM1, PHOSPHATE ION, D-MYO-INOSITOL-4-PHOSPHATE
Authors:Anand, K., Maeda, K., Gavin, A.C.
Deposit date:2011-11-03
Release date:2012-06-13
Last modified:2015-03-25
Method:X-RAY DIFFRACTION (1.449 Å)
Cite:Structural Analyses of Slm1-Ph Domain Demonstrate Ligand Binding in the Non-Canonical Site
Plos One, 7, 2012
4A6K
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CRYSTAL STRUCTURE OF SLM1-PH DOMAIN IN COMPLEX WITH D-MYO-INOSITOL-4- PHOSPHATE
Descriptor:PHOSPHATIDYLINOSITOL 4,5-BISPHOSPHATE-BINDING PROTEIN SLM1, PHOSPHATE ION, D-MYO-INOSITOL-4-PHOSPHATE
Authors:Anand, K., Maeda, K., Gavin, A.C.
Deposit date:2011-11-04
Release date:2012-06-13
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structural Analyses of Slm1-Ph Domain Demonstrate Ligand Binding in the Non-Canonical Site
Plos One, 7, 2012
2X1V
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CRYSTAL STRUCTURE OF THE ACTIVATING H-RAS I163F MUTANT IN COSTELLO SYNDROME, BOUND TO MG-GDP
Descriptor:GTPASE HRAS, GUANOSINE-5'-DIPHOSPHATE
Authors:Anand, K.
Deposit date:2010-01-04
Release date:2010-01-12
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Crystal Structure of the Activating H-Ras I163F Mutant in Costello Syndrome, Bound to Mg-Gdp
To be Published
4A5K
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STRUCTURAL ANALYSES OF SLM1-PH DOMAIN DEMONSTRATE LIGAND BINDING IN THE NON-CANONICAL SITE
Descriptor:PHOSPHATIDYLINOSITOL 4,5-BISPHOSPHATE-BINDING PROTEIN SLM 1, SULFATE ION
Authors:Anand, K., Gavin, A.C.
Deposit date:2011-10-25
Release date:2012-06-13
Method:X-RAY DIFFRACTION (1.76 Å)
Cite:Structural Analyses of Slm1-Ph Domain Demonstrate Ligand Binding in the Non-Canonical Site
Plos One, 7, 2012
2VB0
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CRYSTAL STRUCTURE OF COXSACKIEVIRUS B3 PROTEINASE 3C
Descriptor:POLYPROTEIN 3BCD, CHLORIDE ION
Authors:Anand, K., Mesters, J.R., Goerlach, R., Zell, R., Hilgenfeld, R.
Deposit date:2007-09-05
Release date:2008-10-28
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Crystal Structure of Coxsackie Virus B3 Proteinase 3C
To be Published
1LVO
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STRUCTURE OF CORONAVIRUS MAIN PROTEINASE REVEALS COMBINATION OF A CHYMOTRYPSIN FOLD WITH AN EXTRA ALPHA-HELICAL DOMAIN
Descriptor:Replicase, hydrolase domain, SULFATE ION, ...
Authors:Anand, K., Palm, G.J., Mesters, J.R., Siddell, S.G., Ziebuhr, J., Hilgenfeld, R.
Deposit date:2002-05-29
Release date:2002-07-17
Last modified:2017-10-11
Method:X-RAY DIFFRACTION (1.96 Å)
Cite:Structure of coronavirus main proteinase reveals combination of a chymotrypsin fold with an extra alpha-helical domain.
EMBO J., 21, 2002
1P9S
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CORONAVIRUS MAIN PROTEINASE (3CLPRO) STRUCTURE: BASIS FOR DESIGN OF ANTI-SARS DRUGS
Descriptor:Replicase polyprotein 1ab, 1,4-DIETHYLENE DIOXIDE
Authors:Anand, K., Ziebuhr, J., Wadhwani, P., Mesters, J.R., Hilgenfeld, R.
Deposit date:2003-05-12
Release date:2003-05-20
Last modified:2017-10-11
Method:X-RAY DIFFRACTION (2.54 Å)
Cite:Coronavirus Main Proteinase (3CLpro) Structure: Basis for Design of anti-SARS Drugs
Science, 300, 2003
1P9U
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CORONAVIRUS MAIN PROTEINASE (3CLPRO) STRUCTURE: BASIS FOR DESIGN OF ANTI-SARS DRUGS
Descriptor:putative coronavirus nsp2 (3CL-PRO), PHQ-VNSTLQ-CHLOROMETHYLKETONE INHIBITOR, SULFATE ION, ...
Authors:Anand, K., Ziebuhr, J., Wadhwani, P., Mesters, J.R., Hilgenfeld, R.
Deposit date:2003-05-12
Release date:2003-05-20
Last modified:2017-10-11
Method:X-RAY DIFFRACTION (2.37 Å)
Cite:Coronavirus Main Proteinase (3CLpro) Structure: Basis for Design of anti-SARS Drugs
Science, 300, 2003
2WU8
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STRUCTURAL STUDIES OF PHOSPHOGLUCOSE ISOMERASE FROM MYCOBACTERIUM TUBERCULOSIS H37RV
Descriptor:GLUCOSE-6-PHOSPHATE ISOMERASE, SULFATE ION
Authors:Anand, K.
Deposit date:2009-10-01
Release date:2009-10-27
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:Structural Studies of Phosphoglucose Isomerase from Mycobacterium Tuberculosis H37Rv
Acta Crystallogr.,Sect.F, 66, 2010
3DGV
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CRYSTAL STRUCTURE OF THROMBIN ACTIVATABLE FIBRINOLYSIS INHIBITOR (TAFI)
Descriptor:Carboxypeptidase B2, N-ACETYL-D-GLUCOSAMINE, 2-(ACETYLAMINO)-2-DEOXY-A-D-GLUCOPYRANOSE, ...
Authors:Anand, K., Pallares, I., Valnickova, Z., Christensen, T., Schreuder, H., Enghild, J.
Deposit date:2008-06-16
Release date:2008-07-22
Last modified:2017-02-08
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:The crystal structure of TAFI provides the structural basis for the intrinsic activity of the proenzyme and short half-life of TAFIa
To be Published
4NST
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CRYSTAL STRUCTURE OF HUMAN CDK12/CYCLIN K IN COMPLEX WITH ADP-ALUMINUM FLUORIDE
Descriptor:Cyclin-dependent kinase 12, Cyclin-K, ADENOSINE-5'-DIPHOSPHATE, ...
Authors:Boesken, C.A., Farnung, L., Anand, K., Geyer, M.
Deposit date:2013-11-29
Release date:2014-03-26
Last modified:2014-10-01
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:The structure and substrate specificity of human Cdk12/Cyclin K.
Nat Commun, 5, 2014
4B2Z
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STRUCTURE OF OSH6 IN COMPLEX WITH PHOSPHATIDYLSERINE
Descriptor:Oxysterol-binding protein homolog 6, SULFATE ION, O-[(R)-{[(2R)-2,3-bis(octadecanoyloxy)propyl]oxy}(hydroxy)phosphoryl]-L-serine, ...
Authors:Maeda, K., Anand, K., Chiapparino, A., Kumar, A., Poletto, M., Kaksonen, M., Gavin, A.C.
Deposit date:2012-07-19
Release date:2013-06-26
Last modified:2018-12-12
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Interactome Map Uncovers Phosphatidylserine Transport by Oxysterol-Binding Proteins
Nature, 501, 2013
5EFQ
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CRYSTAL STRUCTURE OF HUMAN CDK13/CYCLIN K IN COMPLEX WITH ADP-ALUMINUM FLUORIDE
Descriptor:Cyclin-dependent kinase 13, Cyclin-K, ADENOSINE-5'-DIPHOSPHATE, ...
Authors:Hoenig, D., Greifenberg, A.K., Anand, K., Geyer, M.
Deposit date:2015-10-24
Release date:2015-12-30
Last modified:2016-01-27
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural and Functional Analysis of the Cdk13/Cyclin K Complex.
Cell Rep, 14, 2016
1UJ1
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CRYSTAL STRUCTURE OF SARS CORONAVIRUS MAIN PROTEINASE (3CLPRO)
Descriptor:3C-like proteinase
Authors:Yang, H., Yang, M., Liu, Y., Bartlam, M., Ding, Y., Lou, Z., Sun, L., Zhou, Z., Ye, S., Anand, K., Pang, H., Gao, G.F., Hilgenfeld, R., Rao, Z.
Deposit date:2003-07-25
Release date:2003-11-18
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:The crystal structures of severe acute respiratory syndrome virus main protease and its complex with an inhibitor
Proc.Natl.Acad.Sci.USA, 100, 2003
1UK2
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CRYSTAL STRUCTURE OF SARS CORONAVIRUS MAIN PROTEINASE (3CLPRO) AT PH8.0
Descriptor:3C-LIKE PROTEINASE
Authors:Yang, H., Yang, M., Liu, Y., Bartlam, M., Ding, Y., Lou, Z., Sun, L., Zhou, Z., Ye, S., Anand, K., Pang, H., Gao, G.F., Hilgenfeld, R., Rao, Z.
Deposit date:2003-08-14
Release date:2003-11-18
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:The crystal structures of severe acute respiratory syndrome virus main protease and its complex with an inhibitor
Proc.Natl.Acad.Sci.USA, 100, 2003
1UK3
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CRYSTAL STRUCTURE OF SARS CORONAVIRUS MAIN PROTEINASE (3CLPRO) AT PH7.6
Descriptor:3C-like proteinase
Authors:Yang, H., Yang, M., Liu, Y., Bartlam, M., Ding, Y., Lou, Z., Sun, L., Zhou, Z., Ye, S., Anand, K., Pang, H., Gao, G.F., Hilgenfeld, R., Rao, Z.
Deposit date:2003-08-14
Release date:2003-11-18
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:The crystal structures of severe acute respiratory syndrome virus main protease and its complex with an inhibitor
Proc.Natl.Acad.Sci.USA, 100, 2003
1UK4
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CRYSTAL STRUCTURE OF SARS CORONAVIRUS MAIN PROTEINASE (3CLPRO) COMPLEXED WITH AN INHIBITOR
Descriptor:3C-like proteinase, 5-mer peptide of inhibitor, CHLOROACETONE
Authors:Yang, H., Yang, M., Liu, Y., Bartlam, M., Ding, Y., Lou, Z., Sun, L., Zhou, Z., Ye, S., Anand, K., Pang, H., Gao, G.F., Hilgenfeld, R., Rao, Z.
Deposit date:2003-08-14
Release date:2003-11-18
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:The crystal structures of severe acute respiratory syndrome virus main protease and its complex with an inhibitor
Proc.Natl.Acad.Sci.USA, 100, 2003
3ZYD
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CRYSTAL STRUCTURE OF 3C PROTEASE OF COXSACKIEVIRUS B3
Descriptor:3C PROTEINASE, GLYCEROL
Authors:Tan, J., Anand, K., Mesters, J.R., Hilgenfeld, R.
Deposit date:2011-08-22
Release date:2012-08-29
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Peptidic Ab-Nonsaturated Ethyl Esters as Inhibitors of the 3C Protease of Coxsackie Virus B3: Crystal Structures, Antiviral Activities, and Resistance Mutations
To be Published
3ZYE
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CRYSTAL STRUCTURE OF 3C PROTEASE MUTANT (T68A) OF COXSACKIEVIRUS B3
Descriptor:3C PROTEINASE
Authors:Tan, J., Anand, K., Mesters, J.R., Hilgenfeld, R.
Deposit date:2011-08-22
Release date:2012-08-29
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Peptidic Alpha, Beta-Unsaturated Ethyl Esters as Inhibitors of the 3C Protease of Coxsackie Virus B3: Crystal Structures, Antiviral Activities, and Resistance Mutations
To be Published
3ZZ3
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CRYSTAL STRUCTURE OF 3C PROTEASE MUTANT (N126Y) OF COXSACKIEVIRUS B3
Descriptor:3C PROTEINASE
Authors:Tan, J., Anand, K., Mesters, J.R., Hilgenfeld, R.
Deposit date:2011-08-31
Release date:2012-09-19
Method:X-RAY DIFFRACTION (1.89 Å)
Cite:Peptidic Alpha, Beta-Unsaturated Ethyl Esters as Inhibitors of the 3C Protease of Coxsackie Virus B3: Crystal Structures, Antiviral Activities, and Resistance Mutations
To be Published
3ZZ4
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CRYSTAL STRUCTURE OF 3C PROTEASE MUTANT (T68A AND N126Y) OF COXSACKIEVIRUS B3
Descriptor:3C PROTEINASE
Authors:Tan, J., Anand, K., Mesters, J.R., Hilgenfeld, R.
Deposit date:2011-08-31
Release date:2012-09-19
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Peptidic Alpha, Beta-Unsaturated Ethyl Esters as Inhibitors of the 3C Protease of Coxsackie Virus B3: Crystal Structures, Antiviral Activities, and Resistance Mutations
To be Published
3ZZ5
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CRYSTAL STRUCTURE OF 3C PROTEASE OF COXSACKIEVIRUS B3 COMPLEXED WITH ALPHA, BETA-UNSATURATED ETHYL ESTER INHIBITOR 74
Descriptor:3C PROTEINASE, ETHYL (4R)-4-[(TERT-BUTOXYCARBONYL)AMINO]-5-[(3S)-2-OXOPYRROLIDIN-3-YL]PENTANOATE
Authors:Tan, J., Anand, K., Mesters, J.R., Hilgenfeld, R.
Deposit date:2011-08-31
Release date:2012-09-19
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Peptidic Alpha, Beta-Unsaturated Ethyl Esters as Inhibitors of the 3C Protease of Coxsackie Virus B3: Crystal Structures, Antiviral Activities, and Resistance Mutations
To be Published
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