Author results

1OV6
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M64V PNP + ALLO
Descriptor:Purine nucleoside phosphorylase, PHOSPHATE ION, 9-(6-DEOXY-BETA-D-ALLOFURANOSYL)-6-METHYLPURINE
Authors:Ealick, S.E., Bennett, E.M., Anand, R., Secrist, J.A., Parker, P.W., Hassan, A.E., Allan, P.W., McPherson, D.T., Sorscher, E.J.
Deposit date:2003-03-25
Release date:2004-02-17
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Designer gene therapy using an Escherichia coli purine nucleoside phosphorylase/prodrug system.
Chem.Biol., 10, 2003
1OVG
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M64V PNP +MEPDR
Descriptor:Purine nucleoside phosphorylase, PHOSPHATE ION, 9-(2-DEOXY-BETA-D-RIBOFURANOSYL)-6-METHYLPURINE
Authors:Ealick, S.E., Bennett, E.M., Anand, R., Secrist, J.A., Parker, P.W., Hassan, A.E., Allan, P.W., McPherson, D.T., Sorscher, E.J.
Deposit date:2003-03-26
Release date:2004-02-17
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Designer gene therapy using an Escherichia coli purine nucleoside phosphorylase/prodrug system.
Chem.Biol., 10, 2003
1OTX
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PURINE NUCLEOSIDE PHOSPHORYLASE M64V MUTANT
Descriptor:Purine nucleoside phosphorylase, PHOSPHATE ION
Authors:Ealick, S.E., Bennett, E.M., Anand, R., Secrist, J.A., Parker, W.B., Hassan, A.E., Allan, P.W., McPherson, D.T., Sorscher, E.J.
Deposit date:2003-03-23
Release date:2004-02-17
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Designer gene therapy using an Escherichia coli purine nucleoside phosphorylase/prodrug system.
Chem.Biol., 10, 2003
1OTY
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NATIVE PNP +ALLO
Descriptor:Purine nucleoside phosphorylase, PHOSPHATE ION, 6-METHYLPURINE
Authors:Ealick, S.E., Bennett, E.M., Anand, R., Secrist, J.A., Parker, W.B., Hassan, A.E., Allan, P.W., McPherson, D.T., Sorscher, E.J.
Deposit date:2003-03-23
Release date:2004-02-17
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Designer gene therapy using an Escherichia coli purine nucleoside phosphorylase/prodrug system.
Chem.Biol., 10, 2003
1OU4
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NATIVE PNP +TALO
Descriptor:Purine nucleoside phosphorylase, PHOSPHATE ION, 6-METHYLPURINE
Authors:Ealick, S.E., Bennett, E.M., Anand, R., Secrist, J.A., Parker, W.B., Hassan, A.E., Allan, P.W., McPherson, D.T., Sorscher, E.J.
Deposit date:2003-03-24
Release date:2004-02-17
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Designer gene therapy using an Escherichia coli purine nucleoside phosphorylase/prodrug system.
Chem.Biol., 10, 2003
1OUM
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M64V PNP +TALO
Descriptor:Purine nucleoside phosphorylase, 9-(6-DEOXY-ALPHA-L-TALOFURANOSYL)-6-METHYLPURINE, PHOSPHATE ION
Authors:Ealick, S.E., Bennett, E.M., Anand, R., Secrist, J.A., Parker, W.B., Hassan, A.E., Allan, P.W., McPherson, D.T., Sorscher, E.J.
Deposit date:2003-03-24
Release date:2004-02-17
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Designer gene therapy using an Escherichia coli purine nucleoside phosphorylase/prodrug system.
Chem.Biol., 10, 2003
1PK7
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CRYSTAL STRUCTURE OF E. COLI PURINE NUCLEOSIDE PHOSPHORYLASE COMPLEXED WITH ADENOSINE AND SULFATE/PHOSPHATE
Descriptor:Purine nucleoside phosphorylase, PHOSPHATE ION, ADENOSINE
Authors:Bennett, E.M., Li, C., Allan, P.W., Parker, W.B., Ealick, S.E.
Deposit date:2003-06-05
Release date:2003-11-25
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structural basis for substrate specificity of Escherichia coli purine nucleoside phosphorylase.
J.Biol.Chem., 278, 2003
1PK9
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CRYSTAL STRUCTURE OF E. COLI PURINE NUCLEOSIDE PHOSPHORYLASE COMPLEXED WITH 2-FLUOROADENOSINE AND SULFATE/PHOSPHATE
Descriptor:Purine nucleoside phosphorylase, PHOSPHATE ION, 2-(6-AMINO-2-FLUORO-PURIN-9-YL)-5-HYDROXYMETHYL-TETRAHYDRO-FURAN-3,4-DIOL
Authors:Bennett, E.M., Li, C., Allan, P.W., Parker, W.B., Ealick, S.E.
Deposit date:2003-06-05
Release date:2003-11-25
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structural basis for substrate specificity of Escherichia coli purine nucleoside phosphorylase.
J.Biol.Chem., 278, 2003
1PKE
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CRYSTAL STRUCTURE OF E. COLI PURINE NUCLEOSIDE PHOSPHORYLASE COMPLEXED WITH 2-FLUORO-2'-DEOXYADENOSINE AND SULFATE/PHOSPHATE
Descriptor:Purine nucleoside phosphorylase, PHOSPHATE ION, 5-(6-AMINO-2-FLUORO-PURIN-9-YL)-2-HYDROXYMETHYL-TETRAHYDRO-FURAN-3-OL
Authors:Bennett, E.M., Li, C., Allan, P.W., Parker, W.B., Ealick, S.E.
Deposit date:2003-06-05
Release date:2003-11-25
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structural basis for substrate specificity of Escherichia coli purine nucleoside phosphorylase.
J.Biol.Chem., 278, 2003
1PR0
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ESCHERICHIA COLI PURINE NUCLEOSIDE PHOSPHORYLASE COMPLEXED WITH INOSINE AND PHOSPHATE/SULFATE
Descriptor:Purine nucleoside phosphorylase, PHOSPHATE ION, INOSINE
Authors:Bennett, E.M., Li, C., Allan, P.W., Parker, W.B., Ealick, S.E.
Deposit date:2003-06-19
Release date:2003-11-25
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structural basis for substrate specificity of Escherichia coli purine nucleoside phosphorylase.
J.Biol.Chem., 278, 2003
1PR1
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ESCHERICHIA COLI PURINE NUCLEOSIDE PHOSPHORYLASE COMPLEXED WITH FORMYCIN B AND PHOSPHATE/SULFATE
Descriptor:Purine nucleoside phosphorylase, PHOSPHATE ION, FORMYCIN B
Authors:Bennett, E.M., Li, C., Allan, P.W., Parker, W.B., Ealick, S.E.
Deposit date:2003-06-19
Release date:2003-11-25
Last modified:2018-08-08
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structural basis for substrate specificity of Escherichia coli purine nucleoside phosphorylase.
J.Biol.Chem., 278, 2003
1PR2
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ESCHERICHIA COLI PURINE NUCLEOSIDE PHOSPHORYLASE COMPLEXED WITH 9-BETA-D-[2-DEOXYRIBOFURANOSYL]-6-METHYLPURINE AND PHOSPHATE/SULFATE
Descriptor:Purine nucleoside phosphorylase, PHOSPHATE ION, 9-(2-DEOXY-BETA-D-RIBOFURANOSYL)-6-METHYLPURINE
Authors:Bennett, E.M., Li, C., Allan, P.W., Parker, W.B., Ealick, S.E.
Deposit date:2003-06-19
Release date:2003-11-25
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structural basis for substrate specificity of Escherichia coli purine nucleoside phosphorylase.
J.Biol.Chem., 278, 2003
1PR4
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ESCHERICHIA COLI PURINE NUCLEOSIDE PHOSPHORYLASE COMPLEXED WITH 9-BETA-D-RIBOFURANOSYL-6-METHYLTHIOPURINE AND PHOSPHATE/SULFATE
Descriptor:Purine nucleoside phosphorylase, PHOSPHATE ION, 2-HYDROXYMETHYL-5-(6-METHYLSULFANYL-PURIN-9-YL)-TETRAHYDRO-FURAN-3,4-DIOL
Authors:Bennett, E.M., Li, C., Allan, P.W., Parker, W.B., Ealick, S.E.
Deposit date:2003-06-19
Release date:2003-11-25
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Structural basis for substrate specificity of Escherichia coli purine nucleoside phosphorylase.
J.Biol.Chem., 278, 2003
1PR5
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ESCHERICHIA COLI PURINE NUCLEOSIDE PHOSPHORYLASE COMPLEXED WITH 7-DEAZAADENOSINE AND PHOSPHATE/SULFATE
Descriptor:Purine nucleoside phosphorylase, PHOSPHATE ION, '2-(4-AMINO-PYRROLO[2,3-D]PYRIMIDIN-7-YL)-5-HYDROXYMETHYL-TETRAHYDRO-FURAN-3,4-DIOL
Authors:Bennett, E.M., Li, C., Allan, P.W., Parker, W.B., Ealick, S.E.
Deposit date:2003-06-19
Release date:2003-11-25
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structural basis for substrate specificity of Escherichia coli purine nucleoside phosphorylase.
J.Biol.Chem., 278, 2003
1PR6
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ESCHERICHIA COLI PURINE NUCLEOSIDE PHOSPHORYLASE COMPLEXED WITH 9-BETA-D-XYLOFURANOSYLADENINE AND PHOSPHATE/SULFATE
Descriptor:Purine nucleoside phosphorylase, PHOSPHATE ION, 2-(6-AMINO-OCTAHYDRO-PURIN-9-YL)-5-HYDROXYMETHYL-TETRAHYDRO-FURAN-3,4-DIOL
Authors:Bennett, E.M., Li, C., Allan, P.W., Parker, W.B., Ealick, S.E.
Deposit date:2003-06-19
Release date:2003-11-25
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structural basis for substrate specificity of Escherichia coli purine nucleoside phosphorylase.
J.Biol.Chem., 278, 2003
1PW7
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CRYSTAL STRUCTURE OF E. COLI PURINE NUCLEOSIDE PHOSPHORYLASE COMPLEXED WITH 9-BETA-D-ARABINOFURANOSYLADENINE AND SULFATE/PHOSPHATE
Descriptor:Purine nucleoside phosphorylase, PHOSPHATE ION, 2-(6-AMINO-PURIN-9-YL)-5-HYDROXYMETHYL-TETRAHYDRO-FURAN-3,4-DIOL
Authors:Bennett, E.M., Li, C., Allan, P.W., Parker, W.B., Ealick, S.E.
Deposit date:2003-06-30
Release date:2003-11-25
Last modified:2011-11-16
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural basis for substrate specificity of Escherichia coli purine nucleoside phosphorylase.
J.Biol.Chem., 278, 2003
3KHS
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CRYSTAL STRUCTURE OF GROUPER IRIDOVIRUS PURINE NUCLEOSIDE PHOSPHORYLASE
Descriptor:Purine nucleoside phosphorylase, PHOSPHATE ION, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL
Authors:Kang, Y.N., Zhang, Y., Allan, P.W., Parker, W.B., Ting, J.W., Chang, C.Y., Ealick, S.E.
Deposit date:2009-10-30
Release date:2010-02-16
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.38 Å)
Cite:Structure of grouper iridovirus purine nucleoside phosphorylase
Acta Crystallogr.,Sect.D, 66, 2010
3QPB
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CRYSTAL STRUCTURE OF STREPTOCOCCUS PYOGENES URIDINE PHOSPHORYLASE REVEALS A SUBCLASS OF THE NP-I SUPERFAMILY
Descriptor:Uridine phosphorylase, RIBOSE-1-PHOSPHATE, URACIL
Authors:Tran, T.H., Christoffersen, S., Parker, W.B., Piskur, J., Serra, I., Terreni, M., Ealick, S.E.
Deposit date:2011-02-11
Release date:2011-08-24
Method:X-RAY DIFFRACTION (1.82 Å)
Cite:The Crystal Structure of Streptococcus pyogenes Uridine Phosphorylase Reveals a Distinct Subfamily of Nucleoside Phosphorylases.
Biochemistry, 50, 2011