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6R7F
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BU of 6r7f by Molmil
Structural basis of Cullin-2 RING E3 ligase regulation by the COP9 signalosome
Descriptor: COP9 signalosome complex subunit 1, COP9 signalosome complex subunit 2, COP9 signalosome complex subunit 3, ...
Authors:Faull, S.V, Lau, A.M.C, Martens, C, Ahdash, Z, Yebenes, H, Schmidt, C, Beuron, F, Cronin, N.B, Morris, E.P, Politis, A.
Deposit date:2019-03-28
Release date:2019-08-28
Last modified:2019-10-09
Method:ELECTRON MICROSCOPY (8.2 Å)
Cite:Structural basis of Cullin 2 RING E3 ligase regulation by the COP9 signalosome.
Nat Commun, 10, 2019
6R7N
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BU of 6r7n by Molmil
Structural basis of Cullin-2 RING E3 ligase regulation by the COP9 signalosome
Descriptor: COP9 signalosome complex subunit 1, COP9 signalosome complex subunit 2, COP9 signalosome complex subunit 3, ...
Authors:Faull, S.V, Lau, A.M.C, Martens, C, Ahdash, Z, Yebenes, H, Schmidt, C, Beuron, F, Cronin, N.B, Morris, E.P, Politis, A.
Deposit date:2019-03-29
Release date:2019-08-28
Last modified:2019-09-04
Method:ELECTRON MICROSCOPY (6.5 Å)
Cite:Structural basis of Cullin 2 RING E3 ligase regulation by the COP9 signalosome.
Nat Commun, 10, 2019
7AD6
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BU of 7ad6 by Molmil
Crystal structure of human complement C5 in complex with the K92 bovine knob domain peptide.
Descriptor: 1,2-ETHANEDIOL, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, CYSTEINE, ...
Authors:Macpherson, A, van den Elsen, J.M.H, Schulze, M.E, Birtley, J.R.
Deposit date:2020-09-14
Release date:2021-03-10
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (2.75 Å)
Cite:The allosteric modulation of Complement C5 by knob domain peptides.
Elife, 10, 2021
7AD7
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BU of 7ad7 by Molmil
Crystal structure of human complement C5 in complex with the K8 bovine knob domain peptide.
Descriptor: (4S)-2-METHYL-2,4-PENTANEDIOL, (CARBAMOYLMETHYL-CARBOXYMETHYL-AMINO)-ACETIC ACID, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Macpherson, A, van den Elsen, J.M.H, Schulze, M.E, Birtley, J.R.
Deposit date:2020-09-14
Release date:2021-03-10
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:The allosteric modulation of Complement C5 by knob domain peptides.
Elife, 10, 2021
8C7J
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BU of 8c7j by Molmil
Phage display derived serum albumin binding knob domain engineered within a novel VH framework 3 bispecific antibody format
Descriptor: CHLORIDE ION, Fab heavy chain with knob domain, Fab light chain
Authors:Adams, R, Macpherson, A.
Deposit date:2023-01-16
Release date:2023-06-07
Method:X-RAY DIFFRACTION (2 Å)
Cite:Serum albumin binding knob domains engineered within a V H framework III bispecific antibody format and as chimeric peptides.
Front Immunol, 14, 2023
8C7V
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BU of 8c7v by Molmil
Phage display derived serum albumin binding knob domain engineered within a novel VH framework 3 bispecific antibody format
Descriptor: Fab heavy chain, Fab light chain
Authors:Adams, R, Macpherson, A.
Deposit date:2023-01-17
Release date:2023-06-07
Method:X-RAY DIFFRACTION (1.61 Å)
Cite:Serum albumin binding knob domains engineered within a V H framework III bispecific antibody format and as chimeric peptides.
Front Immunol, 14, 2023
6R7H
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BU of 6r7h by Molmil
Structural basis of Cullin-2 RING E3 ligase regulation by the COP9 signalosome
Descriptor: COP9 signalosome complex subunit 1, COP9 signalosome complex subunit 2, COP9 signalosome complex subunit 3, ...
Authors:Faull, S.V, Lau, A.M.C, Beuron, F, Cronin, N.B, Morris, E.P, Politis, A.
Deposit date:2019-03-28
Release date:2019-08-28
Last modified:2019-09-04
Method:ELECTRON MICROSCOPY (8.8 Å)
Cite:Structural basis of Cullin 2 RING E3 ligase regulation by the COP9 signalosome.
Nat Commun, 10, 2019
6R7I
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BU of 6r7i by Molmil
Structural basis of Cullin-2 RING E3 ligase regulation by the COP9 signalosome
Descriptor: COP9 signalosome complex subunit 1, COP9 signalosome complex subunit 2, COP9 signalosome complex subunit 3, ...
Authors:Faull, S.F, Lau, A.M.C, Beuron, F, Cronin, N.B, Morris, E.P, Politis, A.
Deposit date:2019-03-28
Release date:2019-08-28
Last modified:2019-09-04
Method:ELECTRON MICROSCOPY (5.9 Å)
Cite:Structural basis of Cullin 2 RING E3 ligase regulation by the COP9 signalosome.
Nat Commun, 10, 2019
6R6H
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BU of 6r6h by Molmil
Structural basis of Cullin-2 RING E3 ligase regulation by the COP9 signalosome
Descriptor: COP9 signalosome complex subunit 1, COP9 signalosome complex subunit 2, COP9 signalosome complex subunit 3, ...
Authors:Morris, E.P, Faull, S.V, Lau, A.M.C, Politis, A, Beuron, F, Cronin, N.
Deposit date:2019-03-27
Release date:2019-08-28
Last modified:2019-09-04
Method:ELECTRON MICROSCOPY (8.4 Å)
Cite:Structural basis of Cullin 2 RING E3 ligase regulation by the COP9 signalosome.
Nat Commun, 10, 2019
6I9B
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BU of 6i9b by Molmil
NMR structure of the La module from human LARP4A
Descriptor: La-related protein 4
Authors:Conte, M.R, Martino, L, Atkinson, R.A, Kelly, G, Cruz-Gallardo, I, De Tito, S, Trotta, R.
Deposit date:2018-11-22
Release date:2019-03-13
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:LARP4A recognizes polyA RNA via a novel binding mechanism mediated by disordered regions and involving the PAM2w motif, revealing interplay between PABP, LARP4A and mRNA.
Nucleic Acids Res., 47, 2019

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