Author results

1S8G
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CRYSTAL STRUCTURE OF LYS49-PHOSPHOLIPASE A2 FROM AGKISTRODON CONTORTRIX LATICINCTUS, FATTY ACID BOUND FORM
Descriptor:Phospholipase A2 homolog, SULFATE ION, LAURIC ACID, ...
Authors:Ambrosio, A.L.B., de Souza, D.H.F., Nonato, M.C., Selistre de Araujo, H.S., Ownby, C.L., Garratt, R.C.
Deposit date:2004-02-02
Release date:2004-02-10
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:A Molecular Mechanism for Lys49-Phospholipase A2 Activity Based on Ligand-induced Conformational Change.
J.Biol.Chem., 280, 2005
1S8H
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CRYSTAL STRUCTURE OF LYS49-PHOSPHOLIPASE A2 FROM AGKISTRODON CONTORTRIX LATICINCTUS, FIRST FATTY ACID FREE FORM
Descriptor:Phospholipase A2 homolog, SULFATE ION
Authors:Ambrosio, A.L.B., de Souza, D.H.F., Nonato, M.C., Selistre de Araujo, H.S., Ownby, C.L., Garratt, R.C.
Deposit date:2004-02-02
Release date:2004-02-10
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:A Molecular Mechanism for Lys49-Phospholipase A2 Activity Based on Ligand-induced Conformational Change.
J.Biol.Chem., 280, 2005
1S8I
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CRYSTAL STRUCTURE OF LYS49-PHOSPHOLIPASE A2 FROM AGKISTRODON CONTORTRIX LATICINCTUS, SECOND FATTY ACID FREE FORM
Descriptor:Phospholipase A2 homolog, SULFATE ION
Authors:Ambrosio, A.L.B., de Souza, D.H.F., Nonato, M.C., Selistre de Araujo, H.S., Ownby, C.L., Garratt, R.C.
Deposit date:2004-02-02
Release date:2004-02-10
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.609 Å)
Cite:A Molecular Mechanism for Lys49-Phospholipase A2 Activity Based on Ligand-induced Conformational Change.
J.Biol.Chem., 280, 2005
2OM9
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AJULEMIC ACID, A SYNTHETIC CANNABINOID BOUND TO PPAR GAMMA
Descriptor:Peroxisome proliferator-activated receptor gamma, (6AR,10AR)-3-(1,1-DIMETHYLHEPTYL)-1-HYDROXY-6,6-DIMETHYL-6A,7,10,10A-TETRAHYDRO-6H-BENZO[C]CHROMENE-9-CARBOXYLIC ACID
Authors:Ambrosio, A.L.B., Garratt, R.C.
Deposit date:2007-01-21
Release date:2007-04-24
Last modified:2018-06-13
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Ajulemic Acid, a Synthetic Nonpsychoactive Cannabinoid Acid, Bound to the Ligand Binding Domain of the Human Peroxisome Proliferator-activated Receptor gamma
J.Biol.Chem., 282, 2007
2H77
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CRYSTAL STRUCTURE OF HUMAN TR ALPHA BOUND T3 IN MONOCLINIC SPACE GROUP
Descriptor:THRA protein, 3,5,3'TRIIODOTHYRONINE
Authors:Nascimento, A.S., Dias, S.M.G., Nunes, F.M., Aparicio, R., Bleicher, L., Ambrosio, A.L.B., Figueira, A.C.M., Santos, M.A.M., Neto, M.O., Fischer, H., Togashi, H.F.M., Craievich, A.F., Garrat, R.C., Baxter, J.D., Webb, P., Polikarpov, I.
Deposit date:2006-06-01
Release date:2006-07-25
Last modified:2017-10-18
Method:X-RAY DIFFRACTION (2.33 Å)
Cite:Structural rearrangements in the thyroid hormone receptor hinge domain and their putative role in the receptor function.
J.Mol.Biol., 360, 2006
2H79
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CRYSTAL STRUCTURE OF HUMAN TR ALPHA BOUND T3 IN ORTHORHOMBIC SPACE GROUP
Descriptor:THRA protein, 3,5,3'TRIIODOTHYRONINE
Authors:Nascimento, A.S., Dias, S.M.G., Nunes, F.M., Aparicio, R., Bleicher, L., Ambrosio, A.L.B., Figueira, A.C.M., Santos, M.A.M., Neto, M.O., Fischer, H., Togashi, H.F.M., Craievich, A.F., Garrat, R.C., Baxter, J.D., Webb, P., Polikarpov, I.
Deposit date:2006-06-01
Release date:2006-07-25
Last modified:2018-01-24
Method:X-RAY DIFFRACTION (1.87 Å)
Cite:Structural rearrangements in the thyroid hormone receptor hinge domain and their putative role in the receptor function.
J.Mol.Biol., 360, 2006
4BQM
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CRYSTAL STRUCTURE OF HUMAN LIVER-TYPE GLUTAMINASE, CATALYTIC DOMAIN
Descriptor:GLUTAMINASE LIVER ISOFORM, MITOCHONDRIAL, 1,2-ETHANEDIOL, ...
Authors:Ferreira, I.M., Vollmar, M., Krojer, T., Strain-Damerell, C., Froese, S., Coutandin, D., Williams, E., Burgess-Brown, N., von Delft, F., Arrowsmith, C.H., Bountra, C., Edwards, A., Dias, S.M.G., Ambrosio, A.L.B., Yue, W.W.
Deposit date:2013-05-31
Release date:2013-07-10
Last modified:2018-01-24
Method:X-RAY DIFFRACTION (2.18 Å)
Cite:Crystal Structure of Human Liver-Type Glutaminase, Catalytic Domain
To be Published
5F28
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CRYSTAL STRUCTURE OF FAT DOMAIN OF FOCAL ADHESION KINASE (FAK) BOUND TO THE TRANSCRIPTION FACTOR MEF2C
Descriptor:MEF2C, Focal adhesion kinase 1
Authors:Cardoso, A.C., Ambrosio, A.L.B., Dessen, A., Franchini, K.G.
Deposit date:2015-12-01
Release date:2016-07-13
Last modified:2019-04-17
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:FAK Forms a Complex with MEF2 to Couple Biomechanical Signaling to Transcription in Cardiomyocytes.
Structure, 24, 2016
5U0I
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C-TERMINAL ANKYRIN REPEATS FROM HUMAN KIDNEY-TYPE GLUTAMINASE (KGA) - TETRAGONAL CRYSTAL FORM
Descriptor:Glutaminase kidney isoform, mitochondrial, CHLORIDE ION, ...
Authors:Pasquali, C.C., Gonzalez, A., Dias, S.M.G., Ambrosio, A.L.B.
Deposit date:2016-11-24
Release date:2017-05-24
Last modified:2019-04-17
Method:X-RAY DIFFRACTION (1.423 Å)
Cite:The origin and evolution of human glutaminases and their atypical C-terminal ankyrin repeats.
J. Biol. Chem., 292, 2017
5U0J
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C-TERMINAL ANKYRIN REPEATS FROM HUMAN KIDNEY-TYPE GLUTAMINASE (KGA) - MONOCLINIC CRYSTAL FORM
Descriptor:Glutaminase kidney isoform, mitochondrial, SODIUM ION
Authors:Pasquali, C.C., Gonzalez, A., Dias, S.M.G., Ambrosio, A.L.B.
Deposit date:2016-11-24
Release date:2017-05-24
Last modified:2019-04-17
Method:X-RAY DIFFRACTION (1.72 Å)
Cite:The origin and evolution of human glutaminases and their atypical C-terminal ankyrin repeats.
J. Biol. Chem., 292, 2017
5U0K
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C-TERMINAL ANKYRIN REPEATS FROM HUMAN LIVER-TYPE GLUTAMINASE (GAB/LGA)
Descriptor:Glutaminase liver isoform, mitochondrial
Authors:Ferreira, I.M., Pasquali, C.C., Gonzalez, A., Dias, S.M.G., Ambrosio, A.L.B.
Deposit date:2016-11-24
Release date:2017-05-24
Last modified:2019-04-17
Method:X-RAY DIFFRACTION (2.548 Å)
Cite:The origin and evolution of human glutaminases and their atypical C-terminal ankyrin repeats.
J. Biol. Chem., 292, 2017
5UQE
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MULTIDOMAIN STRUCTURE OF HUMAN KIDNEY-TYPE GLUTAMINASE(KGA/GLS)
Descriptor:Glutaminase kidney isoform, mitochondrial, N,N'-[sulfanediylbis(ethane-2,1-diyl-1,3,4-thiadiazole-5,2-diyl)]bis(2-phenylacetamide)
Authors:Pasquali, C.C., Dias, S.M.G., Ambrosio, A.L.B.
Deposit date:2017-02-08
Release date:2017-05-24
Last modified:2019-04-17
Method:X-RAY DIFFRACTION (3.6 Å)
Cite:The origin and evolution of human glutaminases and their atypical C-terminal ankyrin repeats.
J. Biol. Chem., 292, 2017
3SS3
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CRYSTAL STRUCTURE OF MOUSE GLUTAMINASE C, LIGAND-FREE FORM
Descriptor:Glutaminase C, CHLORIDE ION
Authors:Ambrosio, A.L.B., Dias, S.M.G., Cerione, R.A.
Deposit date:2011-07-07
Release date:2012-01-11
Last modified:2012-04-04
Method:X-RAY DIFFRACTION (2.42 Å)
Cite:Mitochondrial localization and structure-based phosphate activation mechanism of Glutaminase C with implications for cancer metabolism.
Proc.Natl.Acad.Sci.USA, 109, 2012
3SS4
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CRYSTAL STRUCTURE OF MOUSE GLUTAMINASE C, PHOSPHATE-BOUND FORM
Descriptor:Glutaminase C, PHOSPHATE ION
Authors:Ambrosio, A.L.B., Dias, S.M.G., Cerione, R.A.
Deposit date:2011-07-07
Release date:2012-01-11
Last modified:2012-04-04
Method:X-RAY DIFFRACTION (2.85 Å)
Cite:Mitochondrial localization and structure-based phosphate activation mechanism of Glutaminase C with implications for cancer metabolism.
Proc.Natl.Acad.Sci.USA, 109, 2012
3SS5
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CRYSTAL STRUCTURE OF MOUSE GLUTAMINASE C, L-GLUTAMATE-BOUND FORM
Descriptor:Glutaminase C, GLUTAMIC ACID
Authors:Ambrosio, A.L.B., Dias, S.M.G., Cerione, R.A.
Deposit date:2011-07-07
Release date:2012-01-11
Last modified:2017-11-08
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Mitochondrial localization and structure-based phosphate activation mechanism of Glutaminase C with implications for cancer metabolism.
Proc.Natl.Acad.Sci.USA, 109, 2012
3FEX
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CRYSTAL STRUCTURE OF THE CBC-IMPORTIN ALPHA COMPLEX.
Descriptor:Nuclear cap-binding protein subunit 1, Nuclear cap-binding protein subunit 2, Importin subunit alpha-2
Authors:Dias, S.M.G., Ambrosio, A.L.B., Cerione, R.A.
Deposit date:2008-12-01
Release date:2009-08-11
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3.549 Å)
Cite:The molecular basis for the regulation of the cap-binding complex by the importins.
Nat.Struct.Mol.Biol., 16, 2009
3FEY
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CRYSTAL STRUCTURE OF THE CBC-IMPORTIN ALPHA COMPLEX.
Descriptor:Nuclear cap-binding protein subunit 1, Nuclear cap-binding protein subunit 2, Importin subunit alpha-2
Authors:Dias, S.M.G., Ambrosio, A.L.B., Cerione, R.A.
Deposit date:2008-12-01
Release date:2009-08-11
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:The molecular basis for the regulation of the cap-binding complex by the importins.
Nat.Struct.Mol.Biol., 16, 2009
3ST1
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CRYSTAL STRUCTURE OF NECROSIS AND ETHYLENE INDUCING PROTEIN 2 FROM THE CAUSAL AGENT OF COCOA'S WITCHES BROOM DISEASE
Descriptor:Necrosis-and ethylene-inducing protein, ZINC ION, SODIUM ION
Authors:Oliveira, J.F., Zaparoli, G., Barsottini, M.R.O., Ambrosio, A.L.B., Pereira, G.A.G., Dias, S.M.G.
Deposit date:2011-07-08
Release date:2011-11-02
Last modified:2017-11-08
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:The Crystal Structure of Necrosis- and Ethylene-Inducing Protein 2 from the Causal Agent of Cacao's Witches' Broom Disease Reveals Key Elements for Its Activity.
Biochemistry, 50, 2011
3SUJ
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CRYSTAL STRUCTURE OF CERATO-PLATANIN 1 FROM M. PERNICIOSA (MPCP1)
Descriptor:Cerato-platanin 1, ACETATE ION, ZINC ION, ...
Authors:Oliveira, J.F., Barsottini, M.R.O., Zaparoli, G., Machado, L.O., Dias, S.M.G., Pereira, G.A.G., Ambrosio, A.L.B.
Deposit date:2011-07-11
Release date:2012-07-11
Last modified:2019-02-06
Method:X-RAY DIFFRACTION (1.34 Å)
Cite:Functional diversification of cerato-platanins in Moniliophthora perniciosa as seen by differential expression and protein function specialization.
Mol. Plant Microbe Interact., 26, 2013
3SUK
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CRYSTAL STRUCTURE OF CERATO-PLATANIN 2 FROM M. PERNICIOSA (MPCP2)
Descriptor:Cerato-platanin-like protein
Authors:Oliveira, J.F., Barsottini, M.R.O., Zaparoli, G., Machado, L.O., Dias, S.M.G., Pereira, G.A.G., Ambrosio, A.L.B.
Deposit date:2011-07-11
Release date:2012-07-11
Last modified:2019-02-06
Method:X-RAY DIFFRACTION (1.34 Å)
Cite:Functional diversification of cerato-platanins in Moniliophthora perniciosa as seen by differential expression and protein function specialization.
Mol. Plant Microbe Interact., 26, 2013
3SUL
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CRYSTAL STRUCTURE OF CERATO-PLATANIN 3 FROM M. PERNICIOSA (MPCP3)
Descriptor:Cerato-platanin-like protein
Authors:Oliveira, J.F., Barsottini, M.R.O., Zaparoli, G., Machado, L.O., Dias, S.M.G., Pereira, G.A.G., Ambrosio, A.L.B.
Deposit date:2011-07-11
Release date:2012-07-11
Last modified:2019-02-06
Method:X-RAY DIFFRACTION (1.63 Å)
Cite:Functional diversification of cerato-platanins in Moniliophthora perniciosa as seen by differential expression and protein function specialization.
Mol. Plant Microbe Interact., 26, 2013
3SUM
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CRYSTAL STRUCTURE OF CERATO-PLATANIN 5 FROM M. PERNICIOSA (MPCP5)
Descriptor:Cerato-platanin-like protein
Authors:Oliveira, J.F., Barsottini, M.R.O., Zaparoli, G., Machado, L.O., Dias, S.M.G., Pereira, G.A.G., Ambrosio, A.L.B.
Deposit date:2011-07-11
Release date:2012-07-11
Last modified:2019-02-06
Method:X-RAY DIFFRACTION (1.87 Å)
Cite:Functional diversification of cerato-platanins in Moniliophthora perniciosa as seen by differential expression and protein function specialization.
Mol. Plant Microbe Interact., 26, 2013
4JJM
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STRUCTURE OF A CYCLOPHILIN FROM CITRUS SINENSIS (CSCYP) IN COMPLEX WITH CYCLOSPORIN A
Descriptor:Peptidyl-prolyl cis-trans isomerase, cyclosporin A
Authors:Campos, B.M., Ambrosio, A.L.B., Souza, T.A.C.B., Barbosa, J.A.R.G., Benedetti, C.E.
Deposit date:2013-03-08
Release date:2013-06-12
Last modified:2018-12-05
Method:X-RAY DIFFRACTION (2.09 Å)
Cite:A redox 2-cys mechanism regulates the catalytic activity of divergent cyclophilins.
Plant Physiol., 162, 2013
4JKT
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CRYSTAL STRUCTURE OF MOUSE GLUTAMINASE C, BPTES-BOUND FORM
Descriptor:Glutaminase kidney isoform, mitochondrial, N,N'-[sulfanediylbis(ethane-2,1-diyl-1,3,4-thiadiazole-5,2-diyl)]bis(2-phenylacetamide)
Authors:Fornezari, C., Ferreira, A.P.S., Dias, S.M.G., Ambrosio, A.L.B.
Deposit date:2013-03-11
Release date:2013-08-14
Last modified:2017-11-15
Method:X-RAY DIFFRACTION (2.77 Å)
Cite:Active Glutaminase C Self-assembles into a Supratetrameric Oligomer That Can Be Disrupted by an Allosteric Inhibitor.
J.Biol.Chem., 288, 2013
4WN5
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CRYSTAL STRUCTURE OF THE C-TERMINAL PER-ARNT-SIM (PASB) OF HUMAN HIF-3ALPHA9 BOUND TO 18:1-1-MONOACYLGLYCEROL
Descriptor:Hypoxia-inducible factor 3-alpha, SULFATE ION, MONOVACCENIN, ...
Authors:Fala, A.M., Oliveira, J.F., Dias, S.M., Ambrosio, A.L.
Deposit date:2014-10-10
Release date:2015-08-05
Last modified:2019-04-17
Method:X-RAY DIFFRACTION (1.15 Å)
Cite:Unsaturated fatty acids as high-affinity ligands of the C-terminal Per-ARNT-Sim domain from the Hypoxia-inducible factor 3alpha
Sci.Rep., 5, 2015
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