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5CMA
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BU of 5cma by Molmil
Anti-B7-H3 monoclonal antibody ch8H9 Fab fragment
Descriptor: Antibody ch8H9 Fab heavy chain, Antibody ch8H9 Fab light chain
Authors:Ahmed, M, Goldgur, Y, Cheng, M, Cheung, N.K.
Deposit date:2015-07-16
Release date:2015-10-28
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Humanized Affinity-matured Monoclonal Antibody 8H9 Has Potent Antitumor Activity and Binds to FG Loop of Tumor Antigen B7-H3.
J.Biol.Chem., 290, 2015
3VFG
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BU of 3vfg by Molmil
Crystal structure of monoclonal antibody 3F8 Fab fragment that binds to GD2 ganglioside
Descriptor: 3F8 Heavy Chain, 3F8 Light Chain
Authors:Ahmed, M, Goldgur, Y, Cheung, N.-K.
Deposit date:2012-01-09
Release date:2013-02-06
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:In silico Driven Redesign of a Clinically Relevant Antibody for the Treatment of GD2 Positive Tumors.
Plos One, 8, 2013
4WCZ
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BU of 4wcz by Molmil
Crystal structure of a putative enoyl-CoA hydratase/isomerase from Novosphingobium aromaticivorans
Descriptor: Enoyl-CoA hydratase/isomerase
Authors:Tkaczuk, K.L, Cooper, D.R, Chapman, H.C, Niedzialkowska, E, Cymborowski, M.T, Hillerich, B.S, Stead, M, Ahmed, M, Hammonds, J, Bonanno, J, Seidel, R, Almo, S.C, Minor, W, New York Structural Genomics Research Consortium (NYSGRC)
Deposit date:2014-09-05
Release date:2014-12-03
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (1.82 Å)
Cite:Crystal structure of a putative enoyl-CoA hydratase/isomerase from Novosphingobium aromaticivorans
to be published
4U13
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BU of 4u13 by Molmil
Crystal structure of putative polyketide cyclase (protein SMa1630) from Sinorhizobium meliloti at 2.3 A resolution
Descriptor: putative polyketide cyclase SMa1630
Authors:Shabalin, I.G, Bacal, P, Osinski, T, Cooper, D.R, Szlachta, K, Stead, M, Grabowski, M, Hammonds, J, Ahmed, M, Hillerich, B.S, Bonanno, J, Seidel, R, Almo, S.C, Minor, W, New York Structural Genomics Research Consortium (NYSGRC)
Deposit date:2014-07-14
Release date:2014-09-10
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Crystal structure of a putative polyketide cyclase (protein SMa1630) from Sinorhizobium meliloti at 2.3 A resolution
to be published
4UC0
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BU of 4uc0 by Molmil
Crystal Structure Of a purine nucleoside phosphorylase (PSI-NYSGRC-029736) from Agrobacterium vitis
Descriptor: HYPOXANTHINE, Purine nucleoside phosphorylase
Authors:Cameron, S.A, Sampathkumar, P, Ramagopal, U.A, Attonito, J, Ahmed, M, Bhosle, R, Bonanno, J, Chamala, S, Chowdhury, S, Glenn, A.S, Hammonds, J, Hillerich, B, Love, J.D, Seidel, R, Stead, M, Toro, R, Wasserman, S.R, Schramm, V.L, Almo, S.C, New York Structural Genomics Research Consortium (NYSGRC)
Deposit date:2014-08-13
Release date:2014-10-08
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Crystal Structure Of a purine nucleoside phosphorylase (PSI-NYSGRC-029736) from Agrobacterium vitis
To be published
7ATS
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BU of 7ats by Molmil
The LIMK1 Kinase Domain Bound To LIJTF500127
Descriptor: LIM domain kinase 1, N-[3-[5-(4-Chlorophenyl)-1H-pyrrolo[2,3-b]pyridine-3-carbonyl]-2,4-difluorophenyl]benzenesulfonamide
Authors:Mathea, S, Chatterjee, D, Preuss, F, Yamamoto, S, Tawada, M, Nomura, I, Takagi, T, Ahmed, M, Little, W, Mueller-Knapp, S, Knapp, S.
Deposit date:2020-10-30
Release date:2020-11-25
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:The LIMK1 Kinase Domain Bound To LIJTF500127
To Be Published
7ATU
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BU of 7atu by Molmil
The LIMK1 Kinase Domain Bound To LIJTF500025
Descriptor: (S)-2-benzyl-6-(8-chloro-5-methyl-4-oxo-2,3,4,5-tetrahydrobenzo[b][1,4]oxazepin-3-yl)-7-oxo-4,5,6,7-tetrahydro-2H-pyrazolo[3,4-c]pyridine-3-carboxamide, LIM domain kinase 1
Authors:Mathea, S, Chatterjee, D, Preuss, F, Yamamoto, S, Tawada, M, Nomura, I, Takagi, T, Ahmed, M, Little, W, Mueller-Knapp, S, Knapp, S.
Deposit date:2020-10-30
Release date:2020-12-23
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:The LIMK1 Kinase Domain Bound To LIJTF500025
To Be Published
2BBR
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BU of 2bbr by Molmil
Crystal Structure of MC159 Reveals Molecular Mechanism of DISC Assembly and vFLIP Inhibition
Descriptor: AZIDE ION, Viral CASP8 and FADD-like apoptosis regulator
Authors:Yang, J.K, Wang, L, Zheng, L, Wan, F, Ahmed, M, Lenardo, M.J, Wu, H.
Deposit date:2005-10-17
Release date:2006-02-14
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (1.2 Å)
Cite:Crystal structure of MC159 reveals molecular mechanism of DISC assembly and FLIP inhibition.
Mol.Cell, 20, 2005
2BBZ
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BU of 2bbz by Molmil
Crystal Structure of MC159 Reveals Molecular Mechanism of DISC Assembly and vFLIP Inhibition
Descriptor: Viral CASP8 and FADD-like apoptosis regulator
Authors:Yang, J.K, Wang, L, Zheng, L, Wan, F, Ahmed, M, Lenardo, M.J, Wu, H.
Deposit date:2005-10-18
Release date:2006-02-14
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (3.8 Å)
Cite:Crystal structure of MC159 reveals molecular mechanism of DISC assembly and FLIP inhibition.
Mol.Cell, 20, 2005
5DK6
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BU of 5dk6 by Molmil
CRYSTAL STRUCTURE OF A 5'-METHYLTHIOADENOSINE/S-ADENOSYLHOMOCYSTEINE (MTA/SAH) NUCLEOSIDASE (MTAN) FROM COLWELLIA PSYCHRERYTHRAEA 34H (CPS_4743, TARGET PSI-029300) IN COMPLEX WITH ADENINE AT 2.27 A RESOLUTION
Descriptor: 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase, ADENINE, GLYCINE
Authors:Himmel, D.M, Bhosle, R, Toro, R, Ahmed, M, Hillerich, B, Gizzi, A, Garforth, S, Kar, A, Chan, M.K, Lafluer, J, Patel, H, Matikainen, B, Chamala, S, Lim, S, Celikgil, A, Villegas, G, Evans, B, Love, J, Fiser, A, Seidel, R.D, Bonanno, J.B, Almo, S.C, New York Structural Genomics Research Consortium (NYSGRC)
Deposit date:2015-09-03
Release date:2015-11-04
Method:X-RAY DIFFRACTION (2.27 Å)
Cite:CRYSTAL STRUCTURE OF A 5'-METHYLTHIOADENOSINE/S-ADENOSYLHOMOCYSTEINE (MTA/SAH)NUCLEOSIDASE (MTAN) FROM COLWELLIA PSYCHRERYTHRAEA 34H (CPS_4743, TARGET PSI-029300) IN COMPLEX WITH ADENINE AT 2.27 A RESOLUTION
To be published
2M4M
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BU of 2m4m by Molmil
Solution structure of the RRM domain of the hypothetical protein CAGL0M09691g from Candida glabrata
Descriptor: hypothetical protein
Authors:Harris, R, Hillerich, B, Ahmed, M, Bonanno, J.B, Chamala, S, Evans, B, Lafleur, J, Hammonds, J, Washington, E, Stead, M, Love, J, Attonito, J, Patel, H, Seidel, R.D, Chook, Y.M, Rout, M.P, Girvin, M.E, Almo, S.C, New York Structural Genomics Research Consortium (NYSGRC), Nucleocytoplasmic Transport: a Target for Cellular Control (NPCXstals)
Deposit date:2013-02-07
Release date:2013-02-27
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:Solution structure of the RRM domain of the hypothetical protein CAGL0M09691g from Candida glabrata
To be Published
2M72
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BU of 2m72 by Molmil
Solution structure of uncharacterized thioredoxin-like protein PG_2175 from Porphyromonas gingivalis
Descriptor: Uncharacterized thioredoxin-like protein
Authors:Harris, R, Ahmed, M, Attonito, J, Bonanno, J.B, Chamala, S, Chowdhury, S, Evans, B, Fiser, A, Glenn, A.S, Hammonds, J, Hillerich, B, Khafizov, K, Lafleur, J, Love, J.D, Seidel, R.D, Stead, M, Girvin, M.E, Almo, S.C, New York Structural Genomics Research Consortium (NYSGRC)
Deposit date:2013-04-16
Release date:2013-05-15
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:Solution structure of uncharacterized thioredoxin-like protein PG_2175 from Porphyromonas gingivalis
To be Published
2M71
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BU of 2m71 by Molmil
Solution structure of the a C-terminal domain of translation initiation factor IF-3 from Campylobacter jejuni
Descriptor: Translation initiation factor IF-3
Authors:Harris, R, Ahmed, M, Attonito, J, Bonanno, J.B, Chamala, S, Chowdhury, S, Evans, B, Fiser, A, Glenn, A.S, Hammonds, J, Hillerich, B, Khafizov, K, Lafleur, J, Love, J.D, Seidel, R.D, Stead, M, Girvin, M.E, Almo, S.C, New York Structural Genomics Research Consortium (NYSGRC)
Deposit date:2013-04-16
Release date:2013-05-15
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:Solution structure of the a C-terminal domain of translation initiation factor IF-3 from Campylobacter jejuni
To be Published
2M4N
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BU of 2m4n by Molmil
Solution structure of the putative Ras interaction domain of AFD-1, isoform a from Caenorhabditis elegans
Descriptor: Protein AFD-1, isoform a
Authors:Harris, R, Hillerich, B, Ahmed, M, Bonanno, J.B, Chamala, S, Evans, B, Lafleur, J, Hammonds, J, Washington, E, Stead, M, Love, J, Attonito, J, Seidel, R.D, Liddington, R.C, Weis, W.I, Nelson, W.J, Girvin, M.E, Almo, S.C, New York Structural Genomics Research Consortium (NYSGRC), Assembly, Dynamics and Evolution of Cell-Cell and Cell-Matrix Adhesions (CELLMAT)
Deposit date:2013-02-07
Release date:2013-03-20
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:Solution structure of the putative Ras interaction domain of AFD-1, isoform a from Caenorhabditis elegans
To be Published
5M1U
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BU of 5m1u by Molmil
Solution structure of CsgF in DHPC micelles
Descriptor: Curli production assembly/transport component CsgF
Authors:Spehr, J, Schubeis, T, Ahmed, M, Ritter, C.
Deposit date:2016-10-10
Release date:2017-10-11
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:Structural and functional characterization of the Curli adaptor protein CsgF.
FEBS Lett., 592, 2018
8FMM
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BU of 8fmm by Molmil
Complex structure of wild type Troponin complex
Descriptor: CALCIUM ION, Troponin C, slow skeletal and cardiac muscles, ...
Authors:Wang, P, Ahmed, M, Sadek, H.
Deposit date:2022-12-23
Release date:2024-01-31
Method:X-RAY DIFFRACTION (3.112 Å)
Cite:Structural and Phenotypic Correction of K210del Genetic Cardiomyopathy by an FDA Approved drug
To Be Published
8FMN
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BU of 8fmn by Molmil
Complex structure of K210 deletion Troponin complex
Descriptor: CALCIUM ION, Troponin C, slow skeletal and cardiac muscles, ...
Authors:Wang, P, Ahmed, M, Sadek, H.
Deposit date:2022-12-23
Release date:2024-01-31
Method:X-RAY DIFFRACTION (3.101 Å)
Cite:Structural and Phenotypic Correction of K210del Genetic Cardiomyopathy by an FDA Approved drug
To Be Published
8FMP
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BU of 8fmp by Molmil
Complex structure of K210 deletion Troponin complex with pamidronate
Descriptor: CALCIUM ION, Troponin C, slow skeletal and cardiac muscles, ...
Authors:Wang, P, Ahmed, M, Sadek, H.
Deposit date:2022-12-24
Release date:2024-01-31
Method:X-RAY DIFFRACTION (3.24 Å)
Cite:Structural and Phenotypic Correction of K210del Genetic Cardiomyopathy by an FDA Approved drug
To Be Published
8FMQ
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BU of 8fmq by Molmil
Complex structure of K210 deletion Troponin complex with alendronate
Descriptor: CALCIUM ION, Troponin C, slow skeletal and cardiac muscles, ...
Authors:Wang, P, Ahmed, M, Sadek, H.
Deposit date:2022-12-24
Release date:2024-01-31
Method:X-RAY DIFFRACTION (3.248 Å)
Cite:Structural and Phenotypic Correction of K210del Genetic Cardiomyopathy by an FDA Approved drug
To Be Published
8FMT
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BU of 8fmt by Molmil
Complex structure of TnnT-R205L Troponin complex
Descriptor: CALCIUM ION, Troponin C, slow skeletal and cardiac muscles, ...
Authors:Wang, P, Ahmed, M, Sadek, H.
Deposit date:2022-12-24
Release date:2024-01-31
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structural and Phenotypic Correction of K210del Genetic Cardiomyopathy by an FDA Approved drug
To Be Published
8FMO
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BU of 8fmo by Molmil
Complex structure of K210 deletion Troponin complex with risedronate
Descriptor: CALCIUM ION, Troponin C, slow skeletal and cardiac muscles, ...
Authors:Wang, P, Ahmed, M, Sadek, H.
Deposit date:2022-12-24
Release date:2024-01-31
Method:X-RAY DIFFRACTION (2.612 Å)
Cite:Structural and Phenotypic Correction of K210del Genetic Cardiomyopathy by an FDA Approved drug
To Be Published
8FMS
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BU of 8fms by Molmil
Complex structure of K210 deletion Troponin complex with neridronate
Descriptor: CALCIUM ION, Troponin C, slow skeletal and cardiac muscles, ...
Authors:Wang, P, Ahmed, M, Sadek, H.
Deposit date:2022-12-24
Release date:2024-01-31
Method:X-RAY DIFFRACTION (3.435 Å)
Cite:Structural and Phenotypic Correction of K210del Genetic Cardiomyopathy by an FDA Approved drug
To Be Published
8FMR
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BU of 8fmr by Molmil
Complex structure of K210 deletion Troponin complex with ibandronate
Descriptor: CALCIUM ION, Troponin C, slow skeletal and cardiac muscles, ...
Authors:Wang, P, Ahmed, M, Sadek, H.
Deposit date:2022-12-24
Release date:2024-01-31
Method:X-RAY DIFFRACTION (3.238 Å)
Cite:Structural and Phenotypic Correction of K210del Genetic Cardiomyopathy by an FDA Approved drug
To Be Published
4MDC
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BU of 4mdc by Molmil
Crystal structure of glutathione S-transferase from Sinorhizobium meliloti 1021, NYSGRC target 021389
Descriptor: GLYCEROL, Putative glutathione S-transferase
Authors:Shabalin, I.G, Bacal, P, Cooper, D.R, Stead, M, Ahmed, M, Hammonds, J, Bonanno, J, Seidel, R, Almo, S.C, Minor, W, New York Structural Genomics Research Consortium (NYSGRC)
Deposit date:2013-08-22
Release date:2013-09-04
Last modified:2022-04-13
Method:X-RAY DIFFRACTION (1.78 Å)
Cite:Crystal structure of glutathione S-transferase from Sinorhizobium meliloti 1021
To be Published
4MOU
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BU of 4mou by Molmil
Crystal Structure of an Enoyl-CoA Hydratase/Isomerase Family Member, NYSGRC target 028282
Descriptor: CACODYLATE ION, Enoyl-CoA hydratase/isomerase family protein
Authors:Chapman, H.C, Cooper, D.R, Geffken, K.T, Cymborowski, M.T, Osinski, T, Stead, M, Hillerich, B, Ahmed, M, Bonanno, J.B, Seidel, R, Almo, S.C, Minor, W, New York Structural Genomics Research Consortium (NYSGRC)
Deposit date:2013-09-12
Release date:2013-09-25
Last modified:2022-04-13
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:Crystal Structure of an Enoyl-CoA Hydratase/Isomerase Family Member, NYSGRC target 028282
To be Published

 

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