Author results

1AGM
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REFINED STRUCTURE FOR THE COMPLEX OF ACARBOSE WITH GLUCOAMYLASE FROM ASPERGILLUS AWAMORI VAR. X100 TO 2.4 ANGSTROMS RESOLUTION
Descriptor:GLUCOAMYLASE-471, N-ACETYL-D-GLUCOSAMINE, BETA-D-MANNOSE, ...
Authors:Aleshin, A.E., Firsov, L.M., Honzatko, R.B.
Deposit date:1994-05-13
Release date:1994-09-30
Last modified:2017-11-29
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Refined structure for the complex of acarbose with glucoamylase from Aspergillus awamori var. X100 to 2.4-A resolution.
J.Biol.Chem., 269, 1994
1CZA
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MUTANT MONOMER OF RECOMBINANT HUMAN HEXOKINASE TYPE I COMPLEXED WITH GLUCOSE, GLUCOSE-6-PHOSPHATE, AND ADP
Descriptor:HEXOKINASE TYPE I, ALPHA-D-GLUCOSE, ALPHA-D-GLUCOSE-6-PHOSPHATE, ...
Authors:Aleshin, A.E., Liu, X., Kirby, C., Bourenkov, G.P., Bartunik, H.D., Fromm, H.J., Honzatko, R.B.
Deposit date:1999-09-01
Release date:2000-03-06
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Crystal structures of mutant monomeric hexokinase I reveal multiple ADP binding sites and conformational changes relevant to allosteric regulation.
J.Mol.Biol., 296, 2000
1DGK
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MUTANT MONOMER OF RECOMBINANT HUMAN HEXOKINASE TYPE I WITH GLUCOSE AND ADP IN THE ACTIVE SITE
Descriptor:HEXOKINASE TYPE I, ALPHA-D-GLUCOSE, PHOSPHATE ION, ...
Authors:Aleshin, A.E., Liu, X., Kirby, C., Bourenkov, G.P., Bartunik, H.D., Fromm, H.J., Honzatko, R.B.
Deposit date:1999-11-24
Release date:2000-03-08
Last modified:2018-01-31
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Crystal structures of mutant monomeric hexokinase I reveal multiple ADP binding sites and conformational changes relevant to allosteric regulation.
J.Mol.Biol., 296, 2000
1DOG
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REFINED STRUCTURE FOR THE COMPLEX OF 1-DEOXYNOJIRIMYCIN WITH GLUCOAMYLASE FROM (ASPERGILLUS AWAMORI) VAR. X100 TO 2.4 ANGSTROMS RESOLUTION
Descriptor:GLUCOAMYLASE-471, N-ACETYL-D-GLUCOSAMINE, BETA-D-MANNOSE, ...
Authors:Harris, E., Aleshin, A., Firsov, L., Honzatko, R.B.
Deposit date:1993-01-12
Release date:1994-01-31
Last modified:2017-11-29
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Refined structure for the complex of 1-deoxynojirimycin with glucoamylase from Aspergillus awamori var. X100 to 2.4-A resolution.
Biochemistry, 32, 1993
1GAH
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GLUCOAMYLASE-471 COMPLEXED WITH ACARBOSE
Descriptor:GLUCOAMYLASE-471, ALPHA-D-MANNOSE, N-ACETYL-D-GLUCOSAMINE, ...
Authors:Aleshin, A.E., Stoffer, B., Firsov, L.M., Svensson, B., Honzatko, R.B.
Deposit date:1996-03-06
Release date:1996-08-17
Last modified:2018-03-21
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystallographic complexes of glucoamylase with maltooligosaccharide analogs: relationship of stereochemical distortions at the nonreducing end to the catalytic mechanism.
Biochemistry, 35, 1996
1GAI
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GLUCOAMYLASE-471 COMPLEXED WITH D-GLUCO-DIHYDROACARBOSE
Descriptor:GLUCOAMYLASE-471, ALPHA-D-MANNOSE, N-ACETYL-D-GLUCOSAMINE, ...
Authors:Aleshin, A.E., Stoffer, B., Firsov, L.M., Svensson, B., Honzatko, R.B.
Deposit date:1996-03-06
Release date:1996-08-17
Last modified:2011-10-05
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Crystallographic complexes of glucoamylase with maltooligosaccharide analogs: relationship of stereochemical distortions at the nonreducing end to the catalytic mechanism.
Biochemistry, 35, 1996
1GLM
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REFINED CRYSTAL STRUCTURES OF GLUCOAMYLASE FROM ASPERGILLUS AWAMORI VAR. X100
Descriptor:GLUCOAMYLASE-471, N-ACETYL-D-GLUCOSAMINE, ALPHA-D-MANNOSE
Authors:Aleshin, A.E., Hoffman, C., Firsov, L.M., Honzatko, R.B.
Deposit date:1994-04-25
Release date:1994-06-22
Last modified:2017-11-29
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Refined crystal structures of glucoamylase from Aspergillus awamori var. X100.
J.Mol.Biol., 238, 1994
1HKB
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CRYSTAL STRUCTURE OF RECOMBINANT HUMAN BRAIN HEXOKINASE TYPE I COMPLEXED WITH GLUCOSE AND GLUCOSE-6-PHOSPHATE
Descriptor:D-GLUCOSE 6-PHOSPHOTRANSFERASE, BETA-D-GLUCOSE, ALPHA-D-GLUCOSE-6-PHOSPHATE, ...
Authors:Aleshin, A.E., Zeng, C., Burenkov, G.P., Bartunik, H.D., Fromm, H.J., Honzatko, R.B.
Deposit date:1997-12-01
Release date:1998-06-03
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:The mechanism of regulation of hexokinase: new insights from the crystal structure of recombinant human brain hexokinase complexed with glucose and glucose-6-phosphate.
Structure, 6, 1998
1HKC
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RECOMBINANT HUMAN HEXOKINASE TYPE I COMPLEXED WITH GLUCOSE AND PHOSPHATE
Descriptor:D-GLUCOSE 6-PHOSPHOTRANSFERASE, BETA-D-GLUCOSE, PHOSPHATE ION, ...
Authors:Aleshin, A.E., Honzatko, R.B.
Deposit date:1998-07-01
Release date:1998-11-11
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Regulation of hexokinase I: crystal structure of recombinant human brain hexokinase complexed with glucose and phosphate.
J.Mol.Biol., 282, 1998
1LF6
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CRYSTAL STRUCTURE OF BACTERIAL GLUCOAMYLASE
Descriptor:glucoamylase, SULFATE ION
Authors:Aleshin, A.E., Feng, P.-H., Honzatko, R.B., Reilly, P.J.
Deposit date:2002-04-10
Release date:2003-02-25
Last modified:2018-01-31
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Crystal structure and evolution of prokaryotic glucoamylase
J.Mol.Biol., 327, 2003
1LF9
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CRYSTAL STRUCTURE OF BACTERIAL GLUCOAMYLASE COMPLEXED WITH ACARBOSE
Descriptor:GLUCOAMYLASE, ALPHA-ACARBOSE, SULFATE ION
Authors:Aleshin, A.E., Feng, P.-H., Honzatko, R.B., Reilly, P.J.
Deposit date:2002-04-10
Release date:2003-02-25
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Crystal structure and evolution of prokaryotic glucoamylase
J.Mol.Biol., 327, 2003
2GGV
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CRYSTAL STRUCTURE OF THE WEST NILE VIRUS NS2B-NS3 PROTEASE, HIS51ALA MUTANT
Descriptor:non-structural protein 2B, non-structural protein 3
Authors:Aleshin, A.E., Shiryaev, S.A., Strongin, A.Y., Liddington, R.C.
Deposit date:2006-03-24
Release date:2007-03-27
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structural evidence for regulation and specificity of flaviviral proteases and evolution of the Flaviviridae fold.
Protein Sci., 16, 2007
2I39
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CRYSTAL STRUCTURE OF VACCINIA VIRUS N1L PROTEIN
Descriptor:Protein N1, (4S)-2-METHYL-2,4-PENTANEDIOL
Authors:Aoyagi, M., Aleshin, A.E., Stec, B., Liddington, R.C.
Deposit date:2006-08-17
Release date:2006-11-21
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Vaccinia virus N1L protein resembles a B cell lymphoma-2 (Bcl-2) family protein.
Protein Sci., 16, 2007
2IJO
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CRYSTAL STRUCTURE OF THE WEST NILE VIRUS NS2B-NS3 PROTEASE COMPLEXED WITH BOVINE PANCREATIC TRYPSIN INHIBITOR
Descriptor:Polyprotein, Pancreatic trypsin inhibitor
Authors:Aleshin, A.E., Shiryaev, S.A., Strongin, A.Y., Liddington, R.C.
Deposit date:2006-09-29
Release date:2007-05-15
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structural evidence for regulation and specificity of flaviviral proteases and evolution of the Flaviviridae fold.
Protein Sci., 16, 2007
2NAC
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HIGH RESOLUTION STRUCTURES OF HOLO AND APO FORMATE DEHYDROGENASE
Descriptor:NAD-DEPENDENT FORMATE DEHYDROGENASE, SULFATE ION
Authors:Lamzin, V.S., Dauter, Z., Popov, V.O., Harutyunyan, E.H., Wilson, K.S.
Deposit date:1994-07-06
Release date:1995-01-26
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:High resolution structures of holo and apo formate dehydrogenase.
J.Mol.Biol., 236, 1994
2NAD
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HIGH RESOLUTION STRUCTURES OF HOLO AND APO FORMATE DEHYDROGENASE
Descriptor:NAD-DEPENDENT FORMATE DEHYDROGENASE, AZIDE ION, SULFATE ION, ...
Authors:Lamzin, V.S., Dauter, Z., Popov, V.O., Harutyunyan, E.H., Wilson, K.S.
Deposit date:1994-07-06
Release date:1995-01-26
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:High resolution structures of holo and apo formate dehydrogenase.
J.Mol.Biol., 236, 1994
3GLY
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REFINED CRYSTAL STRUCTURES OF GLUCOAMYLASE FROM ASPERGILLUS AWAMORI VAR. X100
Descriptor:GLUCOAMYLASE-471, N-ACETYL-D-GLUCOSAMINE, BETA-D-MANNOSE, ...
Authors:Aleshin, A.E., Hoffman, C., Firsov, L.M., Honzatko, R.B.
Deposit date:1994-06-03
Release date:1994-11-01
Last modified:2017-11-29
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Refined crystal structures of glucoamylase from Aspergillus awamori var. X100.
J.Mol.Biol., 238, 1994
3HDI
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CRYSTAL STRUCTURE OF BACILLUS HALODURANS METALLO PEPTIDASE
Descriptor:Processing protease, Synthetic peptide, COBALT (II) ION, ...
Authors:Aleshin, A., Gramatikova, S., Strongin, A.Y., Stec, B., Liddington, R.C., Smith, J.W.
Deposit date:2009-05-07
Release date:2009-12-08
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Crystal and solution structures of a prokaryotic M16B peptidase: an open and shut case.
Structure, 17, 2009
3T5O
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CRYSTAL STRUCTURE OF HUMAN COMPLEMENT COMPONENT C6
Descriptor:Complement component C6, CADMIUM ION, N-ACETYL-D-GLUCOSAMINE, ...
Authors:Aleshin, A.E., Stec, B., Bankston, L.A., DiScipio, R.G., Liddington, R.C.
Deposit date:2011-07-27
Release date:2012-02-01
Last modified:2012-04-11
Method:X-RAY DIFFRACTION (2.869 Å)
Cite:Structure of Complement C6 Suggests a Mechanism for Initiation and Unidirectional, Sequential Assembly of Membrane Attack Complex (MAC).
J.Biol.Chem., 287, 2012
4E0S
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CRYSTAL STRUCTURE OF C5B-6
Descriptor:Complement C5, Complement component C6, N-ACETYL-D-GLUCOSAMINE, ...
Authors:Aleshin, A.E., Stec, B., DiScipio, R., Liddington, R.C.
Deposit date:2012-03-05
Release date:2012-04-18
Last modified:2017-11-15
Method:X-RAY DIFFRACTION (4.21 Å)
Cite:Crystal structure of c5b-6 suggests structural basis for priming assembly of the membrane attack complex.
J.Biol.Chem., 287, 2012
4N5G
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CRYSTAL STRUCTURE OF RXRA LBD COMPLEXED WITH A SYNTHETIC MODULATOR K8012
Descriptor:Retinoic acid receptor RXR-alpha, 5-(2-{(1Z)-5-fluoro-2-methyl-1-[4-(propan-2-yl)benzylidene]-1H-inden-3-yl}ethyl)-1H-tetrazole
Authors:Aleshin, A.E., Su, Y., Zhang, X., Liddington, R.C.
Deposit date:2013-10-09
Release date:2014-05-14
Last modified:2014-06-11
Method:X-RAY DIFFRACTION (2.11 Å)
Cite:Sulindac-Derived RXR alpha Modulators Inhibit Cancer Cell Growth by Binding to a Novel Site.
Chem.Biol., 21, 2014
4N8R
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CRYSTAL STRUCTURE OF RXRA LBD COMPLEXED WITH A SYNTHETIC MODULATOR K-8008
Descriptor:Retinoic acid receptor RXR-alpha, 5-(2-{(1Z)-2-methyl-1-[4-(propan-2-yl)benzylidene]-1H-inden-3-yl}ethyl)-1H-tetrazole
Authors:Aleshin, A.E., Su, Y., Zhang, X., Liddington, R.C.
Deposit date:2013-10-17
Release date:2014-05-14
Last modified:2014-06-11
Method:X-RAY DIFFRACTION (2.03 Å)
Cite:Sulindac-Derived RXR alpha Modulators Inhibit Cancer Cell Growth by Binding to a Novel Site.
Chem.Biol., 21, 2014
4ON1
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CRYSTAL STRUCTURE OF METALLOPROTEINASE-II FROM BACTEROIDES FRAGILIS
Descriptor:Putative metalloprotease II, ZINC ION, GLYCEROL
Authors:Aleshin, A.E., Liddington, R.C., Shiryaev, S.A., Strongin, A.Y.
Deposit date:2014-01-28
Release date:2014-04-09
Last modified:2014-06-18
Method:X-RAY DIFFRACTION (2.13 Å)
Cite:Structural and functional diversity of metalloproteinases encoded by the Bacteroides fragilis pathogenicity island.
Febs J., 281, 2014
4RPI
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CRYSTAL STRUCTURE OF NICOTINATE MONONUCLEOTIDE ADENYLYLTRANSFERASE FROM MYCOBACTERIUM TUBERCULOSIS
Descriptor:nicotinate-nucleotide adenylyltransferase, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, DIMETHYL SULFOXIDE
Authors:Rodionova, I., Zuccola, H., Sorci, L., Aleshin, A.E., Kazanov, M., Sergienko, E., Rubin, E., Locher, C., Osterman, A.
Deposit date:2014-10-30
Release date:2015-01-28
Last modified:2017-12-20
Method:X-RAY DIFFRACTION (2.417 Å)
Cite:Mycobacterial nicotinate mononucleotide adenylyltransferase: structure, mechanism, and implications for drug discovery.
J. Biol. Chem., 290, 2015
4X0E
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STRUCTURE OF M. TUBERCULOSIS NICOTINATE MONO NUCLEOTIDE ADENYLYLTRANSFERASE
Descriptor:Probable nicotinate-nucleotide adenylyltransferase, SULFATE ION, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID
Authors:Zuccola, H.J., Ostermna, A.L.
Deposit date:2014-11-21
Release date:2015-01-28
Last modified:2017-12-13
Method:X-RAY DIFFRACTION (2.41 Å)
Cite:Mycobacterial nicotinate mononucleotide adenylyltransferase: structure, mechanism, and implications for drug discovery.
J. Biol. Chem., 290, 2015
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