Author results

2BKK
  • Download 2bkk
  • View 2bkk
Molmil generated image of 2bkk
CRYSTAL STRUCTURE OF AMINOGLYCOSIDE PHOSPHOTRANSFERASE APH(3')-IIIA IN COMPLEX WITH THE INHIBITOR AR_3A
Descriptor:AMINOGLYCOSIDE 3'-PHOSPHOTRANSFERASE, DESIGNED ANKYRIN REPEAT INHIBITOR AR_3A, ADENOSINE-5'-DIPHOSPHATE, ...
Authors:Kohl, A., Amstutz, P., Parizek, P., Binz, H.K., Briand, C., Capitani, G., Forrer, P., Pluckthun, A., Grutter, M.G.
Deposit date:2005-02-16
Release date:2005-08-09
Last modified:2016-12-21
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:Allosteric Inhibition of Aminoglycoside Phosphotransferase by a Designed Ankyrin Repeat Protein
Structure, 13, 2005
1SVX
  • Download 1svx
  • View 1svx
Molmil generated image of 1svx
CRYSTAL STRUCTURE OF A DESIGNED SELECTED ANKYRIN REPEAT PROTEIN IN COMPLEX WITH THE MALTOSE BINDING PROTEIN
Descriptor:Ankyrin Repeat Protein off7, Maltose-binding periplasmic protein
Authors:Binz, H.K., Amstutz, P., Kohl, A., Stumpp, M.T., Briand, C., Forrer, P., Gruetter, M.G., Plueckthun, A.
Deposit date:2004-03-30
Release date:2004-05-25
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.24 Å)
Cite:High-affinity binders selected from designed ankyrin repeat protein libraries
NAT.BIOTECHNOL., 22, 2004
2V5Q
  • Download 2v5q
  • View 2v5q
Molmil generated image of 2v5q
CRYSTAL STRUCTURE OF WILD-TYPE PLK-1 KINASE DOMAIN IN COMPLEX WITH A SELECTIVE DARPIN
Descriptor:SERINE/THREONINE-PROTEIN KINASE PLK1, DESIGN ANKYRIN REPEAT PROTEIN
Authors:Bandeiras, T.M., Hillig, R.C., Matias, P.M., Eberspaecher, U., Fanghaenel, J., Thomaz, M., Miranda, S., Crusius, K., Puetter, V., Amstutz, P., Gulotti-Georgieva, M., Binz, H.K., Holz, C., Schmitz, A.A.P., Lang, C., Donner, P., Egner, U., Carrondo, M.A., Mueller-Tiemann, B.
Deposit date:2007-07-08
Release date:2008-04-01
Last modified:2019-02-20
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structure of wild-type Plk-1 kinase domain in complex with a selective DARPin.
Acta Crystallogr. D Biol. Crystallogr., 64, 2008
1P4B
  • Download 1p4b
  • View 1p4b
Molmil generated image of 1p4b
THREE-DIMENSIONAL STRUCTURE OF A SINGLE CHAIN FV FRAGMENT COMPLEXED WITH THE PEPTIDE GCN4(7P-14P).
Descriptor:Antibody Variable light chain, Antibody Variable heavy chain, GCN4(7P-14P) peptide
Authors:Zahnd, C., Spinelli, S., Luginbuhl, B., Jermutus, L., Amstutz, P., Cambillau, C., Pluckthun, A.
Deposit date:2003-04-22
Release date:2004-05-04
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.35 Å)
Cite:Directed in Vitro Evolution and Crystallographic Analysis of a Peptide-binding Single Chain Antibody Fragment (scFv) with Low Picomolar Affinity.
J.Biol.Chem., 279, 2004
1P4I
  • Download 1p4i
  • View 1p4i
Molmil generated image of 1p4i
CRYSTAL STRUCTURE OF SCFV AGAINST PEPTIDE GCN4
Descriptor:ANTIBODY VARIABLE LIGHT CHAIN, antibody variable heavy chain
Authors:Zahnd, C., Spinelli, S., Luginbuhl, B., Jermutus, L., Amstutz, P., Cambillau, C., Pluckthun, A.
Deposit date:2003-04-23
Release date:2004-05-04
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Directed in Vitro Evolution and Crystallographic Analysis of a Peptide-binding Single Chain Antibody Fragment (scFv) with Low Picomolar Affinity.
J.Biol.Chem., 279, 2004
2J8S
  • Download 2j8s
  • View 2j8s
Molmil generated image of 2j8s
DRUG EXPORT PATHWAY OF MULTIDRUG EXPORTER ACRB REVEALED BY DARPIN INHIBITORS
Descriptor:ACRIFLAVINE RESISTANCE PROTEIN B, DARPIN, DODECYL-BETA-D-MALTOSIDE, ...
Authors:Sennhauser, G., Amstutz, P., Briand, C., Storchenegger, O., Gruetter, M.G.
Deposit date:2006-10-27
Release date:2007-01-23
Last modified:2016-12-21
Method:X-RAY DIFFRACTION (2.54 Å)
Cite:Drug Export Pathway of Multidrug Exporter Acrb Revealed by Darpin Inhibitors.
Plos Biol., 5, 2007
2P2C
  • Download 2p2c
  • View 2p2c
Molmil generated image of 2p2c
INHIBITION OF CASPASE-2 BY A DESIGNED ANKYRIN REPEAT PROTEIN (DARPIN)
Descriptor:Caspase-2
Authors:Roschitzki Voser, H., Briand, C., Capitani, G., Gruetter, M.G.
Deposit date:2007-03-07
Release date:2007-05-22
Last modified:2018-01-24
Method:X-RAY DIFFRACTION (3.24 Å)
Cite:Inhibition of Caspase-2 by a Designed Ankyrin Repeat Protein: Specificity, Structure, and Inhibition Mechanism.
Structure, 15, 2007