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6NNQ
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BU of 6nnq by Molmil
Non-covalent structure of SENP1 in complex with SUMO2
Descriptor: Sentrin-specific protease 1, Small ubiquitin-related modifier 3
Authors:Ambaye, N.D.
Deposit date:2019-01-15
Release date:2019-05-08
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (2.621 Å)
Cite:Noncovalent structure of SENP1 in complex with SUMO2.
Acta Crystallogr.,Sect.F, 75, 2019
5EEQ
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BU of 5eeq by Molmil
Grb7 SH2 with the G7-B1 bicyclic peptide inhibitor
Descriptor: Bicyclic Peptide Inhibitor, Growth factor receptor-bound protein 7, PHOSPHATE ION
Authors:Ambaye, N.D, Watson, G.M, Wilce, M.C.J, Wilce, G.M.
Deposit date:2015-10-23
Release date:2016-06-15
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Unexpected involvement of staple leads to redesign of selective bicyclic peptide inhibitor of Grb7.
Sci Rep, 6, 2016
4WWQ
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BU of 4wwq by Molmil
Apo structure of the Grb7 SH2 domain
Descriptor: Growth factor receptor-bound protein 7, MALONIC ACID
Authors:Watson, G.M, Ambaye, N.D, Wilce, M.C, Wilce, J.A.
Deposit date:2014-11-12
Release date:2015-09-23
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Cyclic Peptides Incorporating Phosphotyrosine Mimetics as Potent and Specific Inhibitors of the Grb7 Breast Cancer Target.
J.Med.Chem., 58, 2015
4Y1L
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BU of 4y1l by Molmil
Ubc9 Homodimer The Missing Link in Poly-SUMO Chain Formation
Descriptor: RWD domain-containing protein 3, SUMO-conjugating enzyme UBC9
Authors:Aileen, Y.A, Ambaye, N.D, Li, Y.J, Vega, R, Bzymek, K, Williams, J.C, Hu, W, Chen, Y.
Deposit date:2015-02-08
Release date:2015-05-06
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:RWD Domain as an E2 (Ubc9)-Interaction Module.
J.Biol.Chem., 290, 2015
3PQZ
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BU of 3pqz by Molmil
Grb7 SH2 with peptide
Descriptor: Growth factor receptor-bound protein 7, cyclic peptide
Authors:Wilce, J.A.
Deposit date:2010-11-29
Release date:2011-07-20
Last modified:2011-09-21
Method:X-RAY DIFFRACTION (2.413 Å)
Cite:Structural basis of binding by cyclic nonphosphorylated Peptide antagonists of grb7 implicated in breast cancer progression
J.Mol.Biol., 412, 2011
4X6S
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BU of 4x6s by Molmil
Grb7 SH2 domain with phosphotyrosine mimetic inhibitor peptide
Descriptor: Growth factor receptor-bound protein 7, Phosphotyrosine mimetic inhibitor peptide G7-TEM1
Authors:Watson, G.M, Panjikar, S, Wilce, M.C, Wilce, J.A.
Deposit date:2014-12-09
Release date:2015-09-23
Last modified:2015-10-28
Method:X-RAY DIFFRACTION (2.55 Å)
Cite:Cyclic Peptides Incorporating Phosphotyrosine Mimetics as Potent and Specific Inhibitors of the Grb7 Breast Cancer Target.
J.Med.Chem., 58, 2015
5D0J
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BU of 5d0j by Molmil
Grb7 SH2 with inhibitor peptide
Descriptor: G7-TEdFP peptide, Growth factor receptor-bound protein 7, PHOSPHATE ION
Authors:Gunzburg, M.J, Watson, G.M, Wilce, J.A, Wilce, M.C.J.
Deposit date:2015-08-03
Release date:2016-06-15
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Unexpected involvement of staple leads to redesign of selective bicyclic peptide inhibitor of Grb7.
Sci Rep, 6, 2016
5EEL
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BU of 5eel by Molmil
Grb7 SH2 with bicyclic peptide inhibitor
Descriptor: Bicyclic Peptide Inhibitor, FORMIC ACID, Growth factor receptor-bound protein 7, ...
Authors:Watson, G.M, Gunzburg, M.J, Wilce, M.C.J, Wilce, J.A.
Deposit date:2015-10-23
Release date:2016-06-15
Last modified:2018-12-26
Method:X-RAY DIFFRACTION (2.47 Å)
Cite:Unexpected involvement of staple leads to redesign of selective bicyclic peptide inhibitor of Grb7.
Sci Rep, 6, 2016

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PDB entries from 2024-03-27

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