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5H1A
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CRYSTAL STRUCTURE OF AN ICLR HOMOLOG FROM MICROBACTERIUM SP. STRAIN HM58-2
分子名称:IclR transcription factor homolog, PHOSPHATE ION
著者Akiyama, T., Yamada, Y., Takaya, N., Ito, S., Sasaki, Y., Yajima, S.
登録日2016-10-08
公開日2017-01-18
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Crystal structure of an IclR homologue from Microbacterium sp. strain HM58-2.
Acta Crystallogr F Struct Biol Commun, 73, 2017
5H6S
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CRYSTAL STRUCTURE OF HYDRAZIDASE S179A MUTANT COMPLEXED WITH A SUBSTRATE
分子名称:Amidase, 4-oxidanylbenzohydrazide
著者Akiyama, T., Ishii, M., Takuwa, A., Oinuma, K., Sasaki, Y., Takaya, N., Yajima, S.
登録日2016-11-15
公開日2017-02-01
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Structural basis of the substrate recognition of hydrazidase isolated from Microbacterium sp. strain HM58-2, which catalyzes acylhydrazide compounds as its sole carbon source
Biochem. Biophys. Res. Commun., 482, 2017
5H6T
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CRYSTAL STRUCTURE OF HYDRAZIDASE FROM MICROBACTERIUM SP. STRAIN HM58-2
分子名称:Amidase
著者Akiyama, T., Ishii, M., Takuwa, A., Oinuma, K., Sasaki, Y., Takaya, N., Yajima, S.
登録日2016-11-15
公開日2017-03-15
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Structural basis of the substrate recognition of hydrazidase isolated from Microbacterium sp. strain HM58-2, which catalyzes acylhydrazide compounds as its sole carbon source
Biochem. Biophys. Res. Commun., 482, 2017
3WG8
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CRYSTAL STRUCTURE OF THE ABSCISIC ACID RECEPTOR PYR1 IN COMPLEX WITH AN ANTAGONIST AS6
分子名称:Abscisic acid receptor PYR1, (2Z,4E)-5-[(1S)-3-(hexylsulfanyl)-1-hydroxy-2,6,6-trimethyl-4-oxocyclohex-2-en-1-yl]-3-methylpenta-2,4-dienoic acid
著者Akiyama, T., Sue, M., Takeuchi, J., Okamoto, M., Muto, T., Endo, A., Nambara, E., Hirai, N., Ohnishi, T., Cutler, S.R., Todoroki, Y., Yajima, S.
登録日2013-07-31
公開日2014-05-07
最終更新日2014-06-11
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Designed abscisic acid analogs as antagonists of PYL-PP2C receptor interactions
Nat.Chem.Biol., 10, 2014
5B2H
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CRYSTAL STRUCTURE OF HA33 FROM CLOSTRIDIUM BOTULINUM SEROTYPE C STRAIN YOICHI
分子名称:HA-33, TRIETHYLENE GLYCOL
著者Akiyama, T., Hayashi, S., Matsumoto, T., Hasegawa, K., Yamano, A., Suzuki, T., Niwa, K., Watanabe, T., Sagane, Y., Yajima, S.
登録日2016-01-15
公開日2016-06-15
最終更新日2016-07-20
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Conformational divergence in the HA-33/HA-17 trimer of serotype C and D botulinum toxin complex
Biochem.Biophys.Res.Commun., 476, 2016
5YGV
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CRYSTAL STRUCTURE OF THE ABSCISIC ACID RECEPTOR PYR1 IN COMPLEX WITH AN ANTAGONIST
分子名称:Abscisic acid receptor PYR1, (2Z,4E)-3-methyl-5-[(1S,4S)-2,6,6-trimethyl-4-[3-(4-methylphenyl)prop-2-ynoxy]-1-oxidanyl-cyclohex-2-en-1-yl]penta-2,4-dienoic acid
著者Akiyama, T., Sue, M., Takeuchi, J., Mimura, N., Okamoto, M., Monda, K., Iba, K., Ohnishi, T., Todoroki, Y., Yajima, S.
登録日2017-09-27
公開日2018-04-18
最終更新日2018-05-30
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Structure-Based Chemical Design of Abscisic Acid Antagonists That Block PYL-PP2C Receptor Interactions.
ACS Chem. Biol., 13, 2018
2J4X
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STREPTOCOCCUS DYSGALACTIAE-DERIVED MITOGEN (SDM)
分子名称:MITOGEN, ZINC ION, GLYCEROL
著者Saarinen, S., Kato, H., Uchiyama, T., Miyoshi-Akiyama, T., Papageorgiou, A.C.
登録日2006-09-07
公開日2007-09-25
最終更新日2019-07-24
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Crystal Structure of Streptococcus Dysgalactiae-Derived Mitogen Reveals a Zinc-Binding Site and Alterations in Tcr Binding.
J.Mol.Biol., 373, 2007
3QHE
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CRYSTAL STRUCTURE OF THE COMPLEX BETWEEN THE ARMADILLO REPEAT DOMAIN OF ADENOMATOUS POLYPOSIS COLI AND THE TYROSINE-RICH DOMAIN OF SAM68
分子名称:Adenomatous polyposis coli protein, KH domain-containing, RNA-binding, ...
著者Morishita, E.C.J., Murayama, K., Kato-Murayama, M., Ishizuku-Katsura, Y., Tomabechi, Y., Terada, T., Handa, N., Shirouzu, M., Akiyama, T., Yokoyama, S., RIKEN Structural Genomics/Proteomics Initiative (RSGI)
登録日2011-01-25
公開日2011-11-02
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Crystal structures of the armadillo repeat domain of adenomatous polyposis coli and its complex with the tyrosine-rich domain of sam68
Structure, 19, 2011
3GNO
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CRYSTAL STRUCTURE OF A RICE OS3BGLU6 BETA-GLUCOSIDASE
分子名称:Os03g0212800 protein, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, GLYCEROL
著者Seshadri, S., Akiyama, T., Opassiri, R., Kuaprasert, B., Cairns, J.R.K.
登録日2009-03-17
公開日2009-07-21
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.83 Å)
主引用文献Structural and enzymatic characterization of Os3BGlu6, a rice {beta}-glucosidase hydrolyzing hydrophobic glycosides and (1->3)- and (1->2)-linked disaccharides.
Plant Physiol., 2009
3GNP
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CRYSTAL STRUCTURE OF A RICE OS3BGLU6 BETA-GLUCOSIDASE WITH OCTYL-BETA-D-THIO-GLUCOSIDE
分子名称:Os03g0212800 protein, 2-HYDROXYMETHYL-6-OCTYLSULFANYL-TETRAHYDRO-PYRAN-3,4,5-TRIOL, GLYCEROL
著者Seshadri, S., Akiyama, T., Opassiri, R., Kuaprasert, B., Cairns, J.R.K.
登録日2009-03-17
公開日2009-07-21
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Structural and enzymatic characterization of Os3BGlu6, a rice {beta}-glucosidase hydrolyzing hydrophobic glycosides and (1->3)- and (1->2)-linked disaccharides.
Plant Physiol., 2009
3GNR
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CRYSTAL STRUCTURE OF A RICE OS3BGLU6 BETA-GLUCOSIDASE WITH COVALENTLY BOUND 2-DEOXY-2-FLUOROGLUCOSIDE TO THE CATALYTIC NUCLEOPHILE E396
分子名称:Os03g0212800 protein, 2-deoxy-2-fluoro-alpha-D-glucopyranose, GLYCEROL
著者Seshadri, S., Akiyama, T., Opassiri, R., Kuaprasert, B., Cairns, J.R.K.
登録日2009-03-17
公開日2009-07-21
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.81 Å)
主引用文献Structural and enzymatic characterization of Os3BGlu6, a rice beta-glucosidase hydrolyzing hydrophobic glycosides and (1->3)- and (1->2)-linked disaccharides.
Plant Physiol., 151, 2009
3W9Y
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CRYSTAL STRUCTURE OF THE HUMAN DLG1 GUANYLATE KINASE DOMAIN
分子名称:Disks large homolog 1
著者Mori, S., Tezuka, Y., Arakawa, A., Handa, N., Shirouzu, M., Akiyama, T., Yokoyama, S.
登録日2013-04-18
公開日2013-06-26
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Crystal structure of the guanylate kinase domain from discs large homolog 1 (DLG1/SAP97)
Biochem.Biophys.Res.Commun., 435, 2013
4TRW
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STRUCTURE OF BACE1 COMPLEX WITH A SYN-HEA-TYPE INHIBITOR
分子名称:Beta-secretase 1, L-alpha-glutamyl-L-isoleucyl-N-[(2R,3S)-1-{[(1S)-1-carboxybutyl]amino}-2-hydroxy-5-methylhexan-3-yl]-3-thiophen-2-yl-L-alaninamide
著者Akaji, K., Teruya, K., Akiyama, T., Sanjho, A., Yamashita, E., Nakagawa, A.
登録日2014-06-18
公開日2015-07-01
最終更新日2015-09-09
実験手法X-RAY DIFFRACTION (2.85 Å)
主引用文献Evaluation of transition-state mimics in a superior BACE1 cleavage sequence as peptide-mimetic BACE1 inhibitors
Bioorg.Med.Chem., 23, 2015
4TRY
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STRUCTURE OF BACE1 COMPLEX WITH A HEA-TYPE INHIBITOR
分子名称:Beta-secretase 1, GLU-ILE-TIH-THC-NVA
著者Akaji, K., Teruya, K., Akiyama, T., Sanjho, A., Yamashita, E., Nakagawa, A.
登録日2014-06-18
公開日2015-07-29
実験手法X-RAY DIFFRACTION (2.75 Å)
主引用文献Structure of BACE1 complex with an anti-HMC-type inhibitor
to be published
4TRZ
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STRUCTURE OF BACE1 COMPLEX WITH 2-THIOPHENYL HEA-TYPE INHIBITOR
分子名称:Beta-secretase 1, 2-thiophenyl HEA-type inhibitor
著者Akaji, K., Teruya, K., Akiyama, T., Sanjho, A., Yamashita, E., Nakagawa, A.
登録日2014-06-18
公開日2015-07-01
最終更新日2015-09-09
実験手法X-RAY DIFFRACTION (3.25 Å)
主引用文献Evaluation of transition-state mimics in a superior BACE1 cleavage sequence as peptide-mimetic BACE1 inhibitors
Bioorg.Med.Chem., 23, 2015
3AU3
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CRYSTAL STRUCTURE OF ARMADILLO REPEAT DOMAIN OF APC
分子名称:Adenomatous polyposis coli protein
著者Murayama, K., Kato-Murayama, M., Terada, T., Shirouzu, M., Yokoyama, S., RIKEN Structural Genomics/Proteomics Initiative (RSGI)
登録日2011-01-28
公開日2011-11-02
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Crystal structures of the armadillo repeat domain of adenomatous polyposis coli and its complex with the tyrosine-rich domain of sam68
Structure, 19, 2011
2DX1
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CRYSTAL STRUCTURE OF RHOGEF PROTEIN ASEF
分子名称:Rho guanine nucleotide exchange factor 4
著者Murayama, K., Kato-Murayama, M., Terada, T., Shirouzu, M., Yokoyama, S., RIKEN Structural Genomics/Proteomics Initiative (RSGI)
登録日2006-08-22
公開日2007-01-02
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.36 Å)
主引用文献Crystal structure of the rac activator, Asef, reveals its autoinhibitory mechanism
J.Biol.Chem., 282, 2007
1R77
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CRYSTAL STRUCTURE OF THE CELL WALL TARGETING DOMAIN OF PEPTIDYLGLYCAN HYDROLASE ALE-1
分子名称:Cell Wall Targeting Domain of Glycylglycine Endopeptidase ALE-1
著者Lu, J.Z., Fujiwara, T., Komatsuzawa, H., Sugai, M., Sakon, J.
登録日2003-10-20
公開日2005-04-12
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献Cell Wall-targeting Domain of Glycylglycine Endopeptidase Distinguishes among Peptidoglycan Cross-bridges.
J.Biol.Chem., 281, 2006