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1OGW
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SYNTHETIC UBIQUITIN WITH FLUORO-LEU AT 50 AND 67
Descriptor:UBIQUITIN
Authors:Alexeev, D., Ramage, R., Young, D.W., Sawyer, L.
Deposit date:2003-05-13
Release date:2003-05-30
Last modified:2011-12-07
Method:X-RAY DIFFRACTION (1.32 Å)
Cite:Synthesis, Structural and Biological Studies of Ubiquitin Mutants Containing (2S, 4S)-5-Fluoroleucine Residues Strategically Placed in the Hydrophobic Core
Chembiochem, 4, 2003
1DTY
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CRYSTAL STRUCTURE OF ADENOSYLMETHIONINE-8-AMINO-7-OXONANOATE AMINOTRANSFERASE WITH PYRIDOXAL PHOSPHATE COFACTOR.
Descriptor:ADENOSYLMETHIONINE-8-AMINO-7-OXONONANOATE AMINOTRANSFERASE, SODIUM ION, PYRIDOXAL-5'-PHOSPHATE
Authors:Alexeev, D., Sawyer, L., Baxter, R.L., Alexeeva, M.V., Campopiano, D.
Deposit date:2000-01-13
Release date:2000-02-18
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.14 Å)
Cite:Crystal structure of adenosylmethionine-8-amino-7-oxonanoate aminotransferase with pyridoxal phosphate cofactor
to be published
1BS0
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PLP-DEPENDENT ACYL-COA SYNTHASE
Descriptor:PROTEIN (8-AMINO-7-OXONANOATE SYNTHASE), SULFATE ION
Authors:Alexeev, D., Alexeeva, M., Baxter, R.L., Campopiano, D.J., Webster, S.P., Sawyer, L.
Deposit date:1998-08-31
Release date:1999-08-27
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:The crystal structure of 8-amino-7-oxononanoate synthase: a bacterial PLP-dependent, acyl-CoA-condensing enzyme.
J.Mol.Biol., 284, 1998
1O7T
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METAL NANOCLUSTERS BOUND TO THE FERRIC BINDING PROTEIN FROM NEISSERIA GONORRHOEAE.
Descriptor:IRON BINDING PROTEIN, HF OXO CLUSTER HF5, SMALLEST HF-OXO-PHOSPHATE CLUSTER HF3, ...
Authors:Alexeev, D., Zu, H., Guo, M., Zhong, W., Hunter, D.J.B., Yang, W., Campopiano, D.J., Sadler, P.J.
Deposit date:2002-11-12
Release date:2003-02-27
Last modified:2019-04-03
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:A novel protein-mineral interface.
Nat. Struct. Biol., 10, 2003
2G6W
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SUICIDE INHIBITION OF A-OXAMINE SYNTHASE: STRUCTURES OF THE COVALENT ADDUCTS OF 8-AMINO-7-OXONANOATE SYNTHASE WITH TRIFLUOROALANINE
Descriptor:8-amino-7-oxononanoate synthase, (4-{(E)-[(2,2-DIFLUOROETHYL)IMINO]METHYL}-5-HYDROXY-6-METHYLPYRIDIN-3-YL)METHYL DIHYDROGEN PHOSPHATE
Authors:Alexeev, D.
Deposit date:2006-02-26
Release date:2006-04-25
Last modified:2017-10-18
Method:X-RAY DIFFRACTION (2.14 Å)
Cite:Suicide inhibition of alpha-oxamine synthases: structures of the covalent adducts of 8-amino-7-oxononanoate synthase with trifluoroalanine.
Org.Biomol.Chem., 4, 2006
1DBS
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MECHANISTIC IMPLICATIONS AND FAMILY RELATIONSHIPS FROM THE STRUCTURE OF DETHIOBIOTIN SYNTHETASE
Descriptor:DETHIOBIOTIN SYNTHETASE, SULFATE ION
Authors:Sawyer, L., Alexeev, D.
Deposit date:1994-11-29
Release date:1995-04-20
Last modified:2017-11-29
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Mechanistic implications and family relationships from the structure of dethiobiotin synthetase.
Structure, 2, 1994
1DJ9
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CRYSTAL STRUCTURE OF 8-AMINO-7-OXONANOATE SYNTHASE (OR 7-KETO-8AMINIPELARGONATE OR KAPA SYNTHASE) COMPLEXED WITH PLP AND THE PRODUCT 8(S)-AMINO-7-OXONANONOATE (OR KAPA). THE ENZYME OF BIOTIN BIOSYNTHETIC PATHWAY.
Descriptor:8-AMINO-7-OXONONANOATE SYNTHASE, SULFATE ION, MAGNESIUM ION, ...
Authors:Webster, S.P., Alexeev, D., Campopiano, D.J., Watt, R.M., Alexeeva, M., Sawyer, L., Baxter, R.L.
Deposit date:1999-12-02
Release date:2000-12-06
Last modified:2017-10-04
Method:X-RAY DIFFRACTION (2 Å)
Cite:Mechanism of 8-amino-7-oxononanoate synthase: spectroscopic, kinetic, and crystallographic studies.
Biochemistry, 39, 2000
1DJE
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CRYSTAL STRUCTURE OF THE PLP-BOUND FORM OF 8-AMINO-7-OXONANOATE SYNTHASE
Descriptor:8-AMINO-7-OXONANOATE SYNTHASE, SULFATE ION, PYRIDOXAL-5'-PHOSPHATE
Authors:Webster, S.P., Alexeev, D., Campopiano, D.J., Watt, R.M., Alexeeva, M., Sawyer, L., Baxter, R.L.
Deposit date:1999-12-02
Release date:2000-12-04
Last modified:2018-01-24
Method:X-RAY DIFFRACTION (1.71 Å)
Cite:Mechanism of 8-amino-7-oxononanoate synthase: spectroscopic, kinetic, and crystallographic studies.
Biochemistry, 39, 2000
1XC1
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OXO ZIRCONIUM(IV) CLUSTER IN THE FERRIC BINDING PROTEIN (FBP)
Descriptor:periplasmic iron-binding protein, OXO ZIRCONIUM(IV) CLUSTER
Authors:Zhong, W., Alexeev, D., Harvey, I., Guo, M., Hunter, D.J.B., Zhu, H., Campopiano, D.J., Sadler, P.J.
Deposit date:2004-08-31
Release date:2004-09-21
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.51 Å)
Cite:Assembly of an Oxo-Zirconium(IV) Cluster in a Protein Cleft
Angew.Chem.Int.Ed.Engl., 43, 2004
1R1N
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TRI-NUCLEAR OXO-IRON CLUSTERS IN THE FERRIC BINDING PROTEIN FROM N. GONORRHOEAE
Descriptor:Ferric-iron Binding Protein, OXO-IRON CLUSTER 1, OXO-IRON CLUSTER 2, ...
Authors:Zhu, H., Alexeev, D., Hunter, D.J., Campopiano, D.J., Sadler, P.J.
Deposit date:2003-09-24
Release date:2004-03-09
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.74 Å)
Cite:Oxo-iron clusters in a bacterial iron-trafficking protein: new roles for a conserved motif.
Biochem.J., 376, 2003
4PGM
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SACCHAROMYCES CEREVISIAE PHOSPHOGLYCERATE MUTASE
Descriptor:PHOSPHOGLYCERATE MUTASE 1
Authors:Rigden, D.J., Alexeev, D., Phillips, S.E.V., Fothergill-Gilmore, L.A.
Deposit date:1997-04-25
Release date:1997-10-29
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:The 2.3 A X-ray crystal structure of S. cerevisiae phosphoglycerate mutase.
J.Mol.Biol., 276, 1998
1UBI
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SYNTHETIC STRUCTURAL AND BIOLOGICAL STUDIES OF THE UBIQUITIN SYSTEM. PART 1
Descriptor:UBIQUITIN
Authors:Alexeev, D., Bury, S.M., Turner, M.A., Ogunjobi, O.M., Muir, T.W., Ramage, R., Sawyer, L.
Deposit date:1994-02-03
Release date:1994-05-31
Last modified:2017-11-29
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Synthetic, structural and biological studies of the ubiquitin system: the total chemical synthesis of ubiquitin.
Biochem.J., 299, 1994
1BQ3
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SACCHAROMYCES CEREVISIAE PHOSPHOGLYCERATE MUTASE IN COMPLEX WITH INOSITOL HEXAKISPHOSPHATE
Descriptor:PROTEIN (PHOSPHOGLYCERATE MUTASE 1), INOSITOL HEXAKISPHOSPHATE, SULFATE ION
Authors:Rigden, D.J., Phillips, S.E.V., Fothergill-Gilmore, L.A.
Deposit date:1998-08-20
Release date:1998-08-26
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Polyanionic inhibitors of phosphoglycerate mutase: combined structural and biochemical analysis.
J.Mol.Biol., 289, 1999
1BQ4
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SACCHAROMYCES CEREVISIAE PHOSPHOGLYCERATE MUTASE IN COMPLEX WITH BENZENE HEXACARBOXYLATE
Descriptor:PROTEIN (PHOSPHOGLYCERATE MUTASE 1), SULFATE ION, BENZENE HEXACARBOXYLIC ACID
Authors:Rigden, D.J., Phillips, S.E.V., Fothergill-Gilmore, L.A.
Deposit date:1998-08-20
Release date:1998-08-26
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Polyanionic inhibitors of phosphoglycerate mutase: combined structural and biochemical analysis.
J.Mol.Biol., 289, 1999
5PGM
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SACCHAROMYCES CEREVISIAE PHOSPHOGLYCERATE MUTASE
Descriptor:PHOSPHOGLYCERATE MUTASE 1, SULFATE ION, ALANINE
Authors:Rigden, D.J., Phillips, S.E.V., Fothergill-Gilmore, L.A.
Deposit date:1998-08-19
Release date:1999-02-16
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.12 Å)
Cite:Sulphate ions observed in the 2.12 A structure of a new crystal form of S. cerevisiae phosphoglycerate mutase provide insights into understanding the catalytic mechanism.
J.Mol.Biol., 286, 1999